Shanghai Customs released the first batch of imported Pfizer Covid-19 therapeutic drugs.

The reporter learned from Shanghai Customs that at 22: 30 on March 17th, 21,200 boxes of imported Covid-19 therapeutic drug "Naimatvir/Ritonavir Tablets" (Paxlovid) were cleared by Shanghai Waigaoqiao Free Trade Zone, and all the import clearance procedures were completed, and they were rushed to the national anti-epidemic front line. This is the first import of this drug in China after it was included in the latest version of COVID-19’s diagnosis and treatment plan.

On February 11th, 2022, according to the relevant provisions of the Drug Administration Law and the special drug approval procedures, National Medical Products Administration conducted emergency review and approval, and conditionally approved the import registration of the combined packaging (Paxlovid) of nematevir tablets and ritonavir tablets in Covid-19, Pfizer. On March 15th, the main points of the revision of novel coronavirus Diagnosis and Treatment Plan (Trial Ninth Edition) issued by the National Health and Wellness Commission showed that the specific anti-Covid-19 drugs of Naimatevir Tablets/Ritonavir Tablets (Paxlovid) approved by National Medical Products Administration were written into the diagnosis and treatment plan.

Hu Xiaoming, deputy director of the General Department of Shanghai Customs, said that the goods were imported from Pudong Airport. They connect with enterprises in advance to understand the import situation of goods, formulate and start the whole customs clearance guarantee plan, and guide enterprises to adopt the "declare in advance" model. After the goods arrived at Pudong Airport, they were immediately removed and transferred to Waigaoqiao Free Trade Zone, which provided valuable time "ahead of schedule" for enterprises to declare imports and distribute shipments.

After the customs in the bonded area "receives the stick", a green channel is set up at the business site to ensure the safe and convenient customs clearance of goods. In view of the strict requirements for the storage environment of this batch of drugs, after receiving the application for making an appointment for inspection from the enterprise, the customs of the bonded area appointed customs officers to go to the enterprise to carry out warehousing inspection under the premise of doing a good job of safety protection, and complete the on-site inspection according to the inspection instructions to realize the "zero waiting" for customs clearance.

Geng Jing, head of the Second Division of Customs Comprehensive Business in the Bonded Zone, told the reporter: "This batch of goods is relatively large. We give full play to the function of the logistics distribution center in the special customs supervision area, and help enterprises to reasonably arrange the batch exit and the corresponding transportation plan according to the actual situation and demand, and provide all-weather customs clearance guarantee, so as not to delay drugs for one second."

Policy "combination boxing" boosts confidence and stimulates vitality. The real estate market in China continues to pick up.

CCTV News:In May, many departments launched a "combination boxing" of real estate policies, and introduced a series of optimization and adjustment policies, including the minimum down payment ratio to 15% and the cancellation of the lower limit of commercial loan interest rates. Many cities followed suit, including lowering the threshold, lowering the down payment, adjusting interest rates, and "swapping old for new" policies. Now, one month has passed, what is the effect? On June 23rd, we will pay attention to the recent changes in the real estate market. In Beijing, after visiting the new housing market, the reporter found that with the continuous release of the policy effect, the number of people looking at the house has increased significantly, and the amount of online and offline consultation has greatly increased.

In the sales office of a new house project in Beijing’s South Fourth Ring Road, the reporter saw that many prospective buyers were learning about the real estate situation from the sales staff. The reporter made a rough statistics at the scene. Within an hour, the sales office hall received more than 20 groups of people who came to see the house. Sales staff told reporters that compared with before, the number of people who came to see the house recently increased significantly.

According to the statistics of relevant institutions, influenced by a series of policy optimization and adjustment recently, the number of consultations and offline visits of many new housing projects in Beijing has increased significantly, and the number of visits of some projects has increased by 70% compared with the beginning of the year. At the same time, influenced by the optimization of the purchase restriction policy outside the Fifth Ring Road, Shunyi, Changping, Daxing, Fangshan, Tongzhou and other districts have now become the best areas in Beijing’s new housing market. According to the latest data released by the Beijing Municipal Commission of Housing and Urban-Rural Development, from May 17 to June 17 this year, 3,147 sets of new commercial residential buildings were signed online in Beijing.

Wang Ruimin, an associate researcher at the Institute of Market Economy of the State Council Development Research Center, said: "I think confidence in the market is a great boost, which means that most buyers who have some wait-and-see mood also actively enter the market, which will also drive other residents to have confidence, and the market transaction heat will increase and become active."

However, after visiting real estates in other regions, the reporter found that not all real estates have seen a substantial increase in the number of visits at present, and there is also a phenomenon of uneven hot and cold between different real estates. The real estates suitable for just-needed and improved needs are obviously more attractive to buyers. In addition, because Beijing’s current policy has only lowered the interest rate of provident fund loans, it has not followed up by lowering the down payment and lowering the interest rate of commercial loans. Therefore, the new housing market is more wait-and-see than the second-hand housing market, and many buyers are still waiting to see more policies.

Hangzhou: Second-hand housing transactions increased significantly.

On May 9, Hangzhou announced the cancellation of the purchase restriction. It has been more than a month since then. What is the effect of the policy? After the reporter visited, it was found that the volume and volume of local second-hand housing belts have increased in different ranges.

Not long ago, Zhejiang Branch of the People’s Bank of China issued the first home down payment and loan interest rate policy. The down payment ratio was not less than 15%, and the first home loan interest rate dropped to 3.25%, both of which were at historical lows, greatly boosting the just-needed willingness to buy a house. Xiao Zhang, who has worked in Hangzhou for four years, has been busy looking at houses in various intermediaries recently after learning that the local mortgage interest rate has dropped sharply.

Statistics from relevant intermediaries show that in May, 8254 sets of second-hand houses were sold in Hangzhou, up 8.3% year-on-year, and the turnover of second-hand houses exceeded 8000 sets for three consecutive months.

Shangguan Jian, dean of RealData Hangzhou Branch, said: "The full liberalization of purchase restrictions has significantly reduced the cost of buying a house, which has played a significant role in helping the whole market."

The reporter noted that the Hangzhou property market, stimulated by the New Deal, recently saw an increase of 20% and 30% in the daily average number of second-hand houses and the number of people who booked rooms compared with those before the New Deal.

He Chenyu, deputy director of the Real Estate Development Department of Hangzhou Housing Security and Real Estate Administration, said: "We have noticed that the leading indicators of the relevant markets are at a high level in the past two years. According to this, it is predicted that the policy follow-up will still have a certain lasting effect and the market will continue to pick up." 

Wuhan: Market confidence has been further enhanced.

Wuhan is the first city in China to announce the reduction of the lower limit of mortgage interest rate after the "New Deal of May 17th". In the past month, with the successive implementation of various real estate policies, the activity of Wuhan property market has been significantly improved, consumers’ expectations have improved, and market confidence has been further enhanced.

In a sales office in Hanyang District, Wuhan, Mr. Xiang is consulting about buying a house. With the new house purchase measures, the down payment threshold is lowered, and he can now replace the same down payment with a larger house.

At present, Wuhan’s provident fund loan interest rate, commercial loan interest rate and minimum down payment ratio are all at historical lows. Affected by this, in the past month, the average daily transaction volume of new houses in Wuhan was nearly 200 sets, which was nearly 20% higher than that in April and nearly 50% higher than that in the first four months of this year.

Compared with new houses, the activity of the second-hand housing market in Wuhan has also increased obviously, and the transaction volume of second-hand housing has exceeded that of new houses for three consecutive months. Many intermediaries told reporters that in the past, the intermediary commission was mostly borne by the buyer, but now it is borne by the seller or shared by both parties, which shows that the market is shifting from the seller’s market to the buyer’s market.

Experts said that with the release of the real estate policy effect, I believe that the follow-up will further boost the market.

Pan Shibing, president of Hubei Real Estate Association, said: "The policy has been implemented for more than a month, and I think the effect is quite obvious. The whole consumer’s expectation has improved, and the market confidence has obviously recovered, including the obvious increase in the whole sales volume. In the next step, the recovery of the entire real estate market will be more obvious, and the confidence of real estate enterprises will be more obvious. "

Shenzhen: The policy effect is still being released.

After the announcement of the "5.17 New Deal for the Property Market", Shenzhen also actively followed up and lowered the minimum down payment ratio and the lower interest rate limit of individual housing loans. The reporter recently visited and found that it has been more than a month since the release of the policy. The current activity of the Shenzhen property market has improved and the policy effect is being continuously released.

Recently, the reporter learned in a real estate agency store in the central area of Shenzhen that since the implementation of the New Deal, the transaction volume of second-hand houses in this store has increased by 52% month-on-month, and the enthusiasm of customers who just need to buy a house for the first time has been significantly improved, especially the number of customers who come to see the house for the first time through online appointment has increased by more than 20% compared with before, among which the growth of customers who just need to buy a house is particularly obvious.

In the interview, many buyers said that the landing of the new policy has reduced the down payment of buyers. Under the condition of limited budget, buyers now have more choices.

The reporter learned from the Shenzhen Real Estate Agency Association that after the introduction of the New Deal, the policy effect of low down payment and low interest rate continued to be released, which not only drove some customers who just needed to enter the market, but also improved the activity of improved housing transactions.

According to relevant statistics, from May 18th to June 17th, 2286 sets of new houses were sold in Shenzhen, up by 3.96% over the month before the New Deal. A total of 4136 sets of second-hand houses were sold, up 2.86% from the month before the New Deal.

In 2019, the confidence in the development of the construction industry in our province increased in the later period of steady growth.

  2019In, the whole province focused on catching up and surpassing and the requirements of "five solidities" to overcome various adverse effects, and with the help of vigorously improving the business environment, the total output value of the construction industry was realized throughout the year.7883.88100 million yuan, a year-on-year increase10.7%The growth rate of output value ranks twelfth in the country. The comprehensive strength of construction enterprises has been greatly improved, the industrial structure of enterprises has become increasingly reasonable, and the added value of construction industry accounts for the whole province.GDPSpecific gravity reached9.6%The position of the construction industry as a pillar industry has been continuously consolidated.

 

  First, the overall production and operation of construction enterprises in the province is improving.

 

  oneThe output value of enterprises has increased steadily.

 

  2019In, the construction enterprises in the whole province (note: the following construction enterprises refer to general contracting and professional contracting enterprises) completed the total output value of the construction industry.7883.88100 million yuan, a year-on-year increase10.7%, down from the same period last year.3.6Percentage points. In which: the output value of construction project is completed.6910.58100 million yuan, a year-on-year increase10.9%, down from the same period last year.1.4Percentage points. Completion of installation project output value665.65100 million yuan, a year-on-year increase11.4%, down from the same period last year.12.5Percentage points. Other output value307.65100 million yuan, a year-on-year increase6.0%, down from the same period last year.40.9Percentage points.

 

 

  2The amount of new contracts signed this year has increased significantly.

 

  2019The total amount of contracts signed by construction enterprises in the province in.17973.34100 million yuan, a year-on-year increase17.7%, higher than the same period of last year.8.7Percentage points. In which: Contract amount carried forward from the previous year8275.77100 million yuan, a year-on-year increase16.0%, down from the same period last year.13.5Percentage points. New contract amount signed this year9697.57100 million yuan, a year-on-year increase19.2%, higher than the same period of last year.23.5Percentage points. The effective growth of newly signed contracts has provided effective support for the steady growth of construction production in our province throughout the year.

 

  threeThe growth rate of enterprise construction area has accelerated.

 

  2019In, the construction enterprises in the whole province realized the building construction area.35276.4610,000 square meters, a year-on-year increase.19.0%, higher than last year.ninePercentage points. Due to the unsaturated workload of some enterprises in this year’s construction, the growth of new construction area this year is weak, falling year-on-year4.3%.

 

  fourThe per capita labor productivity is increasing year by year.

 

  2019Construction enterprises with total qualifications in the province in.3255Households, year-on-year growth15.5%, net increase of enterprises this year.438Household; Average number of people in construction industry171.3Ten thousand people, down year-on-year.1.1%, down from the same period of last year.1.83Ten thousand people. With the decrease of the average number of enterprises and the continuous improvement of the level of mechanization in the industry, the per capita labor productivity of construction enterprises in the province has increased.46.09ten thousand yuan/People, an increase over the same period last year.4.96ten thousand yuan/People. The improvement of labor productivity provides a strong guarantee for the market competitiveness of construction enterprises in our province.

 

  fiveThe enterprise has a high prosperity and is optimistic about the future construction market.

 

  According to the annual prosperity index survey,2019The annual business climate index is the first quarter respectively.110.1%Second quarter111.6%Third quarter110.9%Fourth quarter112.8%The prosperity index in the fourth quarter was higher than that in the same period of last year.1.4Percentage points.2019The annual enterprise confidence index is the first quarter respectively.114.6%Second quarter115.2%Third quarter113.7%Fourth quarter115.0%The confidence index in the fourth quarter increased compared with the same period of last year.2.7Percentage points.

 

  Second, the structural characteristics of the province’s construction enterprises

 

  oneFrom the composition of output value, the output value of construction projects is dominant.

 

  2019Construction enterprises in the whole province realized the output value of construction projects in.6910.58One hundred million yuan, the proportion of engineering output value to the total output value is87.7%, higher than the same period of last year.0.2Percentage points. Completion of construction and installation project output value665.65One hundred million yuan, construction and installation engineering output value accounted for the proportion of the total output value is8.4%, unchanged from the same period of last year. Completion of other output values307.65One hundred million yuan, the proportion of other output value in the total output value is3.9%, down from the same period last year.0.2Percentage points.

 

 

  2In terms of industries, the housing construction industry occupies the first place

 

  2019In the province’s construction enterprises in, the housing construction industry achieved a total output value.4171.55Billion yuan, accounting for the total output value of the construction industry.53.0%, down from the same period last year.0.9Percentage points. The total output value of civil engineering and construction industry is realized.3184.68100 million yuan. Accounting for the total output value of the construction industry40.4%, higher than the same period of last year.2.2Percentage points. Including: railway, road, tunnel and bridge engineering construction industry completed.2488.11100 million yuan, accounting for the output value of all civil engineering industries.78.1%. The construction and installation industry has achieved total output value.367.95Billion yuan, accounting for the total output value of the construction industry.4.6%, down from the same period last year.0.9Percentage points. Building decoration and other construction industries realize total output value.159.70Billion. Accounting for the total output value of the construction industry2.0%, down from the same period last year.0.4Percentage points.

 

 

  threeIn terms of qualification level, super-grade and first-class enterprises occupy the main market share.

 

  2019In 2000, the province’s construction enterprises were middle-grade and first-class enterprises.494Home, accounting for all general contracting and professional contracting enterprises.15.2%, realize the construction industry output value.5471.19Billion yuan, accounting for the total output value.69.4%, higher than last year.2.2Percentage points. Secondary enterprise1769Home, accounting for all general contracting and professional contracting enterprises.54.3%, realize the construction industry output value.1847.88Billion yuan, accounting for the total output value.23.4%, down from the same period last year.0.1Percentage points. Level 3 and below enterprises992Home, accounting for all general contracting and professional contracting enterprises.30.5%, realize the construction industry output value.564.81Billion yuan, accounting for the total output value.7.2%, down from the same period last year.2.1Percentage points.

 

  fourIn terms of regions, Guanzhong is still the main force.

 

  The industrial structure of Shaanxi construction industry is still dominated by Guanzhong, supplemented by southern Shaanxi and northern Shaanxi.2019In, the construction enterprises in Xi ‘an, Tongchuan, Xianyang, Weinan, Baoji and Yangling in Guanzhong area completed the total output value of the construction industry.6737.55One hundred million yuan, accounting for the proportion of the province.85.5%, higher than the same period of last year.0.6Percentage points. Construction enterprises in Ankang, Hanzhong, Shangluo, Yan ‘an and Yulin in southern Shaanxi and northern Shaanxi have completed the total output value of the construction industry.1146.33One hundred million yuan, accounting for the proportion of the province.14.5%, down from the same period last year.0.6Percentage points. Among them, southern ShaanxithreeShizhan8.2%, northern Shaanxi2Shizhan6.3%. In terms of the total amount and growth rate of cities, Xi’ an has the highest proportion, accounting for the province’s output value57.3%, higher than the same period of last year.2.5Percentage points. Tongchuan has the lowest proportion, accounting for the province’s output value.0.6%, unchanged from the same period of last year. Tongchuan’s growth rate is the fastest21.7%, higher than the whole province.11Percentage points. Shangluo growth rate-12.3%The growth rate is the lowest, lower than that of the whole province.23Percentage points.

 

  fiveFrom the perspective of domestic and foreign markets, the share of output value of enterprises in our province in other provinces has been continuously improved.

 

  2019Enterprises in our province completed output value in other provinces in.2539.36100 million yuan, a year-on-year increase19.5%, higher than the same period of last year.9.1Percentage points, accounting for the total output value.32.2%. Investigation shows that enterprises from other provinces have completed their output value in Shaanxi.991.11100 million yuan, down from the same period last year.24%, down from the same period last year.34.4Percentage points.

As the Spring Festival approaches, the taste of the year is getting stronger all over the country, and the sales of new year goods are getting stronger.

CCTV News:With the approach of the Spring Festival, the flavor of the year is getting stronger all over the country, and the sales of traditional handicrafts such as lanterns and Spring Festival couplets and new year goods such as bacon are booming.

These days, the streets and alleys of Suining, Sichuan are covered with red lanterns, and there is a festive and lively atmosphere everywhere. Some urban landscapes with red, yellow and green as the main colors at intersections have also appeared one by one.

In the market, decorations such as red Spring Festival couplets, various blessings and Chinese knots are dazzling, and many window grilles, pillows and red envelopes with tiger characters and tiger patterns are also very popular. In addition to traditional holiday supplies, flowers have also become the choice of many citizens. Adding some auspicious flowers to the family not only brings a good mood for the new year, but also dresses up the festive atmosphere.

In Sinan, Guizhou, Tujia bacon such as sausage is popular in the market.

Due to the epidemic, many Sinan people who are away from home choose to celebrate the New Year on the spot, and buying local new year’s goods through the Internet has become their first choice to feel the taste of their hometown. Sinan Tujia preserved meat has a long history. It enters the twelfth lunar month every year, and the preserved meat is fragrant everywhere in Sinan urban and rural areas. People cut pork into strips and chunks when making preserved meat, and pickled it with more than 10 seasonings such as pepper, pepper and star anise for 5-mdash; After 7 days, it was baked with smoke and charcoal fire.

In Nanning, Guangxi, on the eve of the Spring Festival every year, festive New Year’s Eve flowers are an essential new year’s goods in many citizens’ shopping lists.

As the Spring Festival approaches, the sales of handicrafts symbolizing festive atmosphere in Gaoping, Shanxi are hot. In the manual lantern production workshop, workers step up the production of various lanterns, with a clear division of labor in painting, pasting and assembly. It takes at least one day to make an ordinary lantern. Handmade workers integrate modern aesthetics on the basis of traditional handicrafts, and social fire props such as dragon dance, lion dance, dry boat and Jiulian lantern create a strong auspicious and festive flavor.

Bright spots! "2022 Spring Festival Gala" is worth looking forward to.

  Happy new year, happy and auspicious. On the morning of January 27th, the Central Radio and Television General Station held a press conference on the Spring Festival Gala in 2022. The relevant person in charge introduced in detail a number of innovative highlights of this Spring Festival Evening.

  Hard core technology brings all-round audio-visual enjoyment

  In the innovative practice of building the strategic pattern of "5G+4K/8K+AI" in the Spring Festival Evening of 2022, a number of cutting-edge scientific and technological means were actively applied, making the Spring Festival Evening a big stage for the media scientific and technological innovation display of the Headquarters.

  △ Jiang Wenbo, a member of the editorial meeting of the Central Radio and Television General Station, introduced the highlights of technological innovation in the Spring Festival Evening of 2022.

  8K Ultra HD TV is the highest level TV standard in the world today. The main station is not only a participant in the formulation of this standard, but also a practitioner of its application. After a year’s efforts, the 8K ultra-high-definition TV standard of the main station has completed the construction of the full link system of 8K production, broadcasting, transmission and presentation. This year’s Spring Festival Gala will be broadcast live on CCTV-8K Ultra HD channel. At the same time, the city will be lit up through "100 cities and thousands of screens", and a brand-new spatial media communication matrix will be constructed by the integration of "8K ultra-high-definition channel+landmark big screen". It is worth mentioning that the audience can listen to the TV sound synchronized with the 8K ultra-high-definition big screen through the "100-screen Walkman" WeChat applet, so that people can enjoy the ultra-clear, colorful and vivid audio-visual feast in front of the outdoor big screen.

  This year’s Spring Festival Gala used LED screen for the first time to create a 720-degree dome space, and the giant dome design made the audience and the main stage integrated. The LED screen of 4306 square meters constitutes a highly malleable three-dimensional broadcast space, which breaks through the space limitation. For the first time, the sound reinforcement system is designed by multi-point sound reinforcement in different regions, and the volume and time delay of speakers in each region are accurately controlled, creating a good listening environment for the audience.

  In addition, there are 130 4K cameras in the studio hall. Through the real-time processing and production of the collected video stream, the wonderful free-view video content such as "time and space condensation" and "multi-dimensional transformation" can be watched continuously, which fully meets the audience’s personalized immersive viewing needs.

  The main station also makes full use of XR, AR virtual vision technology, holographic scanning technology and 8K naked-eye 3D presentation technology to break through the time and space constraints and bring vivid stereoscopic images to the audience. The AI multi-modal moving capture system is used to collect the actor’s trajectory and figure, and the three-dimensional coordinates of the actor’s figure image are calculated in real time by AI algorithm, so that the digital model and the actor can complete the action performance synchronously, efficiently and accurately, and create a magical visual effect of virtual and real interaction.

  The content is novel and unique, restoring the true nature of life

  The 2022 Spring Festival Gala adheres to the main tone of "happiness, auspiciousness and jubilation", adheres to the creative principle of "keeping integrity, innovating and creating new colors", pays attention to the organic combination and mutual transformation of ideas, art and technology, and strives to show the real and simple life with rich program styles, and highlights the annual flavor of reunion, reunion and unity in a festive and warm atmosphere.

  △ Wang Xiaozhen, member of the editorial meeting of the Central Radio and Television General Station and director of the editorial office, introduced the overall preparations for the Spring Festival Evening in 2022.

  The whole party not only has many kinds of programs familiar to the audience, such as language, song and dance, folk art, magic acrobatics, etc., but also has creative programs full of innovative atmosphere and high-tech means, creating a strong atmosphere of family reunion and happiness, and at the same time showing the world the festive colors of China’s land to bid farewell to the old and welcome the new, and Chinese people around the world to welcome the traditional festivals.

  Language programs immerse the heart, feelings and thoughts into daily life, and strive to show various life appearances through different observation angles. There are warm comedies that reflect the deep affection between father and son, the relationship between mother-in-law and daughter-in-law, stories that satirize dishonest behavior, and cross talk performances that imitate others … … Let everyone feel colorful life in knowing laughter.

  Song-and-dance programs will use a series of affectionate works to show the true feelings and the beautiful picture of the times, and carry forward and inherit the excellent Chinese traditional culture. Among them, there are not only carefully created new tracks, but also well-known classic melodies, showing China’s innovative changes, beauty of the times and forge ahead in the new era.

  △ 8K TV set displayed on site

  This year’s Spring Festival Evening also paid special attention to inviting many famous old artists such as Li Xuejian to be present, and gathered in the studio with a group of young and middle-aged powerful actors to join the people of the whole country in bidding farewell to the old year and welcoming the new year.

  Cross-screen gala

  The "Spring Festival Evening Broadcast Matrix" forms a "blowing open the petals of ten thousand pear trees" trend.

  The Spring Festival Gala has gone through forty years, which is the emotional sustenance and aesthetic enjoyment of the vast audience, and it is also a beautiful companion for family reunion. This year, the reception desk will launch "Watching the Spring Festival Evening with Vertical Screen" for the first time, providing a brand-new visual experience for the audience. The system will realize the mixed production and broadcasting of high-definition and 4K new media signals on the spot with lightweight and all-IP deployment, and the unified switching of horizontal and vertical screens, so as to realize the new mode of "cross-screen" live broadcast in the Spring Festival Evening of 2022. Users can independently choose fresh viewing angles through new media platforms such as CCTV video, CCTV news and CCTV literature and art, highlighting the youth and new vitality of the Spring Festival Evening.

  In addition, a series of wonderful programs, such as While the Spring Festival Gala is Going on, The Year of Dragon and Tiger Leaping in China, The Legendary China Festival, will form a "Spring Festival Gala Broadcasting Matrix", which will extend the joy, auspiciousness and jubilation of the Spring Festival Gala to the whole Spring Festival holiday and accompany the broad audience to have a happy reunion year.

  On New Year’s Eve, "Spring Festival Gala 2022" will be broadcast simultaneously on CCTV comprehensive channel, variety channel, Chinese international channel, national defense and military channel, children’s channel, agricultural and rural channel, Olympic channel, 4K/8K ultra-high-definition channel and other broadcasting frequencies, such as the sound of literature and art, the sound of music, classical music broadcasting, the sound of Greater Bay Area, the sound of the South China Sea, the sound of Taiwan and the sea, Chinese global broadcasting and China traffic broadcasting.

  At the same time, CCTV video, CCTV news new media, CCTV network, cloud listening and other new media platforms are broadcast simultaneously. CGTN (China International Television) English, Spanish, French, Arabic and Russian channels and 44 foreign new media platforms will link more than 600 media in more than 170 countries and regions around the world to broadcast and report the Spring Festival Gala live.

  Starting from the "new", give your heart and soul. The reception desk will use the next few days to polish every program carefully, and go all out to create a successful, wonderful and unforgettable Spring Festival Gala, and create a happy, festive and peaceful China Year with a well-cooked dinner. Let’s meet in the Spring Festival Evening and go to spring together!

How to balance the diet? Expert Interpretation of Reference Intake of Dietary Nutrients for China Residents (2023 Edition)

  On October 26th, an exclusive interview with DRIs was held in Beijing.

  Yang Yuexin, Chairman of China DRIs Revision Expert Committee and Chairman of China Nutrition Society, Ma Aiguo, Deputy Chairman of the Revision Committee and Executive Vice Chairman of China Nutrition Society, Ding Gangqiang, Deputy Chairman of the Revision Committee, Secretary of the Party Committee of China Nutrition Society and Director of the Institute of Nutrition and Health of China CDC, Yang Xiaoguang, Vice Chairman of China Nutrition Society and researcher of the Institute of Nutrition and Health of China Center for Disease Control and Prevention, Peng Xianwu, the supporting unit of DRIs revision and general manager of Amway (China) Science and Technology Innovation Center, attended the interview and interpreted the new revision.

Expert Interpretation of Reference Intake of Dietary Nutrients for China Residents (2023 Edition)

  Yang Yuexin introduced that the 2023 edition of China DRIs is the ninth edition. The revised expert committee and technical working group composed of nearly 100 nutrition experts lasted for three years. Based on the four basic principles of scientificity, advancement, integrity and continuity, the different reference intakes of 20 age groups including energy, nutrients and other dietary ingredients and pregnant women and lactating mothers totaled more than 70 nutrients and other dietary ingredients, which were revised and confirmed, and were held at the 14th Asian Nutrition Conference in September 2023.

  The revision of DRIs in 2023 mainly includes four aspects. First, the concepts and procedures have been improved and perfected. Different procedures for determining different reference values of nutrients have been newly formulated, and the technical points of each link of the formulation procedures have been uniformly determined. The concepts and connotations of recommended intake and specific recommended values for reducing the risk of diet-related non-communicable diseases have been further clarified and improved. Secondly, the basic reference values of China population were formulated and revised, including age grouping, representative weight, reference value of breast milk composition, recommended weight gain of pregnant women, PAL of physical activity level, etc. Thirdly, the new research results of nutrients and other dietary components in the past decade at home and abroad in the fields of function, evaluation, requirement, safety and prevention of chronic diseases have been included, and more research results targeting China residents have been included. Fourth, from the writing framework, format and other styles, it highlights the positioning of reference books centered on quantitative values.

Reference Intake of Dietary Nutrients for China Residents (2023 Edition) (DRIs)

  Peng Xianwu believes that this revision has far-reaching guiding significance for the big health industry, such as the data of newly added plant nutrients such as coenzyme Q10 and Lycium barbarum polysaccharide, and the quantification of nutrients such as proanthocyanidins, which will help Amway and industry to develop products and guide consumers to use them.

  Peng Xianwu introduced that in 2022, Amway and China Nutrition Society established Nutrilite Special Fund for Plant Functional Components and Health Research, aiming at attracting more research institutions and personnel to participate in the research direction of plant nutrients, opening up production, learning and research, transforming research results into products faster, and making more scientific research results benefit the public.

Peng Xianwu, General Manager of Technical Regulations of Amway (China) Science and Technology Innovation Center

  This revision has greatly changed the protein intake of the elderly and the calcium supplement standard for adults. Yang Xiaoguang believes that China has entered an aging society, and the elderly and ordinary people can’t meet the demand for protein, which is easy to lead to sarcopenia. Therefore, it is necessary to improve the dietary structure of the elderly and increase the intake of protein. Yang Xiaoguang introduced: "The 2023 edition of DRIs revised the requirement of protein for the elderly aged 65 and above in China, and its recommended intake increased from 0.98 g/(kg day) to 1.17 g/(kg day), which is an important achievement".

  Ding Gangqiang said that in recent years, the health awareness of Chinese residents has been continuously strengthened, and dietary nutrition and healthy behaviors have been continuously formed, but chronic diseases related to nutrition are still increasing. It is hoped that the release of the 2023 edition of DRIs will further guide the needs of China residents in all aspects of dietary nutrition, especially how to achieve a reasonable and balanced diet, and complete the objectives of the second largest action of Healthy China Action-Reasonable Diet Action.

  The revision of DRIs has a wide range of significance and value. First, it has scientific value, which determines the types and quantities of nutrients that each person should consume every day qualitatively and quantitatively. Second, social value is an important basic data support for formulating relevant policies, regulations and standards; The third is the value of technical support, which plays an important guiding role in the dietary design and evaluation of collective feeding units such as schools and nursing homes, the nutrition labeling of prepackaged foods, and the product research and development of food enterprises.

Global news: US stocks fell across the board, gold continued to refresh, and Tesla’s share price fell by nearly 30% during the year.

  On Tuesday (April 2), Eastern Time, the second quarter of the US stock market seemed to have a bad start. The three major indexes of the US stock market fell across the board overnight. They all fell more than 1% in intraday trading, and the Dow fell nearly 400 points to a two-week low, the biggest daily decline in four weeks with S&P. The expectation of interest rate cuts in the first half of the year was frustrated, and the yield of US bonds rose again, which suppressed the market to some extent. However, the performance of gold is still strong and continues to refresh.

  At the close, the S&P 500 index fell 0.72% to 5205.81 points; The Dow Jones index fell 1.00% to 39,170.24 points; The Nasdaq index fell 0.95% to 16,240.45.

  In terms of US bond yield, the 10-year US bond yield once rushed above 4.4% to close at 4.36%, and the 2-year US bond yield, which is most sensitive to the Fed’s policy interest rate, closed at 4.70%.

  Since Powell reiterated last week that he was in no hurry to cut interest rates, the market sentiment has not been high. And overnight, internal officials of the Federal Reserve once again consolidated this statement, and market sentiment was once again hit.

  San Francisco Fed President Daley said that three interest rate cuts this year are a baseline forecast and can be increased or decreased if necessary. The former "big hawk" and Cleveland Fed President Meister also expect to cut interest rates three times this year, and it is not excluded to cut interest rates in June, and the reasons for cutting interest rates in May are insufficient; Both warned of the risk of cutting interest rates prematurely.

  It is worth noting that the economic data of the United States even triggered speculation about whether the Fed will cut interest rates three times this year. The data released on Tuesday showed that the number of job vacancies in the United States has not changed much compared with the previous value, or it indicates that the labor demand is still stable at a high level in the high interest rate environment.

  LPL Financial analysts pointed out that although the Fed does expect to cut interest rates sometime this year, the argument that interest rates will be higher for a longer period of time is playing a role again, so this worries the market. He also explained from another angle why the market will pull back. A healthy market really needs to pull back. The current trend is not necessarily a bad thing. The S&P 500 index has still risen by about 9% so far this year. Therefore, the market outlook still needs to keep a close eye on the US economic data.

  On the enterprise side, Tesla released the latest car delivery data, which was not as good as the market expectation. The share price fell by 4.9% overnight, and it has fallen by nearly one-third during the year, and its market value has been erased by 260 billion US dollars. The data shows that Tesla’s delivery volume in the first quarter decreased by 8.5% year-on-year to about 386,800 vehicles, which was far lower than the analyst’s previous average expectation of 449,080 vehicles, which was the biggest worse than expected in history. During the same period, about 433,400 vehicles were produced, which was also lower than expected.

  This is also the first time that Tesla has fallen below the 400,000-vehicle mark since the third quarter of 2022, a decrease of over 8.5% compared with the delivery of 422,875 vehicles in the first quarter of last year, recording the first year-on-year decline since the second quarter of 2020.

  In the first quarter, Tesla faced a double blow of reduced demand for electric vehicles and high interest rates. Analysts had previously lowered their expectations for Tesla’s delivery. Some analysts pointed out that Tesla would experience the first year-on-year sales decline since the early days of the epidemic.

  In addition, Tesla also faced many obstacles in the first quarter, such as the interruption of the supply of spare parts in the Red Sea caused by the attack of Houthi militia and the temporary suspension of production in the German factory. Although the next generation model is the key to growth, the production of this model is not expected to start until late next year, which means that the company may face the risk of slowing down growth before this.

  [Hot stocks]

  Among the popular US stocks, Microsoft fell by 0.74%, Google A by 0.60%, NVIDIA by 1.01%, Amazon by 0.16%, Apple by 0.70%, Meta by 1.23%, AMD by 2.53%, Arm Holdings by 2.07% and Netflix by 0.02%.

  Due to the delivery of Q1 far less than expected, Tesla fell by 4.9%, and has fallen by nearly one-third during the year.

  Global stock index

  In the European stock market, the FTSE 100 index in Britain fell slightly by 0.22% to 7935 points. The French CAC40 index fell slightly by 0.92% to 8130 points. Germany’s DAX index fell 1.13% to 18,283 points.

  In Asian stock markets, the Hang Seng Index rose 2.36% to 16,932 points. The index of state-owned enterprises rose 2.58% to 5961 points. The Nikkei 225 index fell 0.73% to 39,625 points.

  [China Stock Market]

  Nasdaq China Jinlong Index closed up 0.32%. In terms of popular Chinese stocks, Pinduoduo fell by 0.77%, TSMC by 0.88%, Weilai by 2.16%, Xpeng Motors by 2.26%, Alibaba by 0.61%, Baidu by 0.08% and Netease by 1.88%.

  [foreign exchange commodities]

  The US dollar index rose first and then fell, once standing above the 105 mark in intraday trading, and once fell to an intraday low of 104.67 during the US session, then rebounded and finally closed down by 0.19% to 104.81.

  Gold futures for June delivery in the New York Mercantile Exchange closed up 1.09% at $2,281.80 an ounce, a record closing high, having risen to $2,297.70 an ounce in intraday trading. May silver futures closed up 3.39% at $25.923 an ounce.

  Geopolitical risks have enhanced the attractiveness of gold, while traders have avoided the shadow cast by the strong economic data of the United States on the prospect of the Fed raising interest rates.

  Oil prices continue to rise due to supply concerns. WTI crude oil rushed above $85 in intraday trading, rising more than 2% in the day, and continued to hit a new high since October last year, finally closing up 1.76% to $85.47/barrel; Brent crude oil also hit a new high since October last year, and finally closed up 2.12% to $89.27/barrel.

  [Highlights]

  The Fed reiterated that it is not in a hurry to cut interest rates, but it is still possible to start in June?

  San Francisco Fed President Daley said that three interest rate cuts this year are a baseline forecast and can be increased or decreased if necessary. Regardless of changing the inflation target, the continuous rise in oil prices will become a problem; The former "Great Hawk" and Cleveland Fed President Meister also expect to cut interest rates three times this year, and it is not excluded to cut interest rates in June, and the reasons for cutting interest rates in May are insufficient; Both warned of the risk of cutting interest rates prematurely.

  Job vacancies in the United States in February were slightly higher than expected

  The voluntary turnover rate is the lowest since 2020, and the number of layoffs is the highest in nearly a year. The number of JOLTS vacancies in the United States in February was 8.756 million, slightly better than expected, and the value was revised down to 8.748 million before January. The voluntary turnover rate in February was 2.2%, the lowest level since 2020. Due to the increase in layoffs in the leisure and hotel industries, the number of layoffs has risen to the highest level in the past year.

  Tesla’s quarterly delivery dropped for the first time in nearly four years, and its market value has evaporated by $260 billion in the year.

  On Tuesday, Tesla Corporation, an American electric vehicle manufacturer, released a report on automobile production and delivery in the first quarter of 2024. According to the specific data, Tesla delivered a total of 386,810 vehicles in the first three months of this year, far below the analyst’s previous average expectation of 449,080 vehicles, which was the biggest worse than expected. This is also the first time that the company has fallen below the 400,000-vehicle mark since the third quarter of 2022, which is over 8.5% lower than the delivery of 422,875 vehicles in the first quarter of last year, recording the first year-on-year decline since the second quarter of 2020.

  Intel’s report shows that the loss of its foundry business expanded in 2023.

  In a document submitted by Intel on Tuesday, Intel said that the sales of its new manufacturing division, Intel Foundry, in 2023 were $18.9 billion, down from $27.5 billion in the previous year, and the operating loss increased from $5.2 billion in 2022 to $7 billion. It is estimated that the loss will reach its peak in 2024 and will be realized at the operational level "in the middle of now to the end of 2030". Intel shares fell more than 2% after the report was released. Intel’s entry into outsourcing chip production is one of the biggest transformations in the company’s history. CEO Pat Gelsinge’s recovery plan also includes restoring the company’s once impeccable technological advantage, which the chip giant lost in the years before he took office in 2021.

  A major breakthrough in AI pharmaceutical! Stanford SyntheMol model develops new antibiotics

  According to a report by Stanford Medical College on March 28th, researchers from Stanford Medical College and McMaster University have made important progress in this field. They have developed an AI model called SyntheMol, which can synthesize drugs and create formulas for chemists in the laboratory.

  The model creatively designed six new drugs for drug-resistant bacterial strain Acinetobacter baumannii, which is one of the main pathogens causing antibiotic resistance-related deaths. The model not only created a new drug structure, but also provided a detailed formula for chemical synthesis, enabling chemists to synthesize these drugs in the laboratory.

  Abbott’s heart valve repair system has been approved by FDA to provide patients with new treatment options.

  On Tuesday, US medical and health company Abbott announced that its heart valve repair system has been approved by the US Food and Drug Administration (FDA), which is suitable for patients with potentially fatal heart disease. Abbott’s minimally invasive transcatheter TriClip repair system aims to treat tricuspid regurgitation (TR), which is a disease in which the valve between the right ventricle and the right atrium of the heart cannot be closed normally, resulting in blood reflux. Abbott has incorporated TriClip into its so-called "Fab 5" () equipment portfolio, which is expected to promote the company’s sales growth in the next few years, representing Abbott’s technological innovation and market leadership in their respective fields.

  [financial calendar]

Seven membership systems in the era of e-commerce

In the retail circle, the membership system has been iterative, so we might as well look at the membership logic from Amazon, Nike, Sephora, Starbucks and Xiaomi.

This article comes from WeChat WeChat official account:Retail Watch (ID: On Retail), author: Wang Ziwei

For retailers, the membership system is basically unavoidable. Let’s take a look at what the most mainstream membership system in the e-commerce era is like.

From a global perspective, there are seven most common forms:

1. Integral-hierarchy system

2. Service subscription system

3. Entity subscription system

4. Charity system

5. Sharing cooperation system

6. Community system

7. TOKEN system

I. Integral-Hierarchy System

This is almost the simplest one. In short, every time you spend X yuan, you get Y points. The more you spend, the higher the score.The only variable seems to be that there may be reward points at different times and through different channels, such as 5 times points for in-store consumption during the celebration period and 10 times points for e-commerce consumption during the Black Five/double 11 period.

Let’s take a foreign example, that is, the clothing brand "North"(North Face)",its integral system is called" VIPeak ".

For consumers, understanding this system is also very simple, that is, for every dollar spent, they get 10 points-whether online or offline, if they spend at outlets, they get 5 points for every dollar.

These points can be used in future consumption. To this end, North Face allows users to manage their accounts, buy goods, see points and redeem rewards through the App.

This is the simplest point system, through which consumers are willing to continue to shop. North Face is a typical single-level membership system.

Based on this logic, there will be a multi-level membership system, generally and periodically.(e.g. 1 year)The consumption amount or points are positively related.The characteristic of hierarchical system is that the higher consumers spend, the more rewards they get.

This level itself is also a gamification system, which links consumption with "playing". In the United States, a classic case is the beauty brand e.l.f

Consumers with 0-100 points are at the first level, consumers with 101-400 points are at the second level, and those with 401 points or above are at the highest level-the more membership points, the more unique the rewards.The uniqueness of the highest level is an important factor that urges consumers to buy more goods.

From the point of view of points, the first-level consumers get 2 points for spending 1 dollar, the second-level consumers get 4 points for spending 1 dollar, and the third-level consumers get 6 points for spending 1 dollar, and consumers can get corresponding services by using points.

Similarly, Starbucks in the United States also has this hierarchical system, which is divided into green card levels.(Green Level)And gold card level(Gold Level).

When the user has less than 299 stars, it is a green card level, and will enjoy the privileges of getting 2 stars for every $1 spent, birthday gifts, mobile payment, placing orders in advance, and free refills in the store; When the number of stars reaches 300 or above, the user will be upgraded to the gold card level. At this time, he will not only enjoy all the green card level permissions, but also double the star accumulation day every month, get a gold card membership card with his name printed on it, and exchange free food or coffee every 125 stars.

In addition to getting stars through consumption, there are also some activities in Starbucks APP, such as going to the store for consumption at a specific time, getting extra stars, and buying specific goods to get extra star rewards.

Second, the paid subscription system-service category

In the payment system, consumers need to pay a monthly fee or an annual fee to become a VIP. Generally speaking, there must be a solid consumer base.After all, it is difficult for you to make a new user become a paying member with little contact with you, so this payment system is basically used to maintain experienced users.

In addition, this payment system must have membership benefits, otherwise users don’t have to pay you in vain.

The most classic case is Amazon. Now Prime with an annual fee of $119 only needs $79 at the earliest, but only one problem was solved in that year, that is, it was guaranteed to be delivered free of charge within 2 days. This was the biggest problem of e-commerce in that year, otherwise a product would only be available in 2-3 weeks, and even if the price was superior, it could not wait.

Later, many functions were added to Prime for free, such as Amazon music, Amazon photos (unlimited storage of photos) and Amazon videos.(Watch all kinds of movies, dramas and original dramas at will)Wait a minute. In 2018, according to data from investment bank JP Morgan, the annual membership fee of $119 is worth about $784, which can be said to be over-valued.

The extreme, even extreme, is Costco.After covering the cost of goods, personnel and management expenses, the income generated by its goods is almost used up, so that its final profit returned to shareholders and membership fees are almost equal.

Third, the paid subscription system-commodity category

Another logic of the payment system is, "subscription box.(Subscription Box)Type ",that is, the subscription of physical items such as products/commodities.

The goods in the "subscription box" generally need to be purchased repeatedly. Take Bean Box as an example, it is the subscription of coffee-normal purchase is the normal price, but if you subscribe, you can always receive coffee on schedule within a cycle, and you can enjoy a discount.The essence is a behavior of directly locking consumers and locking demand, and then it may be the reverse supply chain.

Another advantage of this subscription is that it can increase the lifetime value of customers-from the case of Bean Box, can it be the same if you let consumers buy once and realize repeated service for six months, and let consumers buy for one month and one month?

Amazon has a similar service, and some products can be "subscribed" directly on the purchase page-usually with a discount of about 5%.

Fourth, the charity system

Discount can be a component of the membership system, but it is not necessary.

Therefore,The logic of the charity system is that you are attracting consumers with your own values, thus establishing a stronger relationship.The more common way is that enterprises donate a percentage of their income to charity, such as donating the money to charities, disease research institutions, animal protection organizations and so on.

A small evolutionary version here is that the enterprise will give you several optional donor institutions, and you can choose the one you are willing to donate. This is the case with The Body Shop in America, which introduced animal welfare into its membership system.

In addition to receiving rewards and VIP treatment, consumers can also choose to donate a percentage of their spending to Born Free USA, an animal welfare institution. This is also because The Body Shop has always emphasized environmental responsibility.

This logic lies in that the communication with consumers is not only the exchange of goods and services, but also the integration of values, which in turn makes the loyalty of consumers come to a different and uncontested field.It can be said to be a "blue ocean strategy of values".

V. Sharing cooperation system

A consumer will not only have a membership card, so the demand is also diverse. It can be said that consumers’ spending time is very idle, and the core is whether businesses from different formats can "cut leeks" together-buy electronic products from you, shoes from me and snacks from him.

Therefore, consumers will also want more flexibility in rewards. At this time, what is needed is cross-industry cooperation, which is equivalent to consumer sharing. After all, every enterprise has private domain traffic and data is single-segmented. If(Where permitted by law)Realize the docking of data, then almost draw the whole life of consumers.

In the United States, Nike’s membership system is like this. It has cooperated with Apple, Classpass and Headspace. These companies are not randomly selected, but can be linked to sports. They belong to the cooperation of several enterprises with sports as their core values.

At the same time, Nike also has a variety of apps for different sports to help members achieve their exercise goals. Then as long as the consumer’s behavior can be recorded by the App, then you can get a reward.

Japan’s Sakya Bookstore is also this logic, which focuses on life: through the T-card system, the parent company of Sakya Bookstore has opened 887,000 stores in 179 Japanese companies in May 2018, realizing the universality of points, and the profit does not come from the points themselves, but from the big data insight of consumers. Because consumer data is no longer just a single book purchase, eating, shopping, but all the synthesis.

In China, this kind of cross-industry cooperation is also gradually emerging. For example, JD.COM Plus can give you an iQiyi member.It is also the opening of data and traffic sharing between the two parties, which in turn turns traffic into "reservation".

VI. Community system

Beauty cosmetics brand Sephora(Sephora)Beauty Insider, a membership system, must be said. On the one hand, this system can be upgraded to three grades based on consumption, and every dollar spent in each grade can get different grades of points feedback.(1 dollar for 1 point, 1.25 points, 1.5 points respectively)At the same time, there are opportunities to get more exclusive services with the improvement of grades in the traditional "hierarchical system".

Besides,The biggest feature of Sephora’s membership system is the establishment of a community-to communicate with various members, find inspiration, participate in exclusive activities and so on.At this time, members of Sephora come to the brand community, and Sephora can understand the needs of consumers and then optimize its product design.

This logic also exists in China, that is, in Xiaomi’s community, a group of fans gather in the community to communicate with each other and put forward their own needs, and Xiaomi’s product manager can collect relevant information and update the corresponding system: users feel that they are valued, and Xiaomi has obtained consumer demand and met consumer demand, and both sides are happy.

Seven, TOKEN type

The last one is the TOKEN logic in the blockchain, or,Is similar to "asset securitization"(ABS)The idea of "assets token" should be called as a kind of "assets token"(ABT)”。

This kind of logic can be seen in China. At present, it can be simply divided into two types. The first type is "commodity tokenization", which is represented by the second-hand e-commerce enjoyment theory, and the second type is "behavior tokenization". I think the representatives are interesting headlines and today’s headlines. Let’s look at it together:

"Commodity Tokenization"

The problem with second-hand e-commerce is that the seller wants to sell an item that is "emotionally connected with himself", and based on game theory, the buyer will directly regard all second-hand goods as having a problem, forming a "lemon market effect" and paying a very low price, or, no matter how wonderful your price is and how perfect the goods are, I will ask for a 20% discount first and then post it-as long as I have sold something on idle fish once.

This will greatly reduce the efficiency of the transaction, and the seller will usually feel very uncomfortable, and finally there may be problems on the "supply side", which will have a negative effect on the market.

The logic of enjoying things is very interesting, that is, instead of introducing money, users use small red flowers. Users earn small red flowers through various behaviors, such as signing in and sharing, and then "exchange" other people’s goods with their own small red flowers. Because the little red flower is not anchored with the RMB, so,Users will participate in the purchase according to their real needs, rather than the "chopping behavior" caused by "consumerism".As a result, the pressure on both buyers and sellers is reduced, which greatly promotes the circulation efficiency of goods.

This logic actually exists in offline channels, that is, "moon cake tickets", that is, the moon cakes are placed there, and the person who finally gets the tickets goes to a specific place to pick up the goods. As for the intermediate process-the goods are not moving, and the tickets are flying around, which greatly reduces the cost. The logic of this set of freight tickets is "online" and combined with the mode of second-hand e-commerce, which forms the theory of enjoying things.

"Behavior Tokenization"

The second logic is "behavior token", which is the case with interesting headlines.

To put it simply, users can be rewarded for all their behaviors on the APP, including reading gold coins, watching videos, sharing gold coins, and rewarding users with "tokens" in a different way, and then this "token" is every cycle.(The period of interesting headlines is "1 day")Will be cleared, converted into RMB, accumulated to a certain amount, you can withdraw cash-or buy other goods directly in the APP.

The logic is simple,Retaining customers requires costs, so why not give these costs directly to customers as much as possible?And these sources of RMB are also simple, just divide the gross profit of each cycle directly. So now, we will find that many apps have this logic, such as the extreme version of today’s headlines, various headline apps, and various information apps.

Related links:"Integral Incentive System" from the Perspectives of JD.COM, Interesting Headlines and Amaya.

This article comes from WeChat WeChat official account:Retail Watch (ID: On Retail), author: Wang Ziwei

Rhododendron in Liangshan Scenic Area of Sichuan was killed by tourists: the whole branch was broken and the barbecue was lit.

  In May, the alpine rhododendrons in Liangshan Prefecture, Sichuan Province bloomed one after another, and the rhododendron sea all over the mountains attracted many tourists. This weekend, the Rhododendron Sea in Haikou Ranch, Puge County, Liangshan Prefecture became popular on the Internet, and was known as "the most beautiful Rhododendron Sea in Liangshan". However, in these two days, this flower sea was "poisoned" by tourists.

  On May 6th, Haikou Ranch was crowded with tourists who heard the news. According to incomplete statistics, more than 800 self-driving cars and more than 2,000 tourists entered that day. According to the local traffic police, the roads entering the pasture were lined up for several kilometers, and the traffic was once paralyzed. Before this weekend, the azaleas in Haikou Ranch were just a "secret place" known to a few people, not known to the outside world.

  On the morning of May 7, many Liangshan netizens forwarded another scene of Haikou Ranch in the circle of friends: after the tourists dispersed, a large amount of garbage was left on the ground, and the beer bottles they drank staggered. Sadly, some tourists break the branches at will and take photos in their hands.

  According to the photos provided by netizens, in a rhododendron viewing place, some people even dug up rhododendrons by roots and put them on pickup trucks to transport them away. Some netizens posted a photo taken in the Rhododendron Sea in Longjiaoshan, Huili County. After the whole flower was broken, it was ignited and burned to make barbecue wood.

  In Liangshan, azalea is called soma flower in Yi language, which is the welcome flower of Liangshan. "Soma is crying." Seeing these acts of destroying azaleas, many Liangshan netizens and tourists are very sad and have forwarded and condemned them in the circle of friends.

  The tourism department reminded that it is hoped that tourists can take care of the environment, take away garbage, don’t start with rhododendron, and protect the pure land of Haikou Ranch. At the same time, Rhododendron in Liangshan Mountain generally grows above 2800 meters above sea level. Below this altitude or the temperature is too high, it is difficult to survive, and it is useless to dig down the mountain.

  On May 7th, Puge County convened an emergency meeting of tourism, public security, forestry, environmental protection and other departments to deal with a series of problems caused by the recent sharp increase of tourists in Haikou Ranch. At present, Puge County Forest Public Security Bureau is also involved in the investigation.

Regarding the prevention of influenza, WHO’s latest recommendation of influenza vaccine strains in 2024-2025.

Foreword

Influenza virus can cause seasonal influenza, and may even cause a pandemic outbreak. Influenza virus is a negative-strand RNA virus with complex classification, numerous subtypes and easy mutation. At present, it is recognized that the best way to prevent influenza is vaccination. In order to ensure the effectiveness of the vaccine, the World Health Organization (WHO) updates the composition of the vaccine strain every year.

Changes of influenza vaccine strains in the northern hemisphere in 2024-2025

In order to keep the vaccine effective, it is necessary to update the components of influenza virus vaccine regularly. After analyzing the global influenza virus epidemiology, etiology and vaccine serology, WHO announced the recommendation of influenza vaccine components in the northern hemisphere from 2024 to 2025 on February 23, 2024.

?

Trivalent chicken embryo culture vaccine

an A/Victoria/4897/2022 (H1N1)pdm09-like virus

an A/Thailand/8/2022 (H3N2) -like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Trivalent cell culture or recombinant protein vaccine

an A/Wisconsin/67/2022 (H1N1)pdm09-like virus

an A/Massachusetts/18/2022 (H3N2)-like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Tetravalent chicken embryo and cell culture or recombinant protein vaccine

The following components are added on the basis of trivalent vaccine

a B/Phuket/3073/2013 (B/Yamagata lineage)-like virus

Since March 2020, the naturally occurring B/Yamagata virus has not been confirmed. WHO thinks that it is not necessary to use B/Yamagata virus as a component of influenza vaccine, and it should be removed from the component of influenza vaccine. Where tetravalent vaccine is still used, the composition of B/Yamagata line is consistent with the previous recommendation.

Comparing the composition of influenza vaccine in the northern hemisphere from 2023 to 2024, it was found that the change of composition was mainly due to the difference of H3N2 virus strains:

Vaccine types

2023-2024

2024-2025

Trivalent chicken embryo culture vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Thailand/8/2022 (H3N2) -like virus

Trivalent cell culture or recombinant protein vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Massachusetts/18/2022 (H3N2)-like virus

Recombinant antigen is the key material for vaccine research.

In influenza virus-related vaccines, drugs and even diagnostic reagents, key target antigens have played an important role. In the following table, we have sorted out the information of HA, NA and NP proteins.

albumen

function

app; application

HA

(hemagglutinin)

The sialic acid receptor on the host cell membrane binds to help the virus envelope fuse with the host cell membrane; Coagulation

Basic research on influenza

Influenza vaccine research and development

Development of anti-hemagglutinin antibody

Study on virus detection reagent

NA

(neuraminidase)

Hydrolyze sialic acid receptor to promote the release of mature virus particles

Research and development of antiviral drugs

Basic research on influenza

Influenza vaccine research and development

Antibody development

Study on virus detection reagent

NP

(nuclear protein)

Combine with influenza genetic material and participate in virus gene replication, transcription and translation; Maintain the stability of virus gene

Research and development of antiviral drugs

Basic research on influenza

Antibody development

Diagnostic product development

The recombinant antigen of influenza vaccine strain can be used in all aspects of vaccine development, such as vaccine content detection, vaccine biological titer detection and toxicological experimental research. Using recombinant antigen for ELISA detection, we can analyze the levels of serum total antibody and neutralizing antibody after vaccination, and use recombinant protein as control to detect the vaccine content.

The results of detecting the serum antibody level of mice immunized with vaccine by recombinant influenza HA protein (image from Andersen, et al.)

Influenza vaccine strain-related antigens are available in stock.

Yiqiao Shenzhou continues to pay attention to the research progress of influenza vaccine, and has built a relatively complete influenza virus research reagent library. It has been online to recombine some proteins of HA, NA and NP of the northern hemisphere influenza vaccine strain in 2024-2025, and it is available from stock. Order it now!

Consultation is polite!

After checking the information correctly, you can get a 35 yuan Luckin Coffee voucher.

Scanning code to understand the recombinant antigens related to components of influenza vaccine strains from 2024 to 2025;

references

[1]https://www.who.int/publications/m/item/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season

[2] Andersen, et al. Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief.[J]. Frontiers in Immunology.2021.747032.

[3] Bangaru S , et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface[J]. Cell, 2019.

[4] Kim M, et al. Inhibition of infection virus internalization by (-)-Epigallocatechin-3-gallate. [J]. Antiviral Research, 2013,100 (2): 460-472. Continue to slide to see the next one.

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