Family reunion day, same Lantern Festival, different reunion!

  CCTV News:Lantern Festival is a day of family reunion. From the northwest wind area of the motherland to the moving train, from the railway workers who stick to their posts to the passengers on the journey, people experience different reunions on the same Lantern Festival.

  This two-year-old boy named "Sambo" is the son of Zhang Wei and Pei Liyuan, employees of Hami Power Supply Section. Because Pei Liyuan works in the 13-room station in Bailifeng District, 170 kilometers away, the family gathers less and leaves more. This Lantern Festival, Zhang Wei will take his son to the 13 rooms for a different Lantern Festival.

  Triratna: "this is for mom."

  Knowing that he was going to find his mother, Xiao Sanbao was very excited. After more than three hours of running, the train arrived at the thirteen-room station.

  Triratna: "rush! Mom, mom! "

  The sudden appearance of her son surprised Pei Liyuan. The thirteen rooms where Pei Liyuan works are a fifth-class station on the Lanzhou-Xinjiang Railway and the core area of the Bailifeng District, where strong winds are raging all the year round. At the end of 2011, the whole line of Lanzhou-Xinjiang Railway was electrified, and once the foreign objects were blown into the catenary by strong wind, it would affect the safety punctuality of Lanzhou-Xinjiang Railway. Pei Liyuan’s job is to monitor and analyze the catenary data to ensure the safety and smoothness of this electrified railway artery. It’s common to have a gale of more than ten in the spring wind zone. Pei Liyuan hasn’t been home for more than ten days. This time, Zhang Wei specially brought her favorite "black sesame stuffing" dumplings.

  Zhang Wei, who doesn’t know how to be romantic on weekdays, also wants to express his love to his wife on the Lantern Festival.

  Pei LiyuanAfter so many years of marriage, I feel that he didn’t take the initiative to buy me a gift.

  Calling "I didn’t expect it", there are also passengers on this local train from Baoji, Shaanxi to Pingliang, Gansu. A group of teenagers with an average age of only ten years old came to the train to have a Lantern Festival, which brought surprises to the passengers.

  In the carriage, this group of social fire teenagers with an average age of only ten years old painted various facial expressions and dressed in folk social fire costumes, playing with knives and guns in an exemplary manner, attracting more and more tourists. On the passenger train from Heze to Harbin, the solve riddles on the lanterns race carefully prepared by the train staff of Jinan Passenger Transport Section was in full swing.

  Train conductor Wang Zhanyu: "Long ears, short tail, only eating vegetables, not eating, what is this?"

  Child traveler: "Little Rabbit."

  Train conductor Wang Zhanyu"By the way, I’ll give you a little gift. Happy Lantern Festival."

  Passenger Mr. Wang: "I guessed three correctly. I was so happy to meet this Lantern Festival event in the car for the first time."

  After guessing the riddles, the dining car staff served the steaming Lantern Festival for the passengers to taste.

  Enjoy the journey and enjoy the Lantern Festival, yeah!

Development and innovation of China’s technology trade

Text/Wang Xiaohong, Deputy Director of Information Department of China International Economic Exchange Center; Xie Lanlan, Strategy Department of China International Economic Exchange Center; Guo Xia, postdoctoral fellow, Information Department, China International Economic Exchange Center.

Technology trade can effectively combine and utilize global advanced technologies to improve innovation efficiency and reduce the cost and risk of independent research and development. It is an important way for developing countries to realize technological innovation and industrial leapfrog development, and it also runs through the whole process of China’s opening up, independent innovation and industrial development. In the early days of the founding of New China, China established a complete industrialization system with the technology import strategy as the core. Since the reform and opening up, China has actively integrated into the global industrial chain, supply chain and innovation chain, especially through large-scale technology introduction, digestion and absorption, the innovation ability has greatly jumped, and key core technologies in some fields have been obtained, which has significantly improved the industrial competitiveness and trade competitiveness, and achieved a historic leap from a technologically backward country to a world innovation power. Technology trade has played an important role in promoting the upgrading of industrial structure, expanding enterprise technology accumulation, enhancing independent innovation ability and cultivating new economic kinetic energy, and has become a propeller and accelerator for building an innovative country. However, compared with developed countries, there is still a big gap in China’s technical level, especially in the core key technical fields, and the ability of independent innovation is relatively weak, so it is still very important to implement the technology trade strategy. At present, a new round of scientific and technological revolution and industrial revolution are changing with each passing day, and open innovation cooperation has become an inevitable trend of global technological innovation and development. Therefore, it is of great significance to continue to play the role of technology trade in promoting independent innovation, continuously improve the quality of technology introduction and expand the scale of technology export, so as to enhance technological innovation capability, promote industrial upgrading and service trade development, and thus promote high-quality economic development.

I. Characteristics and Problems of China’s Technology Trade Development since the Thirteenth Five-Year Plan

Since the "Thirteenth Five-Year Plan", China has deeply implemented the innovation-driven strategy, the technology trade has developed steadily, the structure has been continuously optimized, the scale of technology trade has continued to expand, trading partners have spread all over the world, the trade methods have become more diversified, and the market dominant position of private enterprises has been rising. However, China’s technology trade market, especially the import of core technologies, is highly dependent on developed countries, and the "shortcomings" such as small-scale export of intellectual property rights and unbalanced regional technology introduction are still outstanding.

(A) the main characteristics of China’s technology trade development since the 13th Five-Year Plan

1. Strong growth in technology exports and steady growth in imports. From 2016 to 2019, China’s technology trade volume increased from 54.228 billion US dollars to 67.338 billion US dollars, with an average annual growth rate of 7.48%, including export growth rate of 11% and import growth rate of 4.63%. In 2019, the scale of trade, export and import were 1.88 times, 12.58 times and 1.05 times that of 2011, respectively. Due to the rapid growth of export scale, the technology trade deficit decreased from $7.228 billion in 2016 to $3.064 billion.

2. Technology import is "softened", and intellectual property import becomes the main way. China’s technology import mode has changed from "hard" to "soft", which indicates that the "gold content" of technology import has been continuously improved. From 2017 to 2019, the proportion of China’s technology fees to technology imports was 97.44%, 97.23% and 89.30% respectively; Among them, the import of intellectual property rights (patented technology, proprietary technology and trademark license) dominated the technology import, accounting for 65.63%, 68.46% and 60.32% respectively; Followed by technical consultation and technical services, accounting for 21.05%, 16.19% and 29.07% respectively; The third is computer software, accounting for 7.24%, 10.98% and 2.27% respectively. From a practical point of view, M&A is an important route for Chinese enterprises to acquire key core technologies in recent years. In the case of long-term technology research and development, high risk, high investment and difficulties in introducing core technologies, overseas mergers and acquisitions can effectively avoid foreign technical barriers, enable enterprises to master core technologies in a short time, and form strong technical strength and innovation ability. According to the statistics of Morning Post M&A, in recent years, obtaining technical targets is the most important goal of overseas M&A of Chinese enterprises. In 2018, the overseas advanced technology mergers and acquisitions of Chinese enterprises in manufacturing, TMT (technology, media and telecommunications) and medical and health industries accounted for 15.85%, 15.65% and 10.98% respectively.

3. Technology export is mainly based on technical consultation and technical services, which is the main source of surplus in technology trade. From 2017 to 2019, the proportion of technical consulting and technical services in technology export was 68.20%, 62.85% and 69.33% respectively, followed by computer software export, accounting for 16.23%, 8.82% and 7.42% respectively. Technical consultation and technical services are the largest surplus items in technology trade, with the surplus of 8.251 billion US dollars, 12.428 billion US dollars and 12.047 billion US dollars in 2017-2019 respectively. Secondly, the export of computer software, with a surplus of $1.411 billion in 2019, shows that China’s export competitiveness is rising by undertaking international software and information technology outsourcing, especially the development of new generation information technology such as artificial intelligence, big data, mobile internet and cloud computing, which is promoting the transformation and upgrading of information technology service outsourcing enterprises, and its scale strength is constantly increasing.

4. The technology trade market is still dominated by foreign-funded enterprises, and domestic-funded enterprises are on the rise. Foreign-funded enterprises have always occupied an absolute dominant position in China’s technology trade. From 2017 to 2019, foreign-funded enterprises accounted for 69.10%, 72.02% and 53.10% of technology imports, and 70.29%, 60.53% and 58.75% of technology exports, respectively. It shows that foreign-funded enterprises are still the main support of China’s technology trade and the important driving force of technology innovation, and their technology spillover effect still has an important impact on China’s technology innovation ability. It also shows that China’s increasingly optimized business environment is attractive to foreign-funded high-tech enterprises. At the same time, the share of domestic-funded enterprises in technology trade has gradually increased, indicating that the endogenous power of China’s technology trade has been continuously enhanced. In 2019, the proportion of state-owned enterprises, collective enterprises and private enterprises in technology imports totaled 38.25%, an increase of 13.54 percentage points compared with 24.71% in 2017; The proportion in technology exports totaled 37.19%, up 12.38 percentage points from 24.81% in 2017. And in 2018, the R&D intensity of domestic-funded enterprises was 1.3%, which was 0.3 percentage points higher than that of foreign capital, indicating that the continuous improvement of innovation ability of domestic-funded enterprises led to the growth of technology exports.

It is noteworthy that private enterprises have become an important market subject of China’s technology trade after foreign-funded enterprises. From the perspective of technology import, in recent years, private enterprises have continuously increased their efforts in technology import through transnational mergers and acquisitions, purchasing patented technology, strengthening technical cooperation with foreign enterprises and institutions, etc. From 2017 to 2019, the proportion of technology import of private enterprises was 16.72%, 15.92% and 17.67% respectively, reflecting that private enterprises have achieved remarkable results in technology upgrading through technology introduction. From the perspective of technology export, private enterprises have surpassed state-owned enterprises. From 2017 to 2019, the proportion of private enterprises in technology export was 15.50%, 16.78% and 15.35% respectively. The introduction of technology has promoted private enterprises to increase R&D investment. In 2018, the full-time equivalent of R&D personnel and the internal expenditure of R&D funds in private enterprises accounted for one-third of all types of industrial enterprises in China, showing an increasingly strong ability to digest and absorb innovation and gradually narrowing the technological gap with multinational companies and state-owned enterprises.

The technology trade market is mainly concentrated in developed countries and regions, and the United States is still the largest trading partner. At present, China has established technical and trade ties with more than 130 countries around the world, but it is highly concentrated in the developed economies of the United States, Europe and Japan and remains basically stable. In 2019, the top ten sources of technology imports in China were the United States, Japan, Germany, Russia, Sweden, South Korea, Switzerland, Hong Kong, China, Taiwan, China and Italy, accounting for 87.28% of China’s technology imports, accounting for 87.28% of China’s technology imports, of which the total technology imports from the United States, Japan and Germany accounted for 56.15%. In 2019, the top ten technology export destinations were the United States, Hong Kong, China, United Arab Emirates, Japan, Germany, Sweden, Bangladesh, Singapore, South Korea and British Virgin Islands, which accounted for 71.30% of China’s technology export. The United States has always been China’s largest technology import country and export destination country. From 2017 to 2019, China’s technology imports to the United States accounted for 33.57%, 34.74% and 24.03% respectively, and its technology exports to the United States accounted for 22.22%, 30.83% and 17.62% respectively. In 2019, both bilateral technology imports and exports fell sharply due to trade friction. It is noteworthy that the "Belt and Road" has gradually become an important emerging market for China’s technology export. Among the top ten destinations of China’s technology export in 2019, the United Arab Emirates, Bangladesh and Singapore all belong to countries along the route.

It should be emphasized that the three major economies of the United States, Europe and Japan have a high degree of overlap in China’s technology import and export market. On the one hand, it shows that the technology gap between China and developed economies is narrowing, and the technology division of labor is gradually developing from vertical division of labor to horizontal division of labor. For example, the phenomenon of patent cross-licensing between China’s information technology enterprises and multinational companies in developed countries is more and more confirmed. At the same time, we should also see that the technology trade between China and developed countries is still based on comparative advantages. China mainly imports core technologies and intellectual property rights from developed countries, while exports mainly non-core technologies such as technical consulting and services, such as professional technology, software and computer services, etc., and there are obvious gaps in technological advancement and added value. For example, China is the fourth largest importer of intellectual property rights in the world. In 2018, China’s intellectual property royalties paid to the United States accounted for 1/4 of the foreign intellectual property royalties in that year, accounting for 1/6 of the US intellectual property royalties in that year. From 2011 to 2018, the royalties paid by China to the United States increased from $3.46 billion to $8.64 billion, with an average annual growth rate of 13.97%.

6. Technology import is mainly based on manufacturing industry, and technology export is mainly based on service industry. From the perspective of technology import, transportation equipment, communication equipment, computers and other electronic equipment, chemical raw materials and products, general equipment, special equipment, electrical machinery and equipment, medicine and other manufacturing industries are the main industries of China’s technology import. From 2017 to 2019, the manufacturing industry accounted for 8 seats in the top ten technology import industries, and the total import value of manufacturing technology accounted for 78.28%, 76.97% and 63.85% respectively, indicating that foreign technology is still an important source for China’s manufacturing industry to acquire advanced technology and realize technology upgrading. From the perspective of technology export, the service industry is dominant. From 2017 to 2019, the top ten technology export industries include professional technology, software, research and development, computer services and other service fields, and the total proportion of technology exports in these four fields is 51.72%, 53.68% and 53.25% respectively, indicating that service exports mainly based on international service outsourcing are the main sources of technology exports. In addition, technology exports mainly involve manufacturing fields such as communication equipment, computers and other electronic equipment, medicine, chemical raw materials and chemicals, special equipment and transportation equipment. From 2017 to 2019, the total proportion of manufacturing technology exports was 33.61%, 17.80% and 23.78%, respectively, indicating that these fields improved their innovation ability through technology import and promoted the development of technology exports.

7. Technology-based foreign investment and utilization of foreign capital develop in both directions, and the ability to comprehensively apply domestic and foreign technology markets and resources is enhanced. In terms of foreign investment, the establishment of overseas R&D institutions and science parks is an important channel for Chinese enterprises to integrate into the global innovation chain and combine global talents, technology and information through open innovation. More and more enterprises seek technical resources for transnational mergers and acquisitions or set up overseas R&D institutions to quickly master core key technologies. According to statistics, by 2017, only high-tech zone enterprises had set up 994 overseas R&D institutions. For example, setting up R&D centers and production R&D bases overseas has become an important part of the globalization strategy of Chinese automobile enterprises. In terms of utilizing foreign capital, the relaxation of China’s foreign capital market access policy and the continuous improvement of the domestic business environment have promoted the rapid growth of high-tech foreign capital. In 2019, the absorption of foreign capital in China’s high-tech service industry increased by 44.3%, of which the absorption of foreign capital in information transmission, software and information technology services, scientific research and technology services increased by 29.4% and 68.4% respectively. The R&D investment of multinational corporations in China is increasing. At present, there are more than 2,000 regional headquarters and R&D centers invested by multinational corporations in China, including more than 1,800 foreign R&D centers recognized by the state.

(B) the main problems in the development of China’s technology trade

1. The core technology is highly dependent on developed countries, which leads to frequent economic and trade frictions.

In the past two years, the United States and other developed countries have been blocking China’s technology on the grounds of intellectual property protection and safeguarding national security, and have been launching intellectual property trade frictions, especially increasing the difficulty and cost of introducing core key technologies and cutting-edge technologies into China. In the Sino-US economic and trade friction, the scope of China’s high-tech enterprises and institutions listed by the United States on the list of export control entities is constantly expanding, and at the same time, restrictive measures such as imposing tariffs on the import of high-tech products in China are strengthened. For example, a new generation of information technology, new energy vehicles, aviation products, high-speed rail equipment, high-performance medical equipment, biomedicine, new materials, agricultural machinery and equipment and industrial robots. In addition, there are more and more obstacles for Chinese enterprises to acquire high-tech enterprises in the United States. In February 2020, the United States officially came into effect two laws and regulations to reform the national security review system for foreign investment and strictly control the loss of intellectual property rights of key technologies. Japan is also considering the scope of high-tech export control, focusing on the next generation technology used in artificial intelligence and robots.

2. The export scale of intellectual property rights does not match China’s status as an innovative power.

China has become one of the largest intellectual property countries in the world. By 2019, the number of domestic invention patents was 1.862 million, and the number of invention patents per 10,000 population was 13.3. According to the statistics of the World Intellectual Property Organization (WIPO), in 2019, China has ranked first in the number of patent applications in the world for nine consecutive years, and the number of international patent applications has surpassed that of the United States for the first time, ranking first in the world. However, the situation of more peripheral patents and fewer core patents has led to the small-scale export of intellectual property rights in China, but it has to pay a high amount of intellectual property royalties. From 2017 to 2019, China’s intellectual property exports accounted for 11.56%, 15.60% and 11.35% of technology exports, while intellectual property imports accounted for 65.63%, 68.46% and 60.32% of technology imports in the same period, with trade deficits as high as $18.246 billion, $18.271 billion and $17.584 billion respectively. On the one hand, it shows that developed economies still occupy the dominant position in global technological innovation, on the other hand, it also reflects that China has not paid enough attention to the export strategy of intellectual property rights.

3. The regional distribution of technology introduction is seriously unbalanced.

There is a positive relationship between the difference of regional technology trade level and the level of economic development in China. Due to the high level of economic development in the eastern region, the advantages of high-tech industries are obvious, and technology trade also has an absolute advantage. In 2018, the proportion of technology imports in the eastern, central, western and northeastern regions was 64.53%, 8.79%, 19.40% and 7.28% respectively. The unbalanced spatial distribution of technology introduction means the gap between the eastern region and the central and western regions in terms of new technology acquisition, digestion, absorption and industrial application, which is bound to further widen the gap in technological innovation between regions, thus affecting the ability of central and western regions to undertake industrial transfer and independent innovation.

4. There is still much room for improvement in technology introduction, digestion, absorption and re-innovation of domestic enterprises.

The technology introduction of domestic enterprises has always been lower than that of foreign-funded enterprises. From 2017 to 2019, the proportion of domestic-funded enterprises ③ technology import was 30.9%, 27.98% and 46.9% respectively. This situation may bring some negative effects. For example, some foreign-funded enterprises control technology for the sake of maintaining and consolidating the competitive position in the market, and only transfer it within the company, thus reducing the technology spillover effect. At the same time, the digestion, absorption and re-innovation ability of domestic-funded enterprises is about 1 times lower than that of foreign-funded enterprises. In 2018, the average R&D investment expenditure of industrial enterprises was 3,106,100 yuan for domestic enterprises and 6,231,300 yuan for foreign-funded enterprises; The average full-time equivalent of R&D personnel is 7.04 person/year for domestic-funded enterprises and 13.42 person/year for foreign-funded enterprises. Therefore, domestic-funded enterprises should increase the intensity of technology introduction, and at the same time accelerate technology transformation and enhance innovation ability by increasing R&D investment and improving R&D efficiency.

Second, technology trade promotes China’s technological innovation capability and industrial competitiveness.

Through the practice of Chinese enterprises, the mutual promotion relationship between technology trade, technology innovation and industrial competitiveness can be confirmed. Enterprises have the basis of imitation and innovation by introducing technology. In order to achieve digestion, absorption and innovation in a short period of time, they usually increase investment in R&D, accumulate technology stock in R&D, and enhance their technological innovation ability. At the same time, new technologies have also intensified competition in the domestic market, stimulated enterprises that have not introduced technology to increase investment in research and development, and promoted the overall technological capability of the industry, thus promoting industrial upgrading and competitiveness.

(A) technology trade to promote China’s technological innovation ability.

In July 2019, the World Intellectual Property Organization (WIPO) released the Global Innovation Index Report for 2019, which showed that China ranked 14th among 129 economies, and was the only country among middle-income economies to enter the top 30, showing its outstanding innovation strength in patents, industrial designs, the number of trademarks, the export of high-tech and creative products. In 2019, the number of international patent applications in China increased by 11% to 58,990, surpassing the United States for the first time, and the level of innovation investment in China is far lower than that of high-income economies such as the United States, Germany, Britain, Finland and Israel, which is closely related to the way of introducing digestion, absorption and innovation. This paper analyzes the top ten industries of China’s technology import from 2017 to 2019, including eight types of manufacturing. It can be seen that both traditional manufacturing and emerging industries have a consistent dynamic innovation path, that is, technology introduction → increased R&D investment → improved technical level → improved innovation ability.

1. Enterprise technology import has obvious positive effect on the growth of R&D investment.

From the R&D expenditure from 2012 to 2018, it can be found that these eight types of manufacturing industries have maintained steady growth year by year. After 2014, the R&D expenditures of eight types of manufacturing industries all exceeded 10 billion yuan. In 2018, except for the food manufacturing industry, the R&D expenditures of the other seven manufacturing industries all exceeded 40 billion yuan, followed by the communications equipment, computer and other electronic equipment manufacturing industries, electrical machinery and equipment manufacturing industries, with R&D expenditures reaching 227.99 billion yuan and 132.01 billion yuan respectively, accounting for 18.2% and 10.6% of the R&D expenditures of all manufacturing industries in that year. From 2012 to 2018, the investment intensity of R&D funds in eight types of manufacturing industries generally increased, indicating that the introduction of technology directly or indirectly stimulated enterprises to carry out technological innovation. Among the eight types of manufacturing industries, the top two enterprises’ R&D expenditure intensities in 2018 were transportation equipment and special equipment manufacturing, which reached 3.38% and 2.43% respectively, increasing by 1.2 percentage points and 0.95 percentage points respectively compared with 2012. In 2018, except for the food manufacturing industry, the investment level of R&D funds in the other seven types of manufacturing industries exceeded the average level of industrial enterprises and all manufacturing industries in that year.

2. Enterprise technology introduction has obvious positive effect on promoting the growth of invention patents.

Invention patent is the core index to measure technological innovation ability. From 2012 to 2018, the number of effective invention patents in eight manufacturing industries showed a significant increase. Among them, communication equipment, computer and other electronic equipment manufacturing industries had the largest number of effective invention patents, followed by electrical machinery and equipment manufacturing industries. During the period from 2012 to 2018, the total number of invention patents accounted for about 40% of the regulated industrial enterprises. In 2018, the number of valid invention patents in eight manufacturing industries increased significantly, including 300,369 in communication equipment, computer and other electronic equipment manufacturing, 136,014 in electrical machinery and equipment manufacturing, and 97,839 in special equipment manufacturing, which were 3.6 times, 4.3 times and 4.5 times respectively in 2012. There are 78,731 general equipment manufacturing industries, 61,451 chemical raw materials and products manufacturing industries and 45,766 pharmaceutical manufacturing industries, which are 3.4 times, 3.7 times and 3 times that of 2012 respectively; There are 33,164 transportation equipment manufacturing industries and 10,906 food manufacturing industries, which are 5 times and 4.6 times that of 2012 respectively.

From the three traditional manufacturing fields of transportation equipment, medicine and food. Since 2001, the number of patent applications and authorizations for three types of manufacturing industries has increased rapidly. Among them, the number of invention patent applications increased from 917, 4,060 and 984 in 2001 to 69,516, 69,785 and 39,215 in 2019 respectively; In 2001, the number of invention patents granted to the three types of manufacturing industries was zero, and it increased to 20,427, 21,072 and 5,716 respectively in 2019. The average growth rates from 2002 to 2019 were 65.2%, 41.6% and 33% respectively. In 2019, the number of invention patents granted in the transportation equipment manufacturing industry was equivalent to 4.7 times in 2010 and 5,106.8 times in 2002; The number of invention patents granted in pharmaceutical manufacturing industry is equivalent to 2.1 times in 2010 and 369.7 times in 2002; The number of invention patents granted in food manufacturing industry is equivalent to 2.3 times in 2010 and 127 times in 2002. It can be seen that the three types of traditional manufacturing industries have successfully achieved digestion and absorption through technology introduction, and their independent innovation ability has been greatly improved.

From the telecom, radio and television satellite transmission services and computer software two information technology services. From 2001 to 2019, the number of invention patent applications in telecommunications, radio and television satellite transmission services increased from 1,176 to 23,620, with an average annual growth rate of 18.1%; The number of invention patents granted has increased from 0 to 11,521, with an average growth rate of 73.3% from 2002 to 2019. The number of invention patents granted in 2019 is equivalent to 1.7 times that in 2010 and 11,521 times that in 2002. From 2001 to 2019, the number of computer software copyright registrations in China increased rapidly, with only 6,948 in 2001, 81,900 in 2010 and 1,484,400 in 2019, with an average growth rate of 34.7% from 2001 to 2019. The number of registrations in 2019 was equivalent to 18.1 times that in 2010 and 213.7 times that in 2001.

3. Enterprise technology introduction has obvious positive effect on promoting overseas patent growth.

From the perspective of food chemistry, medicine and computer technology industries, the number of overseas patents granted in the three industries increased significantly from 2003 to 2018, from 4, 37 and 27 in 2003 to 87, 764 and 3553 in 2018, with the average annual growth rates of 22.8%, 22.4% and 38.4% respectively. Among them, the number of overseas patents granted for computer technology in 2018 was equivalent to 7 times in 2010 and 131.6 times in 2003; The number of overseas patents granted for food chemical technology is equivalent to 8.7 times in 2010 and 21.8 times in 2003; The number of overseas patents granted for medical technology is equivalent to 4.6 times in 2010 and 20.6 times in 2003.

From the perspective of digital communication industry, the number of overseas patents granted in China’s digital communication industry increased from 1 to 475 from 2000 to 2010, with an average annual growth rate of 85.2%, but the absolute number was lower than that of the United States (4,368), Japan (2,747), South Korea (1,437), France (853), Germany (921) and Sweden. Since 2011, the scale of patent authorization in China’s digital communication industry has increased significantly. From 2011 to 2018, the average annual growth rate of China’s overseas patent grants was 33.8%, while the average annual growth rates of France, Germany, Japan, South Korea, Sweden and the United States were 5.4%, 5%, 4.8%, 15.8%, 15.8% and 8.2% respectively. In 2018, the number of overseas patents granted in China’s digital communication industry was 5,148, equivalent to 10.8 times that in 2010, and it has surpassed France (1,400), Germany (1,225), Japan (4,517), South Korea (4,867) and Sweden (2,843), second only to the United States (8,943).

(B) technology trade to promote industrial export competitiveness.

1. Technology introduction has promoted the growth of product export scale.

From the perspective of eight manufacturing industries in the top ten industries of technology introduction, according to the data of the National Bureau of Statistics, from 2003 to 2019, the total proportion of eight manufacturing industries in export delivery value increased from 51% to 70% in export delivery value. From 2003 to 2019, the average annual growth rate of export delivery value, a listed industrial enterprise in China, was 9.82%, while among the eight manufacturing industries, except transportation equipment manufacturing (4.88%), chemical raw materials and chemical products manufacturing (9.81%), the average annual growth rate of export delivery value in the other six manufacturing industries was higher than the average. Special equipment manufacturing (15.65%), communication equipment, computers and other electronic equipment manufacturing (12.71%), general equipment manufacturing (12.52%), electrical machinery and equipment manufacturing (11.69%), pharmaceutical manufacturing (10.18%) and food manufacturing (9.92%) in turn. From the perspective of export delivery value, in 2019, communication equipment, computer and other electronic equipment manufacturing industry (5605.38 billion yuan), electrical machinery and equipment manufacturing industry (1143.9 billion yuan) and general equipment manufacturing industry (547.7 billion yuan) ranked in the top three, equivalent to 1.5 times, 1.2 times and 1.4 times that of 2011 respectively, equivalent to 6.8 times and 5 times that of 2003. Special equipment manufacturing industry (346.09 billion yuan), chemical raw materials and chemical products manufacturing industry (380.2 billion yuan), equivalent to 1.5 times and 1.1 times respectively in 2011.10.2 times and 4.5 times that of 2003; The transportation equipment manufacturing industry (200.48 billion yuan), pharmaceutical manufacturing industry (141.63 billion yuan) and food manufacturing industry (109.8 billion yuan) are equivalent to 0.3 times, 1.4 times and 1.3 times in 2011 and 2.1 times, 4.7 times and 4.5 times in 2003 respectively.

2. Technology introduction promotes the export growth of high-tech products.

From the perspective of China’s high-tech products trade, the scale of import and export of high-tech products has generally maintained a synchronous growth trend from 2001 to 2019. Since 2004, the export volume of high-tech products has exceeded the import volume. In 2019, the export volume of high-tech products reached 730.75 billion US dollars, equivalent to 1.5 times that of 2010 and 15.7 times that of 2001. There is a "same frequency resonance" effect between the export and import of high-tech products. That is, the higher the export/import ratio of high-tech products, the greater the driving effect of imports on exports. Since 2005, the export/import ratio of high-tech products in China has been above 1.10, reaching 1.20 in 2008, 2009 and 2014, and 1.15 in 2019. Among them, the export/import ratio of high-tech products in the field of computer and communication technology is the highest, increasing from 2.94 in 2005 to 4.02 in 2019.

From the main business income and new product export of electronic and communication equipment and pharmaceutical manufacturing industry. Technology introduction has promoted the industrial scale and export competitiveness. From 2000 to 2018, China’s technology import fees for electronic and communication equipment and pharmaceutical manufacturing industry totaled 121.79 billion yuan and 9.52 billion yuan respectively. From 2000 to 2018, the main business income of China’s electronic and communication equipment manufacturing industry and pharmaceutical manufacturing industry increased from 587.12 billion yuan and 162.75 billion yuan to 9,863.4 billion yuan and 2,391.8 billion yuan respectively, with an average annual growth rate of 17% and 16.1% respectively; The export sales revenue of new products increased from 39.9 billion yuan and 1.52 billion yuan to 1,523 billion yuan and 48.72 billion yuan respectively, with an average annual growth rate of 22.4% and 21.2% respectively. In 2018, the main business income of electronic and communication equipment manufacturing industry was equivalent to 2.7 times that of 2010 and 16.8 times that of 2000 respectively; The income from the main business of pharmaceutical manufacturing industry is equivalent to 1.7 times in 2010 and 14.7 times in 2000. In 2018, the export sales revenue of new products of electronic and communication equipment manufacturing industry was equivalent to 3.6 times that of 2010 and 38.2 times that of 2000 respectively; The export sales revenue of new products in pharmaceutical manufacturing industry is equivalent to 2.7 times in 2010 and 32.1 times in 2000 respectively. At present, China has become the global manufacturing center of consumer electronic products, in which mobile phones and computers account for more than 90% of the global total output.In 2018, the revenue of communication system equipment manufacturing industry increased by 14.6% year-on-year, 15.7 percentage points higher than the global growth rate, and the sales of integrated circuits increased by 20.7% year-on-year, 4.8 percentage points higher than the global growth rate.

Third, the development prospect of China’s technology trade

With China’s continuous opening to the outside world, the ability of independent innovation has been continuously enhanced, and the development prospect of technology trade has become broader and broader.

(A) technological innovation and industrial upgrading requirements will promote the quality of technology trade.

From the perspective of innovation investment, China’s R&D investment intensity has increased from 0.6% in 1996 to 2.2% in 2019. Although it is still lower than the technology and trade powers such as the United States, Japan and Germany, it is higher than the average level of developed countries such as Britain and Italy and the European Union. From the perspective of innovation output, China ranks second in the world in terms of the total number of international scientific and technological papers and the number of citations, and ranks first in the world in terms of the number of invention patent applications and authorizations. Many new technologies, new materials, core components and major equipment have come from scratch, and a series of major breakthroughs have been achieved in strategic emerging industries and cutting-edge technologies, such as high-speed rail equipment, 3D printing, artificial intelligence, quantum computing and other technologies. In recent years, a new round of scientific and technological revolution and industrial transformation, represented by a new generation of information technology, new energy, new materials and life sciences, has flourished around the world. Among them, digital technologies such as cloud computing, big data, Internet of Things, mobile Internet, artificial intelligence, blockchain, virtual reality, quantum computing, and 5G have become the most active areas of technological innovation and industrial transformation. The maturity and large-scale industrial application of these new technologies will continue to spawn new products, new models and new formats, and promote manufacturing and industry. In particular, the accelerated growth of new economic kinetic energy will promote the continuous expansion of technology import and export scale, the continuous improvement of the quality and level of technology import, and accelerate the development of technology export.

(B) "market for technology" and "technology for technology" two-wheel drive will expand the space for technology import.

On the one hand, the space of "market for technology" is getting wider and wider. China has the advantage of super-large-scale market in the world, which will provide industrialized and large-scale space for advanced technologies of all countries in the world, and has the ability to incubate and cultivate new global technologies, providing the basic conditions for "market for technology". The impact of the global COVID-19 epidemic has led to a sharp decline in the international market, accelerating the localization and regionalization of the global industrial chain and supply chain layout. To this end, according to the major changes in China’s development stage and international environment, the CPC Central Committee has put forward a new development pattern in which the domestic big cycle is the mainstay and the domestic and international double cycles promote each other. Under the new development pattern of "double circulation", the continuous release of domestic demand and the upgrading of the level will amplify the advantages of the domestic market and become an important support for the growth of technology imports. In 2019, the total retail sales of consumer goods in China was 41.2 trillion yuan, the per capita disposable income of residents was 30,733 yuan, the consumption tendency was as high as 70%, and the middle class was about 300 million. In 2019, the contribution rate of China’s consumption to economic growth was 57.8%, far below the level of more than 80% in developed countries, which means that consumption still has growth potential. On the other hand, the potential of "technology for technology" is growing. In the past, due to China’s backward technology, it mainly used the advanced technology of developed countries, and formed an obvious vertical division of labor with developed countries in the level of technical division of labor. As China has become a big country in technological innovation, its technological scale and strength have been significantly enhanced, and it has a number of international advanced technologies and a number of high-tech enterprises, and has formed international leading technologies in some fields.The pattern of technology division of labor with developed countries is constantly developing in the direction of horizontal division of labor, thus laying the foundation for new technology import modes such as patent cross-licensing.

(C) open cooperation, innovation and accelerated development will promote the diversification of technology import methods.

With the rapid development of the new scientific and technological revolution, the technical complexity is getting higher and higher, global innovation has entered the era of high-intensity research and development, and the networking of technological innovation has become increasingly obvious, and open cooperation and innovation have become the development trend. With the acceleration of China’s industrial upgrading process, the demand for high-tech will be further improved, and the global allocation of technical elements will be more diversified. In recent years, more and more scientific and technological enterprises in China have acquired key core technologies and jointly developed world-leading technologies through cross-border mergers and acquisitions, cross-border strategic alliances, overseas R&D centers, joint ventures and cross-shareholdings. However, with the strict review system of foreign technology mergers and acquisitions in developed economies such as the United States and the European Union, it will be more difficult for Chinese enterprises to acquire advanced technology through international mergers and acquisitions, and they may be more dependent on other open, cooperative and innovative models. In addition, the flow of leading talents in scientific research has become an important carrier of the flow of technological elements and will become an important mode of technology introduction in China in the future. With the increasingly optimized technological innovation environment in China, the transnational mobility of scientific and technological personnel has been significantly improved, playing an increasingly important role in the introduction of advanced technologies.

(D) changes in the pattern of technological globalization will promote the diversification of China’s technology market sources.

On the one hand, the pattern of scientific and technological globalization is undergoing profound changes. Although the multinational companies in developed countries continue to maintain their technological leading edge, as emerging economies and developing countries continue to open wider to the outside world, accelerate technological accumulation, and promote global technological innovation, the globalization of technological innovation presents a new feature of the parallel development of developed and developing countries, and the comparison of global technological forces has quietly changed, and a new map of innovation activities has gradually taken shape. In 2019, there were 11 emerging economies and developing countries in the top 50 countries of global innovation. In the next 20 years, with the rise of emerging economies and developing countries, the technological innovation ability will be continuously enhanced, which will provide more channels for China’s technology import sources. On the other hand, the technical blockade and containment of China by the United States has become the core content of strategic competition, which has also prompted China to carry out innovative cooperation with technologically advanced economies such as the European Union, Japan and Israel. Hierarchically, in 2019, the European Union replaced the United States as the largest source of technology imports, accounting for more than 30%, and Japan accounted for nearly 19%. Together, they accounted for half of technology imports and may continue to expand in the future. Secondly, Israel has world-leading technologies in life sciences, mobile communication and Internet, technology and finance, artificial intelligence and robotics, automation, industrial applications, clean energy, etc., and there is great room for technical cooperation with China. Thirdly, there is great potential to strengthen technical cooperation with Russia and other BRICS countries and introduce advanced and applicable technologies. For example,Russia has maintained the international advanced level in military industry, nuclear power, aerospace, artificial intelligence and basic research, and bilateral friendly relations have provided a favorable environment for technological innovation cooperation. In 2019, the contract value of China’s technology import from Russia increased by nearly 18 times, from the 19th place in 2018 to the fourth largest source of technology import.

(V) Countries along the Belt and Road will become emerging markets for technology export.

Most of the countries along the "Belt and Road" are developing countries, providing China with a broad technology export market. With the continuous strengthening of China’s interconnection with countries along the route, the technology trade volume between China and countries along the route will also increase. In 2019, my technology export contracts with countries along the route reached US$ 7.71 billion, up 41.8% year-on-year, exceeding the overall growth rate of technology exports by 27.2 percentage points. In 2019, China’s technology export contracts with UAE reached US$ 2.44 billion, up 33 times year-on-year, making it the third largest destination for technology exports, and its technology exports with Bangladesh reached US$ 1.45 billion, up 2.1 times year-on-year. It is foreseeable that countries along the Belt and Road will become important emerging markets for China’s technology export. At present, the main fields of China’s technology export to countries along the route are concentrated in traditional industries such as agriculture, textiles, ships and automobiles. In the future, the fields of technology export will be further expanded, especially the advantageous fields such as information and communication technology, electronic equipment and service outsourcing will become important fields of technology export.

Four, to promote the high-quality development of China’s technology trade policy recommendations

At present, digital technology is leading the in-depth development of scientific and technological globalization, the barriers to the cross-border flow of technological elements are lowered, a large number of new technological achievements are emerging, and the global technology trade space is broader. The technology trade strategy of open cooperation is still an inevitable choice for China to enhance its technological innovation ability and promote the upgrading of industrial structure, and it is also an important way to break through the bottleneck of core key technologies. It is necessary to adhere to the combination of independent research and development of the advantages of the new national system and the active and promising technology introduction strategy, and "promote advantages, make up shortcomings, and build spare tires" to promote China’s independent innovation capability to a new level.

(1) Layout innovation chain based on industrial chain, supply chain and value chain, and build a mutually beneficial and win-win open innovation cooperation system.

Under the background of open economy with closely related global industries and highly complex technologies, it is difficult for any country to realize closed innovation. The interdependence between global industrial chain and supply chain is an important foundation and prerequisite for open cooperative innovation. For example, in May 2020, the US Department of Commerce allowed American companies to cooperate with Huawei to formulate 5G network standards, which objectively formed a win-win situation. Due to Huawei’s position and influence in the 5G industrial chain, American companies can’t bypass Huawei to participate in the formulation of 5G standards. The U.S. government’s crackdown on Huawei actually restricts domestic companies’ participation in the formulation of 5G standards, so they have to relax the cooperation between domestic companies and Huawei in the formulation of standards. For Huawei, the participation of the United States in the formulation of 5G standards can bring greater value to international standards. If it does not cooperate, it will cause harm to 5G standards and it will also be unfavorable to Huawei. With the accumulation of technology and the enhancement of independent research and development capability in China, technology introduction will focus more on cutting-edge technologies. With the intensification of technology competition and blockade in the big country game, the difficulty coefficient of direct purchase is increasing. Therefore, relying on the industrial chain and supply chain, we should explore new mechanisms of technical cooperation with developed economies such as the European Union, the United States, Japan and the United Kingdom, and change from the one-way traditional mode of introduction-imitation-learning to the two-way interactive innovation mode of co-creation, sharing and win-win. In addition, we should actively expand technical and trade cooperation with other countries. For example, the content of technology trade should be added in FTA negotiations, a bilateral technical cooperation framework should be signed, and in-depth cooperation should be carried out in technology research and development, technology transfer or licensing, technical consultation and services.

(2) Give full play to the advantages of being a big intellectual property country and improve the level of intellectual property trade.

Strengthening the export of intellectual property rights can not only expand the scale of service export, but also effectively promote product export. It is estimated that every $100 million of patented technology transferred from developed countries can drive the sales of complete sets of equipment and ancillary products of about $5 billion. To this end, we must vigorously implement the export strategy of intellectual property rights. We should pay attention to the cultivation of full value chain services from the creation, application and transformation of intellectual property rights, operational services to intellectual property protection. With the "softening" trend of technology trade, the technical competition among countries is increasingly reflected in the strategic competition of intellectual property rights. China should pay attention to using patent strategy to expand the export market of intellectual property rights and promote the upgrading of technology export structure. Encourage technology export enterprises to attach importance to the cultivation of intellectual property competitiveness, scientifically evaluate the value of intellectual property rights, realize the interactive development of innovation, industrial upgrading and intellectual property management, vigorously cultivate brand enterprises with independent intellectual property rights, and expand the export scale of intellectual property rights such as patents and proprietary technologies. Encourage enterprises to implement the patent network strategy to speed up the layout of overseas intellectual property rights, improve overseas intellectual property protection institutions, provide convenience for enterprises to obtain overseas patents and safeguard their rights, and help enterprises cope with overseas intellectual property risks. Second, we should strengthen the protection of intellectual property rights and optimize the technology transfer environment. China has established relatively perfect laws and regulations on intellectual property protection, and should constantly improve the early warning, supervision and law enforcement system, respond to the concerns of technical cooperation countries and multinational companies in China in a timely manner, severely crack down on infringement and illegal acts according to law, and earnestly safeguard the intellectual property rights interests of foreign-funded enterprises.Improve the intellectual property cooperation mechanism with major trading partners such as the United States, the European Union and Japan, and strengthen cooperation in intellectual property arbitration and dispute settlement. Third, we should advocate qualified enterprises and multinational companies to use patent cross-licensing. By signing patent cross-licensing with competitors, it is conducive to integrating technological advantages, eliminating intellectual property obstacles in opening up the international market, avoiding infringement litigation disputes and reducing transaction costs.

(3) Vigorously attract overseas leading talents and promote the global advanced technology transfer.

Overseas leading talents are the key elements of technology transfer. Local governments should be encouraged to increase efforts to attract overseas students to return home and overseas senior talents to work in China, and make specific arrangements on how to support studying abroad, encourage returning home and come and go freely. We will attract overseas high-tech talents through various ways, such as scientific research funding subsidies, wages and salaries, tax concessions, and stock option incentives, and increase policy support in housing placement, children’s schooling, household registration, and entry and exit convenience, so as to create good conditions for them to live and work in peace and contentment. Combine talent introduction with career development organically, so that talents can not only be attracted, but also retained, so that they can have space for innovation, platform for entrepreneurship and development, and create a group of overseas leading talents standing at the forefront of world science and technology.

(D) to further improve the technology trade platform, strengthen the construction of policy support system.

Relying on major international exhibitions such as Service Trade Fair, China International Import Expo(CIIE) and Hi-Tech Fair, we will provide enterprises with more opportunities for technical trade and international technical cooperation and exchange. Explore the establishment of technology trade markets in pilot free trade zones such as Beijing, Shanghai, Shenzhen, Xi ‘an and Nanning. Increase subsidies and tax incentives for R&D investment of enterprises, and provide more convenient qualification certification and application process. Increase support for technology export enterprises, reduce financing costs and guarantee requirements, reward software projects that help domestic enterprises to provide mature software solutions and technical support overseas, and support their product development and localization applications. Allocate special funds to support the development of technology trade in the service trade innovation and development guidance fund, and encourage local governments to set up matching funds for technology trade.

(5) Comply with the changing trend of global technical trade rules and actively participate in the construction of international technical trade rules and standards.

First, we should actively study the latest progress and trends of multilateral and bilateral trade systems and regional technical trade agreements. Advocate the theme of "development" in the WTO and oppose all forms of protectionism. At the same time, we should avoid western countries from forming a rule-making circle in digital technology to exclude China. For example, China’s digital governance models are different from those of the United States and the European Union, and there is a strong geostrategic and mode confrontation among the three models, which is difficult to unify and be compatible, so it is necessary to establish a dialogue mechanism. Second, we should advocate the principle of neutrality in the formulation of international standards related to technology trade, which is not affected by political factors in various countries, so that international standards can be widely and unanimously supported and maintain their strong vitality. Third, it is necessary to establish a mechanism with enterprises as the main body and relevant organizations participating in coordination, so as to promote China’s technical standards with advantages and characteristics to become international standards. Deepen standardization cooperation with the focus on countries along the "Belt and Road", promote mutual recognition of standards between China and countries along the route, and improve the right to speak on technical trade rules. Fourth, we should attach importance to the training of technical trade negotiators, especially professionals who are proficient in international rules of technical trade and foreign-related technical trade litigation and negotiation, and encourage them to participate in the formulation of international rules and standards in relevant international organizations.

(6) Deepen the reform of the technology trade management system and consolidate the technology innovation system combining Industry-University-Research and China.

Accelerate the transformation of government management functions, pay more attention to the role of market mechanism in the institutional supply of technological innovation, pay attention to the market-oriented allocation of innovative elements, and give play to the main role of various enterprises. Smooth the collaborative innovation mechanism between enterprises, universities, scientific research institutions and users, promote the coordinated development of large, medium, small and micro enterprises in innovation chain, improve various technical exchange and cooperation platforms, and strengthen the construction of various industrial innovation alliances.

As the Spring Festival approaches, the taste of the year is getting stronger all over the country, and the sales of new year goods are getting stronger.

CCTV News:With the approach of the Spring Festival, the flavor of the year is getting stronger all over the country, and the sales of traditional handicrafts such as lanterns and Spring Festival couplets and new year goods such as bacon are booming.

These days, the streets and alleys of Suining, Sichuan are covered with red lanterns, and there is a festive and lively atmosphere everywhere. Some urban landscapes with red, yellow and green as the main colors at intersections have also appeared one by one.

In the market, decorations such as red Spring Festival couplets, various blessings and Chinese knots are dazzling, and many window grilles, pillows and red envelopes with tiger characters and tiger patterns are also very popular. In addition to traditional holiday supplies, flowers have also become the choice of many citizens. Adding some auspicious flowers to the family not only brings a good mood for the new year, but also dresses up the festive atmosphere.

In Sinan, Guizhou, Tujia bacon such as sausage is popular in the market.

Due to the epidemic, many Sinan people who are away from home choose to celebrate the New Year on the spot, and buying local new year’s goods through the Internet has become their first choice to feel the taste of their hometown. Sinan Tujia preserved meat has a long history. It enters the twelfth lunar month every year, and the preserved meat is fragrant everywhere in Sinan urban and rural areas. People cut pork into strips and chunks when making preserved meat, and pickled it with more than 10 seasonings such as pepper, pepper and star anise for 5-mdash; After 7 days, it was baked with smoke and charcoal fire.

In Nanning, Guangxi, on the eve of the Spring Festival every year, festive New Year’s Eve flowers are an essential new year’s goods in many citizens’ shopping lists.

As the Spring Festival approaches, the sales of handicrafts symbolizing festive atmosphere in Gaoping, Shanxi are hot. In the manual lantern production workshop, workers step up the production of various lanterns, with a clear division of labor in painting, pasting and assembly. It takes at least one day to make an ordinary lantern. Handmade workers integrate modern aesthetics on the basis of traditional handicrafts, and social fire props such as dragon dance, lion dance, dry boat and Jiulian lantern create a strong auspicious and festive flavor.

2300000000+!

During the Spring Festival holiday in 2025, the number of traffic trips exceeded 2.3 billion.

On the 5th, the reporter learned from the 2025 Spring Festival travel rush Comprehensive Transportation Work Class that during the Spring Festival holiday this year (from January 28th to February 4th), the cross-regional personnel flow of the whole society was 2,306.845 million.

Specifically, the passenger traffic by railway is 96.26 million, the passenger flow by road is 2,182.93 million (the passenger travel by non-operating passenger cars on expressways and provincial highways is 1,989.65 million, and the passenger traffic by road is 193.28 million), the passenger traffic by waterway is 9.413 million, and the passenger traffic by civil aviation is 18.2415 million.

Summary of the Speech at the Theoretical Seminar on "Strictly Administering the Party in an All-round Way" of the Forum on Governing the Country

  Strictly administering the Party in an all-round way is the fundamental guarantee for completing the historical mission.

  Feng Jun, Deputy Director of the Central Party History Research Office

  Realizing the great rejuvenation of the Chinese nation is the greatest dream of the Chinese nation in modern times, and it is also the historical mission of the Communist Party of China (CPC). Under the leadership of the CPC Central Committee with the Supreme Leader as the core, we have never been closer to the goal of realizing the great rejuvenation of the Chinese nation. In his important speech on "July 26th", General Secretary of the Supreme Leader emphasized that if the Party wants to unite and lead the people in a great struggle, advance a great cause and realize a great dream, it must unswervingly uphold and improve the Party’s leadership, unswervingly push forward the new great project of Party building, and make the Party stronger and stronger.

  Strengthen political construction, comprehensively strengthen the party’s leadership and enhance the party’s cohesion, combat effectiveness, leadership and appeal. Party, government, military and civilian studies, east, west, north and south, the party is the leader of everything. Party member cadres should strictly abide by political discipline and rules, safeguard the authority of the CPC Central Committee, safeguard the unity and centralized leadership of the Party, firmly establish political awareness, overall situation awareness, core awareness and conformity awareness, and always maintain a high degree of consistency with the CPC Central Committee with the Supreme Leader as the core in ideological and political actions.

  Strengthen the education of ideals and beliefs and stick to the spiritual home of communist party people. The lofty ideal of communism and the common ideal of Socialism with Chinese characteristics are the spiritual pillar and political soul of the Communist Party of China (CPC) people. The majority of party member cadres must unswervingly adhere to the guiding position of Marxism, earnestly study the theoretical systems of Marxism–Leninism, Mao Zedong Thought and Socialism with Chinese characteristics, conscientiously study the spirit of the series of important speeches by the Supreme Leader General Secretary and the new ideas, new ideas and new strategies for governing the country and making up the "calcium" of the spirit.

  Adhere to the close combination of ideological party building and institutional party management, and put institutional construction throughout all aspects and the whole process of party building. Since the 18th National Congress of the Communist Party of China, the CPC Central Committee has formulated and revised a number of inner-party laws and regulations, which has tightened the cage of the system. The promulgation and implementation of the inner-party laws and regulations, such as the Regulations on Patrol Work in the Communist Party of China (CPC), the Regulations on Accountability in the Communist Party of China (CPC), the Code of Integrity and Self-discipline in the Communist Party of China (CPC), and the Regulations on Disciplinary Actions in the Communist Party of China (CPC), have enabled the party to be strictly governed in an all-round way. In particular, the Sixth Plenary Session of the 18th CPC Central Committee adopted "Several Guidelines on Inner-Party Political Life under the New Situation" and "Regulations on Inner-Party Supervision in the Communist Party of China (CPC)", which provided an important system for strengthening and standardizing inner-party political life and strengthening inner-party supervision under the new situation.

  Adhere to strict management of officials and do a good job of leading cadres, the "key minority." Adhering to the correct orientation of selecting and appointing people, selecting and appointing cadres must adhere to the principle of having both ability and political integrity, putting morality first, adhering to all corners of the country, appointing people on their merits, and adhering to the standards of good cadres with firm beliefs, serving the people, being diligent and pragmatic, daring to take responsibility, and being honest and clean. Leading cadres should be strictly self-disciplined, cautious and cautious, start from themselves and manage from people around them.

  Maintain the overwhelming trend of the anti-corruption struggle. Shortly after the 18th National Congress of the Communist Party of China closed, the Political Bureau of the Central Committee formulated and promulgated eight regulations, which sent a strong signal that discipline should be maintained and the Party should be strictly governed. Since the 18th National Congress of the Communist Party of China, the Central Committee of the Communist Party of China, with the determination of a strong man to break his wrist, curbs the bones and cures the poison and cures the furuncle with fierce drugs, and insists that corruption must be countered and greed must be eliminated, thus effectively curbing the spread of corruption. To adhere to the comprehensive and strict administration of the party, we must maintain the overwhelming trend of the anti-corruption struggle and constantly win the hearts and minds of the party.

 

  Stressing politics is a prominent feature and advantage of our party.

  Tang Zhouyan, Party Secretary of Shandong Academy of Social Sciences

  General Secretary of the Supreme Leader has repeatedly stressed that our party, as a Marxist political party, stresses politics as a prominent feature and advantage. Deeply understanding and grasping the spiritual essence of this important thesis is of great significance for promoting the comprehensive and strict management of the Party, advancing the new great project of Party building and winning new victories in Socialism with Chinese characteristics.

  Taking a clear-cut stand and talking about politics is an important magic weapon for the Communist Party of China (CPC) people to defeat the enemy. As a Marxist political party, the Communist Party of China (CPC) has never denied his political attributes, and has always taken a clear-cut stand on politics. This is our party’s outstanding characteristics and advantages, and it is also an important magic weapon for our party to grow stronger and defeat the enemy. As early as the Gutian Conference, Comrade Mao Zedong clearly proposed to "improve the political level within the Party" and "make party member’s thoughts and life within the Party politicized and scientific". Since the 18th National Congress of the Communist Party of China, the CPC Central Committee with the Supreme Leader as the core has unswervingly promoted the comprehensive and strict administration of the Party and repeatedly stressed that leading cadres should take a clear-cut stand and stress politics. Throughout the course of our party’s struggle, when the whole party stresses politics and the political life within the party is normal and healthy, the party’s cause will flourish; On the contrary, it may be full of ills and cause serious losses to the party’s cause. Standing at a new historical starting point, if we want to create a new situation in the cause of Socialism with Chinese characteristics, we must carry forward this outstanding feature and advantage of our Party and stress politics with a clear-cut stand.

  Take a clear-cut stand and say that the key to politics is to firmly establish the "four consciousnesses". Strengthening the "four consciousnesses" is the concentrated embodiment and inevitable requirement of taking a clear-cut stand and stressing politics. We should firmly establish political consciousness, adhere to the correct political direction and position, maintain a clear political mind and keen political discernment, always take the party’s banner as the banner, take the party’s direction as the direction, take the party’s will as the will, and maintain a high degree of political consistency with the CPC Central Committee; Firmly establish a sense of the overall situation, establish a correct view of the overall situation, consciously understand, obey and safeguard the overall situation, and effectively unify thoughts and actions with the decision-making and deployment of the CPC Central Committee. As long as things that are beneficial to the overall situation are done well, as long as words and deeds that hinder the overall situation are resolutely opposed, the whole party will always be guaranteed to play a game of chess; Firmly establish the core consciousness, resolutely safeguard the core position of the supreme leader’s general secretary, take the maintenance of the core as the first political requirement, and achieve full trust in thought, resolute maintenance in politics, conscious obedience in organization, deep recognition in emotion, and always follow in action; Firmly establish a sense of conformity, take the initiative to align with the CPC Central Committee with the supreme leader as the core, take the initiative to align with the party’s theory, line, principles and policies, and take the initiative to align with the decision-making and deployment of the CPC Central Committee.

  To promote the comprehensive and strict management of the party and develop in depth, we must take a clear-cut stand and stress politics. Standing at a new historical starting point, promoting the comprehensive and strict development of the party requires us to speak politics more clearly. Since the 18th National Congress of the Communist Party of China, the CPC Central Committee with the Supreme Leader as the core has persisted in focusing on, examining and solving outstanding problems within the Party politically, and has grasped the root of strictly administering the Party in an all-round way. In the process of strictly administering the party in an all-round way, we can’t just solve the problem of corruption and not solve political problems. Political problems of cadres are no less harmful to the party than corruption, and some are even more serious than corruption. At present, the strict administration of the party in an all-round way has entered a new stage, which requires us to speak politics more clearly.

 

  Firmly establish the "four consciousnesses" and resolutely safeguard the authority of the CPC Central Committee

  Zhang Lei, deputy editor-in-chief of Economic Daily

  Firmly establishing the "four consciousnesses" and resolutely safeguarding the authority of the CPC Central Committee are the inevitable requirements for upholding and consolidating the party’s leadership and ensuring the smooth development of the cause of the party and the state. The Sixth Plenary Session of the 18th CPC Central Committee pointed out: "A country and a political party have a core of leadership." "Resolutely safeguarding the authority of the CPC Central Committee and ensuring that all party orders are prohibited are the future and destiny of the party and the country and the fundamental interests of the people of all ethnic groups in the country."

  From the development history of Marxist political parties, it is a basic principle of Marxist political party construction to safeguard the central authority and the core of leadership. In the practice of leading the communist movement, Marx and Engels always emphasized the importance of authority, which they believed was related to the success or failure of the revolutionary cause. The history of socialist development in the world shows that the proletariat not only needs authority to carry out revolution, but also needs such authority in the process of consolidating political power, construction and reform. The failure of the CPSU also illustrates this truth from the opposite side: once a Marxist political party with a glorious history and once very strong destroys the central authority and abandons the party’s leadership, it will inevitably lead to the tragic situation of the party and the country. This is a lesson of blood, which we must remember deeply.

  Judging from the development history of our party in 1996, maintaining the central authority and the core of leadership is the fundamental guarantee for the continuous development of the party’s cause and the long-term stability of the country. Comrade Deng Xiaoping emphasized: "Any leading collective must have a core, and leadership without a core is unreliable.". He also pointed out that in history, the main reason for the frustration and failure of our party before Zunyi Conference was that it did not form a mature CPC Central Committee and a core of leadership that was widely expected. It was not until the central collective leadership with Comrade Mao Zedong as the core was formed that the China Revolution embarked on the smooth development. Similarly, in the historical process of promoting reform and opening up, the mature core of leadership also plays an irreplaceable role. The Communist Party of China (CPC) has gone through a glorious course of 96 years and has been in power for 68 years in a row. The reason why he has achieved the historic achievement of standing out from the rest of the world is that he has always emphasized upholding the leadership of the Party and safeguarding the authority of the CPC Central Committee.

  Judging from the conditions of the times faced by our party, maintaining the central authority and the core of leadership is the need to shoulder the historical responsibility of the party and complete the historical task of the party. Great and profound changes are taking place in the world today. China is in the decisive stage of building a well-off society in an all-round way. The Party is faced with the historical task of carrying out great struggles, building great projects, advancing great undertakings and realizing great dreams. Our party has made great achievements that have attracted worldwide attention and accumulated extremely rich ruling experience, but the "four tests" and "four dangers" are still grim, and the "rushing for the exam" is far from over. Today, Socialism with Chinese characteristics is like a big ship sailing through the waves in the sea of Wang Yang. More than ever, it needs a capable, experienced and authoritative helmsman to guide it. Since the 18th National Congress of the Communist Party of China, General Secretary of the Supreme Leader has led the whole party, the whole army and the people of all nationalities in China to create a brand-new situation in the development of Socialism with Chinese characteristics’s cause, and has made a series of great achievements with great practical significance and far-reaching historical significance in reform, development and stability, internal affairs, foreign affairs and national defense, and in managing the party, country and army, and won the heartfelt love and support of the whole party, the whole army and the people of all nationalities in China. General Secretary of the Supreme Leader is the core of the CPC Central Committee and the whole Party formed in the practice of the new great struggle. Firmly safeguarding the authority of the CPC Central Committee and the core position of the Supreme Leader General Secretary are important guarantees for us to strive for new and greater victories.

 

  Serious inner-party political life is the basis of strictly administering the party in an all-round way.

  Ji Zhengju, Deputy Director of the Central Compilation Bureau

  The General Secretary of the Supreme Leader pointed out: "Serious inner-party political life is the fundamental basic work of strictly administering the party in an all-round way and is a major task of the whole party." If the party wants to manage the party, it must manage the political life within the party; To strictly manage the party, we must start from the political life within the party. The "Several Guidelines on Political Life within the Party under the New Situation" and a series of important expositions by the Supreme Leader General Secretary on comprehensively administering the Party strictly have profoundly expounded the great significance, fundamental principles, basic requirements and scientific path of serious political life within the Party under the new situation, which is a scientific summary and theoretical sublimation of our Party’s experience in managing the Party and providing important compliance and institutional guarantee for comprehensively administering the Party strictly.

  Serious inner-party political life is the Communist Party of China (CPC)’s fine tradition and political advantage. Over the past 96 years, one of the important reasons why our party has been able to maintain its advanced nature and purity forever is to attach importance to the role of inner-party political life in party building and make it a fine tradition and heirloom. As early as 1926, our party began to use the concept of party life in the central document. In the long-term practice, our party has gradually formed the basic norms of inner-party political life with seeking truth from facts, integrating theory with practice, keeping close contact with the masses, criticizing and self-criticizing, democratic centralism and strict party discipline as the main contents, which has provided an important guarantee for the development of the cause of the party and the state.

  Serious inner-party political life is the golden key to solve the contradictions and problems existing in the party. History has proved that when the political life within the party is serious, the cause of the party and the people will flourish; Whenever the political life within the party is abnormal, the cause of the party and the people will encounter setbacks. One of the most important reasons why the Communist Party of China (CPC) can constantly overcome all kinds of difficulties and dangers and move from victory to victory is that he can overcome all kinds of contradictions and negative factors existing in the party in a timely and effective manner through regular, serious and serious political life within the party, such as dogmatism, empiricism, liberalism, hedonism, bureaucracy and sectarianism. Under the new situation, only by effectively solving the problems existing in the party through the political life within the party can our party maintain its advanced nature and purity in the face of "four major tests" and "four dangers".

  Serious inner-party political life is a melting pot for party member cadres to exercise their party spirit. Political life within the Party is the main platform for Party organizations to educate and manage party member and exercise party spirit. Party member cadres’ ability and prestige are closely related to whether they have been seriously trained in inner-party political life. Serious inner-party political life is like a melting pot, in which party member cadres consciously accept the baptism of thought and party style and discipline, and constantly temper party spirit, so that they can keep fit and be tempered into steel.

  Serious inner-party political life is a purifier of pure party style. What kind of inner-party political life there is, there is what kind of cadre style in party member. Political life within the party can not only purify the party style, but also promote the improvement of political style, folk customs and social atmosphere by stirring up turbidity, strengthening the body resistance and eliminating evil spirits. It can not only ensure the purity and health of cadres in party member, but also enable the Party organizations to constantly eliminate "dust" and "viruses", realize self-purification, self-improvement, self-innovation and self-improvement, and promote the continuous development of the comprehensive and strict administration of the Party.

 

  Strictly administering the Party in an all-round way inevitably requires strengthening inner-party supervision.

  Xie Feng, Professor of Party Building Teaching and Research Department of Central Party School

  General Secretary of the Supreme Leader attaches great importance to strengthening inner-party supervision and has made many important expositions on strengthening inner-party supervision. Both history and reality show that strengthening inner-party supervision is an inevitable requirement of strictly administering the party in an all-round way.

  Deeply understand the significance of inner-party supervision to the comprehensive and strict administration of the party. This important significance can be understood from three aspects: first, from the historical experience of the party in power. Our party has deeply realized in its ruling practice that unsupervised power will inevitably lead to corruption, which is an iron law. As the ruling party, the biggest challenge our party faces is how to effectively supervise the power and keep the party’s advanced nature and purity forever. Among them, the most important supervision is the party’s own supervision, that is, inner-party supervision. The second is to learn from the failure of communist party in the Soviet Union. One of the main reasons for the collapse of the CPSU in the 1990s after more than 70 years in power was the lack of inner-party supervision and the abuse of power. This warns us that we should attach great importance to inner-party supervision and strictly manage the party. The third is to understand the problems faced by our party in the new period. At present, there are still many problems that need to be solved urgently in our Party. One of the important reasons is that the Party rules and regulations in party constitution have not been well implemented. To solve the problems existing in the Party, we must tighten inner-party supervision, promote the management of the Party from "loose and soft" to "strict and hard", ensure the effective implementation of party rules and discipline in party constitution, and provide an important guarantee for the comprehensive and strict management of the Party.

  Promote the comprehensive and strict administration of the party by strengthening inner-party supervision. First, build a scientific inner-party supervision system. At present, a new inner-party supervision system with clear division of labor, clear responsibilities and three-dimensional complementarity has been formed, namely, unified leadership by the CPC Central Committee, comprehensive supervision by party committees (party groups), special supervision by discipline inspection organs, functional supervision by party departments, daily supervision by party grass-roots organizations and democratic supervision by party member. We should give full play to the role of the inner-party supervision system and promote the comprehensive and strict management of the party. Second, seize the "key minority". The object of inner-party supervision includes ordinary party member, but the focus is on leading organs and leading cadres, which is the key to strictly administering the party and strengthening inner-party supervision. Grasping the "key minority", especially solving the supervision problem of the top leaders, can play a leading and exemplary role and is of great benefit to curbing corruption and creating a good political ecology. Third, make full use of various means of inner-party supervision. These means include criticism and self-criticism, reminding conversation and admonishing conversation, debriefing and commenting on honesty, letters and visits, etc. Among them, we should pay special attention to the role of criticism and self-criticism. Criticism and self-criticism are the party’s fine traditions and good ways to find and correct shortcomings and mistakes. We must make good use of this weapon for self-defense and treatment. Fourth, strengthen the formulation and implementation of the inner-party supervision system. Adhere to the problem orientation and improve the relevant system of inner-party supervision; By adhering to the above rate, strengthening study and education, and strengthening supervision and inspection, we will do a good job in the implementation of the inner-party supervision system. Fifth, adhere to the combination of inner-party supervision and non-party supervision. The ruling position of our party determines that inner-party supervision is the most basic and the first.Only by strengthening inner-party supervision can we promote non-party supervision. At the same time, we should pay attention to the role of non-party supervision, realize the effective combination of inner-party supervision and non-party supervision, complement each other’s advantages and exert their overall strength, so as to maximize the effectiveness of supervision.

 

  Strengthening ideals and beliefs and supplementing the "calcium" of the spirit

  Guo Guangyin, former Party Secretary of Southeast University

  Communist party people’s ideals and beliefs are their faith in Marxism, socialism and communism, and their loyalty to the Party and the people. General Secretary of the Supreme Leader pointed out: "Ideals and beliefs are the spiritual’ calcium’ of communist party people. Without ideals and beliefs, ideals and beliefs will be’ calcium deficiency’ and’ rickets’." Today, if we want to push forward the new great project of party building, strictly manage the party and make the party stronger, we must ask party member cadres to make up the spiritual "calcium" of ideals and beliefs more consciously.

  To strictly manage the party in an all-round way, we must first strengthen our ideals and beliefs. Strictly administering the party in an all-round way is a systematic project, and strengthening ideals and beliefs is the theme that runs through this project. Judging from the Party’s organization, the Communist Party of China (CPC) adhered to the ideals of socialism and communism, which enabled the Party to make clear the direction of its efforts ideologically and politically, unite people’s strength, and maintain unity and unity. From party member’s individual point of view, ideals and beliefs are the political foundation and spiritual home for communist party people to settle down, which plays a key role in guiding and directing their thoughts and actions. Some party member cadres are politically deteriorated, economically greedy, morally degenerated and corrupted in life. In the final analysis, they lack the "calcium" of the spirit of ideals and beliefs.

  Strengthening ideals and beliefs should be based on "four possibilities" and "six noes". Regarding whether party member cadres have ideals and beliefs, the Supreme Leader General Secretary put forward the objective criterion of "four possibilities". He pointed out, "There are objective standards to measure whether a Communist party member and a leading cadre have lofty ideals of communism. It depends on whether he can adhere to the fundamental purpose of serving the people wholeheartedly, whether he can bear hardships first and enjoy later, whether he can work diligently and be honest, and whether he can work hard, struggle and give all his energy and even his life for his ideals." As for the firmness of ideals and beliefs, the General Secretary of the Supreme Leader further put forward the standard of "six noes", which mainly depends on whether party member cadres can have political determination in the face of major political tests, whether they can establish a firm sense of purpose, whether they can be extremely responsible for their work, whether they can bear hardships first and enjoy them later, whether they can bravely shoulder heavy burdens in the face of urgent and dangerous tasks, and whether they can withstand the temptation of power, money and beauty. The criteria of "Four Musts" and "Six Musts" endow the firm ideals and beliefs with real connotations, and provide a practical yardstick for each Communist party member to test and reflect on his political consciousness, emotional attitude and behavior.

  Make up the "calcium" of the spirit of ideals and beliefs based on reality. With ideals and beliefs and objective standards to follow, it is not enough to ensure that ideals are always firm, beliefs are always persistent, and actions are always correct. Firm and persistent ideals and beliefs will not come into being spontaneously, but we should try our best to learn, believe, understand and do things all our lives. Only by making efforts to supplement the "calcium" of the spirit of ideals and beliefs based on reality can we cultivate a "indestructible body" that can stand firm, stand the test, resist corrosion and resist risks. The firmness of ideals and beliefs comes from the power of truth, which requires party member cadres to seriously study Marxist classics and systematically master the basic Marxist theories, standpoints and methods. To strengthen ideals and beliefs, we must also strengthen the cultivation of party spirit and constantly strengthen the "four consciousnesses." The firmness of ideals and beliefs will ultimately start with doing a good job in front of you.

 

  Democratic centralism is an important magic weapon to safeguard the unity and unity of the party.

  Xin Xiangyang, Vice President of Information and Information Research Institute of China Academy of Social Sciences

  Democratic centralism is the fundamental organizational system and leadership system of our party, the basic criterion for regulating political life and handling relations within the party, a scientific and effective system for ensuring the correct formulation and implementation of the party’s line, principles and policies, and an important magic weapon for safeguarding the party’s unity and unity.

  Democratic centralism ensures the unity of the will of the whole party and lays an ideological foundation for the unity and unity of the party. There are many factors that affect the unity and unity of the party, one of which is the ideological factor. Our party has always emphasized the principle and system of democratic centralism. With this principle and system, we can deny the party’s leadership, China’s socialist system and reform and opening up, violate, distort and deny the party’s basic line, distort, vilify and deny Socialism with Chinese characteristics’s words and deeds, distort, vilify and deny the party’s history, People’s Republic of China (PRC)’s history and the people’s army’s history, and distort, vilify and deny the party’s leaders and heroic models.

  Democratic centralism ensures the healthy development of political life within the party and provides basic norms for the unity and unity of the party. The "Several Guidelines on Inner-Party Political Life under the New Situation" adopted by the Sixth Plenary Session of the 18th CPC Central Committee pointed out: "In the long-term practice, our party has insisted on carrying out serious inner-party political life as an important task of party building, and formed the basic norms of inner-party political life with seeking truth from facts, integrating theory with practice, keeping close contact with the masses, criticizing and self-criticizing, democratic centralism and strict party discipline as the main contents." As the basic norm of inner-party political life, democratic centralism is conducive to unifying party member’s ideological understanding, solving some problems within the party and ensuring the healthy development of inner-party political life.

  Democratic centralism ensures the correct orientation of selecting and employing people within the party and lays a cadre foundation for the unity and unity of the party. The development of the party’s cause is inseparable from a grand cadre team, and the formation of this team is based on democratic centralism. Based on democratic centralism, our party can constantly select outstanding talents to the jobs it needs. As the General Secretary of the Supreme Leader said: "Our current cadre selection mechanism is also at the first level. For example, I have worked in the countryside, served as the party branch secretary of the brigade, and worked in counties, cities, provinces and the central government." The first-level selection mechanism makes the selection of cadres not only reflect the wishes of the people, but also stand the test of political life. Without democratic centralism, some cadres will believe in the "circle culture" of cliques and consider how to pull relationships and find ways. If we earnestly implement the requirements of democratic centralism, we can train a large number of good cadres with firm beliefs, serving the people, being diligent and pragmatic, daring to take responsibility, and being honest and clean.

  Practice has proved that democratic centralism is an important magic weapon to stimulate the creativity and vitality of the party and maintain the unity and unity of the party. We should adhere to the principle of democratic centralism to handle all kinds of relations within the Party, solve contradictions and problems within the Party, jointly safeguard unity based on the principle of party spirit, and ensure that the Party always keeps ahead of the times in the historical process of profound changes in the world situation, always becomes the backbone of the people throughout the country in the historical process of coping with various risks and tests at home and abroad, and always becomes a strong leadership core in the historical process of upholding and developing Socialism with Chinese characteristics.



  People’s Daily (September 20, 2017, 19th edition)

Shi Ce’s Danxin in Guo Liang’s Poems

Guo Liang was an early proletarian revolutionary of our party, a famous leader of the workers’ movement, and a close comrade-in-arms who organized and led the workers’ movement with Mao Zedong. Mao Zedong praised him as "a famous organizer of the workers’ movement". On March 29th, 1928, Guo Liang was secretly killed by Kuomintang reactionaries in Qianping, Simenkou, Changsha, at the age of 27. In Guo Liang’s short life, although there are not many poems left behind, they show Shi Ce’s unyielding heart and courage to fight.

"Ask the society, what is the truth?"

Guo Liang, formerly known as Guo Jing Jia, was born in 1901 in Wenjiaba, Sheshan, Tongguan Town, Wangcheng County, Hunan Province (now Guo Liang Village, Tongguan Street). At the age of 11, he changed his name to Guo Liang, hoping to be as resourceful as Zhuge Liang. When Guo Liang was a teenager, he paid close attention to the poor life of the people who were hungry and toiling, and thought deeply about it. He wrote a sharp new-style poem "Ask the Society": A strange question is not worth mentioning by scholars and juren, and it is also common sense for teachers, but they know nothing about it! Where did the Gu Mi of the rich come from? Why do farmers carry grain into the rich man’s barn? Ask the society, what is the truth? Where did the rich man’s house come from? Why do poor people build houses and rich people live in peace? Ask the society, what is the truth? Where do the clothes of the rich come from? Why don’t people who grow cotton and weave clothes cover their bodies? Ask the society, what is the truth? People live in the same world, why are the rich and the poor different? Ask the society, what is the truth? This poem tells the people’s sufferings in plain language and lashes out at social injustice in extremely sharp language, which is particularly easy to resonate and soon spread.

It is also in order to answer these doubts in Ask the Society that Guo Liang read more and more historical books, cared about his family and country, and began to explore the truth actively. In the autumn of 1915, 14-year-old Guo Liang was admitted to Changjun Middle School. With the anti-Japanese patriotic struggle of Hunan people constantly emerging, Guo Liang participated in the patriotic anti-Japanese struggle of Changsha students. In 1916, Guo Liang saw the heads of the murdered revolutionaries on the streets of Changsha, and angrily chanted poems: "How much blood and tears are there?"? Revenge needs to pour water into the cave, and patriotism can’t be afraid of hanging its head! " Grief and indignation gushed out from this poem, and the patriotic fire took root in the young man’s heart.

"A trickle of water sinks into a huge stream"

Once the patriotic fire is lit, it burns in Guo Liang’s young chest. He sympathized with the sufferings of the people and helped the poor to destroy their homes. In the process of dealing with the masses, I also deeply felt the turbulent but confused revolutionary enthusiasm. It seems that Guo Liang, who is surrounded by mountains and mountains, is eager to explore the way of struggle and the direction of progress. In 1919, Mao Zedong founded Xiangjiang Review in Changsha to spread and introduce new ideas. Guo Liang, who has been trying hard to explore the road of saving the country and the people, was struck by Mao Zedong’s article and soon became a loyal reader of Xiangjiang Review. In 1920, Guo Liang was admitted to Hunan No.1 Normal University, and met Mao Zedong by chance. From then on, he often asked Mao Zedong for advice on how to reform the society. Introduced by Mao Zedong, Guo Liang joined Xinmin Society, and then participated in Hunan Marxist Research Association organized by Mao Zedong, He Shuheng and Fang Weixia. In the practice of struggle, Guo Liang began to have a clear revolutionary ideal and struggle ideas, and firmly believed that nothing could be done without transforming the country.

In the winter of 1921, introduced by Mao Zedong, Guo Liang joined the Communist Party of China (CPC) and became one of the earliest party member in Hunan. When joining the party, Guo Liang made a generous statement: "Some people just give an empty mouth, and I, Guo Liang, are willing to give my head to the party." Guo Liang, who joined the Communist Party of China (CPC), finally belonged, and wrote a poem to express his feelings: "A trickle of water sinks into a huge stream, and it turns around without stopping; The back waves push the front waves and fly over the mountains to be free. " He compared his personal strength to a trickle, which, once put into the arms of the Party organization, converged into stormy waves and condensed into a majestic force of revolutionary struggle under the guidance of party flag.

"When will I wash away all my worries?"

After gloriously joining the Party, Guo Liang became more and more mature in thought, and more and more deeply realized that only by mobilizing millions of working people to work together can the action of saving the country have a steady stream of power. In the summer of 1922, after graduating from Hunan No.1 Normal School, Guo Liang immediately joined the revolutionary movement. In August of the same year, appointed by Mao Zedong, Guo Liang went to Yuezhou to carry out the work of Guangdong-Han railway labor movement. When he sailed down the Xiangjiang River to Dongting Lake, he was full of thoughts and couldn’t help chanting, "Xiao Shui, Xiang Shui, flows into the Yangtze River without a head." Long Jun sent me Dongting water, when will I wash away all my worries? " Guo Liang knew that the trip was bumpy and arduous, but he had no time to think about the severity of the difficulties, but immediately devoted himself to the fiery labor movement. On September 9th, Guo Liang organized and led a strike of 3,000 workers on the Guangdong-Han Railway, which shocked the whole country and opened the prelude to the first labor movement climax in Hunan. At the end of the same year, Guo Liang led the kindling of the workers’ movement to his hometown Tongguan. In the struggle, Guo Liang made good use of concise language to complain about the sufferings of ceramic workers, such as: "Digging clay bent his waist, pushing clay bowed his back, burning kiln goods burned his heart, making kiln goods worn his hand, and selling kiln goods lost his leg." In a few words, the injustice of the poor life of ceramic workers for generations was revealed, which aroused the workers’ resonance, condensed the struggle force, led the ceramic workers to resist the so-called "kiln door tax" and organized the establishment of the Tongguan ceramic trade union. On the day when the Tongguan Ceramics Trade Union was established, the Hunan District Committee of the Communist Party of China sent a pun couplet. The first part is "Don’t say that loose sand can’t make a great instrument", and the second part is "You should know that soil can turn into gold".Highly praised Guo Liang for leading generate, a ceramic worker.

In leading the Guangdong-Han railway workers’ strike, the pottery workers’ struggle against taxes and taxes, and the Changsha workers’ struggle against imperialism and feudal warlords, Guo Liang has increasingly demonstrated his ability to approach and inspire the masses. At that time, Bolshevik, the central theoretical publication, commented on Guo Liang: Guo Liang was the pioneer of Hunan workers’ movement. Anyuan in Jiangxi, Shuikoushan in Hunan, Changsha, Guangdong, Han and Zhuping in Hunan, Hubei and Jiangxi provinces, these local workers and other industrial professional workers all organized struggles under his direct and indirect guidance.

"Heroes have never bowed their heads since ancient times."

"Xiang water stirs up the hatred of the river, and the sword breaks the water and flows more. Although good and evil are reversed, heroes have never bowed their heads since ancient times. " This poem was sung by Guo Liang on the way to Wuchang after he was arrested by the enemy. It not only expressed his resentment of "the inversion of good and evil", but also showed his heroic spirit of being fearless and dying. In July, 1924, after Guo Liang was elected as the chairman of Hunan Anti-Imperialism Alliance, he wrote a lot of campaign articles. Under the careful organization of Guo Liang, Hunan once again set off an anti-imperialist climax. Guo Liang, who was at the forefront of the struggle, was wanted several times by Zhao Hengti, the warlord of Hunan at that time. In the face of the wanted notice, Guo Liang laughed it off without fear, and wrote a doggerel: "Zhao thief is persistent, a man looks like a wolf, killing with one hand and burning incense with the other, shouting autonomy and secretly communicating with the powers. If this cub is not removed, the people will suffer, and they will get a dog’s head and a pair of copper coins. Advise the police, don’t be fooled, help the tiger eat, and it will come to no good end. The notice is integrated, so remember to be detailed. " This limerick exposes the ugly face of reactionaries in laughing and cursing, and also points out the direction of struggle for the people in plain language. Under the leadership of Guo Liang and other comrades, anti-imperialist and patriotic activities in Hunan have become increasingly frequent and powerful. Facing the great revolutionary situation, Guo Liang and his comrade-in-arms Xia Minghan touched the scene and recited poems. Guo Liang recited: "One sword hangs on the bedside, and the GREAT GHOST kid comes in." Xia Minghan replied, "Kill all demons and level the world, and the mountains, rivers, the sun and the moon will be rearranged." The two revolutionary heroes expressed their aspirations with poems, and their determination to fight to the end jumped to the page.

In January 1928, dispatched by the CPC Central Committee, Guo Liang served as the secretary of the special committee of Hunan, Hubei and Jiangxi. Under the leadership of his organization, the party organizations in the border areas of Hunan, Hubei and Jiangxi provinces have been restored and developed. On March 27th, Guo Liang was arrested in Yueyang because of a traitor’s informer, and was executed secretly by the reactionary authorities in the early morning of 29th. Before his execution, he wrote a cone-shaped suicide note to his wife, who is also a native of communist party: "Can Ying, my love: Bright running around, homeless and stateless. I’m done. Hope to be kind and caress my son to follow my ambition. This is awkward. " This touching suicide note not only expresses deep attachment to family members, but also expresses infinite expectations for future generations to continue their struggle.

Luo Zhengxiang, a famous expert in cardiothoracic vascular surgery in China, developed the "China Heart" valve to lead the Institute of Cardiology to the world.

Video shooting/video editing: Liang Xuhao

Luo Zhengxiang, reporter Liang Yihao, photo

[Guangdong famous doctor who has been a doctor for 70 years]

Jinyang. com reporter Feng Xixi correspondent Yue Weixin Zhang Lanxi Zhang Lingling Yuting

Professor Luo Zhengxiang, 93, is a famous expert in cardiothoracic and vascular surgery in China. He used to be the president of Guangdong Provincial People’s Hospital and the director of Guangdong Institute of Cardiovascular Diseases. From a handsome young boy to a white-haired old man today, years have left traces, but he can never change the "passion" in his heart-"saving lives" is his lifelong pursuit.

Under his leadership, Guangdong took the lead in establishing the Institute of Cardiovascular Diseases in China, and its reputation is still far-reaching. This famous cardiovascular expert also won the honor of "Outstanding Contribution Award of China Cardiothoracic Surgery".

The "best student" was admitted to medical college.

Luo Zhengxiang, 93, has gray hair, but his figure is straight. He is still a handsome elder in a suit. His thinking is very clear. When he is free, he watches movies and listens to classical music. When he goes out, he takes a mobile phone and "scans the code to pay" like a young man. He is a "grandfather". This "post-90 s" grandfather has made outstanding contributions to the development of cardiovascular disease in China.

In 1947, Luo Zhengxiang did not study business or economics as expected by his father. "When I was a child, I loved reading history books and wanted to be a hero. At that time, the best students could be admitted to medical school, so I went after the hardest." With an indomitable spirit, he successfully passed the West China University of Medical Sciences.

In 1954, Luo Zhengxiang came to work in Guangdong Provincial People’s Hospital, and chose the most difficult and complicated major in the medical field at that time-cardiac surgery. Since then, he has embarked on a journey of "heart" for more than half a century.

Cardiac surgery was difficult to start in China at that time. But Luo Zhengxiang never gave up his research on heart disease-heart surgery is extremely demanding, starting with the most basic hemostasis practice. The great blood vessel was accidentally broken and the blood was shocking. Luo Zhengxiang looked at the shadowless lamp, pressed it, pressed it, pinched it, and stitched the wound with a big curved needle. He was calm and calm for a few times: OK. The valves are stitched one by one, and repeated actions are done over and over again, which is simple and boring. 1 hour, 2 hours … Some doctors have been standing on their legs and looking at them, but Luo Zhengxiang is staring, unhurried and meticulously crafted.

"I used to have surgery and the conditions were very bad. Eating a dollar at noon is simple; There is no air conditioning in the operating room. Everyone is sweating after the operation and can only drink more water after the operation. " Luo Zhengxiang said that although the conditions are difficult, everyone can work together with Qi Xin. "The director of the department takes the lead in suffering, and the doctors and nurses will follow suit. This is a kind of atmosphere and a kind of culture."

The first generation of artificial biological heart valve in China has been developed.

In 1974, after visiting Beijing, Shanghai and Guangzhou, Argentine cardiovascular experts decided to invite Guangdong experts to study cardiovascular technology in Argentina. On March 16th, 1974, a technical team organized by the Ministry of Health, mainly from Guangdong Provincial People’s Hospital (Xiang Xiangyao, Luo Zhengxiang, Chen Chuanrong, Wei Wanchang, Chen Zhiming, Wang Tailai and Jin Si Lan from the First Affiliated Hospital of Sun Yat-sen Medical College) went to Argentina for a one-year medical investigation. This year’s study was fruitful, and Luo Zhengxiang and his party brought back advanced valve technology. In 1977, Luo Zhengxiang and Cai Zengxin went to an Italian hospital in Argentina again to study heart valve technology. In 1975, the first domestic aortic valve replacement was successfully implemented, and the first domestic pediatric valve replacement was successfully implemented in the same year …

In the 1970s, rheumatic heart disease and rheumatic fever prevailed in southern China, but for these patients who need valve replacement, heart valves need to be imported, which is expensive and few people can afford it. Luo Zhengxiang and his colleagues are determined to make Chinese’s own heart valve. In 1976, Guangdong Institute of Cardiovascular Diseases set up a research room for artificial heart biological valves, and then cooperated with Australian medical expert Dr. Zhang Renqian to set up Pacific Biological Products Company in Huangpu District of Guangzhou with full reference to international standards to develop and produce artificial heart valves. In 1977, the first generation of artificial biological heart valve in China, Guangdong Type I, was developed and applied in clinic, taking the lead in the perioperative management of cardiac surgery and the application of intra-aortic balloon counterpulsation in critical heart surgery. In 1987, Guangdong II artificial heart biological valve was successfully developed, and in 1988, the artificial mechanical heart valve was successfully developed in cooperation with Australian experts and applied in clinic. Domestic valves greatly reduce the cost of patients’ surgery and shorten the gap between cardiothoracic surgery in China and advanced countries in the world.

3. Lead the Institute of Mind Research to break through difficulties and create brilliance.

In 1958, Guangdong Provincial Institute of Thoracic Diseases was established in Guangdong Provincial People’s Hospital. For various reasons, the development of the institute was quite tortuous. On August 7th, 1978, Guangdong Provincial Party Committee agreed to rename Guangdong Thoracic Disease Research Institute as "Guangdong Cardiovascular Disease Research Institute", and the Ministry of Health listed Guangdong Cardiovascular Disease Research Institute as one of the three key cardiovascular disease research institutes in China (Beijing, Shanghai and Guangdong).

In this way, the Guangdong Institute of Cardiovascular Diseases was established, but how to go next is a problem that Luo Zhengxiang has to face. Now, 93-year-old Luo Zhengxiang goes back to the Institute every day to see this old place where he has been "cultivating" for decades. Every time he walks past the entrance of Dongchuan Road, Guangzhou, he will think of the difficulties of that year: "The Institute had no funds at first, and we ran to the cement factory to find the cement. I wear leather shoes to the construction site every day to supervise the work. After that, I change my clothes and go back to the operating room for surgery. " In this way, with the concerted efforts of everyone’s Qi Xin, the Institute of Mind Research has grown up slowly.

Today, it has gone through 61 years. Over the past 61 years, the Institute has trained a large number of experts for the country, treated tens of thousands of patients and laid the foundation for the prevention of cardiovascular diseases. Created countless national firsts, first cases, and even world firsts.

Young doctors love to chat with Luo Zhengxiang, and he is also willing to communicate with young people. He said that he likes to chat with patients when he sees a doctor, and it is easier to build trust when he gets familiar with each other. "When you are a doctor, you must be dedicated to the patient and do everything for the patient; I have been a doctor for decades, and some patients have not been saved, but no one has ever made trouble, because they all know that I am saving with my heart. Whether the doctor is careful or not can be seen by patients and their families. "

[famous doctor said]

When you are a doctor, you should devote yourself to the patients.

When you are a doctor, you should be dedicated to the patient and do everything for the patient; I have been a doctor for decades, and some patients have not been saved, but no one has ever made trouble, because they all know that I am trying to save them.

Immune aging that cannot be underestimated: old age may lead to ineffective vaccines.

Original Zhao Bei Ten-Point Science

Because of the aging immune system, vaccines are less effective for the elderly. Scientists believe that it is more important and more widely used to develop drugs that can enhance the immune function of the elderly than to develop vaccines for the elderly.

Along with skin aging, there is also the immune system. | Figure worm creativity

Author | Doctor of Immunology, Zhao Bei

Recently, many deaths caused by influenza vaccine in Korea have attracted attention. As of October 31st, the death toll rose to 83, of which 71 were over 70 years old (accounting for 85.5%). In addition to the possible quality problems of the vaccine itself, it also reminds us of the fact that the role of the vaccine for young people and the elderly is different.

This is also a difficult point in the development of COVID19 vaccine.

Increasing age, and aging immune system

As people get older, we experience a series of physical changes, such as hearing loss, skin relaxation, joint injury and so on, and even the vitality of the immune system gradually decreases. This phenomenon is called "immune aging". This is also the reason why the elderly have become the main targets of infection and death in Covid-19.

In the face of the out-of-control epidemic in COVID-19, USA, and the emergence of the second round of epidemic peak in Europe, vaccine research and development is in full swing in various countries, which is expected to be a life-saving straw to reverse the situation.

However, vaccines, a means of "actively mobilizing the human immune system to prevent real virus attacks", are usually far less effective in the elderly population-the immune response of the elderly to vaccines is often weaker. That is, the immune system of the elderly is more difficult to be mobilized by vaccines.

This means that vaccines may not protect those who need protection most.

So, how does the immune system age?

Our bodies are naturally resistant to most pathogens. Although the environment is full of pathogens, we still live well most of the time.

The human immune system is divided into innate immunity and acquired immunity. The former is universal immunity. When the body encounters foreign objects (such as skin and mucous membrane), innate immunity will respond quickly. However, although it responds quickly, its ability is limited and it is often broken. For example, when it meets Covid-19, it can’t hold on.

The latter is the acquired immunity of the body, that is, for some pathogens that have not been seen before, the body must first fight with it and learn from it before it can gain immunity to it. The power of acquired immunity is very powerful. As long as the body can withstand the attack of pathogens in "learning" and meet the same pathogens in the future, it will not be a problem at all. For example, infectious diseases such as smallpox and chickenpox, if you get it once, you will generally not get it again.

When the body is invaded by foreign pathogens, such as viruses, innate immunity and acquired immunity will cooperate to resist.

In the innate immune system, immune cells, such as phagocytes and natural killer cells, will recognize or even devour the virus first, and secrete a large number of cytokines to summon more immune cells with different functions to join the battle. Some of these cells, such as phagocytes and dendritic cells, will also transmit the antigens of these viruses (substances that can cause antibody production) to the subsequent T cells and B cells, which are representatives of acquired immune cells.

T-cells and B-cells (shown here as antibodies produced by B-cells) are representatives of immune cells, and they are named after mature parts. The former is mature in thymus (English) and the latter is mature in bone marrow (English). Both are star immune cells. | Figure worm creativity

These two kinds of cells can not only produce antibodies and cytokines to quickly destroy the virus, but also form specific memory cells, so that they can respond quickly after encountering the same virus again.

When the immune system destroys the virus, immune cells will gather locally in the body, forming redness, swelling and heat pain, which is what we usually call inflammation. Proinflammatory factors secreted during this period, such as interleukin -1 and tumor necrosis factor α, can promote the elimination of pathogenic microorganisms, but excessive inflammation may lead to cytokine storms and even life-threatening. Another kind of anti-inflammatory factor, such as interleukin -10, can prevent excessive inflammation and maintain the balance of the body environment.

These factors together constitute our immunity.

And what will happen to our immune function as we get older? What is the impact on vaccine development?

Compared with young people, the immune aging of the elderly is mainly manifested in two aspects:

The initial number of T cells and B cells decreased. Vaccine mainly stimulates B cells to produce antibodies. Only when there are a large number of B cells with high diversity of receptors in the body, the greater the probability of recognizing antigens, and the targeted (directional) antibodies and memory B cells can be formed. -The decrease of B cells will undoubtedly weaken this effect.

Chronic low-grade inflammation is easy to occur after vaccination. The aging and necrotic cells in the elderly can not be removed in time, which will stimulate the immune system continuously, causing immune cells (such as macrophages) to continuously secrete pro-inflammatory cytokines, and the immune response cannot be terminated. The consequence is that the immune system can’t respond the next time the pathogenic microorganism attacks the human body, that is, immune dysfunction.

These lead to different effects of vaccines in the elderly and young people.

Vaccine research and development under "immune aging";

A special vaccine or an auxiliary drug to reverse aging?

For Covid-19, there are about 50 kinds of vaccines being tested in the world, but scientists are still not sure whether the vaccines are equally effective for the elderly.

One of the vaccines "mRNA-1273" being developed by Moderna, a biological company located in Cambridge, Massachusetts, USA, produced antibody levels similar to those of younger subjects in 40 subjects over the age of 56.

However, Pfizer and BioNTech, pharmaceutical companies located in Mainz, Germany, found in the first phase of the experiment that the antibody level induced by the vaccine "BNT162b2" was only half that of young people. It is certain that the antibody level produced by the elderly after vaccination is higher than that caused by the virus infection of their peers, but this is still not enough to explain whether the antibody induced by "BNT162b2" is enough to protect the elderly from the real virus attack.

Most of the vaccines being developed have elderly subjects, but more than half of the 18 latest candidate vaccines have no elderly subjects in clinical trials, which greatly increases the potential risks of vaccines to the elderly.

Some vaccines are being developed, which may have hidden dangers for the elderly. | Figure worm creativity

Facing the phenomenon of immune aging of the elderly, scientists are also actively looking for strategies.

Mainly includes the following two aspects:

(1) The first is how to enhance the immune response of the elderly induced by vaccines.

According to the experience in the research and development of influenza vaccine, the elderly are usually treated by increasing immune stimulating components (such as adjuvants) or increasing the dose of virus antigen to achieve the expected antibody level.

Other scientists have turned to developing drugs to enhance the immune system function of the elderly, that is, supplementing drugs at the same time of vaccination. This way aims to promote the rejuvenation of the immune system of the elderly, even reverse immune aging, and can also resist the virus more effectively when it is infected.

In the above two schemes, the research on reversing age, especially immune aging, has made some progress. In the past 20 years, scientists have found some key small molecular targets. One kind of anti-aging drugs acts on the protein molecule mTOR in the cell growth regulation pathway. Experiments show that inhibiting the expression of mTOR can prolong the life of Drosophila and even mice.

Joan Mannick, one of the founders of resTORbio, a biotechnology company in Boston, Massachusetts, USA, said that "mTOR participates in many biological regulation mechanisms, especially the process of human aging and organ dysfunction".

During his work at Novartis Institute in Cambridge, Massachusetts, Mannick published a study on mTOR protein in 2018, trying to answer the question "Can reducing the content of mTOR protein in the elderly improve the immune system function of the elderly?". 264 participants in the study received low-dose mTOR inhibitor or placebo respectively, and after six weeks, the infection rate of influenza virus and the effect of influenza vaccine were followed up. It was found that the number of people suffering from influenza in the elderly who received mTOR inhibitors decreased significantly, and the immune response caused by influenza vaccine was stronger.

Another study shows that mTOR inhibitor RTB101 can enhance the immune response of the elderly after coronavirus infection, and the elderly who receive mTOR inhibitor have lower coronavirus load and recover faster. At present, resTORbio is testing the preventive or therapeutic effect of RTB101 on Covid-19 infection in 550 elderly people over 65 years old in nursing homes.

In addition, at least four research teams are studying the therapeutic effect of rapamycin, another more mature mTOR inhibitor, on the elderly over 60 years old infected with COVID-19.

In addition, metformin, a drug for the treatment of type 2 diabetes, also inhibits the activity of mTOR protein. Clinical data from China and the United States show that diabetic or obese patients who take metformin have less symptoms of Covid-19 infection and lower mortality.

Carolyn Bramante, a researcher at the University of Minnesota in the United States, pointed out that people with diabetes and obesity show immune deficiency very similar to that of the elderly. At present, Bramante and his colleagues are conducting a study involving 1,500 people to explore whether taking metformin can prevent Covid-19’s infection or alleviate its symptoms. Although the mechanism is not clear, decades of clinical data show that metformin has high safety, can be used in children and even pregnant women, and the cost is very low, which are the advantages of metformin.

(2) The second key is how to avoid causing or how to terminate chronic inflammatory reaction.

Studies have found that losmapimod, an anti-inflammatory drug used to treat muscular dystrophy, can inhibit chronic inflammatory response and improve the body’s response when viruses or bacteria invade. A biological company in Cambridge, Massachusetts, USA recruited 400 volunteers to verify the therapeutic effect of losmapimod on patients with COVID-19. The drug may be able to treat symptoms such as respiratory failure after Covid-19 infection, thus saving patients’ lives.

Many scientists say that it is more important to develop drugs to enhance the immune function of the elderly than to develop COVID-19 vaccine for the elderly, and the latter is more universal, which can improve the protection effect of influenza vaccine, COVID-19 vaccine and even other vaccines in the future. A deep understanding of immune aging and its regulation mechanism and the development of related drugs will also have far-reaching implications for the treatment of other diseases such as diabetes and cancer.

In short, although there are always difficulties in vaccine development, known or unknown, scientists have been working hard and believe that methods will always be found.

(Editor Gao Peiwen)

Original information:

Cassandra Willyard, Nature vol 586, 15.10.2020

Reference information:

1. Anderson E. J.et al., N. Engl. J. Med., 2020

2. Walsh E. E. etal., Preprint at medRxiv https://doi.org/10.1101/2020.08.17.20176651 (2020)

3. Helfand B. K. I. et al., JAMA Intern. Med., 2020

4. Mannick J. B. et al., Sci. Transl. Med., 2020

5. Luo P. et al., Am. J. Trop. Med. Hyg., 2020

6. Bramante, C. et al., Preprint at medRxiv https://doi.org/10.1101/2020.06.19.20135095(2020)

7. Vukmanovic-Stejic M. et al., J. Allergy Clin. Immunol., 2018

The article was published by "Ten Points of Science" (ID: Science _ 10) WeChat official account, please indicate the source.

Original title: "Immune aging that cannot be underestimated: old age may lead to ineffective vaccines"

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After 90, the doctoral supervisor sent 60 SCI papers in five years, which led to doubts and the research group responded.

  Recently, Hu Yue, associate professor and doctoral supervisor of Huazhong University of Science and Technology, has caused a heated discussion because he published 60 SCI papers in five years.

  According to the teacher’s personal homepage of Huazhong University of Science and Technology, Hu Yue received a bachelor’s degree in applied chemistry from East China University of Science and Technology in 2012 and a doctorate in chemistry from Edinburgh University in 2016.

  In the same year, she joined Wuhan Photoelectric National Research Center of Huazhong University of Science and Technology, and has been engaged in theoretical and experimental research of photovoltaic materials for solar cells for a long time.

  In self-introduction, Hu Yue mentioned that in the past five years, she has published more than 60 SCI papers, including 21 papers by the first correspondent, including 1 paper by Science, 1 paper by Joule and 1 paper by Advanced Materials. At present, there are 2 highly cited papers on ESI.

  Nine groups of journalists found that in the statistical table of journal impact factors released in June this year, the impact factor of Science was 47.728, that of Joule was 41.248, and that of Advanced Materials was 30.849. Impact factor refers to the frequency with which articles in a periodical are cited in a specific year or period. Generally speaking, the higher the impact factor, the greater the influence of the journal.

  Some netizens said that before Hu Yue joined Huazhong University of Science and Technology, there were only four papers by the first author, and one paper was output on average one month after joining the company, and his paper was suspected of "irrigation".

  "Our teacher didn’t do anything wrong, but the mistake was too much exposure." On the afternoon of December 13th, han hongwei, the leader of Hu Yue’s research group and professor of Huazhong University of Science and Technology, responded to the reporter.

  "Our research group has a large number of people and published many articles, which has caused some misunderstandings." Han hongwei said.

  The leader of the research group responded: The mistake is that there is too much exposure.

  "We didn’t expect the heat to be so high, and this matter was misinterpreted." Han hongwei said.

  His office is next door to Hu Yue. On December 13th, he answered the phone all afternoon and walked in a hurry. Referring to Hu Yue, he said angrily, "Our teacher didn’t do anything wrong, but the mistake was too much exposure."

  On December 8th, a post-90s doctoral supervisor was often recognized as a "teacher elder sister"! The introduction is very eye-catching! The article was reprinted by many media, allowing Hu Wei to enter the public eye. While gaining praise, Hu Yue’s resume also sparked heated discussion.

  In the article, Hu Yue said that her grandfather graduated from Zhejiang University with a bachelor’s degree and a master’s degree, and she has been engaged in chemical-related work. Her interest in scientific research was enlightened by her grandfather. In 2008, Hu Yue was admitted to the School of Chemistry and Molecular Engineering of East China University of Science and Technology. In 2009, she joined the team of Academician Tian He and participated in the national innovative experimental program for college students to carry out research on "dye-sensitized solar cells". Therefore, some netizens speculated that Hu Yue relied on his grandfather to obtain academic resources.

  On December 14th, Hu Yue responded in an interview with China Science News that his grandfather was a retired engineer of former Wuhan Chemical Industry Bureau, not an academician of Internet communication. According to public reports, Hu Yue scored 626 points in the college entrance examination that year, ranking first among Hubei candidates admitted by East China University of Science and Technology. With such good grades, she joined the Department of Science and Technology Excellence of East China University of Science and Technology, and had the opportunity to choose Professor Tian He as her tutor.

  On the teacher’s personal homepage of Huazhong University of Science and Technology, Hu Yue briefly mentioned that in the past five years, she has published more than 60 SCI papers, including 21 first/correspondent papers. Including 1 science, 1 Joule, 1 advanced materials, 2 advanced energy materials, 2 advanced functional materials, 1 ACS energy letter and 1 energy & environmental science. At present, Google Scholar has cited more than 1,800 times, with an H index of 24, and 2 papers have been selected as highly cited papers in ESI.

Hu Yue's research field. Network screenshot

  Hu Yue’s research field. Network screenshot

  Han hongwei explained why the number of Hu Yue’s articles is as high as 60: "As a teacher of the research group, we will collectively take a group of students to give guidance from different angles and different professional backgrounds. If the teacher contributes, we will write his name in." He added that apart from the first author, co-first author and correspondent, other teachers are only participants, and their contribution may be only 1% or 10%, and they are not responsible for the article.

  According to WeChat official account, the official of Huazhong University of Science and Technology, at present, Hu Yue and Professor han hongwei have jointly trained five doctoral students and five master students independently. Three master students have graduated, two have entered Huawei and one has gone to Zhejiang University for further study.

  "Our research group has a large number of people and published many articles, which has caused some misunderstandings." Han hongwei said.

  He was promoted to associate professor in two years and became a doctoral supervisor in three years.

  "Young" and "excellent" are Hu Yue’s most conspicuous labels. The short film "Chasing the Light — — In Hu Yue, Hu Yue said: "I am an associate professor and doctoral supervisor born in the 1990s. When I first returned to China, many students were even older than me."

  During the undergraduate course, she studied with Professor Hua Jianli of East China University of Science and Technology and Academician Tian He. In the representative papers listed by Professor Hua Jianli in official website, East China University of Science and Technology, Hu Yue’s name appeared in the author list of six papers, and the publishing time was from 2014 to 2017.

  In 2012, after graduating from Hu Yue University, he applied for a full scholarship with excellent results and entered the University of Edinburgh to continue solar cell research. In 2016, Hu Yue received his Ph.D. and joined Huazhong University of Science and Technology through the postdoctoral talent introduction program.

  According to the upstream news report, there are four papers published by Hu Yue in 2016, which are neither the first author nor the correspondent author, and of these four papers, only one is more valuable, but it is not the top publication. Therefore, some netizens think: "At this level, if the postdoctoral experience is not gilded, it is difficult to get a teaching position in a school like Huake."

  In this regard, Hu Yue said in an interview with China Science News that during her doctoral period, she published more than 10 papers, among which 6 were first authors or co-first authors. After graduating from Ph.D., she first entered Huazhong University of Science and Technology as a postdoctoral fellow and stayed at school after leaving the station.

  Official website of Huazhong University of Science and Technology shows that Hu Yue went to Oxford University, London Imperial College London and Lausanne Federal Institute of Technology for cooperation and exchange for one or three months during his doctoral studies.

  After entering Huazhong University of Science and Technology, the number of articles published by Hu Yue increased significantly. The reporter found in Google Academic Search that Hu Yue published 13 papers in 2017.

  In 2018, she and associate professor Rong Guangguang of Huazhong University of Science and Technology and Dr. Mei Anyi published a paper as the co-first author, which was published in Science magazine, and the project also won the support of major research plan integration projects and key projects of the National Natural Science Foundation.

  In the same year, Hu Yue was promoted to associate professor and became a doctoral supervisor in 2019.

  The office door is covered with cartoon images.

  At five o’clock on the afternoon of December 13th, the building of Wuhan Optoelectronic National Research Center in the east campus of Huazhong University of Science and Technology was full of busy students.

  In the corridor, five students around the round table discussed the group work fiercely. A black boy wearing headphones came out of the laboratory and stared blankly out of the window. There were four graduate students at the corner of the stairs to define the division of labor for the next project presentation.

  Hu Yue works on the eighth floor. In a row of offices, hers is the most special. The gray door is covered with the image of opening, an orange cat sticker is stuck by the door, and the stills of Naruto are skewed in the center, with two molecular formulas sandwiched between them.

Hu Yue's office. Figure/Nine School News Ma Jieying

  Hu Yue’s office. Figure/Nine School News Ma Jieying

  The reporter found that Hu Yue had only one project practice class recently.

  Liu Yilin (pseudonym), a graduate student at the School of Optoelectronic and Information, Huazhong University of Science and Technology, said that Hu Yue spends most of her time in the laboratory, but recently, because of her graduation thesis defense, she rarely appears in this building. "I am not here these days." Liu Yilin said.

  Liu Yilin’s impression of Hu Yue is "tenderness". Because they are not in the same research group, there is not much communication. The only communication between him and Hu Yue was when he defended his graduation thesis last year. At that time, as soon as he showed the results of his paper, Hu Yue asked a question about energy management, but Liu Yilin’s research direction was different from this. He didn’t answer it. "I was very nervous at that time, but the teacher was very gentle and didn’t answer it."

  Opposite Hu Yue’s office is the student office, where several graduate students work. The computer screen of the girl sitting at the door is covered with experimental pictures, and there are unfinished English papers in the document.

  A student from other research groups told reporters that she had read online queries and hoped not to interview Mr. Hu. "Teacher Hu is usually very kind to us."

Regarding the prevention of influenza, WHO’s latest recommendation of influenza vaccine strains in 2024-2025.

Foreword

Influenza virus can cause seasonal influenza, and may even cause a pandemic outbreak. Influenza virus is a negative-strand RNA virus with complex classification, numerous subtypes and easy mutation. At present, it is recognized that the best way to prevent influenza is vaccination. In order to ensure the effectiveness of the vaccine, the World Health Organization (WHO) updates the composition of the vaccine strain every year.

Changes of influenza vaccine strains in the northern hemisphere in 2024-2025

In order to keep the vaccine effective, it is necessary to update the components of influenza virus vaccine regularly. After analyzing the global influenza virus epidemiology, etiology and vaccine serology, WHO announced the recommendation of influenza vaccine components in the northern hemisphere from 2024 to 2025 on February 23, 2024.

?

Trivalent chicken embryo culture vaccine

an A/Victoria/4897/2022 (H1N1)pdm09-like virus

an A/Thailand/8/2022 (H3N2) -like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Trivalent cell culture or recombinant protein vaccine

an A/Wisconsin/67/2022 (H1N1)pdm09-like virus

an A/Massachusetts/18/2022 (H3N2)-like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Tetravalent chicken embryo and cell culture or recombinant protein vaccine

The following components are added on the basis of trivalent vaccine

a B/Phuket/3073/2013 (B/Yamagata lineage)-like virus

Since March 2020, the naturally occurring B/Yamagata virus has not been confirmed. WHO thinks that it is not necessary to use B/Yamagata virus as a component of influenza vaccine, and it should be removed from the component of influenza vaccine. Where tetravalent vaccine is still used, the composition of B/Yamagata line is consistent with the previous recommendation.

Comparing the composition of influenza vaccine in the northern hemisphere from 2023 to 2024, it was found that the change of composition was mainly due to the difference of H3N2 virus strains:

Vaccine types

2023-2024

2024-2025

Trivalent chicken embryo culture vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Thailand/8/2022 (H3N2) -like virus

Trivalent cell culture or recombinant protein vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Massachusetts/18/2022 (H3N2)-like virus

Recombinant antigen is the key material for vaccine research.

In influenza virus-related vaccines, drugs and even diagnostic reagents, key target antigens have played an important role. In the following table, we have sorted out the information of HA, NA and NP proteins.

albumen

function

app; application

HA

(hemagglutinin)

The sialic acid receptor on the host cell membrane binds to help the virus envelope fuse with the host cell membrane; Coagulation

Basic research on influenza

Influenza vaccine research and development

Development of anti-hemagglutinin antibody

Study on virus detection reagent

NA

(neuraminidase)

Hydrolyze sialic acid receptor to promote the release of mature virus particles

Research and development of antiviral drugs

Basic research on influenza

Influenza vaccine research and development

Antibody development

Study on virus detection reagent

NP

(nuclear protein)

Combine with influenza genetic material and participate in virus gene replication, transcription and translation; Maintain the stability of virus gene

Research and development of antiviral drugs

Basic research on influenza

Antibody development

Diagnostic product development

The recombinant antigen of influenza vaccine strain can be used in all aspects of vaccine development, such as vaccine content detection, vaccine biological titer detection and toxicological experimental research. Using recombinant antigen for ELISA detection, we can analyze the levels of serum total antibody and neutralizing antibody after vaccination, and use recombinant protein as control to detect the vaccine content.

The results of detecting the serum antibody level of mice immunized with vaccine by recombinant influenza HA protein (image from Andersen, et al.)

Influenza vaccine strain-related antigens are available in stock.

Yiqiao Shenzhou continues to pay attention to the research progress of influenza vaccine, and has built a relatively complete influenza virus research reagent library. It has been online to recombine some proteins of HA, NA and NP of the northern hemisphere influenza vaccine strain in 2024-2025, and it is available from stock. Order it now!

Consultation is polite!

After checking the information correctly, you can get a 35 yuan Luckin Coffee voucher.

Scanning code to understand the recombinant antigens related to components of influenza vaccine strains from 2024 to 2025;

references

[1]https://www.who.int/publications/m/item/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season

[2] Andersen, et al. Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief.[J]. Frontiers in Immunology.2021.747032.

[3] Bangaru S , et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface[J]. Cell, 2019.

[4] Kim M, et al. Inhibition of infection virus internalization by (-)-Epigallocatechin-3-gallate. [J]. Antiviral Research, 2013,100 (2): 460-472. Continue to slide to see the next one.

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