Foreword

Influenza virus can cause seasonal influenza, and may even cause a pandemic outbreak. Influenza virus is a negative-strand RNA virus with complex classification, numerous subtypes and easy mutation. At present, it is recognized that the best way to prevent influenza is vaccination. In order to ensure the effectiveness of the vaccine, the World Health Organization (WHO) updates the composition of the vaccine strain every year.

Changes of influenza vaccine strains in the northern hemisphere in 2024-2025

In order to keep the vaccine effective, it is necessary to update the components of influenza virus vaccine regularly. After analyzing the global influenza virus epidemiology, etiology and vaccine serology, WHO announced the recommendation of influenza vaccine components in the northern hemisphere from 2024 to 2025 on February 23, 2024.

?

Trivalent chicken embryo culture vaccine

an A/Victoria/4897/2022 (H1N1)pdm09-like virus

an A/Thailand/8/2022 (H3N2) -like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Trivalent cell culture or recombinant protein vaccine

an A/Wisconsin/67/2022 (H1N1)pdm09-like virus

an A/Massachusetts/18/2022 (H3N2)-like virus

a B/Austria/1359417/2021 (B/Victoria lineage)-like virus

?

Tetravalent chicken embryo and cell culture or recombinant protein vaccine

The following components are added on the basis of trivalent vaccine

a B/Phuket/3073/2013 (B/Yamagata lineage)-like virus

Since March 2020, the naturally occurring B/Yamagata virus has not been confirmed. WHO thinks that it is not necessary to use B/Yamagata virus as a component of influenza vaccine, and it should be removed from the component of influenza vaccine. Where tetravalent vaccine is still used, the composition of B/Yamagata line is consistent with the previous recommendation.

Comparing the composition of influenza vaccine in the northern hemisphere from 2023 to 2024, it was found that the change of composition was mainly due to the difference of H3N2 virus strains:

Vaccine types

2023-2024

2024-2025

Trivalent chicken embryo culture vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Thailand/8/2022 (H3N2) -like virus

Trivalent cell culture or recombinant protein vaccine

A/Darwin/9/2021 (H3N2)-like virus

A/Massachusetts/18/2022 (H3N2)-like virus

Recombinant antigen is the key material for vaccine research.

In influenza virus-related vaccines, drugs and even diagnostic reagents, key target antigens have played an important role. In the following table, we have sorted out the information of HA, NA and NP proteins.

albumen

function

app; application

HA

(hemagglutinin)

The sialic acid receptor on the host cell membrane binds to help the virus envelope fuse with the host cell membrane; Coagulation

Basic research on influenza

Influenza vaccine research and development

Development of anti-hemagglutinin antibody

Study on virus detection reagent

NA

(neuraminidase)

Hydrolyze sialic acid receptor to promote the release of mature virus particles

Research and development of antiviral drugs

Basic research on influenza

Influenza vaccine research and development

Antibody development

Study on virus detection reagent

NP

(nuclear protein)

Combine with influenza genetic material and participate in virus gene replication, transcription and translation; Maintain the stability of virus gene

Research and development of antiviral drugs

Basic research on influenza

Antibody development

Diagnostic product development

The recombinant antigen of influenza vaccine strain can be used in all aspects of vaccine development, such as vaccine content detection, vaccine biological titer detection and toxicological experimental research. Using recombinant antigen for ELISA detection, we can analyze the levels of serum total antibody and neutralizing antibody after vaccination, and use recombinant protein as control to detect the vaccine content.

The results of detecting the serum antibody level of mice immunized with vaccine by recombinant influenza HA protein (image from Andersen, et al.)

Influenza vaccine strain-related antigens are available in stock.

Yiqiao Shenzhou continues to pay attention to the research progress of influenza vaccine, and has built a relatively complete influenza virus research reagent library. It has been online to recombine some proteins of HA, NA and NP of the northern hemisphere influenza vaccine strain in 2024-2025, and it is available from stock. Order it now!

Consultation is polite!

After checking the information correctly, you can get a 35 yuan Luckin Coffee voucher.

Scanning code to understand the recombinant antigens related to components of influenza vaccine strains from 2024 to 2025;

references

[1]https://www.who.int/publications/m/item/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season

[2] Andersen, et al. Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief.[J]. Frontiers in Immunology.2021.747032.

[3] Bangaru S , et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface[J]. Cell, 2019.

[4] Kim M, et al. Inhibition of infection virus internalization by (-)-Epigallocatechin-3-gallate. [J]. Antiviral Research, 2013,100 (2): 460-472. Continue to slide to see the next one.

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(full) name gender Ticket number Examination department Apply for a position graduated institutions remarks Lu Yitong man 2013010100104 Provincial Commission for Discipline Inspection 201123773 First-level director and below Northwest university of political science and law Li Jiangbo man 2013010100109 Provincial Commission for Discipline Inspection 201123773 First-level director and below Northwest university of political science and law Zhou yongchao man 2013010100122 Provincial Commission for Discipline Inspection 201123773 First-level director and below Chinese people’s public security university Zhang Yu man 2013010100222 Provincial Commission for Discipline Inspection 201123773 First-level director and below Northwest university of political science and law Chai yuze man 2013010100229 Provincial Commission for Discipline Inspection 201123773 First-level director and below Fuzhou University Qiu Han man 2013010100409 Provincial Commission for Discipline Inspection 201123773 First-level director and below China University of Political Science and Law (CUPL) Qin wenjie man 2013010100417 Provincial Commission for Discipline Inspection 201123773 First-level director and below Longdong college Lei Yu man 2013010100502 Provincial Commission for Discipline Inspection 201123773 First-level director and below Northwest university of political science and law Wujiabo man 2013010100602 Provincial Commission for Discipline Inspection 201123773 First-level director and below Huazhong University of Science and Technology Li long man 2013010100617 Provincial Commission for Discipline Inspection 201123773 First-level director and below Hu’ nan Institute of Technology Chen Zhiwen man 2013010100618 Provincial Commission for Discipline Inspection 201123773 First-level director and below Northwest university of political science and law Sun Peng man 2013010100623 Provincial Commission for Discipline Inspection 201123773 First-level director and below Renmin University of China Pinghao man 2013010100702 Provincial Commission for Discipline Inspection 201123773 First-level director and below China University of Political Science and Law (CUPL) Wu shuaihong man 2013010101322 Provincial Commission for Discipline Inspection 201123774 First-level director and below Zhejiang University Zhang yang man 2013010101727 Provincial Commission for Discipline Inspection 201123774 First-level director and below Chang’an University Zhu Baoyuan man 2013010102323 Provincial Commission for Discipline Inspection 201123774 First-level director and below the central institute for correctional police Jamolan woman 2013010102411 Provincial Commission for Discipline Inspection 201123774 First-level director and below Beijing Jiaotong University Chang Jing woman 2013010102718 Provincial Commission for Discipline Inspection 201123774 First-level director and below China University of Political Science and Law (CUPL) Li Jin man 2013010103116 Provincial Commission for Discipline Inspection 201123774 First-level director and below Qingdao university Dangqiao woman 2013010103624 Provincial Commission for Discipline Inspection 201123774 First-level director and below Northwest A&F University Shang Jiaxin man 2013010103820 General office of provincial party Committee 201133775, the fourth-level director of the organ Xi’an University of Technology Sun zhenglong man 2013010103828 General office of provincial party Committee 201133776 Director of the fourth level of the organ Northwest university of political science and law Yang ruoyu woman 2013010103910 General office of provincial party Committee 201133777 Director of the fourth level of the organ Lanzhou Jiaotong University He Jing man 2013010104003 General office of provincial party Committee 201133778, the fourth-level director of the organ Shaanxi Normal University Xiong Yao woman 2013010104111 General office of provincial party Committee 201133779 Director, Level 4, Secrecy Office of Provincial Party Committee Xiamen University Qu dangping man 2013010104201 General office of provincial party Committee 201133780 Director of the Secrecy Office of the Provincial Party Committee Northwest University Law School Zhang bochao man 2013010104202 General office of provincial party Committee 201133780 Director of the Secrecy Office of the Provincial Party Committee Northwest university of political science and law Daisy woman 2013010104226 Propaganda department of provincial party Committee 201143781 Director of the Propaganda Department of the Provincial Party Committee Shenyang Aerospace University Luo beijuan woman 2013010104525 Propaganda department of provincial party Committee 201143782 Director of the Propaganda Department of the Provincial Party Committee Communication University of China Liu jieqiong woman 2013010104605 United Front Work Department of Provincial Party Committee 201153783, the first-level director of the Ministry and below Lanzhou university of technology Feng xinxing man 2013010104615 United Front Work Department of Provincial Party Committee 201153784, the first-level director of the Ministry and below China University of Political Science and Law (CUPL) Liu ruizhu woman 2013010104628 United Front Work Department of Provincial Party Committee 201153785, the first-level director of the Ministry and below Renmin University of China Zhang Chenchen man 2013010104723 United Front Work Department of Provincial Party Committee 201153786, the first-level director of the Ministry and below Shanghai University Dang Qiuxia woman 2013010104804 United Front Work Department of Provincial Party Committee 201153787 First-level director of the provincial party committee of the Agricultural Workers’ Party and below Shanxi University Han Jie man 2013010104818 United Front Work Department of Provincial Party Committee 201153788 First-level director and below of the Provincial Committee of Jiu San Society Lanzhou University Wang wenmiao man 2013010104905 United Front Work Department of Provincial Party Committee 201153789 Provincial Federation of Industry and Commerce, first-level director and below Baoji university of arts and sciences Mao chuhao man 2013010104906 Office of Foreign Affairs Working Committee of Provincial Party Committee 201163790 First-level director and below Beijing Foreign Languages University Yuan Wenting woman 2013010104922 Office of Foreign Affairs Working Committee of Provincial Party Committee 201163791 Provincial People’s Association for Friendship with Foreign Countries First-level Chief Staff and below Xi ‘ an international studies university Li yang man 2013010105004 Provincial Party Committee Organization Establishment Committee Office 201173792, the fourth-level director of the office. Chinese people’s public security university Saki Liu woman 2013010105015 Provincial Party Committee directly under the authority Workers’ Committee 201183793 First-level director and below yan’an university Zhou Zhendong man 2013010105022 Provincial Party Committee directly under the authority Workers’ Committee 201183793 First-level director and below CPC Shaanxi Provincial Party School Tian zhuowen woman 2013010105107 Provincial bureau of retired veteran cadres 201193794 [Civil Servant] First-level Chief Clerk and below Xi ‘ an international studies university Jiawei Zhang man 2013010105401 Provincial bureau of retired veteran cadres 201193795 [Civil Servant] First-level Chief Clerk and below xian university of science and technology high tech college John Chang man 2013010105425 Provincial Party History Research Office 201203796 [Reference Management] First-level Chief Clerk and below yan’an university Wang Kaixuan man 2013010105426 Provincial Party History Research Office 201203796 [Reference Management] First-level Chief Clerk and below yan’an university Liu Yitong woman 2013010105429 Provincial Party History Research Office 201203796 [Reference Management] First-level Chief Clerk and below Beijing Normal University Wang zhangzhang man 2013010105502 Provincial Party History Research Office 201203796 [Reference Management] First-level Chief Clerk and below Jilin University Huan Wang woman 2013010105511 Provincial Party History Research Office 201203796 [Reference Management] First-level Chief Clerk and below Wuhan University Zhang jiapei woman 2013010105512 Provincial Party History Research Office 201203796 [Reference Management] First-level Chief Clerk and below China West Normal University Louise Yang woman 2013010105527 Provincial archives 201213797 Department [Reference Management] Level 4 Chief Clerk and below Tibet University for Nationalities Long xiuping woman 2013010105627 Provincial archives 201213798 Department [Reference Management] Level 4 Chief Clerk and below Xidian University Antong man 2013010105805 Provincial archives 201213799 Post-warehouse Management Office [Reference Management] Level 4 Chief Clerk and below North China University of Technology Ai Jing woman 2013010105819 Provincial People’s Congress Standing Committee 201223800, the fourth-level director of the organ Southwest Politics and Law University Zhao Xiaoyu woman 2013010105912 Provincial People’s Congress Standing Committee 201223801, the fourth-level director of the organ Northwest university of political science and law Zhang Haodong man 2013010105915 Provincial People’s Congress Standing Committee 201223802, the fourth-level director of the organ Australian National University Fu Hui woman 2013010106010 Provincial People’s Congress Standing Committee 201223803 Director of the fourth level of the organ The University of Hong Kong aftereffect woman 2013010106106 Provincial Higher People’s Court 201233805 The second-level director of the agency and below South China Normal University Yaoyujing woman 2013010106119 Sheng women’s Federation 201243806, the fourth-level director of the organ university of leicester Wang mei woman 2013010106202 Provincial Red Cross Society 201253807 [Reference Management] First-level Chief Clerk and below Northwest University Geng liming man 2013010106301 Provincial Education Committee, Provincial Education Department 201263808, the fourth-level director of the organ Xi’an Jiaotong University Bai Peng man 2013010106306 Provincial Education Committee, Provincial Education Department 201263808, the fourth-level director of the organ yan’an university Hao wenzhuo woman 2013010106401 Provincial Education Committee, Provincial Education Department 201263809, the fourth-level director of the organ South China Normal University Huqi woman 2013010106519 Provincial Education Committee, Provincial Education Department 201263809, the fourth-level director of the organ University of Warwick, UK Xue Xiaoqiang man 2013010106529 Provincial Education Committee, Provincial Education Department 201263810 Provincial Education Examinations Institute [Reference Management] Level 4 Chief Clerk Shaanxi Normal University Liu rennan woman 2013010106616 Provincial Education Committee, Provincial Education Department 201263811 Provincial Education Examinations Institute [Reference Management] Level 4 Chief Clerk Southwest University Panjiali man 2013010106622 Provincial Education Committee, Provincial Education Department 201263812 Provincial Education Examinations Institute [Reference Management] Level 4 Chief Clerk Yunnan University He Yueyang woman 2013010106624 Provincial department of science and technology 201273814 First-level director and below Xi’an Jiaotong University Li Wenbo man 2013010106801 Provincial civil affairs department 201283816 The second-level director of the agency and below Qinghai University for Nationalities Qiao Fangyu man 2013010106925 Provincial finance department 201293819 Second-level chief clerk and below in government offices Lanzhou university of finance and economics Wang yinzhe man 2013010106928 Provincial finance department 201293819 Second-level chief clerk and below in government offices Xi’an University of Technology Gao Jiaxing woman 2013010107022 Provincial finance department 201293820 Second-level chief clerk and below in government offices The Central University Of Finance and Economics Yang Jingyan woman 2013010107102 Provincial finance department 201293820 Second-level chief clerk and below in government offices Northwest University Sun guangyan man 2013010107407 Provincial finance department 201293821 Second-level chief clerk and below in government offices Southwestern University of Finance and Economics Zhou Nan man 2013010107415 Provincial finance department 201293821 Second-level chief clerk and below in government offices North University of China Liu Jimei woman 2013010107514 Provincial finance department 201293822 Second-level chief clerk and below in government offices yan’an university Ma Rong woman 2013010107520 Provincial finance department 201293822 Second-level chief clerk and below in government offices Xi’an Jiaotong University Cao Jinbao man 2013010107606 Provincial finance department 201293823 Second-level chief clerk and below in government offices Shaanxi Normal University Cui qinqin woman 2013010107702 Provincial finance department 201293824 Second-level chief clerk and below in government offices Xidian University Wang Jiayue woman 2013010107725 Provincial department of natural resources 201303825 First-level chief clerk of Xixian New Area Natural Resources Bureau and below. Xi’an University of Architecture and Technology Tang Qi woman 2013010107820 Provincial water resources department 201313827 Provincial Water Conservancy Engineering Quality and Safety Center, Level 4 Chief Clerk Institutes Of Technology Of Changsha Deng Peng man 2013010107825 Provincial water resources department 201313828 Director of Level 4 of Provincial Water Conservancy Engineering Quality and Safety Center Hohai University Yang peina woman 2013010107917 Provincial Department of Agriculture and Rural Affairs 201323829 Third-level chief clerk and below in government offices. Chang’an University Chen Xue woman 2013010108009 Provincial Department of Agriculture and Rural Affairs 201323830 Provincial Rural Cooperative Economic Workstation [Reference Management] Level 4 Chief Clerk and below Southwestern University of Finance and Economics Yu Zhou man 2013010108021 Provincial Department of Agriculture and Rural Affairs 201323830 Provincial Rural Cooperative Economic Workstation [Reference Management] Level 4 Chief Clerk and below Northwest A&F University Yi Cai woman 2013010108118 Provincial Health and Wellness Commission 201333831 Director, Level 4, Provincial Health Supervision Center China Shiyou University (Beijing) Dan Li woman 2013010108122 Provincial Health and Wellness Commission 201333831 Director, Level 4, Provincial Health Supervision Center Xi’an University of Technology Wang Wen woman 2013010108210 Provincial Health and Wellness Commission 201333832 Director, Level 4, Provincial Health Supervision Center Beijing University of Chinese Medicine Changyibo man 2013010108501 Provincial Health and Wellness Commission 201333833 First-level Staff of Provincial Health Supervision Center shanxi medical university jinci college Luoganggang man 2013010108823 Provincial emergency management department 201343834 First-level Chief of the Comprehensive Coordination Department of Work Safety and below Beijing University of Chemical Technology Li yujia woman 2013010312510 Provincial emergency management department 201343835 First-level Chief of Science and Technology and Information Technology Division and below Peking University Qiao Shuyue woman 2013010109019 Provincial emergency management department 201343836 Provincial Flood Control and Drought Relief Security Center [Reference Management] First-level Chief Clerk and below china institute of water resources and hydropower research Max Zhang man 2013010109024 Provincial emergency management department 201343836 Provincial Flood Control and Drought Relief Security Center [Reference Management] First-level Chief Clerk and below Wuhan University Liu Jianwei man 2013010109130 Provincial audit office 201353837 First-level chief clerk and below in government offices Beijing National Accounting Institute Xi min woman 2013010109225 Provincial audit office 201353837 First-level chief clerk and below in government offices Chongqing University Huo xiaonan woman 2013010109322 Provincial audit office 201353838 First-level chief clerk and below in government offices Xi’an University of Architecture and Technology Villi woman 2013010109423 Provincial audit office 201353838 First-level chief clerk and below in government offices Chang’an University Jasmine Zhang woman 2013010109707 Provincial audit office 201353839 First-level chief clerk and below in government offices Xi ‘ an institute of finance and economics Liu Min woman 2013010109815 Provincial audit office 201353839 First-level chief clerk and below in government offices Xi’an Jiaotong University Gaohang man 2013010110027 Provincial audit office 201353840 First-level chief clerk and below in government offices Xidian University Yue Lu woman 2013010110014 Provincial audit office 201353840 First-level chief clerk and below in government offices Xi’an Technological University fill the vacancies in the proper order Anlang man 2013010110126 Provincial audit office 201353841 First-level chief clerk and below in government offices. Chang’an University Li Xin man 2013010110307 Provincial audit office 201353841 First-level chief clerk and below in government offices. Chang’an University Yang qiujun woman 2013010110316 Provincial Forestry Bureau 201363842 First-level Chief Clerk of Regulation Science and Technology Department and below Party School of the CPC Central Committee Derek lv woman 2013010110417 Provincial Forestry Bureau 201363843 First-level Director of Public Service Department and below Northwest A&F University Zhang Bin man 2013010110616 Provincial Forestry Bureau 201363844 First-level Chief Clerk of Provincial Forest Resources Administration and below southwest forestry university Liang yunpeng man 2013010110619 Provincial Forestry Bureau 201363845 First-level Chief Clerk of Provincial Forest Resources Administration and below Yunnan University Vencent Yang man 2013010110620 Provincial Forestry Bureau 201363845 First-level Chief Clerk of Provincial Forest Resources Administration and below Lanzhou University Wei qiuming woman 2013010110623 Provincial Forestry Bureau 201363846 First-level Chief Clerk of Provincial Forest Resources Administration and below Beijing Forestry University Su min woman 2013010110712 Provincial Forestry Bureau 201363847 First-level Chief Clerk of Provincial Forest Resources Administration and below Shaanxi Normal University Luo Ruijuan woman 2013010110723 Provincial Forestry Bureau 201363848 First-level Chief Staff of Provincial Forest Resources Administration and below Leeds University Huang Xiao woman 2013010110801 Provincial Forestry Bureau 201363850 First-level Chief Staff of Provincial Forest Resources Administration and below Chang’an University Li Jin woman 2013010110805 Provincial Forestry Bureau 201363850 First-level Chief Staff of Provincial Forest Resources Administration and below Xidian University Zhao shanling woman 2013010110821 Provincial radio and television bureau 201373851 Director of the Fourth Department of Provincial Radio and Television Bureau Southwest Politics and Law University Lei Jingxiang man 2013010110921 Provincial radio and television bureau 201373852 Director of the Fourth Department of Provincial Radio and Television Bureau Chang’an University Lawrence Wang man 2013010110924 Provincial radio and television bureau 201373852 Director of the Fourth Department of Provincial Radio and Television Bureau Xidian University Cao Yong man 2013010111001 Provincial statistics bureau 201383853 Third-level chief clerk of business office and below Tibet University for Nationalities Zheng Bo woman 2013010111004 Provincial statistics bureau 201383854 Third-level chief clerk of comprehensive office and below Hebei University Lv bingheng man 2013010111005 Provincial statistics bureau 201383855 Provincial Local Socio-economic Survey Center [Reference Management] Third-level Chief Clerk and below Queen’s University of Canada Jia Bei woman 2013010111014 Provincial statistics bureau 201383856 Provincial Local Socio-economic Survey Center [Reference Management] Third-level Chief Clerk and below Hebei University Zhang Chenyu woman 2013010111026 Provincial statistics bureau 201383857 Provincial Local Socio-economic Survey Center [Reference Management] Third-level Chief Clerk and below Korea Korea University Wang Jingyuan man 2013010111123 Provincial bureau of cultural relics 201393858 First-level director and below Shaanxi Normal University Tongkewei woman 2013010111201 Provincial bureau of cultural relics 201393859 First-level director and below xi’an shiyou university Chen yanru woman 2013010111212 Provincial poverty alleviation office 201403861 Provincial Poverty Alleviation Monitoring Center [Reference Management] First-level Director and below The Central University Of Finance and Economics Yin Hailei man 2013010111309 Provincial poverty alleviation office 201403862 Provincial Poverty Alleviation Monitoring Center [Reference Management] First-level Director and below Northeast university of finance and economics Chen Yuanyuan woman 2013010111408 Provincial poverty alleviation office 201403863 Provincial Poverty Alleviation Monitoring Center [Reference Management] First-level Director and below Northwest university of political science and law Zhao Peng man 2013010111415 Provincial poverty alleviation office 201403864 Provincial Poverty Alleviation Monitoring Center [Reference Management] First-level Director and below Northwest university of political science and law Ai Xinhua woman 2013010111505 Provincial local financial supervision and management bureau 201413865 Second-level chief clerk and below in government offices Xi’an Jiaotong University Yin yixuan woman 2013010111714 Provincial Grain and Material Reserve Bureau 201423867 Second-level Director and below Xidian University Wang herui woman 2013010111803 Provincial organ affairs service center 201433869 Personnel Department (Retiree Service Management Office) Level II Chief Staff and below University of Newcastle, UK Xu shuoqi man 2013010111808 Provincial organ affairs service center 201433870 Second-level Chief of the Commission for Discipline Inspection and below Shaanxi Normal University Wang jiao woman 2013010111814 Provincial organ affairs service center 201433871 Second-level Chief of Housing Management Office and below Qinghai University for Nationalities Feng yuru woman 2013010111828 Provincial organ affairs service center 201433872 Second-level Chief of Real Estate Management Office and below Northwest University Wang kaibo man 2013010111921 Provincial organ affairs service center 201433873 Second-level Chief of Energy Conservation Management Office of public institutions and below brunel university Jet Chao man 2013010111923 Provincial organ affairs service center 201433874 Second-level Chief Staff of Security Department and below Xi ‘ an university of posts and telecommunications Sun Xiaoqian woman 2013010111928 Provincial organ affairs service center 201433875 Director II of Infrastructure Engineering Management Office and below Xi’an University of Architecture and Technology Ma Lin woman 2013010112002 Provincial organ affairs service center 201433876 Director II of Infrastructure Engineering Management Office and below Chang’an University Huiyu woman 2013010112006 Provincial organ affairs service center 201433877 The second-level director of Fengcheng Management Center of provincial organs and below Xi ‘ an university of science and technology He Lu woman 2013010112011 Provincial organ affairs service center 201433879 The second-level director of Xingqing Veteran Cadres Service Management Office of provincial organs and below. Chinese Marine University Li Jiaojie woman 2013010112015 Provincial organ affairs service center 201433880 The second-level director of Xiaozhai Veteran Cadres Service Management Office of provincial organs and below Xi’an University of Technology Li Ning woman 2013010112018 Provincial organ affairs service center 201433882 Second-level Chief of the Office of the Provincial Committee for the Care of the Next Generation and below Xi’an Jiaotong University Shimin woman 2013010112023 Sheng supply and marketing cooperatives head office 201443883 Department Office [Reference Management] Level 4 Chief Clerk The Central University Of Finance and Economics Li jingman woman 2013010200103 Sheng supply and marketing cooperatives head office 201443884 Department Office [Reference Management] Level 4 Chief Clerk Xi ‘ an university of science and technology Zhang daiyue woman 2013010200109 Sheng supply and marketing cooperatives head office 201443885 Department Office [Reference Management] Level 4 Chief Clerk Northwest university of political science and law Zhang ningyi woman 2013010200121 Provincial court system 201453886 Assistant Judge of Xi ‘an Railway Transportation Intermediate Court Xi’an Jiaotong University Rui Hu woman 2013010200207 Provincial court system 201453887 Assistant Judge of Xi ‘an Railway Transport Court Renmin University of China slowly woman 2013010200221 Provincial court system 201453887 Assistant Judge of Xi ‘an Railway Transport Court Lanzhou University Pan Lei man 2013010200306 Provincial court system 201453888 Assistant Judge of Xi ‘an Railway Transport Court Tongji University Longdihui man 2013010200309 Provincial court system 201453888 Assistant Judge of Xi ‘an Railway Transport Court Southwest Politics and Law University Hu Juan woman 2013010200315 Provincial court system 201453889 Assistant Judge of Ankang Railway Transport Court Northwest university of political science and law Min Feng woman 2013010200407 Provincial court system 201453889 Assistant Judge of Ankang Railway Transport Court Northwest university of political science and law Liu Xiaoqian woman 2013010200410 Provincial court system 201453889 Assistant Judge of Ankang Railway Transport Court sichuan police college Chen Ruixiang man 2013010200421 Provincial court system 201453890 Assistant Judge of Ankang Railway Transport Court Xi’an Polytechnic University Xiong cheng man 2013010200424 Provincial court system 201453890 Assistant Judge of Ankang Railway Transport Court Chang’an University Li Yinxia woman 2013010200506 Provincial procuratorate system 201463891 Assistant Prosecutor of Xi ‘an Railway Transport Procuratorate Guangdong Polytechnic Normal University He Qian woman 2013010200511 Provincial procuratorate system 201463892 Assistant Prosecutor of Xi ‘an Railway Transport Procuratorate Northwest university of political science and law Zhao Xuesong woman 2013010200604 Provincial procuratorate system 201463893 Assistant Prosecutor of Xi ‘an Railway Transport Procuratorate Northwest university of political science and law Zhang liqian woman 2013010200626 Provincial procuratorate system 201463893 Assistant Prosecutor of Xi ‘an Railway Transport Procuratorate Northwest university of political science and law

Affected by this round of "refrigerator-level" cold wave, freezing rain and snow occurred in Lechang, Ruyuan and Nanxiong in Shaoguan City, which is located in the alpine mountain area of northern Guangdong Province, resulting in the interruption of many roads, among which the northern section of Shaoguan (Beijing-Zhuhai-North) of Beijing-Hong Kong-Macao Expressway was closed for more than 100 hours by noon on January 26th due to road icing and snow.

On the 30th, the reporter learned from the traffic police department of Shaoguan Expressway that although the traffic police department has separately diverted vehicles to Guangle Expressway at Ruyuan Toll Station Interchange in the northbound direction of Beijing-Zhuhai and Pingshi North Interchange (K5) in the southbound direction since the early morning of the 26th, there are still vehicles that "mistakenly entered" Beijing-Zhuhai North and stayed on the icy expressway.

On the morning of January 29th, Shaoguan high-speed traffic police found a large truck with Zhengzhou license plate in Henan parked on the expressway when they were inspecting the Beijing-Zhuhai North Bridge section which had been closed due to snow and ice. The traffic police came forward to ask and learned that the driver of the large truck "mistakenly broke into the restricted area" when passing through the traffic control section and drove to the icy section, so the vehicle could not move on and it was worth stopping on the road. The traffic police department immediately sent a batch of food and warm items for the drivers of large trucks to resist hunger and cold.

At noon on the 30 th, the road icing situation near the parking position of the big truck improved. The traffic police department immediately assisted the driver of the big truck to install anti-skid facilities and commanded the big truck to slowly reverse and leave the expressway.

On the morning of 29th, during an interview in Ruyuan Bridge Town, the reporter found that a car with Shenzhen number plate was parked on an icy uphill section of Bridge Town on G240 National Highway, and the windshield, rearview mirror and body were covered with a thick layer of ice and snow, and the car was empty. A triangular warning sign was placed about 30 meters behind the car, and the car was suspected to have been temporarily "abandoned" by its owner.

The roads with snow and ice are prone to traffic accidents. The picture shows the traffic police urgently handling the accident vehicles on Guangle Expressway.

The traffic police reminded the majority of car owners not to drive on ice and snow roads as much as possible, especially most Guangdong drivers who lack experience in driving on ice and snow roads. If they must drive on ice and snow roads, they should install snow chains as much as possible, and try to keep driving at a constant speed during the driving process. If there are wheel tracks in front of them, they can follow the rut; When the vehicle is accelerating, lightly step on the accelerator to prevent the driving speed from suddenly rising and slipping, or the two wheels encounter different resistances during the rapid acceleration, resulting in lateral sliding; Don’t hit the steering wheel when driving, slow down in advance when turning, and increase the turning radius appropriately to prevent sideslip.

At the same time, the traffic police reminded that because the friction of ice and snow pavement is smaller than that of dry pavement, it is necessary to increase the safe distance during driving to prevent rear-end collision. Don’t slam on the brakes when braking. The correct way is to "point the brakes" and use the engine to slow down the speed. When parking, park in a sheltered and flat place as far as possible. When parking on a slope road, it is necessary to prevent the car from slipping. Bricks or stones can be used to pad the bottom wheel position.

1905 movie network news From, to, almost every summer, there will be a national ramble out of the tight encirclement. This year, the first film in the series of painting rivers and lakes — — The curse of the wind. After the trailer was released at Cannes Film Festival in 2014, five years later, The Wind Spell was finally produced and will be shown to the audience on July 13th. Let many fans sigh, and finally wait for you.

In the preview released this time, Xia Lan used the five elements of gold, wood, water, fire and earth to fight fiercely with fierce beasts. According to legend, only the power of wind can compete with it, revealing the meaning of the title "Wind Spell" and setting up a world view full of Chinese style. In the poster released together, the young volley confronted the huge gluttony, revealing a stirring story of the rise of a young hero.

　

The most valuable guoman IP　The Wind Spell permeates the national wind into every detail.

From its first broadcast in 2012 to the present, the painting rivers and lakes have created many high-quality comic dramas, such as Xia Lan, Bad Man, Soul Master, Cup Don’t Stop, and Changed Students, which can be said to be the most cosmopolitan and vital national comic, and also regarded as the most valuable national comic IP in the industry. Therefore, the first movie of painting rivers and lakes was placed high hopes by anime fans to help the rise of the country.

In the preview, the mythical gluttony in this world, Xia Lan uses the power of five elements to compete, and the teenager wants to be a hero when he enters the rivers and lakes … … The setting of the whole world outlook in the Wind Mantra is full of Chinese style. The same is true of the details. Fierce beasts, which are mostly composed of curved designs, and rivers and lakes in noisy streets are trying their best to convey an oriental aesthetics, which conforms to the audience’s imagination of "national ramble". Director Liu Kuo almost "digs" these details to the extreme. "Let the China audience like it first and see it comfortably."

　

Hold back the movie dream for six years and develop the only domestic animation engine.　"grab back" some audiences for Guoman

The completion of the Wind Spell took five years of preparation and three years of production. But the time behind it is far more than that. In the mind of director Liu Kuo, this movie dream has been held back for too long. "Although I had a dream of making movies long ago, I still held back. I want to make myself strong first. Because the country in my heart is made by ourselves. "

With this in mind, director Liu Kuo and the team started to develop a "Datura Engine" for animation. After six years of "darkness before dawn", China’s 3D animation finally has the original ability of the whole process. After tens of thousands of minutes of animation polishing, "Wind Spell" was finally launched. The film is about to be released, and Liu Kuo revealed his hope that "in the case that the China market has been occupied by Hollywood and Japanese animation for a long time, we can win back some audiences for domestic animated films in China"!

On November 27, 2009, Cai Jian [2009] No.853

　　

Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Sichuan, Guizhou, Yunnan, Tibet, Heilongjiang, Jilin, Inner Mongolia, Liaoning Province (autonomous regions and municipalities directly under the Central Government) Finance Department (bureau), Grain Bureau, China Grain Reserve Management Corporation, COFCO Group Co., Ltd., China Hualiang Logistics Group Company,

　　In order to give full play to the role of market mechanism, stabilize the domestic corn market price, and protect the interests of grain farmers, with the approval of the State Council, after the newly-produced corn in Northeast China (including Heilongjiang, Jilin, Liaoning and Inner Mongolia, the same below) was listed in 2009, the central government gave a one-time fixed-fee subsidy to the southern feed-consuming provinces that purchased the newly-produced corn in Northeast China and transported it to the local area. In order to do a good job in subsidy management, we hereby print and distribute the Measures for Financial Management of Subsidies for New Corn Production in Northeast China in 2009 to you, please implement them carefully.

　　Attachment: Financial Management Measures for Subsidies of New Corn Production in Northeast China in 2009 by Southern Feed Consumption Provinces

　

　　Cc: General Office of the State Council, Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Sichuan, Guizhou, Yunnan, Tibet, Heilongjiang, Jilin, Inner Mongolia, Liaoning (autonomous regions and municipalities directly under the Central Government) People’s Government, Development and Reform Commission, Agricultural Development Bank branches, and the Ministry of Finance in Beijing, Shanghai and Inner Mongolia.

　　

Attachment:

Southern feed consumption provinces purchase new corn produced in Northeast China in 2009.

Measures for the financial management of expense subsidies

　　

　　In order to give full play to the role of market mechanism, stabilize the domestic corn market price, and protect the interests of grain farmers, with the approval of the State Council, after the newly-produced corn in Northeast China (including Heilongjiang, Jilin, Liaoning and Inner Mongolia, the same below) was listed in 2009, the central government gave a one-time fixed-fee subsidy to the southern feed-consuming provinces that purchased the newly-produced corn in Northeast China and transported it to the local area. To this end, these measures are formulated.

　　I. Scope of subsidies

　　(1) The southern feed consumption provinces include 16 provinces (autonomous regions and municipalities) such as Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Sichuan, Guizhou, Yunnan and Tibet.

　　(II) Under the leadership of the provincial people’s government, the local grain reserve companies and corn feed processing enterprises in the above-mentioned provinces are entrusted by the provincial grain administrative department and the financial department to purchase the newly-produced corn in China in 2009 in Northeast China under the principle of voluntary and independent declaration and at their own risk, and each province (autonomous region, city) entrusts 1-2 enterprises with the qualification of grain operation, and then uniformly transports them back to the local area and applies for subsidies. The list of specific enterprises should be announced to the public in a timely manner.

　　(III) The corn purchased by the grain enterprises directly under the central government (including the enterprise headquarters) in the above-mentioned provinces in the northeast and transported back to the above-mentioned provinces, as well as the corn purchased by the central reserve enterprises in the above-mentioned provinces from the northeast and used for reserve rotation, enjoy the same subsidy policy. The specific enterprise list shall be examined and determined by the enterprise headquarters, and the enterprise headquarters shall uniformly organize and apply for subsidies.

　　(four) the relevant provinces and enterprises directly under the central government shall report to the Ministry of Finance, the State Grain Bureau and other relevant departments for the record after selecting and determining the specific enterprise list; The State Grain Bureau shall make a summary and make it public in time. Once the list of enterprises is published, it will not be adjusted.

　　Second, the subsidy conditions and standards

　　(five) enterprises included in the scope of subsidies shall meet the following conditions when applying for subsidies:

　　1 enterprises entrusted by the provincial administrative department of food jointly with the financial department shall have the qualification of food business and the entrustment documents jointly issued by the local provincial food and financial departments. Grain enterprises and reserve enterprises directly under the central government need to be audited and confirmed by the enterprise headquarters.

　　2. The price purchased by enterprises from farmers in Northeast China shall not be lower than 0.76 yuan/kg in Inner Mongolia and Liaoning, 0.75 yuan/kg in Jilin and 0.74 yuan/kg in Heilongjiang (third class in the national standard, the same below). When purchasing third-class corn higher or lower than the national standard, the purchase price can be raised or lowered by 0.02 yuan/kg for each grade raised or lowered according to the national standard.

　　3. The purchased corn must be the newly produced corn in China in 2009.

　　4. The procurement period for enjoying the expense subsidy is from December 1, 2009 to April 30, 2010.

　　5. The purchased corn must be delivered to this province (autonomous regions and municipalities) before June 30, 2010.

　　6 enterprises applying for subsidies must be consistent with the goods receiving unit of the transport certificate.

　　7. The total amount of corn purchased by the central reserve enterprises applying for subsidies shall not exceed the reasonable annual rotation plan for the local subsidy period issued by the relevant state departments and China National Grain Storage Corporation.

　　(VI) The corn actually purchased by the enterprise according to the above provisions and transported back to the province (autonomous regions and municipalities) shall be subsidized by the central government at a one-time fixed cost of 0.035 yuan per catty according to the number of corn converted into standard products (moisture ≤14% and impurities ≤1%). The subsidized corn is sold by the enterprise itself and is responsible for its own profits and losses.

　　(seven) enterprises included in the scope of subsidies, one of the following acts, once found, cancel all financial subsidies of the enterprise, and through social media and other public notification:

　　1 enterprises will not yet arrived in the province (autonomous regions and municipalities) to apply for subsidies for corn.

　　2. The enterprise will apply for subsidies for the corn purchased within the non-subsidized procurement period or the corn newly produced in Northeast China in 2009.

　　3. The enterprise fails to submit the monthly statistical report of purchase, sale and storage to the local administrative department of grain according to the provisions of the statistical system, and the grain and oil processing enterprise fails to submit the statistical report of grain and oil processing industry according to the provisions, and refuses to report false statistical data.

　　4 other acts of obtaining state subsidies through fraud.

　　(eight) according to the monitoring results of the relevant state departments, when the price of corn directly purchased from farmers in Northeast China rose to an average of 0.8 yuan/kg (third-class national standard), the central government stopped subsidizing it.

　　Third, the starting and ending period of subsidy policy

　　(9) The subsidized corn shall be purchased in Northeast China from December 1, 2009 to April 30, 2010 and delivered to the provinces (autonomous regions and municipalities) where the grain purchasing enterprises are located before June 30, 2010.

　　(10) The procurement time shall be based on the time when the procurement contract is signed.

　　(eleven) the arrival deadline refers to the time of transportation to the province where the grain purchasing enterprise is located. According to the date indicated on the legal transportation documents, it is determined according to the following principles:

　　1. Direct inter-provincial railway transportation shall be based on the date when the goods arrive at the platform;

　　2. The combined transport of hot metal and public water shall be based on the date of arrival at the loading dock;

　　3. Direct road transportation shall be based on the date when the goods arrive at the destination.

　　Iv. application for subsidy funds

　　(12) Time of application. Enterprises enjoying this subsidy need to submit an application before July 15, 2010, and local procurement enterprises shall submit the subsidy application and valid vouchers to the provincial grain administrative department according to the above-mentioned prescribed time limit; Enterprises affiliated to the central government shall submit subsidy applications and valid vouchers to the enterprise headquarters. The subsidy application includes all materials for corn procurement and transportation, as well as the sales and inventory of corn transported back to the province (autonomous regions and municipalities).

　　(thirteen) the subsidy application materials include:

　　1. Voucher of purchasing link: For direct purchase from farmers in Northeast China, there should be a unified invoice (copy) for grain and oil purchase uniformly printed by the local tax department, and this invoice should have an audit stamp stamped by the tax department. Unified procurement from grain enterprises in Northeast China should have a legal procurement contract and a special invoice for local tax value-added tax (copy). A new grain certificate issued by the county-level grain administrative department or quality inspection unit where the purchase is located. At the same time, the purchaser of the small ticket or the buyer of the purchase contract must be the subsidy application enterprise announced by the State Grain Bureau to the public.

　　2. Vouchers for transport links: waybills and delivery vouchers uniformly printed by railway, transportation and shipping departments. Among them, the place of dispatch is Northeast China, the place of arrival is the subsidized province stipulated in these Measures, and the consignee is a subsidy application enterprise made public by the State Grain Bureau.

　　3. Payment voucher: the grain purchase voucher or bank remittance voucher printed by the tax department. Among them: the payer and the payee of the payment voucher must correspond to the buyer and the seller of the purchase contract; At the same time, the payment before June 30, 2010 must exceed 80% of the contract amount.

　　4. Sales inventory certificate: sales contract and special VAT invoice (copy), inventory statistics.

　　5 central reserve corn storage enterprises, but also need to provide the relevant state departments and China Grain Storage Corporation issued the annual rotation plan documents.

　　When applying for subsidies, all vouchers are provided with photocopies (which must be stamped with the official seal of the unit), but the applicant enterprise must keep the vouchers for verification. The application materials provided by the enterprise shall be registered and tabulated, and shall be responsible for the authenticity of all materials. At the same time, the enterprise shall keep all the original documents by itself, and the relevant departments shall conduct random inspection when auditing and checking.

　　V. Audit of subsidy funds

　　(fourteen) the audit of the application materials of local procurement enterprises. The provincial food department shall timely summarize, sort out and preliminarily examine the application materials for enterprise subsidies, and report them to the provincial finance department for review within 15 working days. The provincial finance department shall complete the review within 15 working days, and submit an application report for pre-allocation of subsidy funds to the central finance, and send a copy of the application report to the local financial Ombudsman office of the Ministry of Finance for examination and confirmation. The provincial food department and the financial department shall be responsible for the authenticity and completeness of the application materials of enterprises (after the preliminary examination by the provincial food administrative department in Tibet, the provincial financial department shall review and report on its own).

　　(fifteen) the audit of the application materials of enterprises directly under the central government. Enterprise headquarters shall, after timely summarizing, sorting out and preliminary examining the application materials for enterprise subsidies, submit an application report for pre-allocation of subsidy funds to the Ministry of Finance before the end of July 2010, and send a copy of the application report to the Office of the Financial Ombudsman of the Ministry of Finance in Beijing for examination and confirmation. The enterprise headquarters shall be responsible for the authenticity and completeness of the application materials of the directly affiliated enterprises.

　　(sixteen) the Office of the Financial Ombudsman shall, on the basis of the audit of the relevant departments at the provincial level and the headquarters of the enterprise, review the application materials, and at least select 1~2 enterprises for on-the-spot verification. The Office of the Commissioner shall submit the examination results to the Ministry of Finance within 30 working days after accepting the application report.

　　Six, the allocation of subsidy funds

　　(seventeen) the Ministry of Finance shall, according to the application report of subsidy funds submitted by the provincial financial department and the enterprise headquarters, allocate the amount of corn subsidies determined by the Office of the Financial Ombudsman and the subsidy standards. Subsidies from local enterprises are allocated by the central government to provincial financial departments; Subsidies from enterprises directly under the central government shall be allocated by the central finance to the enterprise headquarters.

　　(eighteen) after receiving the central financial allocation, the provincial financial department shall directly allocate it to the subsidy application enterprise within 10 working days.

　　VII. Supplementary Provisions

　　(nineteen) the subsidy funds allocated by the central government, as subsidy income, shall be managed and used by enterprises according to the current accounting requirements.

　　(twenty) business disputes, accidents, etc., which occurred during the subsidy period, shall be settled by the enterprise according to the relevant laws and regulations.

　　(twenty-one) enterprises included in the scope of subsidies must conscientiously implement national policies, accurately and timely fill in relevant statistical statements, and truthfully submit subsidy application materials according to regulations. Relevant regions and departments should earnestly perform their duties of supervision and inspection, and it is strictly forbidden to resort to deceit or falsely report the subsidy funds.

　　(twenty-two) the Ministry of Finance shall be responsible for the interpretation of these Measures.

　　On May 17, Fu Linghui, spokesperson of the National Bureau of Statistics, said in response to the latest population data that China is currently in a state of mild aging.

　　Fu Linghui said that there are some misunderstandings in the society, and many people think that China has entered a deeply aging society. In fact, there is a general understanding in the world that a country’s population over 60 years old accounts for more than 10% of the total population, and this country has entered an aging society. Between 10% and 20%, it is mildly aging, between 20% and 30%, it is moderately aging, and over 30% is severely aging. According to the census, the proportion of elderly people over 60 years old in China is 18.7%, which shows that China is still in a state of mild aging. (CCTV reporter Yang Yi Zhou Ling)