Related news:　　　From May 1st, the ban on overseas cartoons will be extended by one hour.　　　　

　　　　CCTV.com News: The news broadcast of Guizhou People’s Broadcasting Station ignored the orders of the State Administration of Radio, Film and Television (SARFT), wantonly played up sexual life, sexual experience, sexual experience and sexual organs in several sets of radio programs, and boasted about the function of sexual drugs. Today, it was severely criticized by SARFT, and the illegal programs were stopped and cancelled.

　　　　According to the website of the State Administration of Radio, Film and Television, on September 13, 2007, Guizhou People’s Broadcasting Station broadcasted sexual obscenity and indecent programs on urban and economic frequencies, which was explicitly stopped by the State Administration of Radio, Film and Television. On November 12th, 2007, Guizhou People’s Broadcasting Station changed the name of Jin Tao’s Talk about Sex, which was stopped, to Jin Tao’s Night Talk, and was ordered by the State Administration of Radio, Film and Television to investigate and deal with it again. Since mid-January, 2008, when the whole province of Guizhou is united in fighting against the snowstorm and freezing disaster, the news broadcast of Guizhou People’s Broadcasting Station has continued to broadcast obscene and obscene programs that exaggerate sexual life, sexual experience, sexual experience, sexual organs and sexual medicine functions in the programs of Health Special Line and Healthy World. The informed criticism issued by the State Administration of Radio, Film and Television to Guizhou People’s Broadcasting Station was copied to the CPC Guizhou Provincial Committee and the Guizhou Provincial People’s Government.

　　　　The State Administration of Radio, Film and Television (SARFT) pointed out that since September 2007, radio, film and television administrative departments at all levels in China and radio and television broadcasters have conscientiously implemented the spirit of the Central Committee, and in accordance with the unified arrangements of SARFT, seriously rectified and severely investigated pornographic and obscene programs, and achieved remarkable results, which were fully affirmed by the Central Committee and praised by the broad masses. The fact that Guizhou People’s Broadcasting Station refuses to implement the provisions of the State Administration of Radio, Film and Television, and its programs involving sexual obscenity and obscenity are repeatedly banned fully shows that Guizhou People’s Broadcasting Station is indifferent in orientation and position awareness, lax in political discipline and propaganda discipline, lacking due social responsibility and professional quality, lax in rules and regulations, and weak in propaganda management, which must be dealt with seriously.

　　　　The State Administration of Radio, Film and Television severely criticized Guizhou People’s Broadcasting Station and its principal responsible persons, and informed the whole country.

　　　　The State Administration of Radio, Film and Television ordered the Guizhou Provincial Radio and Television Bureau to immediately stop broadcasting and cancel the sexually obscene and obscene programs such as Health Line and Healthy World of Guizhou People’s Broadcasting Station, seriously rectify Guizhou People’s Broadcasting Station, severely investigate and deal with relevant personnel and persons in charge of Guizhou People’s Broadcasting Station and news broadcasting in strict accordance with relevant regulations, and report the investigation to the State Administration of Radio, Film and Television as soon as possible.

　　　　The State Administration of Radio, Film and Television requires that all provincial, district (city) radio, film and television bureaus should be duty-bound, strictly implement the relevant publicity management regulations of the State Administration of Radio, Film and Television, earnestly perform their publicity management duties, and once again conduct a comprehensive and thorough clean-up and inspection of radio and television broadcasters within their jurisdiction, especially those at prefecture (city) and county levels. It is necessary to take measures to check at all levels, implement responsibilities, and not neglect their duties, perfunctory, and whitewash. To strengthen the work of listening and watching, strict supervision and management, to prevent the resurgence of pornographic programs, and in March 10, 2008, the clean-up inspection will be reported to the State Administration of Radio, Film and Television. The administrative departments of radio, film and television at all levels and radio and television broadcasters should conscientiously organize study, convey and implement the spirit of a series of documents issued by the State Administration of Radio, Film and Television on the thorough rectification of pornographic and obscene programs, strengthen the sense of orientation and position, emphasize social responsibility and post responsibility, improve the censorship system and broadcasting system, be serious about political discipline and propaganda discipline, increase supervision and investigation, and resolutely ban them to ensure the correct orientation of radio and television propaganda.

　　　　The State Administration of Radio, Film and Television emphasizes that radio, film and television administrative departments at all levels and radio and television broadcasters should thoroughly implement the spirit of the 17th Party Congress, vigorously publicize the socialist core value system, adhere to the orientation of advanced socialist culture, firmly grasp the correct direction of public opinion, keep in mind the social responsibility of radio and television, resolutely safeguard the good image of radio and television, always put social benefits first, advocate the concept of harmony, cultivate the spirit of harmony and build a harmonious culture.

　　　　The State Administration of Radio, Film and Television (SARFT) said that it would continue to supervise and inspect the rectification of pornographic and obscene radio and television programs in various places. Anyone who refuses to implement the provisions of the General Administration will be found together and investigated together, and the mechanism of punishment, accountability and withdrawal of radio and television broadcasters will be started in accordance with relevant regulations. At the same time, the audience is welcome to report, and the telephone number of illegal programs of the State Administration of Radio, Film and Television is 010-86095315; The online reporting address is http://www.chinasarft.gov.cn/.　

Editor: Feng Ye

　　CCTV News:Under the background of complicated and changeable international trade environment and slow recovery of international investment, although some enterprises have moved their manufacturing bases from China to lower-cost areas, more investors are optimistic about the future development of China market.

　　In the process of moving towards the high end of the global value chain, where should China enterprises compete in the value chain? From "Made in China" to "Made in China", what efforts should be made? A number of business representatives discussed these issues in the column "On Tao".

　　Pang Guanglian, Secretary-General of China Petroleum and Chemical Industry International Capacity Cooperation Enterprise Alliance: In the process of this value chain reconstruction, some China enterprises have moved to Southeast Asia due to the increase of this cost, but recently we were in Zhejiang, and I recently visited more than 40 enterprises in Zhejiang. Many Zhejiang enterprises went to Vietnam and Cambodia, and after investing, they came back two years later, because China is the most complete among all industrial categories stipulated by the United Nations, with supporting infrastructure and industry.

　　You Feifeng, Chairman of Huafeng New Materials Company: From a long-term perspective, if we carry out some industrial transfer, it must be considered by some comprehensive factors, which is called comprehensive cost in our industry. Although it is said that low-end industries will inevitably move to some areas with lower comprehensive costs, some high-end industries may still develop further in some industries under the influence of such factors as being close to resources and some markets.

　　Pang Guanglian: But we must also see a trend now. The production focus of our entire petrochemical products has indeed shifted from west to east. Now China has occupied 39.4% of the world’s chemical production, which is close to 40%. According to BASF’s new CEO, it is possible that by 2030, the total output value of China’s chemical industry will occupy half of the whole world, and then a major change will take place.

　　Another is the focus of production, which gradually concentrates on the supply places of raw material production resources. In recent years, the flammable oil and gas in the United States has risen rapidly. As Mr. kadouri said yesterday, the total investment in the petrochemical industry in the United States in recent years has reached 230 billion US dollars, which is an amazing data. Many China enterprises, including those present here, are now choosing to invest in the Middle East, so now the whole world market is inseparable. You have me and I have you. Whether we let foreign-funded enterprises enter China or China enterprises go abroad, Chinese and foreign enterprises will cooperate with each other. This is the way to be king in the future.

　　You Feifeng: In the development of Huafeng for many years, it also relies on the introduction of some technologies from BASF and Kostron in China and the investment from their factories in China, which has provided us with some very stable help in the supply of raw materials for upstream resources.

　　In this process, Huafeng has sold some of our own products to BASF and Costron through years of development and some breakthroughs in its own products. Therefore, in the layout of the whole industrial chain, everyone is in a very high degree of cooperation and a state of common development and sharing development with all parties in the upstream and downstream of the industrial chain.

　　Lei Huanli, President of Kostron China: I think we are very happy from Kostron or myself, that is to say, we will continue to open wider to the outside world.

　　Second, I said that this openness is an ideological openness. This ideological openness is how to make these partners in each value chain stronger. We should do our duty as local residents or citizens. That responsibility means that we have some good practices and practices that we can learn from. We are willing to discuss with all partners in the value chain. This concept, which goes back to our company, is sustainable development. We should pay enough attention to the respect of resources, because resources are owned by everyone, shared by all and the earth, and we can’t squander them at will.

　　If we can work together and do this thing well together, I think it will be very, very good As a multinational company, we are deeply involved in this market. When we regard ourselves as a local market, we actually have this responsibility. We are also willing to fulfill this obligation and do this with our partners or with the government.

　　Yu Feng, Chairman of Honeywell China: Because Honeywell itself is a company with a sales volume of US$ 40 billion and a market value of more than US$ 100 billion, it has a large business in the world. We have some experience in so many businesses, and we also have many lessons, experiences and lessons to tell us. If an enterprise wants to be sustainable in a market, it must make use of its own advantages and the advantages of local partners, so win-win cooperation is the long-term direction in the future.

　　Second, there is another important method, that is, innovation. No matter how the value chain changes in the future, we must have our own original technology and depth. We must firmly believe that only depth will make this enterprise have a high level. Innovation costs money, and innovation needs lasting investment.

　　Therefore, my third suggestion must be management. We have some original inventions in the world ten years ago, and the market share in China is zero. Why? It’s not that the technology is bad, but that the price is too high and the cost is too high. Our cost is higher than the price that our customers in China can accept. So what should we do? Through management, these technologies have been localized and cooperated with local suppliers, and the cost has been greatly reduced. Therefore, these technologies have experienced triple-digit growth in China in the past few years. Therefore, as management requires efficiency, after improving efficiency, it will be fed back to our research and development and our innovation.

　　CCTV News:Lantern Festival is a day of family reunion. From the northwest wind area of the motherland to the moving train, from the railway workers who stick to their posts to the passengers on the journey, people experience different reunions on the same Lantern Festival.

　　This two-year-old boy named "Sambo" is the son of Zhang Wei and Pei Liyuan, employees of Hami Power Supply Section. Because Pei Liyuan works in the 13-room station in Bailifeng District, 170 kilometers away, the family gathers less and leaves more. This Lantern Festival, Zhang Wei will take his son to the 13 rooms for a different Lantern Festival.

　　Triratna: "this is for mom."

　　Knowing that he was going to find his mother, Xiao Sanbao was very excited. After more than three hours of running, the train arrived at the thirteen-room station.

　　Triratna: "rush! Mom, mom! "

　　The sudden appearance of her son surprised Pei Liyuan. The thirteen rooms where Pei Liyuan works are a fifth-class station on the Lanzhou-Xinjiang Railway and the core area of the Bailifeng District, where strong winds are raging all the year round. At the end of 2011, the whole line of Lanzhou-Xinjiang Railway was electrified, and once the foreign objects were blown into the catenary by strong wind, it would affect the safety punctuality of Lanzhou-Xinjiang Railway. Pei Liyuan’s job is to monitor and analyze the catenary data to ensure the safety and smoothness of this electrified railway artery. It’s common to have a gale of more than ten in the spring wind zone. Pei Liyuan hasn’t been home for more than ten days. This time, Zhang Wei specially brought her favorite "black sesame stuffing" dumplings.

　　Zhang Wei, who doesn’t know how to be romantic on weekdays, also wants to express his love to his wife on the Lantern Festival.

　　Pei LiyuanAfter so many years of marriage, I feel that he didn’t take the initiative to buy me a gift.

　　Calling "I didn’t expect it", there are also passengers on this local train from Baoji, Shaanxi to Pingliang, Gansu. A group of teenagers with an average age of only ten years old came to the train to have a Lantern Festival, which brought surprises to the passengers.

　　In the carriage, this group of social fire teenagers with an average age of only ten years old painted various facial expressions and dressed in folk social fire costumes, playing with knives and guns in an exemplary manner, attracting more and more tourists. On the passenger train from Heze to Harbin, the solve riddles on the lanterns race carefully prepared by the train staff of Jinan Passenger Transport Section was in full swing.

　　Train conductor Wang Zhanyu: "Long ears, short tail, only eating vegetables, not eating, what is this?"

　　Child traveler: "Little Rabbit."

　　Train conductor Wang Zhanyu"By the way, I’ll give you a little gift. Happy Lantern Festival."

　　Passenger Mr. Wang: "I guessed three correctly. I was so happy to meet this Lantern Festival event in the car for the first time."

　　After guessing the riddles, the dining car staff served the steaming Lantern Festival for the passengers to taste.

　　Enjoy the journey and enjoy the Lantern Festival, yeah!

　　CCTV News:Neihuang County, Anyang City, Henan Province, is a traditional agricultural county in the northern plain of Henan Province. Since 2009, Neihuang County has invested in a large-scale ceramic industry and introduced a number of ceramic enterprises, which has brought about a ceramic industrial park with an annual output value of more than 10 billion yuan. Business is booming and the industry is booming, which is a good thing, but the local people have been calling the media to complain about the pollution caused by the ceramic industrial park in the village recently, and the people are complaining.

　　UAV shoots ceramic industrial park at an altitude of 200 meters.

　　On March 12, 2018, the reporter came to Neihuang County, Henan Province. In order to verify whether there was any pollution problem in the local ceramic industrial park, the reporter used a drone to shoot the ceramic industrial park in Neihuang County at an altitude of 200 meters. As far as the eye can see, there are many factories and bare white powder piled up everywhere. Neihuang Ceramic Industrial Park is the largest ceramic production base and product distribution center in the Central Plains. The industrial park is divided into two parts, one is the production area and the other is the sales area. Although the production enterprises have not started, the business of large and small ceramic tile sales stores is still very prosperous. Sales staff told us that most of the tiles sold by these stores came from the production enterprises in the park. During the conversation, the reporter hoped to know whether ceramic tile production would pollute the environment. Unexpectedly, the salesperson answered directly.

　　Sales staff of ceramic industrial park in Neihuang County, Henan Province: "The pollution is not small, because there is no way to eat groundwater now. When the country stops production, our side stops during the day and produces at night."

　　The surrounding area of the ceramic park looks like a fire scene from afar.

　　In order to find out the truth, the reporter conducted an investigation in and around Neihuang County Ceramic Industrial Park for several days. Finally, on the evening of March 20th, the reporter smelled a strong and pungent smell around the ceramic park, which was suffocating. The company named "Langer Ceramics Co., Ltd." emitted huge smoke. Even in the night, the smoke was extremely amazing, thick and thick, looking from a distance, like a fire scene, and the air was filled with the choking smell of kerosene.

　　Sewage forms a colorful oil stain on the river.

　　The Xiaohe River is the only river in Neihuang County. On the morning of March 21st, the reporter noticed that the "white" sewage was continuously discharged into the river through a drain. These discharged "white water" have foam on the surface and an unpleasant smell. These are the two outlets under the Xiaohe Bridge, and the sewage has formed a colorful oil stain on the river. We walked along the section of the Nitrate River passing through the ceramic park and found that there were seven similar outlets in total. Some villagers who work in the ceramic factory told reporters that the wastewater generated in the ceramic production process will first be discharged into the sewage pool of the factory, and then slowly seep into the ground. Every rainy day, we will "take the opportunity" to discharge it into the nitrate river next to the ceramic park along the rainwater pipeline.

　　Pollution causes crops to fail to collect groundwater.

　　What impact does the pollution caused by ceramic enterprises have on local people? The reporter saw in an interview with Xiaotun Village, the nearest village to the west side of the ceramic industrial park, that the villagers told us about their experiences one after another. Near the ceramic industrial park, the wheat began to turn yellow.

　　Local villagers: "The wheat is too small to be obvious, the pepper is obvious, the fruit is on top, and the wheat is wrapped in a shell. It was obvious as soon as the ceramic factory started. The smoke it emits is glazed in the factory, and the corn is covered with white powder, which is the same as frost. It doesn’t bear ears, and red peppers don’t bear peppers. "

　　The crops in the fields near the ceramic factory are almost never harvested.

　　The villagers told reporters that in recent years, almost all the crops in the fields near the ceramic factory have been harvested every autumn. In the eyes of the villagers, the "culprit" that caused the grain harvest was the "smoke" coming out of the chimney of the ceramic factory. Besides air pollution, the local people are more afraid of the water discharged from the ceramic factory. In the village of Dadikou, which is just across the river from the ceramic park. The groundwater in the village has been polluted, and the water quality of the well water, which was originally clear and bright, has become worse and worse, and it can only be used for washing clothes or feeding animals. As a last resort, the villagers can only go far and near, and dig wells from other villages dozens of miles away. In this villager’s home, he specially pumped a bucket of water from his well more than 30 meters deep.

　　The groundwater is dirty, and there are oily floating objects on the water surface.

　　In order to prove to the reporter that the pollution he suffered was absolutely true, the villager deliberately burned a pot of hot water. Just after heating, the reporter found that a layer of floating objects like oil stains appeared on the water surface, and a lot of scale appeared at the bottom. During the investigation, the reporter visited several villages around the ceramic industrial park. The dirty groundwater can be seen everywhere, and the groundwater in Xizhangbao Village, located on the east side of the ceramic industrial park, has also been seriously polluted. The staff of Guardian Ceramics Co., Ltd. admitted that there was water pollution in the park.

　　Ceramic factories issue "pollution fees" according to the distance.

　　In addition, during the interview, the villagers all mentioned a "pollution fee" issued by the ceramic factory. They told reporters that according to the distance between each field and the ceramic factory, the ceramic factory subsidizes the expenses ranging from 20 yuan to 100 yuan per mu.

　　Reducing cost to avoid "coal to gas" sewage treatment is not up to standard

　　In fact, the environmental protection department has clearly stipulated the emission limits of pollutants such as sulfur dioxide, nitrogen oxides and particulate matter in ceramic industrial enterprises. Then, have the production enterprises in Neihuang County Ceramic Industrial Park strictly implemented the emission standards of pollutants in ceramic industry and installed environmental protection facilities such as desulfurization, denitrification and dust removal?

　　salesman: "One of our factories, the smallest one, has to use 300 to 400 tons of coal. If it is a big factory, it has to reach the concept of 500 to 800 tons. Air pollution, smog and desulfurization will not work, and it will also exceed the standard. You can desulfurize during the day, and I’m still discharging at night. This thing, there is no way, if you want to reduce costs, you can only do this. "

　　Cost-reducing enterprises steal sewage at night

　　The salesperson who claimed to be Neihuang Jiade Ceramics Co., Ltd. told the reporter that in order to reduce costs, enterprises can only use night smuggling. However, if clean energy natural gas is used, it is relatively easier to meet the requirements in the standard, but it will inevitably lead to an increase in the cost of tiles. According to insiders’ calculation, if "changing coal into gas" is implemented in Neihuang production area, the production cost of ceramic enterprises will increase by 18%, and the cost of a tile will increase by 50 cents. For cost reasons, up to now, there are still many ceramic enterprises in Neihuang Ceramic Park that have not changed from coal to gas.

　　Besides the potential waste gas pollution, how do the ceramic factories in Neihuang Ceramic Industrial Park treat their production wastewater? This is a report in Henan Daily in 2016, which clearly reads: "The sewage treatment project in the south of Neihuang City, with an investment of 28 million yuan, can treat 5,000 tons of sewage every day, which can basically meet the sewage treatment needs of ceramic parks. While promoting the transformation and upgrading of the ceramic industry, the project has also achieved both economic and environmental benefits." Two years have passed, has this sewage treatment project with an investment of 28 million yuan been completed, and is it treating industrial wastewater generated by ceramic factories? With all kinds of questions, the reporter came to Bishuiyuan Sewage Treatment Plant in Neihuang Ceramic Park.

　　The staff of several sewage treatment plants told reporters that this sewage treatment plant was put into operation in the second half of 2017. Due to the limitations of the process, it was only responsible for treating the domestic sewage in the ceramic factory. As for where the industrial wastewater generated by the ceramic factory went, they did not know.

　　Functional departments shirk environmental pollution and lack supervision

　　The reporter learned in the Neihuang County Water Affairs Bureau that in the Neihuang County Ceramic Industrial Park, the drain that the reporter saw was not built by government departments, but was built privately. The staff of the Neihuang County Water Affairs Bureau also suggested that the reporter report to the Environmental Protection Office of the Ceramic Park. According to the address provided by the staff of the Water Affairs Bureau, the reporter found the "Zhongyuan Porcelain Capital Environmental Protection Institute".

　　As soon as I entered the door, the reporter thought I was in the wrong place, and the environmental inspection department was located in the marketing hall of the ceramic production enterprise. As an environmental volunteer, the reporter met the person in charge of "Zhongyuan Porcelain Capital Environmental Protection Institute". In the face of a reporter’s question, the person in charge of Zhongyuan Porcelain Capital Environmental Protection Institute told the reporter that the responsibility of Zhongyuan Porcelain Capital Environmental Protection Institute is to check the sewage discharge and air pollution of production enterprises, but when the reporter reported that the enterprise had secretly discharged sewage and secretly built sewage outlets to discharge industrial wastewater directly into the river as an environmental volunteer, the person in charge said that they were "unaware" of the number of sewage outlets under the Xiaohe Bridge and the pollution situation. Neihuang county monitors the groundwater around the ceramic park every year, and has never found any pollution problems. In the face of such an answer, the reporter suggested that it was less than one kilometer from the enterprise to the "Zhongyuan Porcelain Capital Environmental Protection Institute", hoping to take environmental inspectors to check it on the spot, but I didn’t expect it to be rejected by the staff of the Environmental Protection Institute.

　　During the interview, the villagers told reporters that since nearly 90% of the laborers around the ceramic factory are working in the factory, on the one hand, they are polluted hometown, and on the other hand, they are worried about the future, and more are helpless.

　　villager: "Ceramic factory has certain advantages and disadvantages. The advantage is that there is a place to work and earn money, so you don’t have to go out, especially for women. The downside is that the pollution is too strong. "

　　On the one hand, it is a polluted environment, and on the other hand, it is an important source of local tax revenue. Which is more important? This is indeed a multiple-choice question before the local people and the local government. However, a good ecological environment is the fundamental foundation for the sustainable development of people and society. I hope the local government can do this multiple-choice question well, and don’t destroy the homes of future generations for the sake of immediate achievements and immediate interests.

During the Spring Festival holiday in 2025, the number of traffic trips exceeded 2.3 billion.

On the 5th, the reporter learned from the 2025 Spring Festival travel rush Comprehensive Transportation Work Class that during the Spring Festival holiday this year (from January 28th to February 4th), the cross-regional personnel flow of the whole society was 2,306.845 million.

Specifically, the passenger traffic by railway is 96.26 million, the passenger flow by road is 2,182.93 million (the passenger travel by non-operating passenger cars on expressways and provincial highways is 1,989.65 million, and the passenger traffic by road is 193.28 million), the passenger traffic by waterway is 9.413 million, and the passenger traffic by civil aviation is 18.2415 million.

Guo Liang was an early proletarian revolutionary of our party, a famous leader of the workers’ movement, and a close comrade-in-arms who organized and led the workers’ movement with Mao Zedong. Mao Zedong praised him as "a famous organizer of the workers’ movement". On March 29th, 1928, Guo Liang was secretly killed by Kuomintang reactionaries in Qianping, Simenkou, Changsha, at the age of 27. In Guo Liang’s short life, although there are not many poems left behind, they show Shi Ce’s unyielding heart and courage to fight.

"Ask the society, what is the truth?"

Guo Liang, formerly known as Guo Jing Jia, was born in 1901 in Wenjiaba, Sheshan, Tongguan Town, Wangcheng County, Hunan Province (now Guo Liang Village, Tongguan Street). At the age of 11, he changed his name to Guo Liang, hoping to be as resourceful as Zhuge Liang. When Guo Liang was a teenager, he paid close attention to the poor life of the people who were hungry and toiling, and thought deeply about it. He wrote a sharp new-style poem "Ask the Society": A strange question is not worth mentioning by scholars and juren, and it is also common sense for teachers, but they know nothing about it! Where did the Gu Mi of the rich come from? Why do farmers carry grain into the rich man’s barn? Ask the society, what is the truth? Where did the rich man’s house come from? Why do poor people build houses and rich people live in peace? Ask the society, what is the truth? Where do the clothes of the rich come from? Why don’t people who grow cotton and weave clothes cover their bodies? Ask the society, what is the truth? People live in the same world, why are the rich and the poor different? Ask the society, what is the truth? This poem tells the people’s sufferings in plain language and lashes out at social injustice in extremely sharp language, which is particularly easy to resonate and soon spread.

It is also in order to answer these doubts in Ask the Society that Guo Liang read more and more historical books, cared about his family and country, and began to explore the truth actively. In the autumn of 1915, 14-year-old Guo Liang was admitted to Changjun Middle School. With the anti-Japanese patriotic struggle of Hunan people constantly emerging, Guo Liang participated in the patriotic anti-Japanese struggle of Changsha students. In 1916, Guo Liang saw the heads of the murdered revolutionaries on the streets of Changsha, and angrily chanted poems: "How much blood and tears are there?"? Revenge needs to pour water into the cave, and patriotism can’t be afraid of hanging its head! " Grief and indignation gushed out from this poem, and the patriotic fire took root in the young man’s heart.

"A trickle of water sinks into a huge stream"

Once the patriotic fire is lit, it burns in Guo Liang’s young chest. He sympathized with the sufferings of the people and helped the poor to destroy their homes. In the process of dealing with the masses, I also deeply felt the turbulent but confused revolutionary enthusiasm. It seems that Guo Liang, who is surrounded by mountains and mountains, is eager to explore the way of struggle and the direction of progress. In 1919, Mao Zedong founded Xiangjiang Review in Changsha to spread and introduce new ideas. Guo Liang, who has been trying hard to explore the road of saving the country and the people, was struck by Mao Zedong’s article and soon became a loyal reader of Xiangjiang Review. In 1920, Guo Liang was admitted to Hunan No.1 Normal University, and met Mao Zedong by chance. From then on, he often asked Mao Zedong for advice on how to reform the society. Introduced by Mao Zedong, Guo Liang joined Xinmin Society, and then participated in Hunan Marxist Research Association organized by Mao Zedong, He Shuheng and Fang Weixia. In the practice of struggle, Guo Liang began to have a clear revolutionary ideal and struggle ideas, and firmly believed that nothing could be done without transforming the country.

In the winter of 1921, introduced by Mao Zedong, Guo Liang joined the Communist Party of China (CPC) and became one of the earliest party member in Hunan. When joining the party, Guo Liang made a generous statement: "Some people just give an empty mouth, and I, Guo Liang, are willing to give my head to the party." Guo Liang, who joined the Communist Party of China (CPC), finally belonged, and wrote a poem to express his feelings: "A trickle of water sinks into a huge stream, and it turns around without stopping; The back waves push the front waves and fly over the mountains to be free. " He compared his personal strength to a trickle, which, once put into the arms of the Party organization, converged into stormy waves and condensed into a majestic force of revolutionary struggle under the guidance of party flag.

"When will I wash away all my worries?"

After gloriously joining the Party, Guo Liang became more and more mature in thought, and more and more deeply realized that only by mobilizing millions of working people to work together can the action of saving the country have a steady stream of power. In the summer of 1922, after graduating from Hunan No.1 Normal School, Guo Liang immediately joined the revolutionary movement. In August of the same year, appointed by Mao Zedong, Guo Liang went to Yuezhou to carry out the work of Guangdong-Han railway labor movement. When he sailed down the Xiangjiang River to Dongting Lake, he was full of thoughts and couldn’t help chanting, "Xiao Shui, Xiang Shui, flows into the Yangtze River without a head." Long Jun sent me Dongting water, when will I wash away all my worries? " Guo Liang knew that the trip was bumpy and arduous, but he had no time to think about the severity of the difficulties, but immediately devoted himself to the fiery labor movement. On September 9th, Guo Liang organized and led a strike of 3,000 workers on the Guangdong-Han Railway, which shocked the whole country and opened the prelude to the first labor movement climax in Hunan. At the end of the same year, Guo Liang led the kindling of the workers’ movement to his hometown Tongguan. In the struggle, Guo Liang made good use of concise language to complain about the sufferings of ceramic workers, such as: "Digging clay bent his waist, pushing clay bowed his back, burning kiln goods burned his heart, making kiln goods worn his hand, and selling kiln goods lost his leg." In a few words, the injustice of the poor life of ceramic workers for generations was revealed, which aroused the workers’ resonance, condensed the struggle force, led the ceramic workers to resist the so-called "kiln door tax" and organized the establishment of the Tongguan ceramic trade union. On the day when the Tongguan Ceramics Trade Union was established, the Hunan District Committee of the Communist Party of China sent a pun couplet. The first part is "Don’t say that loose sand can’t make a great instrument", and the second part is "You should know that soil can turn into gold".Highly praised Guo Liang for leading generate, a ceramic worker.

In leading the Guangdong-Han railway workers’ strike, the pottery workers’ struggle against taxes and taxes, and the Changsha workers’ struggle against imperialism and feudal warlords, Guo Liang has increasingly demonstrated his ability to approach and inspire the masses. At that time, Bolshevik, the central theoretical publication, commented on Guo Liang: Guo Liang was the pioneer of Hunan workers’ movement. Anyuan in Jiangxi, Shuikoushan in Hunan, Changsha, Guangdong, Han and Zhuping in Hunan, Hubei and Jiangxi provinces, these local workers and other industrial professional workers all organized struggles under his direct and indirect guidance.

"Heroes have never bowed their heads since ancient times."

"Xiang water stirs up the hatred of the river, and the sword breaks the water and flows more. Although good and evil are reversed, heroes have never bowed their heads since ancient times. " This poem was sung by Guo Liang on the way to Wuchang after he was arrested by the enemy. It not only expressed his resentment of "the inversion of good and evil", but also showed his heroic spirit of being fearless and dying. In July, 1924, after Guo Liang was elected as the chairman of Hunan Anti-Imperialism Alliance, he wrote a lot of campaign articles. Under the careful organization of Guo Liang, Hunan once again set off an anti-imperialist climax. Guo Liang, who was at the forefront of the struggle, was wanted several times by Zhao Hengti, the warlord of Hunan at that time. In the face of the wanted notice, Guo Liang laughed it off without fear, and wrote a doggerel: "Zhao thief is persistent, a man looks like a wolf, killing with one hand and burning incense with the other, shouting autonomy and secretly communicating with the powers. If this cub is not removed, the people will suffer, and they will get a dog’s head and a pair of copper coins. Advise the police, don’t be fooled, help the tiger eat, and it will come to no good end. The notice is integrated, so remember to be detailed. " This limerick exposes the ugly face of reactionaries in laughing and cursing, and also points out the direction of struggle for the people in plain language. Under the leadership of Guo Liang and other comrades, anti-imperialist and patriotic activities in Hunan have become increasingly frequent and powerful. Facing the great revolutionary situation, Guo Liang and his comrade-in-arms Xia Minghan touched the scene and recited poems. Guo Liang recited: "One sword hangs on the bedside, and the GREAT GHOST kid comes in." Xia Minghan replied, "Kill all demons and level the world, and the mountains, rivers, the sun and the moon will be rearranged." The two revolutionary heroes expressed their aspirations with poems, and their determination to fight to the end jumped to the page.

In January 1928, dispatched by the CPC Central Committee, Guo Liang served as the secretary of the special committee of Hunan, Hubei and Jiangxi. Under the leadership of his organization, the party organizations in the border areas of Hunan, Hubei and Jiangxi provinces have been restored and developed. On March 27th, Guo Liang was arrested in Yueyang because of a traitor’s informer, and was executed secretly by the reactionary authorities in the early morning of 29th. Before his execution, he wrote a cone-shaped suicide note to his wife, who is also a native of communist party: "Can Ying, my love: Bright running around, homeless and stateless. I’m done. Hope to be kind and caress my son to follow my ambition. This is awkward. " This touching suicide note not only expresses deep attachment to family members, but also expresses infinite expectations for future generations to continue their struggle.

　　On October 26th, an exclusive interview with DRIs was held in Beijing.

　　Yang Yuexin, Chairman of China DRIs Revision Expert Committee and Chairman of China Nutrition Society, Ma Aiguo, Deputy Chairman of the Revision Committee and Executive Vice Chairman of China Nutrition Society, Ding Gangqiang, Deputy Chairman of the Revision Committee, Secretary of the Party Committee of China Nutrition Society and Director of the Institute of Nutrition and Health of China CDC, Yang Xiaoguang, Vice Chairman of China Nutrition Society and researcher of the Institute of Nutrition and Health of China Center for Disease Control and Prevention, Peng Xianwu, the supporting unit of DRIs revision and general manager of Amway (China) Science and Technology Innovation Center, attended the interview and interpreted the new revision.

　　Yang Yuexin introduced that the 2023 edition of China DRIs is the ninth edition. The revised expert committee and technical working group composed of nearly 100 nutrition experts lasted for three years. Based on the four basic principles of scientificity, advancement, integrity and continuity, the different reference intakes of 20 age groups including energy, nutrients and other dietary ingredients and pregnant women and lactating mothers totaled more than 70 nutrients and other dietary ingredients, which were revised and confirmed, and were held at the 14th Asian Nutrition Conference in September 2023.

　　The revision of DRIs in 2023 mainly includes four aspects. First, the concepts and procedures have been improved and perfected. Different procedures for determining different reference values of nutrients have been newly formulated, and the technical points of each link of the formulation procedures have been uniformly determined. The concepts and connotations of recommended intake and specific recommended values for reducing the risk of diet-related non-communicable diseases have been further clarified and improved. Secondly, the basic reference values of China population were formulated and revised, including age grouping, representative weight, reference value of breast milk composition, recommended weight gain of pregnant women, PAL of physical activity level, etc. Thirdly, the new research results of nutrients and other dietary components in the past decade at home and abroad in the fields of function, evaluation, requirement, safety and prevention of chronic diseases have been included, and more research results targeting China residents have been included. Fourth, from the writing framework, format and other styles, it highlights the positioning of reference books centered on quantitative values.

　　Peng Xianwu believes that this revision has far-reaching guiding significance for the big health industry, such as the data of newly added plant nutrients such as coenzyme Q10 and Lycium barbarum polysaccharide, and the quantification of nutrients such as proanthocyanidins, which will help Amway and industry to develop products and guide consumers to use them.

　　Peng Xianwu introduced that in 2022, Amway and China Nutrition Society established Nutrilite Special Fund for Plant Functional Components and Health Research, aiming at attracting more research institutions and personnel to participate in the research direction of plant nutrients, opening up production, learning and research, transforming research results into products faster, and making more scientific research results benefit the public.

　　This revision has greatly changed the protein intake of the elderly and the calcium supplement standard for adults. Yang Xiaoguang believes that China has entered an aging society, and the elderly and ordinary people can’t meet the demand for protein, which is easy to lead to sarcopenia. Therefore, it is necessary to improve the dietary structure of the elderly and increase the intake of protein. Yang Xiaoguang introduced: "The 2023 edition of DRIs revised the requirement of protein for the elderly aged 65 and above in China, and its recommended intake increased from 0.98 g/(kg day) to 1.17 g/(kg day), which is an important achievement".

　　Ding Gangqiang said that in recent years, the health awareness of Chinese residents has been continuously strengthened, and dietary nutrition and healthy behaviors have been continuously formed, but chronic diseases related to nutrition are still increasing. It is hoped that the release of the 2023 edition of DRIs will further guide the needs of China residents in all aspects of dietary nutrition, especially how to achieve a reasonable and balanced diet, and complete the objectives of the second largest action of Healthy China Action-Reasonable Diet Action.

　　The revision of DRIs has a wide range of significance and value. First, it has scientific value, which determines the types and quantities of nutrients that each person should consume every day qualitatively and quantitatively. Second, social value is an important basic data support for formulating relevant policies, regulations and standards; The third is the value of technical support, which plays an important guiding role in the dietary design and evaluation of collective feeding units such as schools and nursing homes, the nutrition labeling of prepackaged foods, and the product research and development of food enterprises.

Southeast Network is the official news portal of Fujian, which is headed by the Propaganda Department of Fujian Provincial Committee of the Communist Party of China and sponsored by Fujian Daily Newspaper Group.

recent days

Website of the State Administration of Market Supervision

Announce the latest batch

Motor vehicle recall information

Involving Guangqi Honda and Dongfeng Honda

Land Rover, Mercedes-Benz, Volvo, etc.

↓↓↓

Guangqi Honda Automobile Co., Ltd.

Dongfeng Honda automobile co., ltd

Recall some domestic hybrid electric vehicles

Recently, Guangqi Honda Automobile Co., Ltd. and Dongfeng Honda Automobile Co., Ltd. filed a recall plan with the State Administration of Market Supervision according to the requirements of the Regulations on the Management of Defective Automobile Product Recall and the Implementation Measures for the Regulations on the Management of Defective Automobile Product Recall, and decided to recall the following vehicles from now on.

I Guangqi Honda Automobile Co., Ltd.

A total of 87,092 domestic hybrid BREEZE and plug-in hybrid BREEZE cars produced between January 4, 2019 and December 29, 2022 were recalled.

Second, Dongfeng Honda Automobile Co., Ltd.

A total of 169,000 domestic hybrid cars (CR-V) and plug-in hybrid cars (CR-V) produced between June 8, 2017 and August 17, 2022 were recalled.

For the vehicles within the scope of this recall, due to the layout problem of the battery positive wiring harness, when the left front part of the front of the car collides at a specific angle, the battery positive wiring harness may be damaged, and there is a risk of short circuit and fire.

Guangqi Honda Automobile Co., Ltd. and Dongfeng Honda Automobile Co., Ltd. will replace the improved battery positive wire harness for vehicles within the recall range free of charge to eliminate potential safety hazards.

Guangqi Honda Automobile Co., Ltd. and Dongfeng Honda Automobile Co., Ltd. will notify the relevant users of the recall by registered mail, and take the initiative to contact the users through authorized special sales service stores to make an appointment to arrange the recall and maintenance. Users of Guangqi Honda can call the service hotlines: 800-830-8999 (fixed-line users only), 400-830-8999 and the hotlines of special sales service stores for consultation, or visit Guangqi Honda’s website for recall information. Users of Dongfeng Honda can call the service hotlines: 800-880-9899 and 400-880-6622 (by mobile phone) for consultation, or visit the website of Dongfeng Honda for recall information. In addition, you can also visit the website www.dpac.org.cn for more information and reflect the defect clues.

Jaguar Land Rover (China) has limited investment.

The company recalled some imports.

Land Rover Range Rover Sport Series Cars

A few days ago, Jaguar Land Rover (China) Investment Co., Ltd. filed a recall plan with the State Administration of Market Supervision according to the requirements of the Regulations on the Management of Defective Automobile Product Recall and the Measures for the Implementation of the Regulations on the Management of Defective Automobile Product Recall. From March 29th, 2024, some imported 2023 Land Rover Range Rover Sport cars produced from July 4th, 2022 to November 30th, 2022 were recalled, totaling 1,987 vehicles.

Due to the factory assembly, the right taillight of the vehicles within the scope of this recall may get water and fail during use, which can not provide effective signals for the rear vehicles, increasing the risk of vehicle collision and posing potential safety hazards.

Jaguar Land Rover (China) Investment Co., Ltd. will replace the taillights on the right side of the tailgate and the right side of the car body for vehicles within the recall range free of charge to eliminate potential safety hazards.

Jaguar Land Rover (China) Investment Co., Ltd. will notify relevant users of this recall by registered mail. Users can call the Land Rover brand customer service hotline: 400-820-0187 through landline or mobile phone for consultation. In addition, you can also visit the website www.dpac.org.cn for more information and reflect the defect clues.

Mercedes-Benz (China)

Automobile sales co., ltd. recalled

Some imported GLE SUV cars

A few days ago, Mercedes-Benz (China) Automobile Sales Co., Ltd. filed a recall plan with the State Administration of Market Supervision according to the requirements of the Regulations on the Management of Defective Automobile Product Recall and the Measures for the Implementation of the Regulations on the Management of Defective Automobile Product Recall. From now on, a total of 118 imported GLE SUV vehicles with production dates from February 9, 2021 to November 18, 2021 will be recalled.

Some vehicles within the scope of this recall are not properly fixed with the grounding fixing bolts of the 12V battery grounding wire, resulting in an increase in the resistance of the fixed area and a large current passing through it, which may lead to an abnormal temperature rise in this area and a fire risk.

Mercedes-Benz (China) Automobile Sales Co., Ltd. will inspect and retighten the grounding wire fixing bolts for vehicles within the recalled scope free of charge through Mercedes-Benz authorized dealers, and replace the grounding wire if it is damaged, so as to eliminate potential safety hazards.

Mercedes-Benz (China) Automobile Sales Co., Ltd. will notify the relevant owners of the recall by registered mail. Users can call the service hotline: 400-818-1188 through landline or mobile phone for consultation (service time is 24 hours a day from Monday to Sunday). In addition, you can also visit the website www.dpac.org.cn for more information and reflect the defect clues.

Volvo automobile sales (Shanghai)

Co., ltd. recalled some imports

XC90 automobile

A few days ago, Volvo Car Sales (Shanghai) Co., Ltd. filed a recall plan with the State Administration of Market Supervision according to the requirements of the Regulations on the Management of Defective Automobile Product Recall and the Measures for the Implementation of the Regulations on the Management of Defective Automobile Product Recall. It is decided to recall some imported XC90 cars from 2015 to 2024, which were produced between December 1, 2014 and September 23, 2023, with a total of 1,200 vehicles.

The fixing bolts of the seat belts in the second row of some vehicles within the scope of this recall are not tightened according to the regulations. When a vehicle collides, the fixing bolts of the seat belts may be loose, which will affect the restraint effect of the seat belts, increase the risk of passengers being injured, and pose potential safety hazards.

Volvo Car Sales (Shanghai) Co., Ltd. will tighten the seat belt fixing bolts according to the specified torque for the vehicles within the recall range free of charge through authorized dealers of Volvo Cars to eliminate potential safety hazards.

Volvo Car Sales (Shanghai) Co., Ltd. will notify relevant users by registered mail. Authorized dealers of Volvo Cars will also take the initiative to contact the relevant car owners to arrange the recall. Users can call the Volvo car after-sales service hotline: 10108666 for consultation through mobile phones and fixed telephones. In addition, you can also visit the website www.dpac.org.cn for more information and reflect the defect clues.

China Heavy Duty Truck Group Jinan Truck Co., Ltd.

Recall part of limited company

Haowo brand traction car

Recently, China National Heavy Duty Truck Group Jinan Truck Co., Ltd. filed a recall plan with the State Administration of Market Supervision according to the requirements of the Regulations on the Management of Defective Automobile Product Recall and the Implementation Measures for the Regulations on the Management of Defective Automobile Product Recall. It is decided to recall some Hauwo brand traction vehicles produced from April 23, 2020 to November 29, 2020, totaling 37 vehicles.

Due to manufacturing problems, the rear position lights on both sides of the top of the cab were not installed in the vehicles within the scope of this recall. At night or under poor road lighting conditions, the outline of the vehicle may not be displayed, which may pose a safety hazard.

China National Heavy Duty Truck Group Jinan Truck Co., Ltd. will replenish the rear position light assemblies on both sides of the rear top of the cab free of charge for vehicles within the scope of recall, so as to eliminate potential safety hazards.

This recall was carried out under the condition that the State Administration of Market Supervision initiated a defect investigation. Affected by the investigation, China National Heavy Duty Truck Group Jinan Truck Co., Ltd. decided to take recall measures to eliminate potential safety hazards.

China National Heavy Duty Truck Group Jinan Truck Co., Ltd. will notify relevant users by registered mail or telephone through dealers, and arrange for free recall and maintenance. Users can also call the 24-hour service hotline: 4001888666 for consultation. In addition, you can also visit the website www.dpac.org.cn for more information and reflect the defect clues.

Original title: "A large number of recalls! Check yourself quickly! Your family may also have it.

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　　[Aika Auto Domestic New Car Original]

　　On September 17th, 2023, Geely Automobile officially announced the prices of two new models of the Star Yue L in Xi ‘an Black Light Factory, namely the Yun Qi version with a guide price of 157,700 yuan and the Skyline version with a guide price of 168,700 yuan. As new models, Yun Qi version and Skyline version have added exclusive design on the basis of Star Yue L, and are equipped with the latest vehicle system of Galaxy OS 2.0. While announcing the selling price, Geely Automobile also announced the car purchase courtesy including financial gift, rejuvenation gift, quality gift, maintenance gift and flow gift. At the same time, Geely Automobile also announced that it will push the Galaxy OS 2.0 car system for all old users OTA of Xingyue L for free.

　　The exclusive designs for these two models include the far-Dai matte gray car paint and the ink-splashing environment-friendly suede interior. Among them, the official guide price of Yuandai frosted gray car paint is 6,000 yuan, and the official guide price of splash-ink environment-friendly suede interior is 3,000 yuan, while the Sky Edition will come standard with splash-ink environment-friendly suede interior. The environment-friendly chamois interior is covered with a large area of environment-friendly chamois. The covering rate of the seat surface is 68.8%, the ceiling is 100%, and the door panel and instrument panel are all covered with chamois. Not only has the touch been improved, but the sense of advanced has also been filled. In addition, the Galaxy OS 2.0 car system has a brand-new UI design, which is more fashionable and beautiful. The voice wake-up speed reaches millisecond level, and the whole scene can be seen. At the same time, a custom desktop that is more in line with the operating habits of the mobile terminal is adopted to create a more intelligent and non-inductive interactive experience for users.

　　A quick look at the highlights of new cars

　　·　Newly added exclusive designs, including Yuan Dai matte gray car paint and splash-ink environment-friendly suede interior.

　　·　Equipped with the latest Galaxy OS 2.0 car system.

　　·　2.0T+8AT

　　New car introduction

　　In terms of appearance, Geely Xingyue L adopts the family-style design language of Geely Automobile 4.0 generation products, and continues to maintain the high value of atmospheric dynamics. In terms of details, the front face of Xingyue L adopts the iconic straight waterfall air intake grille, and the black middle net is decorated with chrome trim, which makes the front face look very delicate and dynamic. The headlight with full LED light source energy matrix is very sharp in shape, and the two-stage design is highly recognizable. A chrome-plated decorative strip is added to the front enclosure that runs through the design, which is perfectly integrated with the L-shaped chrome-plated decorative strips on both sides.

　　Viewed from the side, Xingyue L adopts a muscular line design, which, together with the burly body size, makes the side look very atmospheric. In terms of body size, the L length/width/height of Xingyue is 4770*1895*1689mm, and the wheelbase is 2845 mm.. The rear of the car continues the family’s atmospheric and steady design style. The biggest highlight is the adoption of the popular through taillights, and the interior adopts the "aurora dot matrix" design, which is full of scientific and technological sense.

　　As for the interior, Xingyue L has adopted a brand-new design concept of "Symphony of Time and Space", and all designs have demonstrated the people-oriented design idea. High-grade suede fabric is widely used in the interior, and the exquisite pearl stitching is used. With the special suede seat with the ultimate skin-friendly touch, the exquisite, elegant and unique car interior is created for the vehicle. In addition, three large 12.3-inch screens are also a highlight of the interior. The 12.3-inch central control screen uses Qualcomm Snapdragon 8155 chip, while the 12.3-inch screen in front of the driver integrates rich functions such as watching videos, listening to songs, games, Tik Tok and karaoke.

　　In the power part, the two new models are equipped with the high-power version of the Drive-E series 2.0TD engine, with a maximum power of 175kW(238 HP) and a peak torque of 350Nm. The transmission is equipped with the 8AT gearbox from Aisin.

　　Editor’s point of view: Up to today, the cumulative sales volume of China Star Series has exceeded 730,000 vehicles, among which the cumulative sales volume of Xingyue L has exceeded 300,000 vehicles, with an average monthly sales volume of over 10,000 vehicles. It is worth mentioning that in August, the sales volume was 17,169 vehicles, with the monthly sales exceeding 15,000 vehicles for three consecutive months. In the past five months, the sales volume of high-equipped 8AT products accounted for over 65%. The addition of the two new models not only brings a more exclusive design, but also brings a richer choice of models for consumers who are concerned about Xingyue L.

　　Wonderful content review:

　　The release of Geely Panda Knight is expected to be launched in early September.

　　Geely Panda mini "Asian Games Bear" has been listed for 29,900 times.

　　Geely Panda mini is officially listed at a price of 39,900 yuan.

Foreword

Influenza virus can cause seasonal influenza, and may even cause a pandemic outbreak. Influenza virus is a negative-strand RNA virus with complex classification, numerous subtypes and easy mutation. At present, it is recognized that the best way to prevent influenza is vaccination. In order to ensure the effectiveness of the vaccine, the World Health Organization (WHO) updates the composition of the vaccine strain every year.

Changes of influenza vaccine strains in the northern hemisphere in 2024-2025

In order to keep the vaccine effective, it is necessary to update the components of influenza virus vaccine regularly. After analyzing the global influenza virus epidemiology, etiology and vaccine serology, WHO announced the recommendation of influenza vaccine components in the northern hemisphere from 2024 to 2025 on February 23, 2024.

?

Trivalent chicken embryo culture vaccine

an A/Victoria/4897/2022 (H1N1)pdm09-like virus

an A/Thailand/8/2022 (H3N2) -like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Trivalent cell culture or recombinant protein vaccine

an A/Wisconsin/67/2022 (H1N1)pdm09-like virus

an A/Massachusetts/18/2022 (H3N2)-like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Tetravalent chicken embryo and cell culture or recombinant protein vaccine

The following components are added on the basis of trivalent vaccine

a B/Phuket/3073/2013 (B/Yamagata lineage)-like virus

Since March 2020, the naturally occurring B/Yamagata virus has not been confirmed. WHO thinks that it is not necessary to use B/Yamagata virus as a component of influenza vaccine, and it should be removed from the component of influenza vaccine. Where tetravalent vaccine is still used, the composition of B/Yamagata line is consistent with the previous recommendation.

Comparing the composition of influenza vaccine in the northern hemisphere from 2023 to 2024, it was found that the change of composition was mainly due to the difference of H3N2 virus strains:

Vaccine types

2023-2024

2024-2025

Trivalent chicken embryo culture vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Thailand/8/2022 (H3N2) -like virus

Trivalent cell culture or recombinant protein vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Massachusetts/18/2022 (H3N2)-like virus

Recombinant antigen is the key material for vaccine research.

In influenza virus-related vaccines, drugs and even diagnostic reagents, key target antigens have played an important role. In the following table, we have sorted out the information of HA, NA and NP proteins.

albumen

function

app; application

HA

(hemagglutinin)

The sialic acid receptor on the host cell membrane binds to help the virus envelope fuse with the host cell membrane; Coagulation

Basic research on influenza

Influenza vaccine research and development

Development of anti-hemagglutinin antibody

Study on virus detection reagent

NA

(neuraminidase)

Hydrolyze sialic acid receptor to promote the release of mature virus particles

Research and development of antiviral drugs

Basic research on influenza

Influenza vaccine research and development

Antibody development

Study on virus detection reagent

NP

(nuclear protein)

Combine with influenza genetic material and participate in virus gene replication, transcription and translation; Maintain the stability of virus gene

Research and development of antiviral drugs

Basic research on influenza

Antibody development

Diagnostic product development

The recombinant antigen of influenza vaccine strain can be used in all aspects of vaccine development, such as vaccine content detection, vaccine biological titer detection and toxicological experimental research. Using recombinant antigen for ELISA detection, we can analyze the levels of serum total antibody and neutralizing antibody after vaccination, and use recombinant protein as control to detect the vaccine content.

The results of detecting the serum antibody level of mice immunized with vaccine by recombinant influenza HA protein (image from Andersen, et al.)

Influenza vaccine strain-related antigens are available in stock.

Yiqiao Shenzhou continues to pay attention to the research progress of influenza vaccine, and has built a relatively complete influenza virus research reagent library. It has been online to recombine some proteins of HA, NA and NP of the northern hemisphere influenza vaccine strain in 2024-2025, and it is available from stock. Order it now!

Consultation is polite!

After checking the information correctly, you can get a 35 yuan Luckin Coffee voucher.

Scanning code to understand the recombinant antigens related to components of influenza vaccine strains from 2024 to 2025;

references

[1]https://www.who.int/publications/m/item/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season

[2] Andersen, et al. Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief.[J]. Frontiers in Immunology.2021.747032.

[3] Bangaru S , et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface[J]. Cell, 2019.

[4] Kim M, et al. Inhibition of infection virus internalization by (-)-Epigallocatechin-3-gallate. [J]. Antiviral Research, 2013,100 (2): 460-472. Continue to slide to see the next one.

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