Happy new year, happy and auspicious. On the morning of January 27th, the Central Radio and Television General Station held a press conference on the Spring Festival Gala in 2022. The relevant person in charge introduced in detail a number of innovative highlights of this Spring Festival Evening.

　　Hard core technology brings all-round audio-visual enjoyment

　　In the innovative practice of building the strategic pattern of "5G+4K/8K+AI" in the Spring Festival Evening of 2022, a number of cutting-edge scientific and technological means were actively applied, making the Spring Festival Evening a big stage for the media scientific and technological innovation display of the Headquarters.

　　△ Jiang Wenbo, a member of the editorial meeting of the Central Radio and Television General Station, introduced the highlights of technological innovation in the Spring Festival Evening of 2022.

　　8K Ultra HD TV is the highest level TV standard in the world today. The main station is not only a participant in the formulation of this standard, but also a practitioner of its application. After a year’s efforts, the 8K ultra-high-definition TV standard of the main station has completed the construction of the full link system of 8K production, broadcasting, transmission and presentation. This year’s Spring Festival Gala will be broadcast live on CCTV-8K Ultra HD channel. At the same time, the city will be lit up through "100 cities and thousands of screens", and a brand-new spatial media communication matrix will be constructed by the integration of "8K ultra-high-definition channel+landmark big screen". It is worth mentioning that the audience can listen to the TV sound synchronized with the 8K ultra-high-definition big screen through the "100-screen Walkman" WeChat applet, so that people can enjoy the ultra-clear, colorful and vivid audio-visual feast in front of the outdoor big screen.

　　This year’s Spring Festival Gala used LED screen for the first time to create a 720-degree dome space, and the giant dome design made the audience and the main stage integrated. The LED screen of 4306 square meters constitutes a highly malleable three-dimensional broadcast space, which breaks through the space limitation. For the first time, the sound reinforcement system is designed by multi-point sound reinforcement in different regions, and the volume and time delay of speakers in each region are accurately controlled, creating a good listening environment for the audience.

　　In addition, there are 130 4K cameras in the studio hall. Through the real-time processing and production of the collected video stream, the wonderful free-view video content such as "time and space condensation" and "multi-dimensional transformation" can be watched continuously, which fully meets the audience’s personalized immersive viewing needs.

　　The main station also makes full use of XR, AR virtual vision technology, holographic scanning technology and 8K naked-eye 3D presentation technology to break through the time and space constraints and bring vivid stereoscopic images to the audience. The AI multi-modal moving capture system is used to collect the actor’s trajectory and figure, and the three-dimensional coordinates of the actor’s figure image are calculated in real time by AI algorithm, so that the digital model and the actor can complete the action performance synchronously, efficiently and accurately, and create a magical visual effect of virtual and real interaction.

　　The content is novel and unique, restoring the true nature of life

　　The 2022 Spring Festival Gala adheres to the main tone of "happiness, auspiciousness and jubilation", adheres to the creative principle of "keeping integrity, innovating and creating new colors", pays attention to the organic combination and mutual transformation of ideas, art and technology, and strives to show the real and simple life with rich program styles, and highlights the annual flavor of reunion, reunion and unity in a festive and warm atmosphere.

　　△ Wang Xiaozhen, member of the editorial meeting of the Central Radio and Television General Station and director of the editorial office, introduced the overall preparations for the Spring Festival Evening in 2022.

　　The whole party not only has many kinds of programs familiar to the audience, such as language, song and dance, folk art, magic acrobatics, etc., but also has creative programs full of innovative atmosphere and high-tech means, creating a strong atmosphere of family reunion and happiness, and at the same time showing the world the festive colors of China’s land to bid farewell to the old and welcome the new, and Chinese people around the world to welcome the traditional festivals.

　　Language programs immerse the heart, feelings and thoughts into daily life, and strive to show various life appearances through different observation angles. There are warm comedies that reflect the deep affection between father and son, the relationship between mother-in-law and daughter-in-law, stories that satirize dishonest behavior, and cross talk performances that imitate others … … Let everyone feel colorful life in knowing laughter.

　　Song-and-dance programs will use a series of affectionate works to show the true feelings and the beautiful picture of the times, and carry forward and inherit the excellent Chinese traditional culture. Among them, there are not only carefully created new tracks, but also well-known classic melodies, showing China’s innovative changes, beauty of the times and forge ahead in the new era.

　　△ 8K TV set displayed on site

　　This year’s Spring Festival Evening also paid special attention to inviting many famous old artists such as Li Xuejian to be present, and gathered in the studio with a group of young and middle-aged powerful actors to join the people of the whole country in bidding farewell to the old year and welcoming the new year.

　　Cross-screen gala

　　The "Spring Festival Evening Broadcast Matrix" forms a "blowing open the petals of ten thousand pear trees" trend.

　　The Spring Festival Gala has gone through forty years, which is the emotional sustenance and aesthetic enjoyment of the vast audience, and it is also a beautiful companion for family reunion. This year, the reception desk will launch "Watching the Spring Festival Evening with Vertical Screen" for the first time, providing a brand-new visual experience for the audience. The system will realize the mixed production and broadcasting of high-definition and 4K new media signals on the spot with lightweight and all-IP deployment, and the unified switching of horizontal and vertical screens, so as to realize the new mode of "cross-screen" live broadcast in the Spring Festival Evening of 2022. Users can independently choose fresh viewing angles through new media platforms such as CCTV video, CCTV news and CCTV literature and art, highlighting the youth and new vitality of the Spring Festival Evening.

　　In addition, a series of wonderful programs, such as While the Spring Festival Gala is Going on, The Year of Dragon and Tiger Leaping in China, The Legendary China Festival, will form a "Spring Festival Gala Broadcasting Matrix", which will extend the joy, auspiciousness and jubilation of the Spring Festival Gala to the whole Spring Festival holiday and accompany the broad audience to have a happy reunion year.

　　On New Year’s Eve, "Spring Festival Gala 2022" will be broadcast simultaneously on CCTV comprehensive channel, variety channel, Chinese international channel, national defense and military channel, children’s channel, agricultural and rural channel, Olympic channel, 4K/8K ultra-high-definition channel and other broadcasting frequencies, such as the sound of literature and art, the sound of music, classical music broadcasting, the sound of Greater Bay Area, the sound of the South China Sea, the sound of Taiwan and the sea, Chinese global broadcasting and China traffic broadcasting.

　　At the same time, CCTV video, CCTV news new media, CCTV network, cloud listening and other new media platforms are broadcast simultaneously. CGTN (China International Television) English, Spanish, French, Arabic and Russian channels and 44 foreign new media platforms will link more than 600 media in more than 170 countries and regions around the world to broadcast and report the Spring Festival Gala live.

　　Starting from the "new", give your heart and soul. The reception desk will use the next few days to polish every program carefully, and go all out to create a successful, wonderful and unforgettable Spring Festival Gala, and create a happy, festive and peaceful China Year with a well-cooked dinner. Let’s meet in the Spring Festival Evening and go to spring together!

Guo Liang was an early proletarian revolutionary of our party, a famous leader of the workers’ movement, and a close comrade-in-arms who organized and led the workers’ movement with Mao Zedong. Mao Zedong praised him as "a famous organizer of the workers’ movement". On March 29th, 1928, Guo Liang was secretly killed by Kuomintang reactionaries in Qianping, Simenkou, Changsha, at the age of 27. In Guo Liang’s short life, although there are not many poems left behind, they show Shi Ce’s unyielding heart and courage to fight.

"Ask the society, what is the truth?"

Guo Liang, formerly known as Guo Jing Jia, was born in 1901 in Wenjiaba, Sheshan, Tongguan Town, Wangcheng County, Hunan Province (now Guo Liang Village, Tongguan Street). At the age of 11, he changed his name to Guo Liang, hoping to be as resourceful as Zhuge Liang. When Guo Liang was a teenager, he paid close attention to the poor life of the people who were hungry and toiling, and thought deeply about it. He wrote a sharp new-style poem "Ask the Society": A strange question is not worth mentioning by scholars and juren, and it is also common sense for teachers, but they know nothing about it! Where did the Gu Mi of the rich come from? Why do farmers carry grain into the rich man’s barn? Ask the society, what is the truth? Where did the rich man’s house come from? Why do poor people build houses and rich people live in peace? Ask the society, what is the truth? Where do the clothes of the rich come from? Why don’t people who grow cotton and weave clothes cover their bodies? Ask the society, what is the truth? People live in the same world, why are the rich and the poor different? Ask the society, what is the truth? This poem tells the people’s sufferings in plain language and lashes out at social injustice in extremely sharp language, which is particularly easy to resonate and soon spread.

It is also in order to answer these doubts in Ask the Society that Guo Liang read more and more historical books, cared about his family and country, and began to explore the truth actively. In the autumn of 1915, 14-year-old Guo Liang was admitted to Changjun Middle School. With the anti-Japanese patriotic struggle of Hunan people constantly emerging, Guo Liang participated in the patriotic anti-Japanese struggle of Changsha students. In 1916, Guo Liang saw the heads of the murdered revolutionaries on the streets of Changsha, and angrily chanted poems: "How much blood and tears are there?"? Revenge needs to pour water into the cave, and patriotism can’t be afraid of hanging its head! " Grief and indignation gushed out from this poem, and the patriotic fire took root in the young man’s heart.

"A trickle of water sinks into a huge stream"

Once the patriotic fire is lit, it burns in Guo Liang’s young chest. He sympathized with the sufferings of the people and helped the poor to destroy their homes. In the process of dealing with the masses, I also deeply felt the turbulent but confused revolutionary enthusiasm. It seems that Guo Liang, who is surrounded by mountains and mountains, is eager to explore the way of struggle and the direction of progress. In 1919, Mao Zedong founded Xiangjiang Review in Changsha to spread and introduce new ideas. Guo Liang, who has been trying hard to explore the road of saving the country and the people, was struck by Mao Zedong’s article and soon became a loyal reader of Xiangjiang Review. In 1920, Guo Liang was admitted to Hunan No.1 Normal University, and met Mao Zedong by chance. From then on, he often asked Mao Zedong for advice on how to reform the society. Introduced by Mao Zedong, Guo Liang joined Xinmin Society, and then participated in Hunan Marxist Research Association organized by Mao Zedong, He Shuheng and Fang Weixia. In the practice of struggle, Guo Liang began to have a clear revolutionary ideal and struggle ideas, and firmly believed that nothing could be done without transforming the country.

In the winter of 1921, introduced by Mao Zedong, Guo Liang joined the Communist Party of China (CPC) and became one of the earliest party member in Hunan. When joining the party, Guo Liang made a generous statement: "Some people just give an empty mouth, and I, Guo Liang, are willing to give my head to the party." Guo Liang, who joined the Communist Party of China (CPC), finally belonged, and wrote a poem to express his feelings: "A trickle of water sinks into a huge stream, and it turns around without stopping; The back waves push the front waves and fly over the mountains to be free. " He compared his personal strength to a trickle, which, once put into the arms of the Party organization, converged into stormy waves and condensed into a majestic force of revolutionary struggle under the guidance of party flag.

"When will I wash away all my worries?"

After gloriously joining the Party, Guo Liang became more and more mature in thought, and more and more deeply realized that only by mobilizing millions of working people to work together can the action of saving the country have a steady stream of power. In the summer of 1922, after graduating from Hunan No.1 Normal School, Guo Liang immediately joined the revolutionary movement. In August of the same year, appointed by Mao Zedong, Guo Liang went to Yuezhou to carry out the work of Guangdong-Han railway labor movement. When he sailed down the Xiangjiang River to Dongting Lake, he was full of thoughts and couldn’t help chanting, "Xiao Shui, Xiang Shui, flows into the Yangtze River without a head." Long Jun sent me Dongting water, when will I wash away all my worries? " Guo Liang knew that the trip was bumpy and arduous, but he had no time to think about the severity of the difficulties, but immediately devoted himself to the fiery labor movement. On September 9th, Guo Liang organized and led a strike of 3,000 workers on the Guangdong-Han Railway, which shocked the whole country and opened the prelude to the first labor movement climax in Hunan. At the end of the same year, Guo Liang led the kindling of the workers’ movement to his hometown Tongguan. In the struggle, Guo Liang made good use of concise language to complain about the sufferings of ceramic workers, such as: "Digging clay bent his waist, pushing clay bowed his back, burning kiln goods burned his heart, making kiln goods worn his hand, and selling kiln goods lost his leg." In a few words, the injustice of the poor life of ceramic workers for generations was revealed, which aroused the workers’ resonance, condensed the struggle force, led the ceramic workers to resist the so-called "kiln door tax" and organized the establishment of the Tongguan ceramic trade union. On the day when the Tongguan Ceramics Trade Union was established, the Hunan District Committee of the Communist Party of China sent a pun couplet. The first part is "Don’t say that loose sand can’t make a great instrument", and the second part is "You should know that soil can turn into gold".Highly praised Guo Liang for leading generate, a ceramic worker.

In leading the Guangdong-Han railway workers’ strike, the pottery workers’ struggle against taxes and taxes, and the Changsha workers’ struggle against imperialism and feudal warlords, Guo Liang has increasingly demonstrated his ability to approach and inspire the masses. At that time, Bolshevik, the central theoretical publication, commented on Guo Liang: Guo Liang was the pioneer of Hunan workers’ movement. Anyuan in Jiangxi, Shuikoushan in Hunan, Changsha, Guangdong, Han and Zhuping in Hunan, Hubei and Jiangxi provinces, these local workers and other industrial professional workers all organized struggles under his direct and indirect guidance.

"Heroes have never bowed their heads since ancient times."

"Xiang water stirs up the hatred of the river, and the sword breaks the water and flows more. Although good and evil are reversed, heroes have never bowed their heads since ancient times. " This poem was sung by Guo Liang on the way to Wuchang after he was arrested by the enemy. It not only expressed his resentment of "the inversion of good and evil", but also showed his heroic spirit of being fearless and dying. In July, 1924, after Guo Liang was elected as the chairman of Hunan Anti-Imperialism Alliance, he wrote a lot of campaign articles. Under the careful organization of Guo Liang, Hunan once again set off an anti-imperialist climax. Guo Liang, who was at the forefront of the struggle, was wanted several times by Zhao Hengti, the warlord of Hunan at that time. In the face of the wanted notice, Guo Liang laughed it off without fear, and wrote a doggerel: "Zhao thief is persistent, a man looks like a wolf, killing with one hand and burning incense with the other, shouting autonomy and secretly communicating with the powers. If this cub is not removed, the people will suffer, and they will get a dog’s head and a pair of copper coins. Advise the police, don’t be fooled, help the tiger eat, and it will come to no good end. The notice is integrated, so remember to be detailed. " This limerick exposes the ugly face of reactionaries in laughing and cursing, and also points out the direction of struggle for the people in plain language. Under the leadership of Guo Liang and other comrades, anti-imperialist and patriotic activities in Hunan have become increasingly frequent and powerful. Facing the great revolutionary situation, Guo Liang and his comrade-in-arms Xia Minghan touched the scene and recited poems. Guo Liang recited: "One sword hangs on the bedside, and the GREAT GHOST kid comes in." Xia Minghan replied, "Kill all demons and level the world, and the mountains, rivers, the sun and the moon will be rearranged." The two revolutionary heroes expressed their aspirations with poems, and their determination to fight to the end jumped to the page.

In January 1928, dispatched by the CPC Central Committee, Guo Liang served as the secretary of the special committee of Hunan, Hubei and Jiangxi. Under the leadership of his organization, the party organizations in the border areas of Hunan, Hubei and Jiangxi provinces have been restored and developed. On March 27th, Guo Liang was arrested in Yueyang because of a traitor’s informer, and was executed secretly by the reactionary authorities in the early morning of 29th. Before his execution, he wrote a cone-shaped suicide note to his wife, who is also a native of communist party: "Can Ying, my love: Bright running around, homeless and stateless. I’m done. Hope to be kind and caress my son to follow my ambition. This is awkward. " This touching suicide note not only expresses deep attachment to family members, but also expresses infinite expectations for future generations to continue their struggle.

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The interior design of Pentium pony fully embodies the simple and practical style. The steering wheel is made of plastic, which is not full of advanced feeling, but it ensures the portability and durability of operation. The center console is equipped with a concise control panel, integrated with an easy-to-operate multimedia screen, and provided with USB interfaces, including one in the front row, which is convenient for drivers and passengers to connect electronic devices. The seat is made of fabric, which makes it comfortable to sit. The main seat supports front and rear adjustment and backrest adjustment, and the co-pilot seat is also equipped with front and rear and backrest adjustment functions to meet the needs of different drivers. The rear seats support the proportional tilting, which provides greater flexibility for the interior space, and is convenient for loading goods or meeting the needs of family travel. On the whole, the interior design of Pentium pony pays attention to practicality and humanized configuration.

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The third week of May every year is "National Nutrition Week", and this year’s theme is "Whole grain, nutrition+,opening a new era of nutritious and healthy grains". In the new version of Dietary Guidelines for China Residents (2016), the first core recommendation mentions cereals: there are various foods, and cereals are the main ones. What does the grain include? Where is the whole grain? How much grain should we eat every day? Today, Xiaobian will give you a "past lives" of grain.

What is whole grain?

Whole grain refers to the whole grain and its natural nutrients that have not been refined (or processed by grinding and crushing). Compared with refined grains, whole grains contain more B vitamins, minerals, dietary fiber, phytochemicals, tannins, carotenoids, phytic acid, lignin and lignans. Common varieties are grain amaranth, barley, buckwheat and so on. "Whole grain" retains all kinds of nutrients and active ingredients in the grain to the maximum extent, and its health effects in preventing chronic diseases and other fields are remarkable.

How much grain do you want to eat every day?

Dietary Guidelines for China Residents (2016) suggests that healthy adults should consume 250g-400g of cereals and potatoes every day, which is equivalent to 1 small bowl of rice or 1 medium-sized steamed bread per meal. The whole grain and miscellaneous beans are not less than one third (50-150g).

What are the benefits of eating whole grains often?

According to the data of the Whole Grains Council of the United States, eating whole grains regularly can effectively reduce the risk of some chronic diseases, such as type 2 diabetes by 21-30%, cardiovascular disease by 25-28% and stroke by 30-36%. It can also reduce the risk of obesity, colorectal cancer, asthma and inflammatory diseases, maintain normal blood pressure, reduce gum disease and prevent tooth loss.

How to select whole grains

1. According to the suggestion of USDA, firstly, check whether there is the word "whole" in the ingredient list, such as whole oats, whole wheat flour, whole grain corn and whole rye.

2. Even if some foods are marked with "multi-grain", "100% wheat", "high-fiber" and "whole wheat", in fact, they are only added with bran, lacking germ, and do not belong to whole grains, so they need to be carefully recognized when purchasing.

3. When choosing oatmeal, try to choose "pure oatmeal" instead of "nutritious oatmeal" with various ingredients, such as white sugar and vegetable oil powder. "Pure oatmeal" contains higher nutrients, such as dietary fiber, and more sugar and fat in "nutritious oatmeal" is not conducive to cardiovascular health.

Content source: Beijing Nutrition Society

Video shooting/video editing: Liang Xuhao

Luo Zhengxiang, reporter Liang Yihao, photo

[Guangdong famous doctor who has been a doctor for 70 years]

Jinyang. com reporter Feng Xixi correspondent Yue Weixin Zhang Lanxi Zhang Lingling Yuting

Professor Luo Zhengxiang, 93, is a famous expert in cardiothoracic and vascular surgery in China. He used to be the president of Guangdong Provincial People’s Hospital and the director of Guangdong Institute of Cardiovascular Diseases. From a handsome young boy to a white-haired old man today, years have left traces, but he can never change the "passion" in his heart-"saving lives" is his lifelong pursuit.

Under his leadership, Guangdong took the lead in establishing the Institute of Cardiovascular Diseases in China, and its reputation is still far-reaching. This famous cardiovascular expert also won the honor of "Outstanding Contribution Award of China Cardiothoracic Surgery".

The "best student" was admitted to medical college.

Luo Zhengxiang, 93, has gray hair, but his figure is straight. He is still a handsome elder in a suit. His thinking is very clear. When he is free, he watches movies and listens to classical music. When he goes out, he takes a mobile phone and "scans the code to pay" like a young man. He is a "grandfather". This "post-90 s" grandfather has made outstanding contributions to the development of cardiovascular disease in China.

In 1947, Luo Zhengxiang did not study business or economics as expected by his father. "When I was a child, I loved reading history books and wanted to be a hero. At that time, the best students could be admitted to medical school, so I went after the hardest." With an indomitable spirit, he successfully passed the West China University of Medical Sciences.

In 1954, Luo Zhengxiang came to work in Guangdong Provincial People’s Hospital, and chose the most difficult and complicated major in the medical field at that time-cardiac surgery. Since then, he has embarked on a journey of "heart" for more than half a century.

Cardiac surgery was difficult to start in China at that time. But Luo Zhengxiang never gave up his research on heart disease-heart surgery is extremely demanding, starting with the most basic hemostasis practice. The great blood vessel was accidentally broken and the blood was shocking. Luo Zhengxiang looked at the shadowless lamp, pressed it, pressed it, pinched it, and stitched the wound with a big curved needle. He was calm and calm for a few times: OK. The valves are stitched one by one, and repeated actions are done over and over again, which is simple and boring. 1 hour, 2 hours … Some doctors have been standing on their legs and looking at them, but Luo Zhengxiang is staring, unhurried and meticulously crafted.

"I used to have surgery and the conditions were very bad. Eating a dollar at noon is simple; There is no air conditioning in the operating room. Everyone is sweating after the operation and can only drink more water after the operation. " Luo Zhengxiang said that although the conditions are difficult, everyone can work together with Qi Xin. "The director of the department takes the lead in suffering, and the doctors and nurses will follow suit. This is a kind of atmosphere and a kind of culture."

The first generation of artificial biological heart valve in China has been developed.

In 1974, after visiting Beijing, Shanghai and Guangzhou, Argentine cardiovascular experts decided to invite Guangdong experts to study cardiovascular technology in Argentina. On March 16th, 1974, a technical team organized by the Ministry of Health, mainly from Guangdong Provincial People’s Hospital (Xiang Xiangyao, Luo Zhengxiang, Chen Chuanrong, Wei Wanchang, Chen Zhiming, Wang Tailai and Jin Si Lan from the First Affiliated Hospital of Sun Yat-sen Medical College) went to Argentina for a one-year medical investigation. This year’s study was fruitful, and Luo Zhengxiang and his party brought back advanced valve technology. In 1977, Luo Zhengxiang and Cai Zengxin went to an Italian hospital in Argentina again to study heart valve technology. In 1975, the first domestic aortic valve replacement was successfully implemented, and the first domestic pediatric valve replacement was successfully implemented in the same year …

In the 1970s, rheumatic heart disease and rheumatic fever prevailed in southern China, but for these patients who need valve replacement, heart valves need to be imported, which is expensive and few people can afford it. Luo Zhengxiang and his colleagues are determined to make Chinese’s own heart valve. In 1976, Guangdong Institute of Cardiovascular Diseases set up a research room for artificial heart biological valves, and then cooperated with Australian medical expert Dr. Zhang Renqian to set up Pacific Biological Products Company in Huangpu District of Guangzhou with full reference to international standards to develop and produce artificial heart valves. In 1977, the first generation of artificial biological heart valve in China, Guangdong Type I, was developed and applied in clinic, taking the lead in the perioperative management of cardiac surgery and the application of intra-aortic balloon counterpulsation in critical heart surgery. In 1987, Guangdong II artificial heart biological valve was successfully developed, and in 1988, the artificial mechanical heart valve was successfully developed in cooperation with Australian experts and applied in clinic. Domestic valves greatly reduce the cost of patients’ surgery and shorten the gap between cardiothoracic surgery in China and advanced countries in the world.

3. Lead the Institute of Mind Research to break through difficulties and create brilliance.

In 1958, Guangdong Provincial Institute of Thoracic Diseases was established in Guangdong Provincial People’s Hospital. For various reasons, the development of the institute was quite tortuous. On August 7th, 1978, Guangdong Provincial Party Committee agreed to rename Guangdong Thoracic Disease Research Institute as "Guangdong Cardiovascular Disease Research Institute", and the Ministry of Health listed Guangdong Cardiovascular Disease Research Institute as one of the three key cardiovascular disease research institutes in China (Beijing, Shanghai and Guangdong).

In this way, the Guangdong Institute of Cardiovascular Diseases was established, but how to go next is a problem that Luo Zhengxiang has to face. Now, 93-year-old Luo Zhengxiang goes back to the Institute every day to see this old place where he has been "cultivating" for decades. Every time he walks past the entrance of Dongchuan Road, Guangzhou, he will think of the difficulties of that year: "The Institute had no funds at first, and we ran to the cement factory to find the cement. I wear leather shoes to the construction site every day to supervise the work. After that, I change my clothes and go back to the operating room for surgery. " In this way, with the concerted efforts of everyone’s Qi Xin, the Institute of Mind Research has grown up slowly.

Today, it has gone through 61 years. Over the past 61 years, the Institute has trained a large number of experts for the country, treated tens of thousands of patients and laid the foundation for the prevention of cardiovascular diseases. Created countless national firsts, first cases, and even world firsts.

Young doctors love to chat with Luo Zhengxiang, and he is also willing to communicate with young people. He said that he likes to chat with patients when he sees a doctor, and it is easier to build trust when he gets familiar with each other. "When you are a doctor, you must be dedicated to the patient and do everything for the patient; I have been a doctor for decades, and some patients have not been saved, but no one has ever made trouble, because they all know that I am saving with my heart. Whether the doctor is careful or not can be seen by patients and their families. "

[famous doctor said]

When you are a doctor, you should devote yourself to the patients.

When you are a doctor, you should be dedicated to the patient and do everything for the patient; I have been a doctor for decades, and some patients have not been saved, but no one has ever made trouble, because they all know that I am trying to save them.

　　On Tuesday (April 2), Eastern Time, the second quarter of the US stock market seemed to have a bad start. The three major indexes of the US stock market fell across the board overnight. They all fell more than 1% in intraday trading, and the Dow fell nearly 400 points to a two-week low, the biggest daily decline in four weeks with S&P. The expectation of interest rate cuts in the first half of the year was frustrated, and the yield of US bonds rose again, which suppressed the market to some extent. However, the performance of gold is still strong and continues to refresh.

　　At the close, the S&P 500 index fell 0.72% to 5205.81 points; The Dow Jones index fell 1.00% to 39,170.24 points; The Nasdaq index fell 0.95% to 16,240.45.

　　In terms of US bond yield, the 10-year US bond yield once rushed above 4.4% to close at 4.36%, and the 2-year US bond yield, which is most sensitive to the Fed’s policy interest rate, closed at 4.70%.

　　Since Powell reiterated last week that he was in no hurry to cut interest rates, the market sentiment has not been high. And overnight, internal officials of the Federal Reserve once again consolidated this statement, and market sentiment was once again hit.

　　San Francisco Fed President Daley said that three interest rate cuts this year are a baseline forecast and can be increased or decreased if necessary. The former "big hawk" and Cleveland Fed President Meister also expect to cut interest rates three times this year, and it is not excluded to cut interest rates in June, and the reasons for cutting interest rates in May are insufficient; Both warned of the risk of cutting interest rates prematurely.

　　It is worth noting that the economic data of the United States even triggered speculation about whether the Fed will cut interest rates three times this year. The data released on Tuesday showed that the number of job vacancies in the United States has not changed much compared with the previous value, or it indicates that the labor demand is still stable at a high level in the high interest rate environment.

　　LPL Financial analysts pointed out that although the Fed does expect to cut interest rates sometime this year, the argument that interest rates will be higher for a longer period of time is playing a role again, so this worries the market. He also explained from another angle why the market will pull back. A healthy market really needs to pull back. The current trend is not necessarily a bad thing. The S&P 500 index has still risen by about 9% so far this year. Therefore, the market outlook still needs to keep a close eye on the US economic data.

　　On the enterprise side, Tesla released the latest car delivery data, which was not as good as the market expectation. The share price fell by 4.9% overnight, and it has fallen by nearly one-third during the year, and its market value has been erased by 260 billion US dollars. The data shows that Tesla’s delivery volume in the first quarter decreased by 8.5% year-on-year to about 386,800 vehicles, which was far lower than the analyst’s previous average expectation of 449,080 vehicles, which was the biggest worse than expected in history. During the same period, about 433,400 vehicles were produced, which was also lower than expected.

　　This is also the first time that Tesla has fallen below the 400,000-vehicle mark since the third quarter of 2022, a decrease of over 8.5% compared with the delivery of 422,875 vehicles in the first quarter of last year, recording the first year-on-year decline since the second quarter of 2020.

　　In the first quarter, Tesla faced a double blow of reduced demand for electric vehicles and high interest rates. Analysts had previously lowered their expectations for Tesla’s delivery. Some analysts pointed out that Tesla would experience the first year-on-year sales decline since the early days of the epidemic.

　　In addition, Tesla also faced many obstacles in the first quarter, such as the interruption of the supply of spare parts in the Red Sea caused by the attack of Houthi militia and the temporary suspension of production in the German factory. Although the next generation model is the key to growth, the production of this model is not expected to start until late next year, which means that the company may face the risk of slowing down growth before this.

　　[Hot stocks]

　　Among the popular US stocks, Microsoft fell by 0.74%, Google A by 0.60%, NVIDIA by 1.01%, Amazon by 0.16%, Apple by 0.70%, Meta by 1.23%, AMD by 2.53%, Arm Holdings by 2.07% and Netflix by 0.02%.

　　Due to the delivery of Q1 far less than expected, Tesla fell by 4.9%, and has fallen by nearly one-third during the year.

　　Global stock index

　　In the European stock market, the FTSE 100 index in Britain fell slightly by 0.22% to 7935 points. The French CAC40 index fell slightly by 0.92% to 8130 points. Germany’s DAX index fell 1.13% to 18,283 points.

　　In Asian stock markets, the Hang Seng Index rose 2.36% to 16,932 points. The index of state-owned enterprises rose 2.58% to 5961 points. The Nikkei 225 index fell 0.73% to 39,625 points.

　　[China Stock Market]

　　Nasdaq China Jinlong Index closed up 0.32%. In terms of popular Chinese stocks, Pinduoduo fell by 0.77%, TSMC by 0.88%, Weilai by 2.16%, Xpeng Motors by 2.26%, Alibaba by 0.61%, Baidu by 0.08% and Netease by 1.88%.

　　[foreign exchange commodities]

　　The US dollar index rose first and then fell, once standing above the 105 mark in intraday trading, and once fell to an intraday low of 104.67 during the US session, then rebounded and finally closed down by 0.19% to 104.81.

　　Gold futures for June delivery in the New York Mercantile Exchange closed up 1.09% at $2,281.80 an ounce, a record closing high, having risen to $2,297.70 an ounce in intraday trading. May silver futures closed up 3.39% at $25.923 an ounce.

　　Geopolitical risks have enhanced the attractiveness of gold, while traders have avoided the shadow cast by the strong economic data of the United States on the prospect of the Fed raising interest rates.

　　Oil prices continue to rise due to supply concerns. WTI crude oil rushed above $85 in intraday trading, rising more than 2% in the day, and continued to hit a new high since October last year, finally closing up 1.76% to $85.47/barrel; Brent crude oil also hit a new high since October last year, and finally closed up 2.12% to $89.27/barrel.

　　[Highlights]

　　The Fed reiterated that it is not in a hurry to cut interest rates, but it is still possible to start in June?

　　San Francisco Fed President Daley said that three interest rate cuts this year are a baseline forecast and can be increased or decreased if necessary. Regardless of changing the inflation target, the continuous rise in oil prices will become a problem; The former "Great Hawk" and Cleveland Fed President Meister also expect to cut interest rates three times this year, and it is not excluded to cut interest rates in June, and the reasons for cutting interest rates in May are insufficient; Both warned of the risk of cutting interest rates prematurely.

　　Job vacancies in the United States in February were slightly higher than expected

　　The voluntary turnover rate is the lowest since 2020, and the number of layoffs is the highest in nearly a year. The number of JOLTS vacancies in the United States in February was 8.756 million, slightly better than expected, and the value was revised down to 8.748 million before January. The voluntary turnover rate in February was 2.2%, the lowest level since 2020. Due to the increase in layoffs in the leisure and hotel industries, the number of layoffs has risen to the highest level in the past year.

　　Tesla’s quarterly delivery dropped for the first time in nearly four years, and its market value has evaporated by $260 billion in the year.

　　On Tuesday, Tesla Corporation, an American electric vehicle manufacturer, released a report on automobile production and delivery in the first quarter of 2024. According to the specific data, Tesla delivered a total of 386,810 vehicles in the first three months of this year, far below the analyst’s previous average expectation of 449,080 vehicles, which was the biggest worse than expected. This is also the first time that the company has fallen below the 400,000-vehicle mark since the third quarter of 2022, which is over 8.5% lower than the delivery of 422,875 vehicles in the first quarter of last year, recording the first year-on-year decline since the second quarter of 2020.

　　Intel’s report shows that the loss of its foundry business expanded in 2023.

　　In a document submitted by Intel on Tuesday, Intel said that the sales of its new manufacturing division, Intel Foundry, in 2023 were $18.9 billion, down from $27.5 billion in the previous year, and the operating loss increased from $5.2 billion in 2022 to $7 billion. It is estimated that the loss will reach its peak in 2024 and will be realized at the operational level "in the middle of now to the end of 2030". Intel shares fell more than 2% after the report was released. Intel’s entry into outsourcing chip production is one of the biggest transformations in the company’s history. CEO Pat Gelsinge’s recovery plan also includes restoring the company’s once impeccable technological advantage, which the chip giant lost in the years before he took office in 2021.

　　A major breakthrough in AI pharmaceutical! Stanford SyntheMol model develops new antibiotics

　　According to a report by Stanford Medical College on March 28th, researchers from Stanford Medical College and McMaster University have made important progress in this field. They have developed an AI model called SyntheMol, which can synthesize drugs and create formulas for chemists in the laboratory.

　　The model creatively designed six new drugs for drug-resistant bacterial strain Acinetobacter baumannii, which is one of the main pathogens causing antibiotic resistance-related deaths. The model not only created a new drug structure, but also provided a detailed formula for chemical synthesis, enabling chemists to synthesize these drugs in the laboratory.

　　Abbott’s heart valve repair system has been approved by FDA to provide patients with new treatment options.

　　On Tuesday, US medical and health company Abbott announced that its heart valve repair system has been approved by the US Food and Drug Administration (FDA), which is suitable for patients with potentially fatal heart disease. Abbott’s minimally invasive transcatheter TriClip repair system aims to treat tricuspid regurgitation (TR), which is a disease in which the valve between the right ventricle and the right atrium of the heart cannot be closed normally, resulting in blood reflux. Abbott has incorporated TriClip into its so-called "Fab 5" () equipment portfolio, which is expected to promote the company’s sales growth in the next few years, representing Abbott’s technological innovation and market leadership in their respective fields.

　　[financial calendar]

September 21, 2011, my hometown in Feicheng, Shandong. According to the custom in the village, on the third day after marriage, Wang Zhibao took Han Ping to the grave, saying that he wanted his new wife to visit his ancestors.

On March 15th, 2013, Wang Zhibao’s mother was hospitalized due to illness in Feicheng Hospital, Shandong Province. Hearing that his mother was unwell, Wang Zhibao hurried back by coach.

February 9, 2013, my hometown in Feicheng, Shandong. On New Year’s Eve, Wang Zhibao had a New Year’s Eve dinner with relatives and friends, while his wife looked after the crying children.

On December 18, 2015, Jinan, Shandong Province, had to go to work during the day, and Wang Zhibao and his wife followed the intermediary to see the second-hand house at night. There is no light in the top building facing the street, so they have to use their mobile phones for lighting.

　　Photographer Liu Lei recorded the life of rural youth Wang Zhibao and his wife Han Ping for seven years in this 10-square-meter rental house in a village in Jinan. From marriage, having children to their daughter’s going to school, they travel between their hometown and the city, with meager income and light sorrow … …

　　In 1986, Wang Zhibao was born in panzhuang, Feicheng City, Tai ‘an City, Shandong Province. Like other children of similar age in the village, he spent his childhood in the dirt. The experience of helping adults do farm work filled his primary school memory. He became familiar with the agricultural knowledge handed down by his ancestors and knew when to plant and when to harvest.

　　The knowledge in books is more difficult to learn than farm work, and Wang Zhibao’s academic performance is always bad. In his own words, the academic performance at that time belonged to the level of "idiot", and the teachers were too lazy to take care of him. But he is optimistic about this — — There are several other "idiots" in the same village: Er Dan in the south of the village, Yandong &hellip in the west of the village; … They naturally became good friends. Although more than ten years have passed, he can still quickly and accurately list the "idiot" students who were connected with the same life at any time, and these students, like his current state, are doing some temporary work in a city and running between the city and the countryside.

　　Wang Zhibao said that people who have never studied in their ancestors for generations seem to need genetic inheritance to read good books. Moreover, the older generation in the village always warned the younger generation that there would be no great promise in farming. Before the second day of junior high school, Wang Zhibao left the village, went to the county to be an apprentice, and began to work.

　　The hardened asphalt road in the county is smoother than the dirt road in the village. Wang Zhibao, who came to the city, felt relieved. Away from my mother’s nagging, I seem to be an independent and mature man in an instant.

　　Later, 17-year-old Wang Zhibao came to Jinan, the provincial capital. He worked as a cable worker, cleaner, hotel room cleaner and chess room attendant. At the age of 22, Wang Zhibao entered the stone renovation industry to do odd jobs, which continues to this day. Wages rose from 70 yuan at that time to 150 yuan now, and sometimes you can earn 200 yuan one lucky day, but you have to wait for the foreman’s phone call to recruit.

　　After some ignorant and failed contacts, he met his wife Han Ping through a friend’s introduction. She came to work in Jinan from Heze rural area with a low education level, but she has a good personality, which can tolerate Wang Zhibao’s natural rebellious temper and does not dislike his meager income. Wang Zhibao also feels that Han Ping is "the kind of person who lives a down-to-earth life". At the end of 2005, Han Ping moved into a 10-square-meter hut he rented near Xishilihe Street in Jinan.

　　In 2011, Wang Zhibao married Han Ping back to his hometown of Feicheng panzhuang. Han Ping was four months pregnant when she stood at the wedding scene in a wedding dress. In order to make up enough months for the unit to pay medical insurance for itself, Han Ping insisted on going to work normally in the shopping mall with a big belly. Wang Zhibao said that this can get maternity leave wages, plus maternity insurance can earn a lot of money.

　　The cost of Jinan hospital is large, and the cost of caesarean section alone is more than 8 thousand yuan, as well as nutrition and other expenses. It’s far from home. If relatives come to take care of Han Ping, their food, drink and accommodation will be another expense, so Wang Zhibao took his wife to his hometown hospital with relatively poor conditions to give birth.

　　In 2012, my daughter fell to the ground. The fortune teller said that his daughter, LMNT, had little soil. After calling many people for advice, he added the word "Yu" to her name.

　　Wang Zhibao’s family of three has rented a 10-square-meter cabin in the village of Jinan, and the house price in the nearby community doubled in 2017 compared with that in 2013. Wang Zhibao had the idea of buying a second-hand house. At the end of 2015, at the instigation of his younger brother, he took a fancy to a street-facing old-top building with an area of 40 square meters and a selling price of 280,000 yuan. After calculation, they still feel that they can’t stand the pressure of paying a down payment of 80,000 yuan and a monthly loan of more than 1,000 yuan, and finally give up. But in just one year, the price of the same type of house has risen to about 400,000 yuan.

　　Without their own house, there is no shortage of happiness in the life of a family of three. The small home is full of her daughter’s snacks and toys, with her paintings and awards on the walls, and photos of a family of three. The aisle at the door was neatly covered with Han Ping’s laundry. On weekends, Wang Zhibao will take his wife and daughter to the park to play. Seeing his daughter running with other children, he wanted to lie on the lawn and have a good sleep.

　　Wang Zhibao said that he likes the freedom and vastness of the city, but his mother who is alone in his hometown is deeply concerned. My father died 10 years ago, and my 70-year-old mother is in poor health, but it is difficult to adapt to the life in the city. He and his younger brother, who also work in Jinan, had to take turns to visit.

　　The villagers said that their family is a real person. Wang Zhibao looks forward to working in the city every day, and works sincerely. Even if his income is meager, his worries drift lightly, and he turns back and forth between his hometown and rented house, year after year. Their daughter will go to primary school next year. According to Jinan’s policy, migrant children must meet the condition that both parents pay social security for one year. There is nothing wrong with Han Ping’s social security. However, Wang Zhibao worked in Jinan for 15 years, but never paid social security … …

　　I don’t know how his sorrow fell this time.

　　"Low carbon" is one of the hottest words at the two sessions this year. CPPCC members’ proposals are piled up with "low carbon", and NPC deputies discuss "low carbon" hotly, and group discussions are also inseparable from the topic of "low carbon". "Low carbon" has become the "new favorite" that people pay attention to for a time. So, what is "low carbon" and what does agriculture and rural areas do in developing low carbon? The insights of the deputies explain the "low carbon" of agricultural and rural development from different angles.

　　The meaning of the transformation of agricultural development mode

　　"Low-carbon agriculture is first of all an idea and a development direction of agricultural transformation development mode. The essence of the low-carbon concept is to save energy. " Shang Xunwu, member of Chinese People’s Political Consultative Conference and deputy director of Gansu Agriculture and Animal Husbandry Department, said.

　　Zhang Quanguo, member of Chinese People’s Political Consultative Conference and dean of the School of Mechanical and Electrical Engineering of Henan Agricultural University, further explained low-carbon agriculture. He said: "Agriculture, as the basic industry of the national economy, is one of the main sources of greenhouse gases, and it is also increasingly affected by the greenhouse effect. How to formulate low-carbon agricultural development policies and reduce carbon emissions in agricultural production has increasingly become the focus of attention from all walks of life and one of the key areas to be considered in regional economic development. It is imperative to change the agricultural production mode as soon as possible and develop low-carbon and high-efficiency agriculture. "

　　At present, in China’s agricultural production mode, some production habits do not meet the requirements of low carbon, which is neither economical nor polluting the environment. Taking fertilization as an example, Meng Tieying, deputy stationmaster of soil and fertilizer station in Xincheng County, Guangxi Province, said that because there is a lot of local rain, heavy rain usually causes farmland to be flooded. Traditional fertilization methods make the loss of fertilizer very serious, which not only increases the cost, but also pollutes the environment. Farmers urgently need a fertilizer that can control the release rate. Data show that the low utilization rate of chemical fertilizers in China is the main reason for environmental pollution caused by chemical fertilizers. In addition to crop absorption and utilization and soil residue, more than 50% of nitrogen is not absorbed by crops and lost to farmland, which has caused a series of environmental and food safety problems, such as eutrophication of water, soil hardening, greenhouse effect and degradation of agricultural products quality.

　　Zhang put forward a proposal to develop low-carbon agriculture. He believed that it is necessary to cultivate the management concept of low-carbon agriculture, vigorously promote the innovation of agricultural production system, implement the management assessment responsibility system for energy saving and emission reduction in agriculture-related production, and gradually develop and improve agricultural energy efficiency standards from the height of national laws and regulations. He also proposed that we should pay attention to the research on low-carbon agriculture, including the integrated application research of carbon emission reduction and carbon sink expansion technologies such as energy, environment, building structure, water supply and drainage, and green space.

　　Science and technology support low carbonization of agricultural production

　　Shang Xunwu said that there are many articles that can be done to develop modern agriculture and realize the development of agriculture from extensive to refined. It can be said that in the agricultural field, it is very feasible to achieve low carbon.

　　He said that many aspects of agriculture can consider how to achieve low carbon. For example, he said that from the perspective of agricultural inputs, such as water resources, agriculture consumes a lot of water, but now the way of using water is unreasonable, causing great waste. Water is used for irrigation, but also consumes electricity. If water is saved, irrigation energy is saved, and it is low-carbon.

　　Zhang Quanguo gave a concept of low-carbon agriculture. "Low-carbon agriculture is a modern agricultural development model. Through various means such as technological innovation, institutional innovation, industrial transformation, and new energy development and utilization, energy consumption and carbon emissions are reduced as much as possible to achieve a win-win situation for agricultural production development and ecological environment protection." He further explained that low-carbon agriculture is the further development of eco-agriculture and green agriculture, which not only advocates less use of chemical fertilizers and pesticides and efficient agricultural production like eco-agriculture, but also pays more attention to the reduction of overall agricultural energy consumption and carbon emissions in the process of planting, transportation and processing, when the use of energy such as electricity, oil and gas is increasing.

　　Shang Xunwu gave his own suggestions on how to promote low-carbon agriculture. First, strengthen the role of technology and promote low-carbon technology in agriculture. The second is the innovation of production mode. For example, intensive production, through cooperatives and professional associations to promote centralized production and management, improve efficiency.

　　Zhang Quanguo also holds the same view: supporting the sustainable development of agriculture by improving the technical content of low-carbon agriculture.

　　Taking the scientific and technological development of fertilizer research and development as an example, China has supported the low-carbon fertilization in fertilizer technology research and development. Liu Jianwen, a representative from Agricultural Economics Center of Agriculture Bureau of Linshu County, Shandong Province, said that in recent years, fertilizer enterprises in Linshu have achieved remarkable results in research and development, production and popularization of slow-release fertilizers in low carbon. For example, he said that hundreds of slow-release fertilizer products developed and promoted by Jin Zhengda Group, the largest production base of slow-release fertilizers in Asia, are suitable for field crops in China. Xu Weigang, deputy director of Wheat Research Center of Henan Academy of Agricultural Sciences, summed up the advantages of slow-release fertilizers in low carbon: slow-release fertilizers can control nutrient release according to crop nutrient demand, which changes the shortcomings that fertilizers can not meet the different demands of crops at different growth stages because of rapid dissolution and nutrient loss, and can greatly improve the utilization rate of fertilizers, protect the environment, save energy, simplify crop production technology and help farmers reduce costs and increase income.

　　For supporting the development of low-carbon agriculture with science and technology, Zhang put forward more specific suggestions. He suggested: First, improve the low-carbon agricultural infrastructure in the core grain producing areas. Intensify integration, focusing on the construction of modern facility agriculture demonstration parks, ecological animal husbandry, grain (leafy vegetables) functional areas and other projects to lay a good foundation for accelerating the development of modern agriculture. Second, strengthen the cultivation of excellent varieties adapted to low-carbon environment. At the same time, we should vigorously promote the innovation of farming system and promote a number of development models such as stable grain and high efficiency, farming-pastoral cycle, and paddy-upland rotation. Third, greatly reduce the use of chemical fertilizers and pesticides, and reduce the carbon content in agricultural development. Such as using manure, compost or organic fertilizer instead of chemical fertilizer, and increasing soil nutrients through returning straw to the field.

　　The era of low-carbon rural life is coming.

　　Low-carbon mode not only has great achievements in agricultural production, but also the conditions for developing low-carbon in rural areas are ripe. Zhang Quanguo said that to develop low-carbon agriculture, it is necessary to develop new energy sources in rural areas and realize the diversification of rural energy consumption structure. Such as comprehensive utilization of straw, livestock manure, solar energy and other renewable energy resources to meet the needs of rural domestic cooking energy, rural domestic electricity and domestic hot water.

　　Twenty years ago, Tengtou Village, Ningbo City, Zhejiang Province, which wrote environmental protection into the villagers’ convention and established the only village-level environmental resources protection committee at that time, was the forerunner of rural low-carbon. Fu Qiping, the general secretary of the village party branch, said that building a "low-carbon" ecological village was the golden key to rural development. "To develop a’ low-carbon’ economy and achieve harmony between man and the natural environment, rural areas should also shoulder the burden." Fu Qiping believes that the future "low-carbon" life is a high-quality, healthy and civilized lifestyle.

　　"A large number of solar cookers in the western rural areas will greatly reduce greenhouse gases such as carbon dioxide produced by burning firewood (grass, wood), gas and coal." Ren Qixing, member of Chinese People’s Political Consultative Conference and deputy director of the Population, Resources and Environment Committee, said. He said that the western region of China has a long sunshine time and relatively rich solar energy resources, which is most suitable for popularizing solar cookers in large quantities. Ren Qixing suggested establishing financial support policies and giving appropriate financial subsidies to the purchase of solar cookers in rural areas. At the same time, vigorously support solar cooker manufacturers, give tax incentives, and help enterprises improve output, quality and scientific and technological content to meet the needs of promoting the use of solar cookers in rural areas.

　　Coincidently with Ren Qixing, Hao Yuan, member of Chinese People’s Political Consultative Conference, vice governor of Gansu Province and chairman of the Provincial Federation of Industry and Commerce, is also very concerned about the utilization of solar energy. He put forward the Proposal of Implementing the Solar Energy "South Wall Plan" at the two sessions. Its core idea is to use the south facade of the building facing the sun, including the heat collection wall, air collector and additional sunshine room on the south facade, to convert the collected solar radiation energy into heat energy as much as possible, and then transfer it to the room to achieve the purpose of heating and warming.

　　In order to promote a lower-carbon lifestyle in rural areas, Zhang also suggested that the development and application of biogas technology should be widely promoted, and at the same time, the agricultural and sideline residues should be fully utilized to improve the low-carbon utilization of straw. He said that China’s annual crop straw output is about 700 million tons, half of which can be used as energy, equivalent to 150 million tons of standard coal. He suggested focusing on the research and development of "trinity" complete technology and equipment for low-carbon utilization of straw. The core grain producing areas such as Henan Province are selected to carry out innovative research and demonstration application of low-carbon agricultural renewable energy and energy-saving engineering technology integration.

Yu Xueyuan reminds

A new batch of influenza vaccine

Appointment vaccination has been opened.

Hurry up before the flu peak comes.

Arrange it for the children!

(Bao, it’s time for an injection)

Recently, a new batch (2023~2024 batches) of influenza vaccine has arrived in various places one after another, and it can be vaccinated by appointment.

On September 5th, China CDC suggested in the latest Technical Guide for Influenza Vaccination in China (2023-2024):

All people who are over 6 months old and have no contraindications should be vaccinated against influenza.

The CDC believes that

"This winter and next spring, you may face the risk of interaction or co-epidemic of respiratory infectious diseases such as COVID-19 and influenza."

In this situation, it is obviously necessary to vaccinate against influenza.

Is it too early to get a flu shot? How old can the child be vaccinated? How to choose several types of vaccines? ……There are still many concerns about the flu vaccine.

The following small series has compiled 9 frequently asked questions. Parents who are concerned about influenza vaccine should not miss today’s content ~

(Note: The new vaccination guide involves some updates and adjustments, and the following contents will also be popularized according to the new guide, so you may find that some information is different from what you have learned before, so it is recommended to take the new guide as the reference standard ~)

01

The flu vaccine is in place

Call now, is it early?

Say the answer first, not early, and just right.

Research data show that the epidemic season of influenza in winter and spring in China is usually from the middle and late October to the middle and early March of the following year.

After vaccination, the immune effect will not reach its peak until one month later.

According to the new guidelines: "The antibody protection level can be maintained for at least 6 months after influenza vaccination."

Vaccination now can just cover the upcoming peak of influenza in autumn and winter and the flu season in early spring next year.

When the flu peak comes, the antibody is just at the peak level, which can play a better protective effect.

02

The most important thing to vaccinate.

Who are they?

The new guidelines give priority to the timely vaccination of key and high-risk groups, including:

· Medical personnel, including clinical rescue personnel, public health personnel, health quarantine personnel, etc.;

·Older people aged 60 and over;

· People suffering from one or more chronic diseases;

· Vulnerable people and employees in old-age care institutions, long-term care institutions, welfare homes and other crowd gathering places;

· Pregnant women;

·Children aged 6-59 months (about 5 years old);

· Family members and caregivers of infants under 6 months old;

· People in key places such as kindergartens, primary and secondary schools, and supervision places.

Influenza vaccines are self-funded vaccines, but some areas have some free policies. Take Beijing as an example:

People over the age of 60, students in primary and secondary schools and emergency support personnel for major events can be vaccinated free of charge.

You can pay attention to the vaccination policy in your area.

03

What are the types of influenza vaccine?

How many shots? How to fight?

At present, there are trivalent inactivated influenza vaccine (IIV3), tetravalent inactivated influenza vaccine (IIV4) and trivalent live attenuated vaccine (LAIV3) approved for marketing in China, which are produced and supplied by different manufacturers.

In order to facilitate understanding, you can look at this table for specific vaccine types and applicable populations:

(Adults and children can refer to this table.)

Babies under the age of 6 months are also indirectly protected through the vaccination of their mothers during pregnancy and the vaccination of their caregivers and family members against influenza.

In order to gain sustained immunity,It is recommended that children be vaccinated against influenza once a year.Because the influenza virus is easy to mutate, the composition of the vaccine will be adjusted every year according to the prevalent strains of the year.

04

3 or 4, which is better?

Trivalent influenza vaccine can prevent influenza caused by influenza A (H1N1), H3N2 and Victoria B virus, while tetravalent influenza vaccine can alsoPrevent one more Yamagata virus B.

Source: Network

Although the virus coverage of tetravalent vaccine is wider than that of trivalent vaccine, the transmission ability and antigenic pathogenicity of influenza B virus are not as strong as that of influenza A virus.Therefore, vaccination with trivalent influenza vaccine can also prevent influenza virus.

There is no need for everyone to miss the best vaccination time in order to wait for the fourth price. After all,It is the most important thing to get vaccinated and protected in time!

05

Injection or nasal spray, which is better?

Whether it is injection or nasal spray, there is not much difference in safety and effectiveness.

You should notice that the injected vaccine is "inactivated" and the nasal spray is "attenuated". The difference lies in:

● Injection of influenza vaccine is to inactivate the virus, so that the virus loses its pathogenic ability but retains its antigenicity.

● Nasal spray vaccine is to culture and purify the live influenza virus, so that its virulence is weakened, but it can stimulate the human body to produce antibodies without pathogenic ability.

For babies who are very afraid of injections or dizzy needles, the nasal spray inoculation method is more moderate. But there is no need to pursue it deliberately. Again, timely vaccination is the most important thing.

06

The child has got the flu

Do you still need vaccination?

Need.

If the child accidentally gets the flu and has not been vaccinated against it before, he still needs to be vaccinated again after the baby gets better.

Because of influenza A,There is no cross-protection between different types.For example, if you have had H1N1 before, you will still get sick if you are infected with H3N2 next time.

07

Influenza vaccine can be combined with other vaccines

At the same time?

There are two situations.

Inactivated influenza vaccine (injection):Can be inoculated in different parts at the same time with other inactivated or attenuated influenza vaccines.

Attenuated vaccine (nasal spray):Can not be vaccinated with another attenuated vaccine at the same time, at least 4 weeks between them.

Can it be vaccinated at the same time as COVID-19 vaccine?

Over the age of 18, you can get inactivated influenza vaccine and COVID-19 vaccine at the same time;

Under the age of 18, it is recommended that the vaccination interval be greater than 14 days.

08

Taboos for influenza vaccination

Can egg allergy be vaccinated after all?

Egg allergy can be vaccinated against influenza.

People’s Republic of China (PRC) Pharmacopoeia (2010 edition, 2015 edition and 2020 edition) does not take people who are allergic to eggs as a taboo for vaccination.

The real vaccination taboos are the following!

You can’t get any flu vaccine.

(1) Those who are allergic to any ingredients contained in the vaccine (including auxiliary materials, formaldehyde, cracking agents and antibiotics) or have a history of severe allergic reaction to any kind of influenza vaccination.

(2) Patients suffering from acute diseases, severe chronic diseases or acute attacks of chronic diseases and fever are advised to be vaccinated after recovery or stable control.

(3) Guillain-Barre syndrome occurred within 6 weeks after previous influenza vaccination, which needs to be evaluated by a doctor.

Can’t be vaccinated with nasal spray attenuated influenza vaccine.

(1) Persons with low immune function due to drug use, HIV infection and other reasons.

(2) Children and adolescents treated with drugs containing aspirin or salicylic acid for a long time.

(3) Children with asthma aged 2-4 years.

(4) Have a history of Guillain-Barre syndrome.

(5) antiviral drugs such as oseltamivir and zanamivir were used 48 hours before inoculation, or palamivir was used 5 days before inoculation, or balosha was used 17 days before inoculation.

(6) In case of severe nasal congestion, it is suggested to suspend the inoculation of attenuated vaccine by nasal spray.

(7) Children with cochlear implants should avoid using nasal spray attenuated vaccine one week before and two weeks after operation.

(8) Pregnant women

There are still many contraindications for nasal spray attenuated vaccine.ofBefore choosing to vaccinate your child, you must pay attention to the above situation.

09

After vaccination

Will you still get the flu?

Maybe.

No vaccine can prevent the disease 100%, but vaccination can reduce the risk of infection andGreatly reduce the risk of serious illness and death.

According to the research data mentioned in the new guide, when influenza and COVID-19 are co-epidemic, after vaccination,At least it can achieve more than 70% protection effect.

Therefore, if no contraindications are involved, it is recommended to vaccinate in time, especially for the elderly and children.

Even if you are vaccinated against influenza, everyone should pay attention to prevention and maintain good hygiene habits.

Wash your hands frequently, ventilate frequently, go to crowded places less, wear masks when going to crowded places, and cover your nose and mouth when sneezing.

If you don’t know where to get a vaccine, you can refer to the following ways:

(1) Gaode or 114 inquires the telephone number of local hospitals, communities and epidemic prevention stations, and makes a phone call to consult about seedlings;

(2) Pay attention to WeChat official account, a local hospital, community and epidemic prevention station, and check whether there is an entrance for online seedling appointment;

（3）微信内搜索【疫苗服务预约】，选择所在城市，根据分类预约。

另外，育学园旗下北京弘和妇产医院也可约苗，在北京的朋友想了解可以拨打电话咨询??

咨询电话：(010)6549 1911

对流感疫苗还有其他问题，可以评论留言，小编会积极给大家解答~

最后，记得戳戳【在看】，和小编一起提醒大家，该！打！疫！苗！啦！

参考资料:

[1]中国疾病预防控制中心《中国流感疫苗预防接种技术指南（2023-2024）》

[2]上海疾控《流感疫苗可以安排了，给身体留出足够时间做准备》

[3]北京日报

免责声明：本文内容更新于2023年。文章仅提供一般的医疗、健康、用药、养育等方面的科普信息，不能代替任何个人的医学诊断和治疗。个人的医疗、用药问题请咨询医生。

授权转载：原创内容，欢迎转发，转载请留言。

01

这个孩子抹上脸的东西，可能导致性早熟！家里有的赶紧扔！

02

挨骂也要说，这种油别再吃了，家里有的赶紧扔！

03

扩散！这种家电每天都在释放「大量致癌物」！赶快提醒家里人

阅读原文」，下载育学园APP

Albinism is a kind of hereditary leukoplakia caused by melanin deficiency or synthesis disorder of skin and accessory organs due to tyrosinase deficiency or functional decline.

According to clinical manifestations, albinism can be divided into three categories: ocular albinism (OA), ocular skin albinism (OCA) and albinism-related syndrome, among which ocular skin albinism (OCA) is the most common and albinism-related syndrome is the rarest.

This paper mainly expounds the clinical manifestations, genetic causes and genetic counseling of OA and OCA.

Clinical manifestations of OA and OCA

Only the eye pigment in OA patients is reduced or lacking, while the eye, skin and hair in OCA patients are obviously reduced or lacking.

1, eye performance

① Iris transillumination defect (TID)-91% ~ 100% albino patients have TID.

② nystagmus

③ Fundus hypopigmentation —— It is caused by the decrease of retinal pigment epithelium and/or choroidal pigmentation, which often leads to obvious choroidal vessels in the posterior pole. It is reported that more than 94% patients with albinism have fundus hypopigmentation.

④ hypoplasia of fovea-characterized by the continuation of the inner layer of retina behind fovea and the decrease of cone photoreceptor specialization.

⑤ optic nerve abnormality

⑥ ametropia

2. Skin manifestations

The skin and hair color of albino patients may change with age.

① Skin and hair pigmentation score

Skin and hair pigmentation scores help to objectively determine the influence of hypopigmentation.

② Skin diseases

Including all albinos, regardless of skin color, the risk of ultraviolet (UV) light-related skin diseases will increase. The most important of these is skin cancer, which includes squamous cell carcinoma, basal cell carcinoma, melanoma and less common Merkel cell carcinoma.

Genetic causes of OA and OCA

The following table summarizes the genes known to be related to nonsyndromic OCA and OA. All nonsyndromic OCA are inherited by autosomal recessive mode. OA (always non-syndrome) is inherited in an x-linked manner.

The following table summarizes the genes known to be related to OCA syndrome:

Genetic counseling

1. Inheritance mode

Nonsyndromic ocular skin albinism (OCA) caused by pathogenic variation in TYR, OCA2, SLC45A2, SLC24A5, LRMDA (C10orf11) or DCT (TYRP1) is inherited in autosomal recessive way.

Ocular albinism (OA) caused by pathogenic variation in GPR143(OA1) is inherited by X linkage.

If an individual suffers from a specific syndrome related to OCA (such as Hermansky-Pudlak syndrome or Chediak-Higashi syndrome), genetic counseling is needed for this disease.

2. Autosomal recessive inheritance-risk to family members

Parents of the proband:

The parents of the affected children are presumed to be heterozygotes causing the pathogenic variation of OCA.

If molecular diagnosis has been established in the proband, it is suggested that the parents of the proband should be tested for molecular genes to confirm that both parents are heterozygotes causing the pathogenic variation of OCA and allow reliable recurrence risk assessment.

If the pathogenic variation is detected only in one parent, and the parental identity test has confirmed biological motherhood and parent-child relationship, one of the pathogenic variations identified in the proband may occur as a newborn event in the proband or as a zygote in the mosaic parent. If the proband seems to have homozygous pathogenic variation (that is, the same two pathogenic variations), other possibilities to be considered include:

The deletion of single exon or multiple exons in the proband was not detected by sequence analysis, which led to artificial homozygosity;

Parental chromosomes and single parent homomorphism of pathogenic variation lead to homozygosity of pathogenic variation among proband.

Heterozygotes (carriers) are asymptomatic and have no risk of developing the disease.

Siblings of the proband:

If it is known that both parents are heterozygotes of pathogenic variants that cause OCA, each sibling of the affected individual has a 25% chance of being affected at conception, a 50% chance of becoming asymptomatic carriers, and a 25% chance of inheriting any familial pathogenic variants.

Heterozygotes (carriers) are asymptomatic and have no risk of developing the disease.

Descendants of the proband:

The offspring of autosomal recessive OCA individuals are obligate heterozygotes (carriers) that cause the pathogenic variation of OCA.

Other family members:

Every brother and sister of the proband’s parents has a 50% risk of becoming the carrier of OCA’s pathogenic variation.

Carrier detection:

It is necessary to identify the pathogenic variation that causes OCA in the family in advance for carrier detection of at-risk relatives.

3. X-linked inheritance-risk to family members

Parents of male proband:

The father of the affected man will not suffer from this disease, nor will he be a hemizygote of the pathogenic variant GPR143; Therefore, he does not need further evaluation/testing.

In a family with more than one affected individual, the mother of the affected male is an obligate heterozygote. Note: If a woman has more than one affected child and no other affected relatives, and if family pathogenic variation cannot be detected in her white blood cell DNA, she is likely to have germline chimera.

If the male is the only affected family member (i.e., a simple case), the mother may be heterozygote, the affected male may have new pathogenic variation (in this case, the mother is not heterozygote), or the mother may have somatic/germline chimera.

It is suggested that the mother should be tested for molecular genes to confirm her genetic status and make a reliable recurrence risk assessment.

Brothers and sisters of male proband:

The risk of siblings depends on the mother’s genetic status:

If the proband’s mother has the pathogenic variation of GPR143, the chance of transmission in each pregnancy is 50%.

Men with genetic disease variation will be affected;

The female with genetic pathogenic variation will be heterozygote (i.e. carrier). Heterozygotes are usually unaffected, although they can show iris penetration defects, "mud splash" fundus appearance and fovea hypoplasia.

If the proband represents a simplex case and the pathogenic variation cannot be detected in the mother’s leukocyte DNA, it is assumed that the risk of sibs is low, but the risk is higher than that of the general population because of the possibility of maternal lineage mosaic.

Descendants of male proband:

The affected men spread the disease-causing mutation of GPR143 to all their daughters, but not to their sons.

Other family members:

Menstruation and maternal cousins of the male proband may be at risk of GPR143.

Note: Molecular genetic testing may be able to identify family members with new pathogenic mutations, and this information can help determine the genetic risk status of large families.

Heterozygote detection:

To identify female heterozygotes, it is necessary to identify the pathogenic variation of GPR143 in the family in advance.

Note: As carriers of this X-linked disease, women are heterozygotes, which are usually not affected, but they may show iris penetration defects, "mud splash" fundus appearance and fovea hypoplasia.

Source | Metz Medical official website

Write | ｜Anna.An

Original title: Inheritance and Manifestation of Albinism

Read the original text