[Aika Auto Domestic New Car Original]

　　On September 17th, 2023, Geely Automobile officially announced the prices of two new models of the Star Yue L in Xi ‘an Black Light Factory, namely the Yun Qi version with a guide price of 157,700 yuan and the Skyline version with a guide price of 168,700 yuan. As new models, Yun Qi version and Skyline version have added exclusive design on the basis of Star Yue L, and are equipped with the latest vehicle system of Galaxy OS 2.0. While announcing the selling price, Geely Automobile also announced the car purchase courtesy including financial gift, rejuvenation gift, quality gift, maintenance gift and flow gift. At the same time, Geely Automobile also announced that it will push the Galaxy OS 2.0 car system for all old users OTA of Xingyue L for free.

　　The exclusive designs for these two models include the far-Dai matte gray car paint and the ink-splashing environment-friendly suede interior. Among them, the official guide price of Yuandai frosted gray car paint is 6,000 yuan, and the official guide price of splash-ink environment-friendly suede interior is 3,000 yuan, while the Sky Edition will come standard with splash-ink environment-friendly suede interior. The environment-friendly chamois interior is covered with a large area of environment-friendly chamois. The covering rate of the seat surface is 68.8%, the ceiling is 100%, and the door panel and instrument panel are all covered with chamois. Not only has the touch been improved, but the sense of advanced has also been filled. In addition, the Galaxy OS 2.0 car system has a brand-new UI design, which is more fashionable and beautiful. The voice wake-up speed reaches millisecond level, and the whole scene can be seen. At the same time, a custom desktop that is more in line with the operating habits of the mobile terminal is adopted to create a more intelligent and non-inductive interactive experience for users.

　　A quick look at the highlights of new cars

　　·　Newly added exclusive designs, including Yuan Dai matte gray car paint and splash-ink environment-friendly suede interior.

　　·　Equipped with the latest Galaxy OS 2.0 car system.

　　·　2.0T+8AT

　　New car introduction

　　In terms of appearance, Geely Xingyue L adopts the family-style design language of Geely Automobile 4.0 generation products, and continues to maintain the high value of atmospheric dynamics. In terms of details, the front face of Xingyue L adopts the iconic straight waterfall air intake grille, and the black middle net is decorated with chrome trim, which makes the front face look very delicate and dynamic. The headlight with full LED light source energy matrix is very sharp in shape, and the two-stage design is highly recognizable. A chrome-plated decorative strip is added to the front enclosure that runs through the design, which is perfectly integrated with the L-shaped chrome-plated decorative strips on both sides.

　　Viewed from the side, Xingyue L adopts a muscular line design, which, together with the burly body size, makes the side look very atmospheric. In terms of body size, the L length/width/height of Xingyue is 4770*1895*1689mm, and the wheelbase is 2845 mm.. The rear of the car continues the family’s atmospheric and steady design style. The biggest highlight is the adoption of the popular through taillights, and the interior adopts the "aurora dot matrix" design, which is full of scientific and technological sense.

　　As for the interior, Xingyue L has adopted a brand-new design concept of "Symphony of Time and Space", and all designs have demonstrated the people-oriented design idea. High-grade suede fabric is widely used in the interior, and the exquisite pearl stitching is used. With the special suede seat with the ultimate skin-friendly touch, the exquisite, elegant and unique car interior is created for the vehicle. In addition, three large 12.3-inch screens are also a highlight of the interior. The 12.3-inch central control screen uses Qualcomm Snapdragon 8155 chip, while the 12.3-inch screen in front of the driver integrates rich functions such as watching videos, listening to songs, games, Tik Tok and karaoke.

　　In the power part, the two new models are equipped with the high-power version of the Drive-E series 2.0TD engine, with a maximum power of 175kW(238 HP) and a peak torque of 350Nm. The transmission is equipped with the 8AT gearbox from Aisin.

　　Editor’s point of view: Up to today, the cumulative sales volume of China Star Series has exceeded 730,000 vehicles, among which the cumulative sales volume of Xingyue L has exceeded 300,000 vehicles, with an average monthly sales volume of over 10,000 vehicles. It is worth mentioning that in August, the sales volume was 17,169 vehicles, with the monthly sales exceeding 15,000 vehicles for three consecutive months. In the past five months, the sales volume of high-equipped 8AT products accounted for over 65%. The addition of the two new models not only brings a more exclusive design, but also brings a richer choice of models for consumers who are concerned about Xingyue L.

　　Wonderful content review:

　　The release of Geely Panda Knight is expected to be launched in early September.

　　Geely Panda mini "Asian Games Bear" has been listed for 29,900 times.

　　Geely Panda mini is officially listed at a price of 39,900 yuan.

1905 movie network news From, to, almost every summer, there will be a national ramble out of the tight encirclement. This year, the first film in the series of painting rivers and lakes — — The curse of the wind. After the trailer was released at Cannes Film Festival in 2014, five years later, The Wind Spell was finally produced and will be shown to the audience on July 13th. Let many fans sigh, and finally wait for you.

In the preview released this time, Xia Lan used the five elements of gold, wood, water, fire and earth to fight fiercely with fierce beasts. According to legend, only the power of wind can compete with it, revealing the meaning of the title "Wind Spell" and setting up a world view full of Chinese style. In the poster released together, the young volley confronted the huge gluttony, revealing a stirring story of the rise of a young hero.

　

The most valuable guoman IP　The Wind Spell permeates the national wind into every detail.

From its first broadcast in 2012 to the present, the painting rivers and lakes have created many high-quality comic dramas, such as Xia Lan, Bad Man, Soul Master, Cup Don’t Stop, and Changed Students, which can be said to be the most cosmopolitan and vital national comic, and also regarded as the most valuable national comic IP in the industry. Therefore, the first movie of painting rivers and lakes was placed high hopes by anime fans to help the rise of the country.

In the preview, the mythical gluttony in this world, Xia Lan uses the power of five elements to compete, and the teenager wants to be a hero when he enters the rivers and lakes … … The setting of the whole world outlook in the Wind Mantra is full of Chinese style. The same is true of the details. Fierce beasts, which are mostly composed of curved designs, and rivers and lakes in noisy streets are trying their best to convey an oriental aesthetics, which conforms to the audience’s imagination of "national ramble". Director Liu Kuo almost "digs" these details to the extreme. "Let the China audience like it first and see it comfortably."

　

Hold back the movie dream for six years and develop the only domestic animation engine.　"grab back" some audiences for Guoman

The completion of the Wind Spell took five years of preparation and three years of production. But the time behind it is far more than that. In the mind of director Liu Kuo, this movie dream has been held back for too long. "Although I had a dream of making movies long ago, I still held back. I want to make myself strong first. Because the country in my heart is made by ourselves. "

With this in mind, director Liu Kuo and the team started to develop a "Datura Engine" for animation. After six years of "darkness before dawn", China’s 3D animation finally has the original ability of the whole process. After tens of thousands of minutes of animation polishing, "Wind Spell" was finally launched. The film is about to be released, and Liu Kuo revealed his hope that "in the case that the China market has been occupied by Hollywood and Japanese animation for a long time, we can win back some audiences for domestic animated films in China"!

　　On May 17, Fu Linghui, spokesperson of the National Bureau of Statistics, said in response to the latest population data that China is currently in a state of mild aging.

　　Fu Linghui said that there are some misunderstandings in the society, and many people think that China has entered a deeply aging society. In fact, there is a general understanding in the world that a country’s population over 60 years old accounts for more than 10% of the total population, and this country has entered an aging society. Between 10% and 20%, it is mildly aging, between 20% and 30%, it is moderately aging, and over 30% is severely aging. According to the census, the proportion of elderly people over 60 years old in China is 18.7%, which shows that China is still in a state of mild aging. (CCTV reporter Yang Yi Zhou Ling)

　　Beijing, March 1 ST "The 19th National Congress of the Communist Party of China proposed to build an educational power, which is an arduous, historic and grand task. To build an educational power, we must first improve the quality of basic education, and we must first improve the quality of Chinese and mathematics." Recently, Wang Wenzhan, former director of the Department of Basic Education of the Ministry of Education and deputy chief inspector, said this at the launching ceremony of the national "Shui Mu Hsinchu Yingchun Cup" national youth mathematics comprehensive ability exhibition sponsored by the Central Network Film and Television Center of the Communist Youth League, undertaken by Future Network and Shui Mu Hsinchu Education, and supported by the Education Research Center of China Teacher magazine.

　　Launching Ceremony of "Shui Mu Hsinchu Yingchun Cup" National Youth Mathematical Comprehensive Ability Exhibition.

　　Wang Wenzhan, former director of the Department of Basic Education of the Ministry of Education and deputy inspector general, stressed that the activities should adhere to the "three natures" and "three noes", which are not only public welfare, exhibition and interesting, but also do not exceed the standard, increase the burden on students and rank second. It is also pointed out that basic education is the foundation of the whole education, Chinese and mathematics are the foundation of the foundation, and the education for teenagers in the whole country is the most important part of the education system, while the basic education for teenagers is the foundation of all education. Our country’s achievements in mathematics are excellent in the world, and it ranks among the top in the world. This excellent momentum will continue, and it needs the joint efforts of people from all walks of life who are enthusiastic about education.

　　Wang Wenzhan, former Director of the Department of Basic Education of the Ministry of Education and Deputy Chief Inspector.

　 　

　　Xin Tianhao, executive editor-in-chief of the Communist Youth League Central Network Film and Television Center and Future Network.

　　"Mathematical culture, as a spiritual and non-cognitive psychological level, is eternal, which can influence and achieve people’s life." Xin Tianhao, executive editor-in-chief of the Network Film and Television Center of the Central Committee of the Communist Youth League and Future Network, introduced it at the launching ceremony.

　　Lin Yuanlie, Professor of Mathematics Department of Tsinghua University

　　Lin Yuanlie, a professor of mathematics at Tsinghua University, and the leaders and guests present deeply discussed the charm of mathematics. He explained in detail two famous sayings of predecessors: "Mathematics is the key to open the door to science" and "Mathematics is the queen of science", and called on the vast number of young people in China to explore the endless treasure in mathematics.

　　Tian Yumin, Director of Education Research Center of China Teacher Magazine.

　　Tian Yumin, director of the Education Research Center of China Teachers magazine, also said that this kind of comprehensive ability exhibition has a positive role in promoting students’ learning ability and learning habits, and should be strongly supported by all sectors of society. The "Shui Mu Hsinchu Yingchun Cup" national youth comprehensive mathematical ability exhibition is a good start, and he is looking forward to more positive public welfare comprehensive ability exhibition activities.

　　

　　Wang Zhengpu, General Manager of Beijing Shui Mu Hsinchu Education Technology Co., Ltd.

　　"The purpose of this exhibition is to promote the mathematics culture, set off an upsurge of loving, learning and using mathematics in the whole country, and make students understand, like and enjoy mathematics more comprehensively, so as to continuously improve their mathematics literacy." Wang Zhengpu, general manager of Beijing Shui Mu Hsinchu Education Technology Co., Ltd., also said in his speech that students will appreciate the beauty of mathematics, build a spiritual communication between me and mathematics, and realize that mathematics plays an inestimable role in the development of human culture.

　　It is understood that the purpose of the "Shui Mu Hsinchu Yingchun Cup" National Youth Mathematical Comprehensive Ability Exhibition is to promote mathematical culture, stimulate the interest of primary and secondary school students in learning mathematics, explore more outstanding mathematics talents, develop their intelligence, popularize mathematical science, help the majority of young people discover their own mathematical talents, and enable students to fully understand, like and enjoy mathematics, and constantly improve their mathematical literacy. The proposition of this activity is universal and interesting, and all the topics seem simple, but students need to think hard in the process of solving them, and there are many solutions, which are helpful for students to open up their minds and stimulate the potential of mathematical comprehensive ability. Some topics combined with real-time hot spots make mathematics, an abstruse subject, return to life, and encourage students to apply what they have learned to solve practical problems in life with mathematical thinking.

　　From now on, the "Shui Mu Hsinchu Yingchun Cup" national youth mathematics comprehensive ability demonstration activity will be carried out one after another throughout the country, and the majority of young people who love mathematics can sign up for the activity.

Yu Xueyuan reminds

A new batch of influenza vaccine

Appointment vaccination has been opened.

Hurry up before the flu peak comes.

Arrange it for the children!

(Bao, it’s time for an injection)

Recently, a new batch (2023~2024 batches) of influenza vaccine has arrived in various places one after another, and it can be vaccinated by appointment.

On September 5th, China CDC suggested in the latest Technical Guide for Influenza Vaccination in China (2023-2024):

All people who are over 6 months old and have no contraindications should be vaccinated against influenza.

The CDC believes that

"This winter and next spring, you may face the risk of interaction or co-epidemic of respiratory infectious diseases such as COVID-19 and influenza."

In this situation, it is obviously necessary to vaccinate against influenza.

Is it too early to get a flu shot? How old can the child be vaccinated? How to choose several types of vaccines? ……There are still many concerns about the flu vaccine.

The following small series has compiled 9 frequently asked questions. Parents who are concerned about influenza vaccine should not miss today’s content ~

(Note: The new vaccination guide involves some updates and adjustments, and the following contents will also be popularized according to the new guide, so you may find that some information is different from what you have learned before, so it is recommended to take the new guide as the reference standard ~)

01

The flu vaccine is in place

Call now, is it early?

Say the answer first, not early, and just right.

Research data show that the epidemic season of influenza in winter and spring in China is usually from the middle and late October to the middle and early March of the following year.

After vaccination, the immune effect will not reach its peak until one month later.

According to the new guidelines: "The antibody protection level can be maintained for at least 6 months after influenza vaccination."

Vaccination now can just cover the upcoming peak of influenza in autumn and winter and the flu season in early spring next year.

When the flu peak comes, the antibody is just at the peak level, which can play a better protective effect.

02

The most important thing to vaccinate.

Who are they?

The new guidelines give priority to the timely vaccination of key and high-risk groups, including:

· Medical personnel, including clinical rescue personnel, public health personnel, health quarantine personnel, etc.;

·Older people aged 60 and over;

· People suffering from one or more chronic diseases;

· Vulnerable people and employees in old-age care institutions, long-term care institutions, welfare homes and other crowd gathering places;

· Pregnant women;

·Children aged 6-59 months (about 5 years old);

· Family members and caregivers of infants under 6 months old;

· People in key places such as kindergartens, primary and secondary schools, and supervision places.

Influenza vaccines are self-funded vaccines, but some areas have some free policies. Take Beijing as an example:

People over the age of 60, students in primary and secondary schools and emergency support personnel for major events can be vaccinated free of charge.

You can pay attention to the vaccination policy in your area.

03

What are the types of influenza vaccine?

How many shots? How to fight?

At present, there are trivalent inactivated influenza vaccine (IIV3), tetravalent inactivated influenza vaccine (IIV4) and trivalent live attenuated vaccine (LAIV3) approved for marketing in China, which are produced and supplied by different manufacturers.

In order to facilitate understanding, you can look at this table for specific vaccine types and applicable populations:

(Adults and children can refer to this table.)

Babies under the age of 6 months are also indirectly protected through the vaccination of their mothers during pregnancy and the vaccination of their caregivers and family members against influenza.

In order to gain sustained immunity,It is recommended that children be vaccinated against influenza once a year.Because the influenza virus is easy to mutate, the composition of the vaccine will be adjusted every year according to the prevalent strains of the year.

04

3 or 4, which is better?

Trivalent influenza vaccine can prevent influenza caused by influenza A (H1N1), H3N2 and Victoria B virus, while tetravalent influenza vaccine can alsoPrevent one more Yamagata virus B.

Source: Network

Although the virus coverage of tetravalent vaccine is wider than that of trivalent vaccine, the transmission ability and antigenic pathogenicity of influenza B virus are not as strong as that of influenza A virus.Therefore, vaccination with trivalent influenza vaccine can also prevent influenza virus.

There is no need for everyone to miss the best vaccination time in order to wait for the fourth price. After all,It is the most important thing to get vaccinated and protected in time!

05

Injection or nasal spray, which is better?

Whether it is injection or nasal spray, there is not much difference in safety and effectiveness.

You should notice that the injected vaccine is "inactivated" and the nasal spray is "attenuated". The difference lies in:

● Injection of influenza vaccine is to inactivate the virus, so that the virus loses its pathogenic ability but retains its antigenicity.

● Nasal spray vaccine is to culture and purify the live influenza virus, so that its virulence is weakened, but it can stimulate the human body to produce antibodies without pathogenic ability.

For babies who are very afraid of injections or dizzy needles, the nasal spray inoculation method is more moderate. But there is no need to pursue it deliberately. Again, timely vaccination is the most important thing.

06

The child has got the flu

Do you still need vaccination?

Need.

If the child accidentally gets the flu and has not been vaccinated against it before, he still needs to be vaccinated again after the baby gets better.

Because of influenza A,There is no cross-protection between different types.For example, if you have had H1N1 before, you will still get sick if you are infected with H3N2 next time.

07

Influenza vaccine can be combined with other vaccines

At the same time?

There are two situations.

Inactivated influenza vaccine (injection):Can be inoculated in different parts at the same time with other inactivated or attenuated influenza vaccines.

Attenuated vaccine (nasal spray):Can not be vaccinated with another attenuated vaccine at the same time, at least 4 weeks between them.

Can it be vaccinated at the same time as COVID-19 vaccine?

Over the age of 18, you can get inactivated influenza vaccine and COVID-19 vaccine at the same time;

Under the age of 18, it is recommended that the vaccination interval be greater than 14 days.

08

Taboos for influenza vaccination

Can egg allergy be vaccinated after all?

Egg allergy can be vaccinated against influenza.

People’s Republic of China (PRC) Pharmacopoeia (2010 edition, 2015 edition and 2020 edition) does not take people who are allergic to eggs as a taboo for vaccination.

The real vaccination taboos are the following!

You can’t get any flu vaccine.

(1) Those who are allergic to any ingredients contained in the vaccine (including auxiliary materials, formaldehyde, cracking agents and antibiotics) or have a history of severe allergic reaction to any kind of influenza vaccination.

(2) Patients suffering from acute diseases, severe chronic diseases or acute attacks of chronic diseases and fever are advised to be vaccinated after recovery or stable control.

(3) Guillain-Barre syndrome occurred within 6 weeks after previous influenza vaccination, which needs to be evaluated by a doctor.

Can’t be vaccinated with nasal spray attenuated influenza vaccine.

(1) Persons with low immune function due to drug use, HIV infection and other reasons.

(2) Children and adolescents treated with drugs containing aspirin or salicylic acid for a long time.

(3) Children with asthma aged 2-4 years.

(4) Have a history of Guillain-Barre syndrome.

(5) antiviral drugs such as oseltamivir and zanamivir were used 48 hours before inoculation, or palamivir was used 5 days before inoculation, or balosha was used 17 days before inoculation.

(6) In case of severe nasal congestion, it is suggested to suspend the inoculation of attenuated vaccine by nasal spray.

(7) Children with cochlear implants should avoid using nasal spray attenuated vaccine one week before and two weeks after operation.

(8) Pregnant women

There are still many contraindications for nasal spray attenuated vaccine.ofBefore choosing to vaccinate your child, you must pay attention to the above situation.

09

After vaccination

Will you still get the flu?

Maybe.

No vaccine can prevent the disease 100%, but vaccination can reduce the risk of infection andGreatly reduce the risk of serious illness and death.

According to the research data mentioned in the new guide, when influenza and COVID-19 are co-epidemic, after vaccination,At least it can achieve more than 70% protection effect.

Therefore, if no contraindications are involved, it is recommended to vaccinate in time, especially for the elderly and children.

Even if you are vaccinated against influenza, everyone should pay attention to prevention and maintain good hygiene habits.

Wash your hands frequently, ventilate frequently, go to crowded places less, wear masks when going to crowded places, and cover your nose and mouth when sneezing.

If you don’t know where to get a vaccine, you can refer to the following ways:

(1) Gaode or 114 inquires the telephone number of local hospitals, communities and epidemic prevention stations, and makes a phone call to consult about seedlings;

(2) Pay attention to WeChat official account, a local hospital, community and epidemic prevention station, and check whether there is an entrance for online seedling appointment;

（3）微信内搜索【疫苗服务预约】，选择所在城市，根据分类预约。

另外，育学园旗下北京弘和妇产医院也可约苗，在北京的朋友想了解可以拨打电话咨询??

咨询电话：(010)6549 1911

对流感疫苗还有其他问题，可以评论留言，小编会积极给大家解答~

最后，记得戳戳【在看】，和小编一起提醒大家，该！打！疫！苗！啦！

参考资料:

[1]中国疾病预防控制中心《中国流感疫苗预防接种技术指南（2023-2024）》

[2]上海疾控《流感疫苗可以安排了，给身体留出足够时间做准备》

[3]北京日报

免责声明：本文内容更新于2023年。文章仅提供一般的医疗、健康、用药、养育等方面的科普信息，不能代替任何个人的医学诊断和治疗。个人的医疗、用药问题请咨询医生。

授权转载：原创内容，欢迎转发，转载请留言。

01

这个孩子抹上脸的东西，可能导致性早熟！家里有的赶紧扔！

02

挨骂也要说，这种油别再吃了，家里有的赶紧扔！

03

扩散！这种家电每天都在释放「大量致癌物」！赶快提醒家里人

阅读原文」，下载育学园APP

Albinism is a kind of hereditary leukoplakia caused by melanin deficiency or synthesis disorder of skin and accessory organs due to tyrosinase deficiency or functional decline.

According to clinical manifestations, albinism can be divided into three categories: ocular albinism (OA), ocular skin albinism (OCA) and albinism-related syndrome, among which ocular skin albinism (OCA) is the most common and albinism-related syndrome is the rarest.

This paper mainly expounds the clinical manifestations, genetic causes and genetic counseling of OA and OCA.

Clinical manifestations of OA and OCA

Only the eye pigment in OA patients is reduced or lacking, while the eye, skin and hair in OCA patients are obviously reduced or lacking.

1, eye performance

① Iris transillumination defect (TID)-91% ~ 100% albino patients have TID.

② nystagmus

③ Fundus hypopigmentation —— It is caused by the decrease of retinal pigment epithelium and/or choroidal pigmentation, which often leads to obvious choroidal vessels in the posterior pole. It is reported that more than 94% patients with albinism have fundus hypopigmentation.

④ hypoplasia of fovea-characterized by the continuation of the inner layer of retina behind fovea and the decrease of cone photoreceptor specialization.

⑤ optic nerve abnormality

⑥ ametropia

2. Skin manifestations

The skin and hair color of albino patients may change with age.

① Skin and hair pigmentation score

Skin and hair pigmentation scores help to objectively determine the influence of hypopigmentation.

② Skin diseases

Including all albinos, regardless of skin color, the risk of ultraviolet (UV) light-related skin diseases will increase. The most important of these is skin cancer, which includes squamous cell carcinoma, basal cell carcinoma, melanoma and less common Merkel cell carcinoma.

Genetic causes of OA and OCA

The following table summarizes the genes known to be related to nonsyndromic OCA and OA. All nonsyndromic OCA are inherited by autosomal recessive mode. OA (always non-syndrome) is inherited in an x-linked manner.

The following table summarizes the genes known to be related to OCA syndrome:

Genetic counseling

1. Inheritance mode

Nonsyndromic ocular skin albinism (OCA) caused by pathogenic variation in TYR, OCA2, SLC45A2, SLC24A5, LRMDA (C10orf11) or DCT (TYRP1) is inherited in autosomal recessive way.

Ocular albinism (OA) caused by pathogenic variation in GPR143(OA1) is inherited by X linkage.

If an individual suffers from a specific syndrome related to OCA (such as Hermansky-Pudlak syndrome or Chediak-Higashi syndrome), genetic counseling is needed for this disease.

2. Autosomal recessive inheritance-risk to family members

Parents of the proband:

The parents of the affected children are presumed to be heterozygotes causing the pathogenic variation of OCA.

If molecular diagnosis has been established in the proband, it is suggested that the parents of the proband should be tested for molecular genes to confirm that both parents are heterozygotes causing the pathogenic variation of OCA and allow reliable recurrence risk assessment.

If the pathogenic variation is detected only in one parent, and the parental identity test has confirmed biological motherhood and parent-child relationship, one of the pathogenic variations identified in the proband may occur as a newborn event in the proband or as a zygote in the mosaic parent. If the proband seems to have homozygous pathogenic variation (that is, the same two pathogenic variations), other possibilities to be considered include:

The deletion of single exon or multiple exons in the proband was not detected by sequence analysis, which led to artificial homozygosity;

Parental chromosomes and single parent homomorphism of pathogenic variation lead to homozygosity of pathogenic variation among proband.

Heterozygotes (carriers) are asymptomatic and have no risk of developing the disease.

Siblings of the proband:

If it is known that both parents are heterozygotes of pathogenic variants that cause OCA, each sibling of the affected individual has a 25% chance of being affected at conception, a 50% chance of becoming asymptomatic carriers, and a 25% chance of inheriting any familial pathogenic variants.

Heterozygotes (carriers) are asymptomatic and have no risk of developing the disease.

Descendants of the proband:

The offspring of autosomal recessive OCA individuals are obligate heterozygotes (carriers) that cause the pathogenic variation of OCA.

Other family members:

Every brother and sister of the proband’s parents has a 50% risk of becoming the carrier of OCA’s pathogenic variation.

Carrier detection:

It is necessary to identify the pathogenic variation that causes OCA in the family in advance for carrier detection of at-risk relatives.

3. X-linked inheritance-risk to family members

Parents of male proband:

The father of the affected man will not suffer from this disease, nor will he be a hemizygote of the pathogenic variant GPR143; Therefore, he does not need further evaluation/testing.

In a family with more than one affected individual, the mother of the affected male is an obligate heterozygote. Note: If a woman has more than one affected child and no other affected relatives, and if family pathogenic variation cannot be detected in her white blood cell DNA, she is likely to have germline chimera.

If the male is the only affected family member (i.e., a simple case), the mother may be heterozygote, the affected male may have new pathogenic variation (in this case, the mother is not heterozygote), or the mother may have somatic/germline chimera.

It is suggested that the mother should be tested for molecular genes to confirm her genetic status and make a reliable recurrence risk assessment.

Brothers and sisters of male proband:

The risk of siblings depends on the mother’s genetic status:

If the proband’s mother has the pathogenic variation of GPR143, the chance of transmission in each pregnancy is 50%.

Men with genetic disease variation will be affected;

The female with genetic pathogenic variation will be heterozygote (i.e. carrier). Heterozygotes are usually unaffected, although they can show iris penetration defects, "mud splash" fundus appearance and fovea hypoplasia.

If the proband represents a simplex case and the pathogenic variation cannot be detected in the mother’s leukocyte DNA, it is assumed that the risk of sibs is low, but the risk is higher than that of the general population because of the possibility of maternal lineage mosaic.

Descendants of male proband:

The affected men spread the disease-causing mutation of GPR143 to all their daughters, but not to their sons.

Other family members:

Menstruation and maternal cousins of the male proband may be at risk of GPR143.

Note: Molecular genetic testing may be able to identify family members with new pathogenic mutations, and this information can help determine the genetic risk status of large families.

Heterozygote detection:

To identify female heterozygotes, it is necessary to identify the pathogenic variation of GPR143 in the family in advance.

Note: As carriers of this X-linked disease, women are heterozygotes, which are usually not affected, but they may show iris penetration defects, "mud splash" fundus appearance and fovea hypoplasia.

Source | Metz Medical official website

Write | ｜Anna.An

Original title: Inheritance and Manifestation of Albinism

Read the original text

Investment & Pensions Europe(IPE), an internationally renowned financial media organization, officially released the list of "Top 500 Asset Managers 2023".

The top 10 institutions in global asset management are BlackRock, Pioneer Pilot, Fidelity, State Street Global, Morgan Asset Management, Goldman Sachs Asset Management, Capital Group, Credit Suisse Oriental, Pinhao and new york Mellon Asset Management. There are 41 asset management institutions in China on the list, with excellent overall performance and greatly improved scale and ranking.

"Top 500 Global Asset Management Institutions List" is one of the annual reports of IPE. Headquartered in London, England, IPE is a well-known European financial media organization affiliated to IPE International Publishers Media Group, and enjoys a high reputation among global institutional investors and pension operators. IPE publishes authoritative lists such as the top 500 global asset management companies through market open data every year, and launches trend development reports, which has become an important vane in the global asset management field.

Top 20 of Global Asset Management 500 in 2023

Rank the total management scale of the headquarters of the asset management company at the end of 2022.

1. BlackRock US$ 8,052.9 billion.

2. Vanguard Investment Management US$ 6,743.3 billion.

3. Fidelity Investments US$ 3,653.6 billion.

4. State Street Global Advisors US$ 3,262.1 billion.

5. J.P.Morgan Asset Management US$ 2,616.4 billion.

6. Goldman Sachs Asset Management International US$ 2,152.1 billion.

7. Capital Group (US$ 2,044.3 billion)

8. Amundi France’s $1,904 billion.

9. PIMCO US/Germany USD 1,631.1 billion.

10. new york Mellon Asset Management US$ 1,615 billion.

11. Legal & General Investment Management UK $1,351.1 billion.

12. Jing Shun US/UK $1,320.7 billion.

13. Franklin Templeton US$ 1,296.4 billion.

14. Prudential Investment Management (PGIM) US$ 1,290.6 billion

15. Morgan Stanley Investment Management US$ 1,222.4 billion.

16. T. Rowe Price US$ 1,194.4 billion.

17. Wellington Management International US$ 1,082.4 billion.

18. Natixis Investment Management of France: US$ 1,078.8 billion.

19. Nuveen US$ 1,018.2 billion.

20. UBS Asset Management (UBS Asset Management) Switzerland 996.7 billion US dollars.

41 listed asset management companies in China

Rank company name

31. China Life Asset Management Co., Ltd.

36. Ping An Asset Management Co., Ltd.

64. Taikang Asset Management Co., Ltd.

E Fund Management Co., Ltd.

71. CMB Finance Co., Ltd. 85. Xingyin Finance Co., Ltd.

91. Jianxin Wealth Management Co., Ltd.

97. southern fund Management Company Limited.

99. Huaxia Fund Management Co., Ltd.

100. Agricultural Bank of China Finance Co., Ltd.

102. ICBC Wealth Management Co., Ltd.

103. BOC Wealth Management Co., Ltd.

ICBC Credit Suisse Fund Management Co., Ltd.

106. harvest fund Management Co., Ltd.

110. Guangfa Fund Management Co., Ltd.

112. Boss Fund Management Co., Ltd.

113. Xinyin Wealth Management Co., Ltd.

119. Pacific Asset Management Co., Ltd.

120. Xinhua Asset Management Co., Ltd

China Merchants Fund Management Co., Ltd.

122. China PICC Asset Management Co., Ltd.

124. Jianxin Fund Management Co., Ltd.

126. CITIC Securities Co., Ltd.

131. Fuguo Fund Management Co., Ltd.

142. Taiping Asset Management Co., Ltd.

145. Everbright Financial Management Co., Ltd.

151. Tianhong Fund Management Co., Ltd

153. Huitianfu Fund Management Co., Ltd

154. Penghua Fund Management Co., Ltd.

155, Yangtze River Pension Insurance Co., Ltd.

158. Bank of Communications Wealth Management Co., Ltd.

166. Everyone Asset Management Co., Ltd.

186, Yin Hua Fund Management Co., Ltd.

190, Ping An Finance Co., Ltd.

191. Minsheng Financial Management Co., Ltd.

194. Puyin Wealth Management Co., Ltd.

197. China Post Finance Co., Ltd.

200. cathay pacific fund Management Co., Ltd.

202. Sunshine Asset Management Co., Ltd.

208. Huatai Asset Management Co., Ltd.

210. China International Capital Corporation Limited

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Original title: "The list of the top 500 global asset management institutions in 2023 was announced, and 41 Chinese state-owned assets management institutions were on the list | List 1"

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Lord Yue Zun has taken on a new job.

Recently, a new drama in Dylan was launched. This drama is the costume drama "Floating Figure" starring him and Yukee Chen’.

Because of the popularity of Dylan, I heard that the number of reservations for this drama exceeded one million before it started.

To say how hot Dylan is, since the launch of "Freesia Tactics" a while ago, Yue Zun’s adult has been out of the circle almost every day, and 800 hot searches directly build a nest and settle down on the hot search every day.

In addition, these two days, the new drama began to broadcast, and the hot topics were one after another. There was a kind of entertainment that seemed to have no one but him.

01 New Drama Controversy

Speaking of the new drama "Floating Picture", this is his first work since the popularity of "Freesia", so it has attracted everyone’s attention.

However, after the play was broadcast, the comments were polarized. Some netizens think that the plot of this drama is novel and it is a cool drama without delay. However, some viewers think that Dylan’s makeup and hair styling is still ugly, and her acting skills are a little off-line. The acting skills of the hostess are even more complicated, and the audience’s comments are mixed.

Some people have given the play a five-star praise, and feel that the setting is novel and has a sense of humor, which will give people the desire to watch it.

In view of the appearance of the male host and the acting skills of the female host, many people directly made a one-star bad review, and their words were sharp.

Judging from the broadcast episodes, the hostess is clever, happy and cute, but the netizens’ comments on Yukee Chen”s acting skills are almost meaningless. A pair of beautiful and moving eyes are not the case when put into the performance. Because of the eye play, Yukee Chen’ was also crowned as "Wood Beauty" before.

Just look at this photo, please analyze the psychological activities of the characters.

Option 1: A group performance in front of the hostess made an incredible and amazing move.

Option 2: When the hostess went out, she suddenly remembered that she had locked her key at home.

Option 3: The hostess is about to be locked up in the tower, and she will take a last look at the world with the attitude of death.

The correct answer is the last one.

But the first two options seem to be more in line with Yukee Chen”s eyes at this time.

Therefore, many netizens complained that Yukee Chen’ Yan value, the heroine, was online, but her acting skills were dull and she stared like two bells, which made people very dramatic.

The netizen said that he thought that the hostess’s hip-pulling performance could be made up by Dylan, but he never imagined that he also overturned the car.

It may be that his role in "Freesia" is so amazing that Xiao Duo’s role is eclipsed.

Everyone knows that Dylan’s face is the most attractive thing. I don’t know whether it’s a stylist’s standard or a character setting. The hat Dylan wears on his head makes him look a little strange.

Coupled with a purple costume and a makeup that doesn’t match, I have to say that this makeup was shot at some death angles, which greatly reduced the handsome degree of Yue Zun’s adult.

In terms of acting skills, netizens commented that Dylan was too dull. In many plots, he prefers to talk with his neck stuck. Moreover, only the male and female actors are dubbing in the whole play.

02 Lucky Resource Coffee?

In others’ eyes, Dylan seems to be a very lucky existence in the entertainment circle, and some even call him Resource Cafe. But looking back on Dylan’s career, he has actually been working hard. After all, it’s so hot now. If we only rely on luck, Dylan probably won’t be where he is today.

Dylan once participated in the reality show variety Superdimensional Idol and starred in the mainland versions of Meteor Garden and Night Two, but none of them aroused much splash.

Until then, I took the play yu long. The heat was there at that time, but it was a uniform stigma.

Dylan has become synonymous with the ugly man in ancient costume and acting skills, and the tucao video at a certain station has reached millions of broadcasts.

Even so, he took the characters seriously. During the broadcast of yu long, Dylan printed his book list on Weibo. It seems that I have thought a little bit about the plot. At the same time, this has also been questioned by netizens: Who knows if this is "pretending"?

There are also actresses who play against him, saying that he will recite the other party’s words in order to be more smooth and substitute.

There is no idol burden to participate in the variety show, and it also presents the scene of watermelon head’s fame.

Later, with the drama "Freesia Tactics", Dylan’s popularity increased, and the director also stood up and praised him.

After the fire, Dylan was as busy as a bee.

Take on a new play as the leading actor.

All kinds of attendance activities, invited to participate in the GQ ceremony of the red carpet shine.

Even the big show of luxury brand LV invited Dylan to be present.

But even so, he has no airs, and he still tries to seize the opportunity to advertise himself, asking the producers and directors to find their own films. This kind of Dylan can be regarded as a down-to-earth and real person.

In addition to acting in a down-to-earth manner and working hard, he is also a rare real person in private.

Dylan’s family is average, and his father sells fried skewers. Before that, he often went home to help his family sell fried skewers.

Even Eric Wang, who has always been serious, praised him on the show: "He is essentially a rare person in this era, and he goes straight to that kind …".

You have to speak with acting skills and works.

Looking back at the stars of entertainment flow, YiBo, Dylan, Leo, Zhao Lusi … Nowadays, one after another, the flow is rising, dividing up the cake of entertainment circle. When someone comes in, someone will eat less or go out. In fact, they are not disturbing the water in the pool, but to increase the vitality of the water in the pool, but the increase of one person’s flow will inevitably affect another person’s exit.

In addition, some netizens spit out that the status quo of entertainment artists is that they pull their legs on the stage, dance and paddle, get together and act, and they are not good at acting, doing things that they were not good at, and they can’t figure out their position. Therefore, the current traffic stars are still full of various controversies.

Chen Daoming, a veteran actor, once said at a symposium: The so-called stars are not from the literary and art circles, but from the traffic circle. They are plastic actors hyped by packaging. Although it is also active in this industry, it has affected the reputation and reputation of many excellent creators.

Indeed, it seems that the acting level and personal problems of the entertainment personnel still need to be improved. After all, the artists in the entertainment circle have subverted the public’s cognition again and again, so that we can’t see the bottom line of entertainment.

Nowadays, Dylan’s new drama "Floating Edge Map" has been launched, although the controversy continues, but the popularity has not diminished. There is also a modern drama "Taking Love as a Camp" to be broadcast. I don’t know what comments these follow-up netizens will give, but what is certain is that his challenge is still not small.

Dylan’s hope of becoming popular will not be just a flash in the pan, but how far he can go still depends on whether he can keep up with the works and enthusiasm in the future, and how he can keep it. Besides, there are still many voices questioning Dylan. If you want to prove your strength, you will ultimately depend on the quality of your works.

And his explosion has brought a lot of pressure to other artists. I hope everyone will not relax their vigilance, or they will work harder.

In a word, having the chassis depends on how Dylan will go in the future.

　　Recently, the Central Network Information Office, the Ministry of Agriculture and Rural Affairs, the National Development and Reform Commission, the Ministry of Industry and Information Technology, and the National Rural Revitalization Bureau jointly issued the Key Points of Digital Rural Development in 2022 (hereinafter referred to as the Key Points). The circular calls for adhering to the guidance of the Supreme Leader’s Socialism with Chinese characteristics Thought in the New Era, fully implementing the spirit of the 19th National Congress of the Communist Party of China and the previous plenary sessions of the 19th National Congress, thoroughly implementing the spirit of the Central Economic Work Conference and the Central Rural Work Conference, and conscientiously implementing the Opinions of the Central Committee of the Communist Party of China and the State Council on Doing a Good Job in Comprehensively Promoting Rural Revitalization in 2022, the Strategic Outline for the Development of Digital Villages, and the National Informatization Plan for the 14th Five-Year Plan. Give full play to the driving and empowering role of informatization in rural revitalization, accelerate the construction of a digital economic system that leads rural industrial revitalization, build a digital governance system that adapts to the development of urban-rural integration, constantly promote new progress in rural revitalization, and push the construction of digital China to a new step.

　　The "Key Points of Work" defines the work goal: by the end of 2022, new and greater progress will be made in the construction of digital villages. Digital technology has strongly supported the foundation of agriculture to be more stable, and the results of poverty alleviation have been further consolidated. The construction of rural digital infrastructure continued to advance, and 5G networks covered key towns and some key administrative villages. The Internet penetration rate in rural areas exceeded 60%. The rural digital economy has accelerated, the level of agricultural production informatization has steadily improved, and the retail sales of agricultural products e-commerce network has exceeded 430 billion yuan. The rural digital governance system has been continuously improved, the information service for the benefit of the people has been continuously deepened, farmers’ digital literacy and skills have been effectively improved, and the pilot construction of digital villages has achieved initial results.

　　The "Work Points" deployed 30 key tasks in 10 aspects. The first is to build a digital barrier to food security, including strengthening the monitoring of information on stable agricultural production and supply, and improving the digital level of farmland construction management. Second, continue to consolidate and improve the effectiveness of network assistance, including strengthening dynamic monitoring and assistance to prevent poverty, and optimizing and improving network assistance measures. The third is to speed up the filling of the shortcomings of digital infrastructure, including continuously promoting the construction of rural network infrastructure and promoting the digital transformation and upgrading of rural infrastructure. Fourth, vigorously promote the construction of smart agriculture, including consolidating the foundation of smart agriculture development, accelerating the digital transformation of agriculture, strengthening the supply of agricultural science and technology innovation, and improving the digital level of agricultural product quality and safety traceability. The fifth is to cultivate new formats of rural digital economy, including deepening the development of agricultural products e-commerce, cultivating and developing new formats of rural areas, strengthening rural digital financial services, and strengthening the information management of rural resource elements. Sixth, the prosperity and development of rural digital culture, including strengthening the construction of rural network culture positions and promoting the digitalization of outstanding rural cultural resources. The seventh is to improve the efficiency of rural digital governance, including promoting the intelligentization of rural party building and village management, improving the digitalization level of rural social governance, promoting the intelligentization of rural emergency management, and using digital technology to help rural epidemic prevention and control. Eighth, expand the digital service space for benefiting the people, including developing "Internet+education", "Internet+medical health", improving social security information services, deepening employment and entrepreneurship information services, and promoting rural consumption upgrading.The ninth is to speed up the construction of smart green villages, including improving the monitoring level of rural natural resources and ecological environment and strengthening the digital governance of rural human settlements. The tenth is to promote the construction of digital villages as a whole, including strengthening overall coordination and pilot construction, strengthening policy guarantee and financial services, and strengthening the construction of digital rural talents.

　　Key points of digital rural development in 2022

　　The year 2022 is a crucial year for comprehensively promoting rural revitalization and accelerating agricultural and rural modernization during the Tenth Five-Year Plan period. It is of special significance to stabilize the basic agricultural sector and do a good job in "agriculture, countryside and farmers". The development of digital villages should adhere to the guidance of the Supreme Leader’s Socialism with Chinese characteristics Thought in the new era, fully implement the spirit of the 19th National Congress of the Communist Party of China and the previous plenary sessions of the 19th National Congress, thoroughly implement the spirit of the Central Economic Work Conference and the Central Rural Work Conference, and conscientiously implement the Opinions of the Central Committee of the Communist Party of China and the State Council on Doing a Good Job in Comprehensively Promoting Rural Revitalization in 2022, the Strategic Outline of Digital Village Development and the National Informatization Plan of the 14th Five-Year Plan. Give full play to the driving and empowering role of informatization in rural revitalization, accelerate the construction of a digital economic system that leads rural industrial revitalization, build a digital governance system that adapts to the development of urban-rural integration, constantly promote new progress in rural revitalization, and push the construction of digital China to a new step.

　　I. Work objectives

　　By the end of 2022, new and greater progress will be made in the construction of digital villages. Digital technology has strongly supported the foundation of agriculture to be more stable, and the results of poverty alleviation have been further consolidated. The construction of rural digital infrastructure continued to advance, and 5G networks covered key towns and some key administrative villages. The Internet penetration rate in rural areas exceeded 60%. The rural digital economy has accelerated, the level of agricultural production informatization has steadily improved, and the retail sales of agricultural products e-commerce network has exceeded 430 billion yuan. The rural digital governance system has been continuously improved, the information service for the benefit of the people has been continuously deepened, farmers’ digital literacy and skills have been effectively improved, and the pilot construction of digital villages has achieved initial results.

　　Second, the key tasks

　　(A) to build a digital barrier to food security

　　1. Strengthen information monitoring of stable agricultural production and supply. Strengthen digital supervision in the field of grain purchase and sale, and speed up the construction of a digital supervision system with full coverage, whole chain and whole process of central and local governments. Establish and improve the market monitoring and early warning system of important agricultural products, and strengthen regulation and emergency support by classification and variety. Upgrade and improve the integrated platform of national and provincial agrometeorological services, promote the application of meteorological monitoring technologies such as satellite remote sensing and soil moisture data fusion, carry out refined agrometeorological disaster forecasting and early warning, and improve the ability of food safety meteorological services.

　　2. Improve the digital level of farmland construction management. Accelerate the establishment of a national comprehensive monitoring and supervision platform for farmland construction, improve the permanent basic farmland database, and build a "one map" of farmland construction in the country. Comprehensive use of satellite remote sensing and other monitoring technologies to strengthen the whole process monitoring and accurate management of high-standard farmland. We will further promote the national black soil protection project and explore the use of remote sensing monitoring and information management to supervise the quality of black soil cultivated land. Using satellite remote sensing images and information technology, we will strengthen the dynamic monitoring of "non-agricultural" and "non-grain" of cultivated land and permanent basic farmland throughout the country.

　　(2) Continue to consolidate and improve the effectiveness of network assistance.

　　3. Strengthen dynamic monitoring and assistance to prevent poverty. Improve and optimize the monitoring information system to prevent poverty, and include farmers who are at risk of returning to poverty and suddenly have serious difficulties in the monitoring scope. In view of the emerging problems found due to disasters, causes and epidemics, timely implement social assistance, medical security and other assistance measures. Promote the construction of dynamic monitoring information platform for low-income population, and strengthen the active discovery mechanism, dynamic monitoring and hierarchical classification assistance for rural low-income population.

　　4. Optimize and improve the network assistance measures. Increase support for the upgrading and transformation of broadband networks in poverty-stricken areas, especially in key counties for national rural revitalization. Continue to carry out accurate fee reduction for poverty-stricken households. Continue to promote the construction of key radio and television projects that benefit the people. Comprehensively improve the operational service level of agricultural and sideline products online sales platform in poverty-stricken areas and expand the sales scale of agricultural products in poverty-stricken areas. Using the new generation of information technology to consolidate and expand the achievements of ecological poverty alleviation. Encourage central enterprises to actively develop digital rural projects in poverty-stricken areas in combination with fixed-point assistance work, and strengthen infrastructure construction, innovation of operation mode and coverage of interest linkage. Relying on the action of "making every enterprise prosper every village", we will guide private enterprises to support the construction of digital villages in poverty-stricken areas. Give full play to the advantages of online letter enterprises and continue to carry out public welfare projects of digital village cohesion action.

　　(C) to speed up the completion of digital infrastructure shortcomings

　　5. Continue to promote the construction of rural network infrastructure. Continue to deepen the universal service of telecommunications and promote the breadth and depth coverage of rural optical fiber and 4G networks. Facing rural and remote areas with conditions and needs, we will gradually promote the construction of Gigabit optical fiber networks and accelerate the use of low frequencies to carry out rural 5G network coverage. Fill in the shortcomings of communication network facilities in border areas, and comprehensively use satellite communication and other access means to provide users with broadband network access services. Implement smart radio and television rural projects and continue to promote the special action of smart radio and television to serve rural revitalization.

　　6. Promote the digital transformation and upgrading of rural infrastructure. Further improve the digital management mechanism of rural roads and strengthen the construction of basic data statistics, collection and sharing mechanisms. Vigorously promote the construction of smart water conservancy, and continue to carry out digital twin basins and digital twin water conservancy projects. Accelerate the improvement of water conservancy infrastructure system in rural areas and promote the intelligent transformation of water conservancy infrastructure. Continue to implement rural power grid consolidation and upgrading projects to improve rural power supply reliability and power supply support capacity. Support business circulation, postal service and express delivery enterprises to strengthen the infrastructure construction of cold chain logistics in agricultural products producing areas and actively promote the informationization of cold chain logistics.

　　(D) Vigorously promote the construction of smart agriculture

　　7. Consolidate the foundation for the development of smart agriculture. Continue to promote the application of high-scoring satellite data in agricultural remote sensing. Actively promote the coverage of mobile Internet of Things in rural areas and increase the deployment of narrowband Internet of Things (NB-IoT) in agricultural production scenarios. Accelerate the construction and application of agricultural and rural big data, focus on building a national agricultural and rural big data platform, establish and improve the agricultural and rural data resource system, and build a "one map" of national agricultural and rural big data. Relying on the national seed industry big data platform, the database of agricultural germplasm resources was constructed. Further promote the construction of big data in the whole industry chain of single varieties of important agricultural products.

　　8. Accelerate the digital transformation of agriculture. Vigorously promote the application of digital breeding technology, build a digital breeding service platform, accelerate the transformation from "experience breeding" to "precision breeding", and gradually develop design breeding. Accelerate the application of information technology in agricultural production and operation, and improve the efficiency of agricultural production and operation. Strengthen the digital coordination of the whole grain industry chain, and promote the whole chain of grain production, purchase, storage and marketing. Improve the function of the national grain trading platform and develop mobile transactions. Accelerate the digital transformation of supply and marketing service outlets and build a comprehensive platform for "digital supply and marketing" to serve agriculture. Continue to do a good job in promoting the implementation, supervision and management of digital agriculture and rural projects, and further give play to the demonstration and leading role of agricultural and rural informatization demonstration bases.

　　9. Strengthen the supply of agricultural science and technology innovation. Strengthen the R&D and manufacturing of high-end intelligent agricultural machinery and equipment, and implement the national key R&D plan "Key technologies and intelligent agricultural machinery and equipment in factory farming" and "R&D and integrated application of common key technologies in rural industries". Using special support to adapt to a number of agricultural machinery and equipment such as rice planting machinery in southern hilly areas. Implement the subsidy policy for agricultural machinery purchase and application, and promote the application of Beidou intelligent terminal in agricultural production. Accelerate the preparation of the national agricultural machinery and equipment industry measurement and testing center. Build an information management service system for science and technology commissioners to improve their service efficiency.

　　10 to improve the quality and safety of agricultural products traceability digital level. Improve the national agricultural product quality and safety traceability management information platform. Continuously improve the traceability information system for organic product certification, and further optimize the public inquiry service of the certification information system for food and agricultural products. Guide leading grain processing enterprises and "China Good Grain and Oil" demonstration enterprises to carry out quality traceability. Accelerate the application of traceability platform for agricultural materials quality and safety in China, and build and improve the national cotton industry information platform.

　　(E) Cultivate new formats of rural digital economy

　　11. Deepen the development of agricultural products e-commerce. Further promote the project of "internet plus" agricultural products leaving the village and entering the city. We will continue to deepen the concept of "developing agriculture with a number of merchants", cultivate and promote online brands of agricultural products, carry out certification, funding and promotion of characteristic agricultural products, and promote the development of characteristic industries with branding. We will promote the work of postal express service for agricultural special products from villages to cities, cultivate modern agricultural demonstration projects for express service, build a demonstration zone for the coordinated development of rural e-commerce express delivery, and continue to promote the integrated development of transportation and postal express delivery. In-depth implementation of the youth rural e-commerce cultivation project, the formation of "Qingyun China" live broadcast to help agriculture alliance, and extensive "Qingyun China" live broadcast to help agriculture activities. We will continue to develop "women’s e-commerce" and cultivate industries that support women’s advantages and characteristics.

　　12. Cultivate and develop new rural formats. Strengthen the brand building of key villages and towns in rural tourism, and increase the online promotion of rural tourism brands. Improve the rural tourism monitoring system. Continue to hold the Yangtze River Delta Rural Cultural Travel Maker Conference to promote the effective combination of entrepreneurial innovation and rural revitalization. Promote the development of new Internet-based formats such as leisure agriculture, creative agriculture and adoption agriculture. Relying on China National Geographical Names Information Database, we will deepen the promotion of rural geographical names information service.

　　13. Strengthen rural digital financial services. Continue to promote the development of rural digital inclusive finance, and actively and steadily carry out the construction of inclusive finance Reform Experimental Zone. Increase the application and promotion of financial technology in rural areas, and accelerate the research and development of financial products suitable for the needs of farmers and new agricultural business entities. We will further promote the construction of rural credit system and continuously improve the coverage of credit. We will continue to promote the construction of rural payment service environment, promote online processing channels and fund collection services for central bank account business of rural financial institutions, and promote the sinking of mobile payment convenience services to rural areas in counties.

　　14. Strengthen the information management of rural resource elements. Improve the national, provincial, city, county and other interconnected rural land contract information application platforms, and steadily carry out online signing of rural land contract. Guide all localities to improve the online signing system of rural contracted land management rights transfer contracts, and improve the standardization and information management level of rural contracted land management rights transfer. Encourage all localities to establish a network trading platform for the transfer of rural contracted land management rights, and standardize services such as policy consultation, information release, contract signing, transaction verification, rights evaluation, financing guarantee, and file management. Explore the construction of rural homestead database and management information system.

　　(VI) Prospering and developing rural digital culture.

　　15. Strengthen the construction of rural network culture positions. We will continue to deepen the construction of county-level media integration centers and expand the coverage of public welfare projects for East-West cooperation and exchange in county-level media integration centers. Increase support for online audio-visual programs on the theme of agriculture, rural areas and farmers, and enhance the supply of high-quality content resources. Standardize the Internet religious information service, strengthen the supervision and disposal of harmful information on the Internet in rural areas, and vigorously publicize the party’s religious work theory, principles and policies. We will continue to carry out various special actions such as "Clean Net" and "Clear Lang" to create a safe and healthy network environment for children in rural areas.

　　16. Promote the digitalization of outstanding cultural resources in rural areas. We will strengthen the excavation and protection of outstanding traditional cultural resources in rural areas, further promote the key projects of the 14 th Five-Year Plan for the inheritance and development of Chinese outstanding traditional culture, and continue to promote the implementation of the national cultural digitalization strategy. We will continue to improve the construction of digital museums of famous historical and cultural towns and villages and traditional villages in China, and promote the implementation of ethnic village projects in Yunshang. Relying on the rural digital cultural relics resource library and digital exhibition, we will promote the digital permanent preservation and open utilization of rural cultural relics resources.

　　(7) Improve the efficiency of rural digital governance.

　　17. Promote the wisdom of rural party building and village management. Optimize and upgrade the modern distance education system for cadres in party member, and constantly improve the informationization and scientific level of rural grassroots party building work. Accelerate the full coverage of online government services at the provincial, city, county, township (town, street) and village (community) levels, strengthen the construction of city and county government service platforms, and provide accurate and refined government services for rural residents. Implement the village-level comprehensive service upgrading project to improve the informationization and intelligence level of village-level comprehensive services. Accelerate the construction of a comprehensive information management platform for rural housing, and improve the informatization level of rural housing construction management and service.

　　18. Improve the digital level of rural social governance. Explore and promote the new model of digital rural governance and expand the digital application scenarios of rural governance. Carry out standardization construction of grid service management, and deepen the construction of Zhi ‘an community and safe countryside. Continue to strengthen the networking application of video image system construction in rural public areas, and actively promote the in-depth application of video image resources in epidemic prevention and control, disaster prevention and mitigation, emergency management and other industries and fields. Continue to carry out the activities of "rural revitalization and rule of law", further promote the construction of public legal service platform, further strengthen the popularization and application of mobile intelligent mediation system, and accelerate the construction of a modern public legal service system covering urban and rural areas, which is convenient, efficient, equal and inclusive.

　　19. Promote the wisdom of rural emergency management. Improve the intelligent digital grid forecasting technology system, promote the accurate early warning signals of heavy rain and sudden strong convection in local areas to townships (towns and streets), and build an extreme weather monitoring and early warning service system. Relying on the integrated monitoring system of air, space and earth, strengthen disaster risk monitoring in rural disaster-prone areas. We will implement projects such as informatization of natural disaster monitoring and early warning, rapid reporting and early warning of national earthquake intensity, and strengthen early warning information services for remote rural areas, pastoral areas and mountainous areas. Continue to carry out publicity and education on disaster prevention and mitigation in rural areas.

　　20. Use digital technology to help rural epidemic prevention and control. Strengthen the monitoring of rural epidemic information, upgrade the communication big data platform, support the accurate prevention and control of rural normalized epidemic situation and the emergency response of local epidemic situation, and improve the accuracy and timeliness of regional investigation data. Promote national mutual recognition of health codes and one code communication. Make full use of the Internet, emergency broadcast terminals and other information means to carry out vaccination, epidemic prevention and control and other aspects of policy measures and knowledge popularization and publicity.

　　(8) Expanding the service space of digital benefiting the people.

　　21. Develop "Internet+Education". Accelerate the construction of new educational infrastructure, continuously improve the network construction of rural primary and secondary schools, and improve the network carrying capacity and service quality of primary and secondary schools. Through satellite TV and broadband network, high-quality educational resources are delivered to weak schools and teaching points in rural areas. Constantly improve the national public service system of digital education resources, strengthen the function of the national smart education platform for primary and secondary schools, and promote the cooperation between digital resources and the East. Continue to carry out special training and donation activities on educational informatization, and improve the educational informatization literacy of teachers and students in rural areas. We will continue to research and develop digital national common language learning resources, and continue to carry out research and development of national language informatization.

　　22. Develop "Internet+medical health". Build an authoritative, unified and interconnected national health information platform, and promote all kinds of medical and health institutions at all levels to be included in the regional national health information platform. Steadily promote the intensive cloud deployment of information systems in medical institutions. Promote the "Internet+Medical Health" and "Five Ones" service actions, continue to strengthen the construction of telemedicine service networks, and promote the sinking of quality medical resources. Guide local governments to explore the construction of grassroots digital health communities. Continue to promote the application service of electronic license and promote the joint office of "one thing is born". We will further promote the service of "internet plus Traditional Chinese Medicine" and deepen the popularization and application of the health information platform of the Chinese Medicine Museum. Accelerate the application of a unified national medical security information platform, and gradually establish an information sharing mechanism for medical expenses of patients. Before the end of 2022, at least one designated medical institution in each county will realize the direct settlement of medical expenses including outpatient expenses across provinces.

　　23. Improve social security information services. We will continue to improve the construction of a unified national social insurance public service platform, establish a "one-card" service for residents with social security cards as the carrier, further optimize rural grassroots social security services, and continuously expand the scope of services. Accelerate the popularization and application of the national social assistance system and promote the extension of social assistance services to the mobile terminal. We will broaden the service mode of "cross-provincial general office" for two subsidies for the disabled and promote the realization of "full-course network office". Increase the supervision function of the national information system of two subsidies for the disabled, and improve the accuracy of subsidies. Carry out the aging and barrier-free transformation of Internet websites and apps, and formulate the aging and barrier-free transformation plan for localized Internet applications.

　　24. Deepen employment and entrepreneurship information services. We will continue to improve the construction of employment information platform and strengthen the employment monitoring and analysis of poverty-stricken population, migrant workers, rural youth and other groups. Make full use of the internet platform to collect job information, and broaden the channels for farmers to go out for employment and find jobs nearby. Carry out vocational skills training for groups such as rural migrant workers and returning migrant workers, and support and help them find jobs and start businesses. Promote Internet enterprises to carry out Internet-assisted agricultural projects in rural areas, and open up new channels for farmers to increase their income.

　　25. Promote the upgrading of rural consumption. We will continue to implement county-level commercial construction, expand the coverage of rural e-commerce, improve the three-level logistics distribution system in counties and villages, and promote the expansion, upgrading and upgrading of rural consumption. Support large-scale commercial circulation enterprises, e-commerce platforms and other service enterprises to extend to rural areas, and accelerate brand consumption and quality consumption into rural areas. Accelerate the construction of rural delivery logistics system, promote the "express delivery into the village" project by classification, and promote the joint distribution of rural delivery logistics. Promote universal postal coverage in border villages. Guide traditional business circulation and postal enterprises to strengthen data-driven, promote digital product innovation, intelligent operation management and accurate service for agriculture, and support enterprises to accelerate digital and chain transformation and upgrading.

　　(9) Accelerate the construction of smart green villages.

　　26. Improve the monitoring level of rural natural resources and ecological environment. We will continue to organize the investigation and monitoring of natural resources, the construction of real-life three-dimensional China, and expand the construction of three-dimensional "one map" of natural resources, the basic information platform of land and space, and the application system of natural resources supervision and decision-making. Explore and promote the construction of national ecological monitoring, evaluation and early warning system, including rural areas. Accelerate the construction and application of forest and grass ecological network perception system, and promote the "real use and real connection" and "interconnection" of all related business systems of the perception platform. Promote the selection of national forestry and grass information demonstration zones.

　　27. Strengthen the digital governance of rural human settlements. Establish an online acceptance mechanism for rural human settlements, and guide rural residents to participate in the online supervision of human settlements through APP and small programs. Constantly improve the rural environmental monitoring system, and continuously strengthen the monitoring of environmental factors and key regulatory targets. Improve the monitoring capacity of water environment and water ecology in rural areas. Continue to strengthen the information management of rural domestic garbage collection, transportation and disposal, and improve the level of sewage and garbage treatment in villages and towns. Carry out the demonstration work of high-scoring satellite in the monitoring and application of rural human settlements.

　　(ten) to promote the construction of digital villages as a whole.

　　28. Strengthen overall coordination and pilot construction. Guide local governments to establish and improve the overall coordination mechanism for digital rural development, and promote the implementation of the Digital Rural Development Action Plan (2022-2025). Study and formulate the evaluation index system of digital rural development and carry out the evaluation of digital rural development. We will issue guidelines for the implementation of the digital village standard system and strengthen the standardization of digital villages. Continuously improve the guidelines for the construction of digital villages. Complete the summary and evaluation of the first batch of national digital village pilots, and encourage local governments to carry out regional digital village pilots. Make full use of the media, live broadcast platform, network audio-visual programs and other channels to tell the story of rural revitalization, sum up and promote typical experiences, and create a good social atmosphere.

　　29. Strengthen policy guarantee and financial services. Increase financial investment and guidance, make overall use of existing agriculture-related policies and funding channels in accordance with regulations, and support the construction of key digital rural projects. Strengthen financial institutions’ credit and financing support for key digital rural construction projects and high-quality agriculture-related enterprises, new agricultural business entities and rural employment and entrepreneurship groups. We will continue to increase the supply of rural finance and improve the adaptability of county credit funds throughout the country. Create a demonstration zone of financial services for rural revitalization and innovation according to local conditions. Continue to promote the demonstration project of financial technology to empower rural revitalization. Encourage local governments to explore the construction of a digital rural service resource pool and guide social forces to participate in the construction of digital villages in an orderly manner.

　　30. Strengthen the construction of digital rural talent team. Continue to carry out the training of farmers’ mobile phone application skills, organize network security education and training, and enhance the digital literacy and personal information protection awareness of rural population. We will continue to send strong staff to make good use of the first resident secretary and team, and strengthen the education and training on the application of modern information technology to rural party member cadres. Continue to strengthen the construction of new rural development research institutes in colleges and universities, and increase the supply of vocational education in areas where talents are urgently needed, such as agriculture and rural areas. Vigorously carry out information training for rural tourism talents, young talents in agriculture and rural science and technology, and compound talents.

Domestic Suzuki New Alto appeared in Beijing.

　　Recently, when Sohu netizens went to a 4S shop in Changan Suzuki for maintenance, they found a new Alto parked in the corner of the shop, which had been heated by major media. They walked over and observed it carefully, and found that the whole car was fine in workmanship, and the pink metallic paint was very bright. The teardrop-shaped headlights on the front of the car were the highlights of the whole car, which raised a lot of spirits for this car. The large-mouth grille follows the design idea of big brother Audi, but it has a lovely appearance on Alto’s little face. The Suzuki "S" chrome-plated logo on the big mouth is huge and eye-catching, which plays a finishing touch for this cute and playful little face.

Car side modeling dynamic fashion body length 3500mm.

　　The side shape of the car body feels familiar. The relatively long front door and short rear door are typical design ideas of a five-door mini-car. The lower edge of the window that rises all the way extends from the A-pillar to the C-pillar, which is dynamic and fashionable. However, due to the body length of 3500mm and the narrow rear door design, the rear door window has become a triangle-like shape. However, the domestic Alto of Changan Suzuki version is different from the European version. The rear door window does not use a low-cost negative pressure ventilation window, but is replaced by an electric lifting window to cater to the tastes of Chinese people, which greatly improves the convenience of use. The overall shape of the side of the car body is similar to that of Global Hawk Panda and BYD F0 listed earlier, which is fashionable and full of vigor.

　　The domestic new Alto’s wheelbase of 2340mm belongs to the middle and upper class among mini-cars, which is longer than that of Global Hawk Panda and BYD F0, and similar to that of Changan Benben of 2365mm. The body width of 1600mm is slightly narrower than that of competitors, and the height of 1470mm is basically the same as that of Panda and F0, and slightly shorter than that of Changan Benben.

Unique tail shape

The tailgate opening is slightly narrow and the trunk is shallow.

　　The shape of the rear part of the car body is unique, probably because the bumper is lifted to a higher position to protect the shorter car body, and the whole rear wall occupies about 2/5 of the rear of the car, which is very full. However, this design also brings inconvenience, that is, the opening of the tailgate becomes higher, and the fashionable three-dimensional crystal diamond combined taillights occupy a large area, which makes the opening of the tailgate narrow, the depth of the trunk is shallow, and it is difficult to enlarge something. The overall shape of the tail is avant-garde, and the logo of Changan Suzuki shows its domestic identity. The high-position brake lights are dotted on the small tail behind the roof, which not only attaches importance to safety but also does not lose fashion.

Design of front McPherson independent suspension and rear trailing arm independent suspension plus lateral stabilizer bar

　　In the aspect of suspension, the new Alto adopts the typical small car design of front McPherson independent suspension and rear trailing arm independent suspension plus lateral stabilizer bar, which saves cost and chassis space while ensuring certain comfort.

Alto adopts 155/65 R14 Jinhu tire and 8 aluminum alloy wheels

　　In terms of wheels, the new Alto high-profile model uses 14-inch 8 aluminum alloy wheels, which are fashionable in shape. 155/65 R14 Jinhu tire seems to be not very kind, and its main competitors are almost all 165 treads. The narrower tire reduces handling but has an advantage in fuel consumption.

　　Like domestic cars with the same price, New Alto is equipped with front disc and rear drum brakes, which is enough for cars with less than 1 ton.

　　Open the door and get into the car. Like Swift and SX4, the interior of the new Alto focuses on simple and fashionable routes, with the same color scheme as the mainstream sedan. The steering wheel shape makes people see at a glance that this is a Suzuki model, which is exactly the same as SX4 and Swift. It is made of PVC, but it looks very big in the petite cockpit of Alto, and it should be more harmonious if it can be designed with smaller points. The new Alto dashboard has a distinctive shape. The huge speedometer occupies the front of the driver’s line of sight. Under the orange background light, the automatic gear position is displayed, and all kinds of warning lights are arranged around the speedometer. On the LCD panel below, information such as clock, mileage and fuel gauge is integrated. The cancellation of the water thermometer shows Suzuki’s confidence in the product.

　　The highlight is the new Alto’s tachometer. On the dashboard in front of the driver’s line of sight on the left, a tachometer is independently designed, which is similar to BYD F0’s design, except that the new Alto’s instrument uses a red background light with a scarlet letter on a black background, which is very outstanding in modification style and adds features to the overall interior modeling.

　　Looking at the whole interior, the new Alto, as a joint venture model, has no outstanding advantages in terms of materials and equipment quality. Under the cost control, the overall level is close to that of domestic models. In terms of vehicle configuration, this experience is an automatic top-mounted vehicle. The gear shifting mechanism is the same as that of Swift, and the shape of the gear shifting base and handle is basically the same. Double airbags, ABS brakes, manual air conditioners, electric rearview mirrors, four-door electric windows with central door locks and remote control keys have become standard equipment for high-equipped vehicles, while four-speaker single-disc CD audio and AUX interface cater to the tastes of young people. The seat adopts manual 4-way adjustment, and the material is a combination of gray flannel and light leather material. In design, the front seat uses the integrated design of seat headrest and has the logo of ALTO, which makes it more comfortable to sit on, but the wrapping is not strong. The headrest of the rear seat is detachable, but the backrest is straight, so I’m afraid it’s uncomfortable to sit for a long time. The whole interior is mainly practical, and there are many necessary conveniences and equipment, while others can be saved. The interior made of plastic and flannel is basically in line with the market positioning of Alto, a mini car.

　　In terms of space, as long as the height is not higher than 185cm, the head space is still sufficient, while the leg space is slightly cramped. There is no problem in short-distance transportation in the city. If you are too tall for a long distance, you will feel bad.

　　It is understood that this car is a trial version of the model, and it is still quite different from the model listed later in the interior and engine compartment.

　　When the car is on fire when the sales are not available, I feel that the sound of ignition is fragile and light. During idling, the car vibrates very little. You even suspect that it uses a 3-cylinder engine, giving people the feeling of a high-end car. Suzuki K10B is really a good machine. Listen to the idling noise on the door. If the tachometer doesn’t point to 800 revolutions, I even doubt whether the engine is running. I found the secret of silence when I opened the hood. It turns out that the new Alto is there. On the nameplate below the car body, the engine power is written as 48Kw, and the compression ratio is reduced and adjusted compared with the previously publicized machine with 50Kw compression ratio of 11: 1. In order to adapt domestic Alto to the ration of 93rd gasoline, it is worthwhile to sacrifice some power.

Photo of old and new Alto

　　Due to the small space, I didn’t test drive for a short experience, but I was deeply impressed by the new Alto. Typical urban scooter and automatic transmission models are very suitable for shuttle in cities, and the 1.0L engine has obvious advantages in fuel consumption. In terms of energy saving and styling design, it has won the favor of many people. In September, the new Alto will be listed soon. In the highly competitive car market, the role of price guiding sales is very obvious. The new Alto has already occupied the absolute advantage of brand and reputation. So, can this old car sell well? Let’s wait for the price of the new Alto, and please continue to pay attention to Sohu Auto’s follow-up reports on the new Alto.

　　Copyright statement: This article is the exclusive manuscript of Sohu Auto, and the copyright belongs to Sohu Auto. It may not be reproduced without permission, and will be investigated once it is found.

　　

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