Affected by this round of "refrigerator-level" cold wave, freezing rain and snow occurred in Lechang, Ruyuan and Nanxiong in Shaoguan City, which is located in the alpine mountain area of northern Guangdong Province, resulting in the interruption of many roads, among which the northern section of Shaoguan (Beijing-Zhuhai-North) of Beijing-Hong Kong-Macao Expressway was closed for more than 100 hours by noon on January 26th due to road icing and snow.

On the 30th, the reporter learned from the traffic police department of Shaoguan Expressway that although the traffic police department has separately diverted vehicles to Guangle Expressway at Ruyuan Toll Station Interchange in the northbound direction of Beijing-Zhuhai and Pingshi North Interchange (K5) in the southbound direction since the early morning of the 26th, there are still vehicles that "mistakenly entered" Beijing-Zhuhai North and stayed on the icy expressway.

On the morning of January 29th, Shaoguan high-speed traffic police found a large truck with Zhengzhou license plate in Henan parked on the expressway when they were inspecting the Beijing-Zhuhai North Bridge section which had been closed due to snow and ice. The traffic police came forward to ask and learned that the driver of the large truck "mistakenly broke into the restricted area" when passing through the traffic control section and drove to the icy section, so the vehicle could not move on and it was worth stopping on the road. The traffic police department immediately sent a batch of food and warm items for the drivers of large trucks to resist hunger and cold.

At noon on the 30 th, the road icing situation near the parking position of the big truck improved. The traffic police department immediately assisted the driver of the big truck to install anti-skid facilities and commanded the big truck to slowly reverse and leave the expressway.

On the morning of 29th, during an interview in Ruyuan Bridge Town, the reporter found that a car with Shenzhen number plate was parked on an icy uphill section of Bridge Town on G240 National Highway, and the windshield, rearview mirror and body were covered with a thick layer of ice and snow, and the car was empty. A triangular warning sign was placed about 30 meters behind the car, and the car was suspected to have been temporarily "abandoned" by its owner.

The roads with snow and ice are prone to traffic accidents. The picture shows the traffic police urgently handling the accident vehicles on Guangle Expressway.

The traffic police reminded the majority of car owners not to drive on ice and snow roads as much as possible, especially most Guangdong drivers who lack experience in driving on ice and snow roads. If they must drive on ice and snow roads, they should install snow chains as much as possible, and try to keep driving at a constant speed during the driving process. If there are wheel tracks in front of them, they can follow the rut; When the vehicle is accelerating, lightly step on the accelerator to prevent the driving speed from suddenly rising and slipping, or the two wheels encounter different resistances during the rapid acceleration, resulting in lateral sliding; Don’t hit the steering wheel when driving, slow down in advance when turning, and increase the turning radius appropriately to prevent sideslip.

At the same time, the traffic police reminded that because the friction of ice and snow pavement is smaller than that of dry pavement, it is necessary to increase the safe distance during driving to prevent rear-end collision. Don’t slam on the brakes when braking. The correct way is to "point the brakes" and use the engine to slow down the speed. When parking, park in a sheltered and flat place as far as possible. When parking on a slope road, it is necessary to prevent the car from slipping. Bricks or stones can be used to pad the bottom wheel position.

1905 movie network news From, to, almost every summer, there will be a national ramble out of the tight encirclement. This year, the first film in the series of painting rivers and lakes — — The curse of the wind. After the trailer was released at Cannes Film Festival in 2014, five years later, The Wind Spell was finally produced and will be shown to the audience on July 13th. Let many fans sigh, and finally wait for you.

In the preview released this time, Xia Lan used the five elements of gold, wood, water, fire and earth to fight fiercely with fierce beasts. According to legend, only the power of wind can compete with it, revealing the meaning of the title "Wind Spell" and setting up a world view full of Chinese style. In the poster released together, the young volley confronted the huge gluttony, revealing a stirring story of the rise of a young hero.

The most valuable guoman IP　The Wind Spell permeates the national wind into every detail.

From its first broadcast in 2012 to the present, the painting rivers and lakes have created many high-quality comic dramas, such as Xia Lan, Bad Man, Soul Master, Cup Don’t Stop, and Changed Students, which can be said to be the most cosmopolitan and vital national comic, and also regarded as the most valuable national comic IP in the industry. Therefore, the first movie of painting rivers and lakes was placed high hopes by anime fans to help the rise of the country.

In the preview, the mythical gluttony in this world, Xia Lan uses the power of five elements to compete, and the teenager wants to be a hero when he enters the rivers and lakes … … The setting of the whole world outlook in the Wind Mantra is full of Chinese style. The same is true of the details. Fierce beasts, which are mostly composed of curved designs, and rivers and lakes in noisy streets are trying their best to convey an oriental aesthetics, which conforms to the audience’s imagination of "national ramble". Director Liu Kuo almost "digs" these details to the extreme. "Let the China audience like it first and see it comfortably."

Hold back the movie dream for six years and develop the only domestic animation engine.　"grab back" some audiences for Guoman

The completion of the Wind Spell took five years of preparation and three years of production. But the time behind it is far more than that. In the mind of director Liu Kuo, this movie dream has been held back for too long. "Although I had a dream of making movies long ago, I still held back. I want to make myself strong first. Because the country in my heart is made by ourselves. "

With this in mind, director Liu Kuo and the team started to develop a "Datura Engine" for animation. After six years of "darkness before dawn", China’s 3D animation finally has the original ability of the whole process. After tens of thousands of minutes of animation polishing, "Wind Spell" was finally launched. The film is about to be released, and Liu Kuo revealed his hope that "in the case that the China market has been occupied by Hollywood and Japanese animation for a long time, we can win back some audiences for domestic animated films in China"!

On November 27, 2009, Cai Jian [2009] No.853

Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Sichuan, Guizhou, Yunnan, Tibet, Heilongjiang, Jilin, Inner Mongolia, Liaoning Province (autonomous regions and municipalities directly under the Central Government) Finance Department (bureau), Grain Bureau, China Grain Reserve Management Corporation, COFCO Group Co., Ltd., China Hualiang Logistics Group Company,

　　In order to give full play to the role of market mechanism, stabilize the domestic corn market price, and protect the interests of grain farmers, with the approval of the State Council, after the newly-produced corn in Northeast China (including Heilongjiang, Jilin, Liaoning and Inner Mongolia, the same below) was listed in 2009, the central government gave a one-time fixed-fee subsidy to the southern feed-consuming provinces that purchased the newly-produced corn in Northeast China and transported it to the local area. In order to do a good job in subsidy management, we hereby print and distribute the Measures for Financial Management of Subsidies for New Corn Production in Northeast China in 2009 to you, please implement them carefully.

　　Attachment: Financial Management Measures for Subsidies of New Corn Production in Northeast China in 2009 by Southern Feed Consumption Provinces

　　Cc: General Office of the State Council, Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Sichuan, Guizhou, Yunnan, Tibet, Heilongjiang, Jilin, Inner Mongolia, Liaoning (autonomous regions and municipalities directly under the Central Government) People’s Government, Development and Reform Commission, Agricultural Development Bank branches, and the Ministry of Finance in Beijing, Shanghai and Inner Mongolia.

Attachment:

Southern feed consumption provinces purchase new corn produced in Northeast China in 2009.

Measures for the financial management of expense subsidies

　　In order to give full play to the role of market mechanism, stabilize the domestic corn market price, and protect the interests of grain farmers, with the approval of the State Council, after the newly-produced corn in Northeast China (including Heilongjiang, Jilin, Liaoning and Inner Mongolia, the same below) was listed in 2009, the central government gave a one-time fixed-fee subsidy to the southern feed-consuming provinces that purchased the newly-produced corn in Northeast China and transported it to the local area. To this end, these measures are formulated.

　　I. Scope of subsidies

　　(1) The southern feed consumption provinces include 16 provinces (autonomous regions and municipalities) such as Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Sichuan, Guizhou, Yunnan and Tibet.

　　(II) Under the leadership of the provincial people’s government, the local grain reserve companies and corn feed processing enterprises in the above-mentioned provinces are entrusted by the provincial grain administrative department and the financial department to purchase the newly-produced corn in China in 2009 in Northeast China under the principle of voluntary and independent declaration and at their own risk, and each province (autonomous region, city) entrusts 1-2 enterprises with the qualification of grain operation, and then uniformly transports them back to the local area and applies for subsidies. The list of specific enterprises should be announced to the public in a timely manner.

　　(III) The corn purchased by the grain enterprises directly under the central government (including the enterprise headquarters) in the above-mentioned provinces in the northeast and transported back to the above-mentioned provinces, as well as the corn purchased by the central reserve enterprises in the above-mentioned provinces from the northeast and used for reserve rotation, enjoy the same subsidy policy. The specific enterprise list shall be examined and determined by the enterprise headquarters, and the enterprise headquarters shall uniformly organize and apply for subsidies.

　　(four) the relevant provinces and enterprises directly under the central government shall report to the Ministry of Finance, the State Grain Bureau and other relevant departments for the record after selecting and determining the specific enterprise list; The State Grain Bureau shall make a summary and make it public in time. Once the list of enterprises is published, it will not be adjusted.

　　Second, the subsidy conditions and standards

　　(five) enterprises included in the scope of subsidies shall meet the following conditions when applying for subsidies:

　　1 enterprises entrusted by the provincial administrative department of food jointly with the financial department shall have the qualification of food business and the entrustment documents jointly issued by the local provincial food and financial departments. Grain enterprises and reserve enterprises directly under the central government need to be audited and confirmed by the enterprise headquarters.

　　2. The price purchased by enterprises from farmers in Northeast China shall not be lower than 0.76 yuan/kg in Inner Mongolia and Liaoning, 0.75 yuan/kg in Jilin and 0.74 yuan/kg in Heilongjiang (third class in the national standard, the same below). When purchasing third-class corn higher or lower than the national standard, the purchase price can be raised or lowered by 0.02 yuan/kg for each grade raised or lowered according to the national standard.

　　3. The purchased corn must be the newly produced corn in China in 2009.

　　4. The procurement period for enjoying the expense subsidy is from December 1, 2009 to April 30, 2010.

　　5. The purchased corn must be delivered to this province (autonomous regions and municipalities) before June 30, 2010.

　　6 enterprises applying for subsidies must be consistent with the goods receiving unit of the transport certificate.

　　7. The total amount of corn purchased by the central reserve enterprises applying for subsidies shall not exceed the reasonable annual rotation plan for the local subsidy period issued by the relevant state departments and China National Grain Storage Corporation.

　　(VI) The corn actually purchased by the enterprise according to the above provisions and transported back to the province (autonomous regions and municipalities) shall be subsidized by the central government at a one-time fixed cost of 0.035 yuan per catty according to the number of corn converted into standard products (moisture ≤14% and impurities ≤1%). The subsidized corn is sold by the enterprise itself and is responsible for its own profits and losses.

　　(seven) enterprises included in the scope of subsidies, one of the following acts, once found, cancel all financial subsidies of the enterprise, and through social media and other public notification:

　　1 enterprises will not yet arrived in the province (autonomous regions and municipalities) to apply for subsidies for corn.

　　2. The enterprise will apply for subsidies for the corn purchased within the non-subsidized procurement period or the corn newly produced in Northeast China in 2009.

　　3. The enterprise fails to submit the monthly statistical report of purchase, sale and storage to the local administrative department of grain according to the provisions of the statistical system, and the grain and oil processing enterprise fails to submit the statistical report of grain and oil processing industry according to the provisions, and refuses to report false statistical data.

　　4 other acts of obtaining state subsidies through fraud.

　　(eight) according to the monitoring results of the relevant state departments, when the price of corn directly purchased from farmers in Northeast China rose to an average of 0.8 yuan/kg (third-class national standard), the central government stopped subsidizing it.

　　Third, the starting and ending period of subsidy policy

　　(9) The subsidized corn shall be purchased in Northeast China from December 1, 2009 to April 30, 2010 and delivered to the provinces (autonomous regions and municipalities) where the grain purchasing enterprises are located before June 30, 2010.

　　(10) The procurement time shall be based on the time when the procurement contract is signed.

　　(eleven) the arrival deadline refers to the time of transportation to the province where the grain purchasing enterprise is located. According to the date indicated on the legal transportation documents, it is determined according to the following principles:

　　1. Direct inter-provincial railway transportation shall be based on the date when the goods arrive at the platform;

　　2. The combined transport of hot metal and public water shall be based on the date of arrival at the loading dock;

　　3. Direct road transportation shall be based on the date when the goods arrive at the destination.

　　Iv. application for subsidy funds

　　(12) Time of application. Enterprises enjoying this subsidy need to submit an application before July 15, 2010, and local procurement enterprises shall submit the subsidy application and valid vouchers to the provincial grain administrative department according to the above-mentioned prescribed time limit; Enterprises affiliated to the central government shall submit subsidy applications and valid vouchers to the enterprise headquarters. The subsidy application includes all materials for corn procurement and transportation, as well as the sales and inventory of corn transported back to the province (autonomous regions and municipalities).

　　(thirteen) the subsidy application materials include:

　　1. Voucher of purchasing link: For direct purchase from farmers in Northeast China, there should be a unified invoice (copy) for grain and oil purchase uniformly printed by the local tax department, and this invoice should have an audit stamp stamped by the tax department. Unified procurement from grain enterprises in Northeast China should have a legal procurement contract and a special invoice for local tax value-added tax (copy). A new grain certificate issued by the county-level grain administrative department or quality inspection unit where the purchase is located. At the same time, the purchaser of the small ticket or the buyer of the purchase contract must be the subsidy application enterprise announced by the State Grain Bureau to the public.

　　2. Vouchers for transport links: waybills and delivery vouchers uniformly printed by railway, transportation and shipping departments. Among them, the place of dispatch is Northeast China, the place of arrival is the subsidized province stipulated in these Measures, and the consignee is a subsidy application enterprise made public by the State Grain Bureau.

　　3. Payment voucher: the grain purchase voucher or bank remittance voucher printed by the tax department. Among them: the payer and the payee of the payment voucher must correspond to the buyer and the seller of the purchase contract; At the same time, the payment before June 30, 2010 must exceed 80% of the contract amount.

　　4. Sales inventory certificate: sales contract and special VAT invoice (copy), inventory statistics.

　　5 central reserve corn storage enterprises, but also need to provide the relevant state departments and China Grain Storage Corporation issued the annual rotation plan documents.

　　When applying for subsidies, all vouchers are provided with photocopies (which must be stamped with the official seal of the unit), but the applicant enterprise must keep the vouchers for verification. The application materials provided by the enterprise shall be registered and tabulated, and shall be responsible for the authenticity of all materials. At the same time, the enterprise shall keep all the original documents by itself, and the relevant departments shall conduct random inspection when auditing and checking.

　　V. Audit of subsidy funds

　　(fourteen) the audit of the application materials of local procurement enterprises. The provincial food department shall timely summarize, sort out and preliminarily examine the application materials for enterprise subsidies, and report them to the provincial finance department for review within 15 working days. The provincial finance department shall complete the review within 15 working days, and submit an application report for pre-allocation of subsidy funds to the central finance, and send a copy of the application report to the local financial Ombudsman office of the Ministry of Finance for examination and confirmation. The provincial food department and the financial department shall be responsible for the authenticity and completeness of the application materials of enterprises (after the preliminary examination by the provincial food administrative department in Tibet, the provincial financial department shall review and report on its own).

　　(fifteen) the audit of the application materials of enterprises directly under the central government. Enterprise headquarters shall, after timely summarizing, sorting out and preliminary examining the application materials for enterprise subsidies, submit an application report for pre-allocation of subsidy funds to the Ministry of Finance before the end of July 2010, and send a copy of the application report to the Office of the Financial Ombudsman of the Ministry of Finance in Beijing for examination and confirmation. The enterprise headquarters shall be responsible for the authenticity and completeness of the application materials of the directly affiliated enterprises.

　　(sixteen) the Office of the Financial Ombudsman shall, on the basis of the audit of the relevant departments at the provincial level and the headquarters of the enterprise, review the application materials, and at least select 1~2 enterprises for on-the-spot verification. The Office of the Commissioner shall submit the examination results to the Ministry of Finance within 30 working days after accepting the application report.

　　Six, the allocation of subsidy funds

　　(seventeen) the Ministry of Finance shall, according to the application report of subsidy funds submitted by the provincial financial department and the enterprise headquarters, allocate the amount of corn subsidies determined by the Office of the Financial Ombudsman and the subsidy standards. Subsidies from local enterprises are allocated by the central government to provincial financial departments; Subsidies from enterprises directly under the central government shall be allocated by the central finance to the enterprise headquarters.

　　(eighteen) after receiving the central financial allocation, the provincial financial department shall directly allocate it to the subsidy application enterprise within 10 working days.

　　VII. Supplementary Provisions

　　(nineteen) the subsidy funds allocated by the central government, as subsidy income, shall be managed and used by enterprises according to the current accounting requirements.

　　(twenty) business disputes, accidents, etc., which occurred during the subsidy period, shall be settled by the enterprise according to the relevant laws and regulations.

　　(twenty-one) enterprises included in the scope of subsidies must conscientiously implement national policies, accurately and timely fill in relevant statistical statements, and truthfully submit subsidy application materials according to regulations. Relevant regions and departments should earnestly perform their duties of supervision and inspection, and it is strictly forbidden to resort to deceit or falsely report the subsidy funds.

　　(twenty-two) the Ministry of Finance shall be responsible for the interpretation of these Measures.

　　Cctv newsNine times out of ten, life is not satisfactory, only a little joy.

　　The four children got what they wanted, and they all had their own places after the college entrance examination; Three families bumped into each other, experienced anxiety and pain, and finally gained their own little joy … The hit TV series Little Joy, which has been unhappy all the time, finally ushered in a relatively "satisfactory" ending.

　　Little Tao Hong, who hasn’t taken the role for many years, didn’t expect Little Joy to be so popular. At first, he didn’t want to take the role of "Song Qian". He just joined in with the mentality of helping, and only agreed after turning on the phone, not to make a strong comeback. "I don’t have a play, but I don’t have nothing to do every day. I’m busy." Since he married Xú Zhēng, Tao Hong Jr. has gradually faded out of people’s sight and devoted himself to his wife. After having a daughter in 2008, accompanying her to grow up day by day became the happiest thing for Tao Hong Jr.

　　It’s not easy to tidy up a home. It took 10 years to learn how to be a mother. After returning to the family, Tao Hong Jr. once again attracted attention with the image of such a paranoid mother and became the most discussed mother in Little Joy. The audience remembered that Tao Hong, who had a pair of peach eyes, had interpreted so many classic characters. She has been clever and charming in Black Eyes, Empty Mirror, Sunny Days and Pig with Bright Spring, and she never forgets anything.

　　Interestingly, on the one hand, he became famous too early and left the screen for too long, so that many young viewers didn’t know little Tao Hong at all; On the other hand, the image of "Song Qian", an unlovable but true "Chinese-style" mother, makes people see Tao Hong’s acting again. "I feel great, don’t know me, so I can ‘ Do whatever you want ’ Play more different roles. "

　　Not long ago, Christina’s speech at the FIRST Film Festival calling on directors and producers to give Mesozoic actresses a chance caused a heated discussion. The passive situation that the subject matter is far away, the role is missing, and the older actress has no play is once again put on the table. In "Little Joy", in addition to the formidable young actors, the excellent acting skills of six middle-aged actors are the quality guarantee of the whole play.

　　Tao Hong Jr. thinks that this is not something that a middle-aged actress can’t play in the final analysis, but something that the whole middle-aged women group is not concerned by the society. "Without corresponding attention, there will be no film and television works, and no works will tell them. Who will we play?" Nowadays, Tao Hong Jr. is more relaxed. He never picks up plays at random, and he doesn’t need to prove that he can act. If he has good works, he will come out and perform. With inner satisfaction and family harmony, Tao Hong Jr. no longer "competes" with herself, and the pressure and anxiety of middle-aged actresses do not exist here.

　　Yongmei and George W. Tao Hong are old acquaintances. It’s been 20 years since they first collaborated on Where Dreams Start to Little Joy. In the play, Yongmei’s gentle and intellectual mother "liujing" is not only in sharp contrast with Tao Hong’s tough mother "Song Qian", but also has a special friendship with Song Qian’s daughter "Eiko". Many viewers reported that they were often moved to tears by this unforgettable friendship between liujing and Eiko.

　　Making friends with a child, supporting each other and making progress is also Yongmei’s favorite counterpart. Playing mother is nothing new to Yongmei. In "Little Joy", Yongmei, who has never been a mother, just deduced the most ideal mother in the hearts of countless people, giving this role the most comfortable and appropriate appearance, and his acting skills can be seen.

　　Yongmei has always been the kind of actor whose audience is particularly familiar with but whose name is unknown. Liujing, who is as gentle as jade and generous in understanding, has more or less Yongmei’s own shadow. She often gives people the impression of extraordinary temperament. She speaks slowly and eloquently, and people and voices are very comfortable. It seems that seeing her will make her feel better.

　　After 23 years of debut, Yongmei, a non-trained actress, is not a prolific actress. In the entertainment industry, she is even less eager to achieve success and pursue fame and fortune. At the beginning of the year, it seems that the afterheat of Yongmei’s winning the first Berlin film in the mainland with Wang Xiaoshuai’s film Auld Lang Syne has just dissipated. Little Joy is so gentle that liujing in her bones is once again surrounded by powder, and Yongmei, who has always been low-key, has reached a new high in fans and attention, which has made everyone have new expectations for her.

　　The audience slowly understood her story. She has always maintained a cautious sense of alienation in the entertainment industry. After four years without filming, she once said, "I am waiting for the role that belongs to me. I am not in a hurry, so don’t worry." Yongmei, who is in no hurry, still has a temper when she has an opinion. When there is no filming, there are works to find her, and she can only play some unnecessary wife roles. "How to say, like a shelf without a soul." Yongmei refused.

　　"I also have times when I am not gentle, more stubborn and more individual, and sometimes when I am unreasonable." As long as it’s a good character, dynamic and touching, even if it’s repeated, Yongmei thinks it can be played. It’s not that she doesn’t feel the confusion of middle-aged actresses, especially in domestic scripts, which are always stereotyped and faceless, lacking all kinds of middle-aged female images. Therefore, when he meets a good role and cast, Yongmei cherishes it especially. There are some phenomena that she doesn’t agree with and can’t change, but she believes that the current situation that there is no market for powerful actors is slowly changing. At present, it is most important to be yourself.

　　Sha Yi had only eight episodes in Little Joy, and as a special actor, he was a veritable "supporting role". However, as soon as he appeared, "Qiao Weidong" who opened his mouth "Eiko, open the door, stay" contracted all the jokes of the audience. Sha Yi’s "Qiao Weidong" was originally an out-and-out "love rat" image, dressed in flowery shirts, whiskers and crew cut, and quickly won the title of "rustic old man".

　　You can feel the "greasy" of "Qiao Weidong" through the screen. However, it is such a father who is full of humor, afraid of his wife and loves his daughter, and has become the favorite of the audience among the three fathers. Some people say that just seeing Sha Yi’s face makes him want to laugh, and he is a man with his own jokes. With superb acting skills, Sha Yi has successfully promoted the role of "Qiao Weidong" to one of the important leading roles, and more and more scenes have been played.

　　Sha Yi, who had a childhood filter, frequently searched for Little Joy. The charming Bai Zhantang disappeared completely and was replaced by the good father "Old Joe" who knew, loved and cared for children.

　　Over the years, Sha Yi has never faded out of public view, but it seems that he has only done one thing, being a good father to Angie and Xiaoyu. Although not yet a son, Sha Yi, who relies on his two sons to perform variety shows frequently, teases himself that he has ushered in the second spring of his career, which makes him feel helpless.

　　Time is like killing a pig, getting fat and getting out of the dimple. It is hard for people to think that "Qiao Weidong" and "Bai Zhantang" are the same person in Sha Yi now. Legend of the Wulin is indeed the pinnacle of Sha Yi’s popularity and career, but since then, although he has played some roles intermittently, the audience’s impression of him still stays in "Bai Zhantang". Sha Yi seems to be used to it, too. It is much more difficult for him to be a father to his two sons and accompany them to grow up than to be an actor. He doesn’t mind being a green leaf in the family.

　　It is precisely because every character in the play is so lively and all the actors are acting online that "Little Joy" has left so many viewers wanting more. The actors we knew as children are no longer young or even forgotten by us, but when they appear, they are always warm and bright. Just as the director said, life is like "looking for sugar in glass slag" to "joy", and every grain is precious. (Text/Wang Jiaying)

Yu Xueyuan reminds

A new batch of influenza vaccine

Appointment vaccination has been opened.

Hurry up before the flu peak comes.

Arrange it for the children!

(Bao, it’s time for an injection)

Recently, a new batch (2023~2024 batches) of influenza vaccine has arrived in various places one after another, and it can be vaccinated by appointment.

On September 5th, China CDC suggested in the latest Technical Guide for Influenza Vaccination in China (2023-2024):

All people who are over 6 months old and have no contraindications should be vaccinated against influenza.

The CDC believes that

"This winter and next spring, you may face the risk of interaction or co-epidemic of respiratory infectious diseases such as COVID-19 and influenza."

In this situation, it is obviously necessary to vaccinate against influenza.

Is it too early to get a flu shot? How old can the child be vaccinated? How to choose several types of vaccines? ……There are still many concerns about the flu vaccine.

The following small series has compiled 9 frequently asked questions. Parents who are concerned about influenza vaccine should not miss today’s content ~

(Note: The new vaccination guide involves some updates and adjustments, and the following contents will also be popularized according to the new guide, so you may find that some information is different from what you have learned before, so it is recommended to take the new guide as the reference standard ~)

01

The flu vaccine is in place

Call now, is it early?

Say the answer first, not early, and just right.

Research data show that the epidemic season of influenza in winter and spring in China is usually from the middle and late October to the middle and early March of the following year.

After vaccination, the immune effect will not reach its peak until one month later.

According to the new guidelines: "The antibody protection level can be maintained for at least 6 months after influenza vaccination."

Vaccination now can just cover the upcoming peak of influenza in autumn and winter and the flu season in early spring next year.

When the flu peak comes, the antibody is just at the peak level, which can play a better protective effect.

02

The most important thing to vaccinate.

Who are they?

The new guidelines give priority to the timely vaccination of key and high-risk groups, including:

· Medical personnel, including clinical rescue personnel, public health personnel, health quarantine personnel, etc.;

·Older people aged 60 and over;

· People suffering from one or more chronic diseases;

· Vulnerable people and employees in old-age care institutions, long-term care institutions, welfare homes and other crowd gathering places;

· Pregnant women;

·Children aged 6-59 months (about 5 years old);

· Family members and caregivers of infants under 6 months old;

· People in key places such as kindergartens, primary and secondary schools, and supervision places.

Influenza vaccines are self-funded vaccines, but some areas have some free policies. Take Beijing as an example:

People over the age of 60, students in primary and secondary schools and emergency support personnel for major events can be vaccinated free of charge.

You can pay attention to the vaccination policy in your area.

03

What are the types of influenza vaccine?

How many shots? How to fight?

At present, there are trivalent inactivated influenza vaccine (IIV3), tetravalent inactivated influenza vaccine (IIV4) and trivalent live attenuated vaccine (LAIV3) approved for marketing in China, which are produced and supplied by different manufacturers.

In order to facilitate understanding, you can look at this table for specific vaccine types and applicable populations:

(Adults and children can refer to this table.)

Babies under the age of 6 months are also indirectly protected through the vaccination of their mothers during pregnancy and the vaccination of their caregivers and family members against influenza.

In order to gain sustained immunity,It is recommended that children be vaccinated against influenza once a year.Because the influenza virus is easy to mutate, the composition of the vaccine will be adjusted every year according to the prevalent strains of the year.

04

3 or 4, which is better?

Trivalent influenza vaccine can prevent influenza caused by influenza A (H1N1), H3N2 and Victoria B virus, while tetravalent influenza vaccine can alsoPrevent one more Yamagata virus B.

Source: Network

Although the virus coverage of tetravalent vaccine is wider than that of trivalent vaccine, the transmission ability and antigenic pathogenicity of influenza B virus are not as strong as that of influenza A virus.Therefore, vaccination with trivalent influenza vaccine can also prevent influenza virus.

There is no need for everyone to miss the best vaccination time in order to wait for the fourth price. After all,It is the most important thing to get vaccinated and protected in time!

05

Injection or nasal spray, which is better?

Whether it is injection or nasal spray, there is not much difference in safety and effectiveness.

You should notice that the injected vaccine is "inactivated" and the nasal spray is "attenuated". The difference lies in:

● Injection of influenza vaccine is to inactivate the virus, so that the virus loses its pathogenic ability but retains its antigenicity.

● Nasal spray vaccine is to culture and purify the live influenza virus, so that its virulence is weakened, but it can stimulate the human body to produce antibodies without pathogenic ability.

For babies who are very afraid of injections or dizzy needles, the nasal spray inoculation method is more moderate. But there is no need to pursue it deliberately. Again, timely vaccination is the most important thing.

06

The child has got the flu

Do you still need vaccination?

Need.

If the child accidentally gets the flu and has not been vaccinated against it before, he still needs to be vaccinated again after the baby gets better.

Because of influenza A,There is no cross-protection between different types.For example, if you have had H1N1 before, you will still get sick if you are infected with H3N2 next time.

07

Influenza vaccine can be combined with other vaccines

At the same time?

There are two situations.

Inactivated influenza vaccine (injection):Can be inoculated in different parts at the same time with other inactivated or attenuated influenza vaccines.

Attenuated vaccine (nasal spray):Can not be vaccinated with another attenuated vaccine at the same time, at least 4 weeks between them.

Can it be vaccinated at the same time as COVID-19 vaccine?

Over the age of 18, you can get inactivated influenza vaccine and COVID-19 vaccine at the same time;

Under the age of 18, it is recommended that the vaccination interval be greater than 14 days.

08

Taboos for influenza vaccination

Can egg allergy be vaccinated after all?

Egg allergy can be vaccinated against influenza.

People’s Republic of China (PRC) Pharmacopoeia (2010 edition, 2015 edition and 2020 edition) does not take people who are allergic to eggs as a taboo for vaccination.

The real vaccination taboos are the following!

You can’t get any flu vaccine.

(1) Those who are allergic to any ingredients contained in the vaccine (including auxiliary materials, formaldehyde, cracking agents and antibiotics) or have a history of severe allergic reaction to any kind of influenza vaccination.

(2) Patients suffering from acute diseases, severe chronic diseases or acute attacks of chronic diseases and fever are advised to be vaccinated after recovery or stable control.

(3) Guillain-Barre syndrome occurred within 6 weeks after previous influenza vaccination, which needs to be evaluated by a doctor.

Can’t be vaccinated with nasal spray attenuated influenza vaccine.

(1) Persons with low immune function due to drug use, HIV infection and other reasons.

(2) Children and adolescents treated with drugs containing aspirin or salicylic acid for a long time.

(3) Children with asthma aged 2-4 years.

(4) Have a history of Guillain-Barre syndrome.

(5) antiviral drugs such as oseltamivir and zanamivir were used 48 hours before inoculation, or palamivir was used 5 days before inoculation, or balosha was used 17 days before inoculation.

(6) In case of severe nasal congestion, it is suggested to suspend the inoculation of attenuated vaccine by nasal spray.

(7) Children with cochlear implants should avoid using nasal spray attenuated vaccine one week before and two weeks after operation.

(8) Pregnant women

There are still many contraindications for nasal spray attenuated vaccine.ofBefore choosing to vaccinate your child, you must pay attention to the above situation.

09

After vaccination

Will you still get the flu?

Maybe.

No vaccine can prevent the disease 100%, but vaccination can reduce the risk of infection andGreatly reduce the risk of serious illness and death.

According to the research data mentioned in the new guide, when influenza and COVID-19 are co-epidemic, after vaccination,At least it can achieve more than 70% protection effect.

Therefore, if no contraindications are involved, it is recommended to vaccinate in time, especially for the elderly and children.

Even if you are vaccinated against influenza, everyone should pay attention to prevention and maintain good hygiene habits.

Wash your hands frequently, ventilate frequently, go to crowded places less, wear masks when going to crowded places, and cover your nose and mouth when sneezing.

If you don’t know where to get a vaccine, you can refer to the following ways:

(1) Gaode or 114 inquires the telephone number of local hospitals, communities and epidemic prevention stations, and makes a phone call to consult about seedlings;

(2) Pay attention to WeChat official account, a local hospital, community and epidemic prevention station, and check whether there is an entrance for online seedling appointment;

（3）微信内搜索【疫苗服务预约】，选择所在城市，根据分类预约。

另外，育学园旗下北京弘和妇产医院也可约苗，在北京的朋友想了解可以拨打电话咨询??

咨询电话：(010)6549 1911

对流感疫苗还有其他问题，可以评论留言，小编会积极给大家解答~

最后，记得戳戳【在看】，和小编一起提醒大家，该！打！疫！苗！啦！

参考资料:

[1]中国疾病预防控制中心《中国流感疫苗预防接种技术指南（2023-2024）》

[2]上海疾控《流感疫苗可以安排了，给身体留出足够时间做准备》

[3]北京日报

免责声明：本文内容更新于2023年。文章仅提供一般的医疗、健康、用药、养育等方面的科普信息，不能代替任何个人的医学诊断和治疗。个人的医疗、用药问题请咨询医生。

授权转载：原创内容，欢迎转发，转载请留言。

01

这个孩子抹上脸的东西，可能导致性早熟！家里有的赶紧扔！

02

挨骂也要说，这种油别再吃了，家里有的赶紧扔！

03

扩散！这种家电每天都在释放「大量致癌物」！赶快提醒家里人

阅读原文」，下载育学园APP

　　Recently, various provinces and cities have successively disclosed the practical projects of people’s livelihood in 2025 and the provincial budget. According to statistics, up to now, more than ten provinces, including Beijing and Sichuan, have carried out or planned to carry out free vaccination programs for provincial-level female HPV vaccine.

　　According to the agency, with the successful completion of phase III clinical trials and the release of production capacity of HPV vaccine under research in China, the indications are extended to male population.ChinaThe market scale of HPV vaccine will continue to expand, and it is expected to reach 62.54 billion yuan in 2031.

　　Multi-provincial promotion

　　Since the beginning of this year, many provinces have indicated that they will launch a free vaccination program for HPV vaccine for school-age women.

　　Recently, Sichuan Province disclosed the "Report on the Implementation of the Budget in Sichuan Province in 2024 and the Draft Budget in 2025", which proposed to allocate 4.41 billion yuan for public health services. Improve the financial subsidy standard for basic public health services, support the implementation of "two cancers" free screening for school-age women, support the free vaccination of domestic bivalent HPV vaccine for eligible school-age girls, and increase support for AIDS prevention and treatment.

　　On January 26th, the General Office of the Beijing Municipal People’s Government issued the notice of "Important Livelihood Projects in Beijing in 2025", and Beijing will voluntarily vaccinate human papillomavirus vaccine for new girls in Grade One in 2025.

　　On January 10th, Tianjin Municipal Health and Health Commission formulated 16 measures to serve Tianjin Health and Health Kang Weimin in 2025, and explicitly launched the public welfare vaccination activities of reducing or exempting 450,000 doses of bivalent HPV vaccine for women aged 9-45.

　　In 2025, the work report of Yunnan provincial government put the implementation of "children’s health care and protection""Huimin Project" is listed as one of the 10 practical things to be done in 2025, and it is clearly put forward that domestic HPV vaccine should be vaccinated free of charge for eligible junior one girls in the province according to the principle of informed and voluntary.

　　In January this year, the government work report for 2025 released by Gansu Province made it clear that in 2025, we will continue to make overall arrangements for financial resources and do 10 practical things for the people, one of which is to subsidize HPV vaccination for 100,000 school-age girls on the premise of "knowing, volunteering and subsidizing".

　　In October 2024, National Health Commission held a press conference to disclose that since 2021, 11 provinces including Guangdong, Hainan, Fujian, Jiangsu, Jiangxi, Chongqing, Tibet, Zhejiang, Shandong, Hubei and Guangxi, as well as Zhengzhou,Chengdu and other cities have included HPV vaccination in the government’s practical projects for the people, and provided free HPV vaccination services for school-age girls aged 13-14 in the region through financial purchase services and fixed subsidies. Up to now, the policy of free HPV vaccination has covered about 40% of school-age girls in the country.

　　Speed up research and development

　　On January 8,It was announced that a number of new indications of tetravalent human papillomavirus vaccine (Saccharomyces cerevisiae) (trade name: Jiadaxiu, also known as tetravalent HPV vaccine) have been approved for marketing in National Medical Products Administration, which is suitable for male vaccination aged 9-26. This is the first HPV vaccine approved for male vaccination in China. Subsequently, many places announced the start of male HPV vaccination.

　　HPV infection is one of the most important public health problems in the world. Vaccination is the best way to prevent cervical cancer and other HPV-related cancers. Recently, in order to further respond to WHO’s Global Strategy for Accelerating the Elimination of Cervical Cancer, the International Papillomavirus Society needs to achieve the phased goal of "90-70-90" in 2030, and actively appeals to all countries to adopt a vaccination plan for both men and women as soon as possible, that is, to promote HPV vaccine equally to school-age boys and girls, so as to expand the coverage of vaccination and maximize the immune effect of the group.

　　Research and development of domestic nine-valent human papillomavirus vaccine is accelerated. A few days ago,It is said that the work of the phase III clinical study of the subsidiary Shanghai Zerun nine-valent HPV vaccine continues to advance. At present, the phase III clinical trial comparing the immunogenicity of this vaccine with similar vaccines is in the stage of data statistical analysis and writing clinical research reports. Based on the clinical development plan of nine-valent HPV vaccine products, the company is keeping close communication with National Medical Products Administration Drug Evaluation Center, and actively striving for the best strategy to promote the clinical research on protective efficacy.

　　At the end of August 2024, it was announced that the company’s nine-valent HPV vaccine marketing license application was accepted. After the application for registration of the nine-valent HPV vaccine is accepted, it still needs to go through comprehensive evaluation, on-site verification and other procedures, which will not have a significant impact on the company’s financial situation and operating performance in the short term. After being approved for listing, it will be conducive to the promotion and use of the company’s HPV vaccine, enrich the company’s product line, further enhance the company’s core competitiveness and lay a solid foundation for the company’s sustained and steady development.

　　Many domestic vaccine companies are also competing for the HPV vaccine market for male indications. In November 2024, it was revealed that the nine-valent HPV vaccine for male population was approved for clinical trials. In addition, on February 12, 2025,Ruike biologyIt was disclosed that the application for clinical trial of the new adjuvant recombinant nine-valent HPV vaccine developed by the company for male population was accepted in National Medical Products Administration.

　　It is estimated that its nine-valent HPV vaccine (female indication) will be submitted in China and Indonesia respectively in 2025.License application (BLA), nine-valent HPV vaccine (male indication) is expected to be submitted to BLA in 2027.

　　open-sourceIt is predicted that with the successful completion of the third phase clinical trial of HPV vaccine and the release of its production capacity, its indications will be extended to the male population, and the vaccination awareness of the target population will continue to increase, and the market scale of HPV vaccine in China will continue to expand, which is expected to reach 62.54 billion yuan in 2031.

　　ASEAN countries are located at the intersection of land and sea in the Belt and Road Initiative, and are key areas for high-quality joint construction of the Belt and Road Initiative. In the past 10 years since the Belt and Road Initiative was put forward, from economic and trade exchanges to cultural exchanges, China-ASEAN Expo’s circle of friends has become larger and larger, and its outward attraction has become stronger and stronger.

　　— — — — — — — — — —

　　The 20th China-ASEAN Expo came to an end not long ago, but the vision of China and ASEAN countries meeting challenges together and building a closer China-ASEAN destiny community is inspiring people to move forward.

　　"This year, the Chairman of the Supreme Leader proposed to build a closer China-ASEAN destiny community and jointly build ‘ Belt and Road ’ The 10th anniversary of the initiative is also the 20th anniversary of the founding of China-ASEAN Expo and China-ASEAN Business and Investment Summit (hereinafter referred to as "China-ASEAN Expo" and "Summit" respectively). China — Wei Zhaohui, Secretary-General of the ASEAN Expo Secretariat, said that since China-ASEAN Expo and the Summit were held for 20 years, the bilateral trade volume between China and ASEAN has grown at an average annual rate of more than 13%, which has promoted the two sides to become each other’s largest trading partners and the most active partners in mutual investment, and helped to build a new pattern of China-ASEAN opening up at a higher level.

　　According to Xu Ningning, executive director of the China-ASEAN Business Council, ASEAN countries are located in the land-sea intersection of the "Belt and Road" and are key areas for building the "Belt and Road" with high quality. In the 10 years since the "Belt and Road Initiative" was put forward, China-ASEAN Expo has closely followed China — The needs of the times of ASEAN cooperation, constantly expand the functions of the platform, and promote the implementation of China — A series of consensus documents, joint statements and action plans reached by ASEAN have deepened China’s trade, investment, interconnection and regional cooperation with ASEAN countries, which is also the way to China-ASEAN Expo’s enduring success.

　　Inter-regional complementary resources promote active investment and trade.

　　The theme of the 20th China-ASEAN Expo is "Building a Home with Harmony, Destiny and Common Future — — Push ‘ Belt and Road ’ High-quality development and building an economic growth center. " At the meeting, many exhibitors expressed that they felt the dividends brought by the complementary market resources and factor flow between China and ASEAN. Zhu Qiugen, from Xishuangbanna, Yunnan, talks about tea at the exhibition during the day and packs tea for customers from all over the world in the hotel at night.

　　This year is his second time in China-ASEAN Expo, and he found that many tea lovers used to look at the price but now at the quality. "More and more customers have found me for the fragrance of tea, and people who understand the good products have found it. This change is more gratifying than how much tea I have sold."

　　Zhu Qiugen deals in ancient tea from Laos. The local tea garden employs local people to pick fresh tea and process it into "wool", and then it is transported to Xishuangbanna via China-Laos Railway for further processing to make a series of products such as tea cakes and tea bricks. Zhu Qiugen also founded the brand of "Laos Ancient Rhyme Tea Industry".

　　In recent years, thanks to the convenience of transportation and policies, Zhu Qiugen went deep into the country of origin and built a relatively complete industrial chain from picking, research and development, production and sales. "Let customers drink a cup of ancient tree tea that really comes from the mountains, without middlemen." In this way, the quality and cost have been well controlled.

　　The tea consumption market in China is huge, and the demand for high-quality tea has become a trend. Zhu Qiugen thinks that tea is a gentle lifestyle and a product that pursues quality of life. However, the domestic resources for picking ancient tree tea are limited, and some merchants have false propaganda and shoddy to some extent, which makes many consumers hesitate to buy.

　　In 2015, Zhu Qiugen just arrived in Laos, and he was doing hotel business at that time, but soon the local ancient tree tea fragrance caught his attention. In Laos, the unique and closed natural environment creates the good quality of Laos ancient tree tea, but these teas are mostly sold as agricultural products. "Laos has raw materials, and China has a market, so the connection naturally arises." Zhu Qiugen said.

　　With the opening of China-Laos Railway, Zhu Qiugen’s tea business has more convenient transportation conditions. If the tea is to be sold to Nanning market, Zhu Qiugen will choose to go by sea through Vietnam, which is "more cost-effective".

　　Guangxi is the only land-sea connecting region between China and ASEAN. The coastal, border and riverside areas of China-ASEAN Industrial Cooperation Zone are the frontier and window of Guangxi’s opening to the outside world. Relying on the existing parks in Nanning, Beihai, Fangchenggang, Qinzhou, Yulin, Baise and Chongzuo, Guangxi has integrated the construction of China-ASEAN Industrial Cooperation Zone, creating a development pattern of "one city, one area, one park". At present, many areas in the cooperation zone have achieved seamless traffic connection with ASEAN countries. For example, Chongzuo area is 180 kilometers away from Hanoi and Nanning, the capital of Vietnam, and there are four national first-class ports around it, which is the most convenient land international passage from China to Indo-China Peninsula.

　　"In July this year, Liuzhou Economic and Trade Delegation and 32 key enterprises went to Southeast Asia to carry out economic and trade exchange activities." Yao Fang, deputy director of the Management Committee of Liuzhou Economic and Technological Development Zone, said that the well-known domestic new energy automobile brands with factories in Liuzhou have actively gone abroad, and now they have sales markets in 72 countries and regions around the world.

　　The vigorous market demand drives the pace of transportation infrastructure construction. Sima Zhe, senior economist of the Asian Infrastructure Investment Bank and head of the ecosystem of the Ministry of Economic Affairs, said that in 2021, the AIIB provided 300 million US dollars to support the improvement project of border connectivity in Chongzuo, Guangxi, which improved the efficiency of cross-border connectivity around Shuolong Port and strengthened the economic and trade activities between China and Viet Nam.

　　In terms of commodity trading, the exchanges between Guangxi and ASEAN have become increasingly close. Guangxi is rich in commodity resources, with the output of white sugar, wood and raw silk ranking first in the country, and the output of alumina, pigs, pulp, Chinese herbal medicines and non-ferrous metals ranking first in the country. At the same time, Guangxi is also an important import port for ASEAN-specific commodities such as wood, non-ferrous metals, oil and gas, coal and fruits.

　　Li Kaizhou, deputy director of the local financial supervision bureau of Guangxi Zhuang Autonomous Region, said that in recent years, Guangxi has seized green opportunities, deepened cooperation with ASEAN, built a pilot free trade zone with high quality, and actively created a convenient place for domestic and international dual-cycle markets. The construction of new land and sea channels in the west has been accelerating. From January to July this year, Guangxi’s import and export to ASEAN was 188.08 billion yuan, a year-on-year increase of 71.6%.

　　Adhere to joint business and win-win sharing.

　　Wei Zhaohui, Secretary-General of China-ASEAN Expo Secretariat, said that since the China-ASEAN Expo and China-ASEAN Investment Summit were held 20 years ago, 196 Chinese and foreign leaders, more than 4,100 ministerial-level VIPs and heads of international organizations attended, which was accompanied by friendly relations between China and ASEAN and grew together with the construction of China-ASEAN Free Trade Area.

　　"China-ASEAN Expo has been successfully held for 20 years in a row, thanks to the unique exhibition mode. This is the successful password for China-ASEAN Expo to do something new and better." Wei Zhaohui introduced.

　　Adhere to business cooperation and win-win sharing, adhere to the principle of not making profits for ASEAN countries, respect ASEAN’s opinions on major issues, and give priority to meeting ASEAN’s needs in terms of booth arrangement. In this China-ASEAN Expo, the scale and proportion of ASEAN exhibitions remain the largest in China International Exhibition, and seven countries including Indonesia, Malaysia and Viet Nam have resumed their pavilions and restored ASEAN’s "Charming City" exhibition area.

　　Wei Zhaohui introduced that in all aspects of exhibition preparation, we should respect the ASEAN way, take care of ASEAN wishes, and always adhere to the value concept of "10+1>11". The ministers of economy and trade of China and 10 ASEAN governments and the ASEAN Secretary-General will serve as co-directors of the organizing committee, the directors of departments in charge of various countries will serve as deputy secretaries-general, and the directors will serve as liaison officers. Major issues will be discussed by the organizing committee meetings and senior officials meetings.

　　"International Friendship City Entering Dongbo" is also a highlight of the exhibition in recent years. According to the data of Foreign Affairs Office of Guangxi Zhuang Autonomous Region, at present, Guangxi has concluded 128 pairs of international sister cities with 39 countries, ranking fourth in the country. During this visit to China-ASEAN Expo, more than 30 sister cities from nearly 20 countries participated in the exhibition with their own special products.

　　"Before, our market was mainly concentrated in Jiangsu, Zhejiang and Shanghai. I never thought that the products could radiate to the inland of China and even ASEAN countries." Hong Yongwang, representing Zaragoza, Spain, said that Zaragoza and Yulin, Guangxi Zhuang Autonomous Region are international sister cities. Entrusted by the Zaragoza municipal government, Hong Yongwang brought more than 160 products including red wine, ham and olive oil to the site in China-ASEAN Expo.

　　Last year, the double-deck sinking square of Nahong Interchange Station of Nanning Metro, designed and built jointly by Nanning and Crema, Italy — — Friendship City Metro Plaza was officially completed, becoming the first subway station space in China that was fully decorated and designed by International Friendship City. At this year’s China-ASEAN Expo, exhibitor Zhang Xiaowei brought a painting entitled "Table Culture" to the scene to explain the Italian wine culture to the audience, and the author of this painting, Marilisa Leon, is the designer of the subway station space. Stephania Bonaldi, mayor of Crema, Italy, commented: "The design of the square is closely related to the theme of the Silk Road, which has brought the cultural ties between China and Italy closer and the two countries and peoples closer."

　　Institutional opening stimulates new kinetic energy of cooperation

　　From economic and trade exchanges to cultural exchanges, China-ASEAN Expo’s circle of friends is getting bigger and bigger, and its outward attraction is getting stronger and stronger. In the process of cooperation between China and ASEAN countries, many institutional and mechanistic modes of cooperation and dialogue have gradually taken shape.

　　During this year’s China-ASEAN Expo, a side event on the theme of "Institutional Opening: A New Pattern of Regional Economic Development" was held for the first time, and the "ASEAN National Standardization Cooperation and Exchange Center" was officially unveiled. The ASEAN cross-border e-commerce digital intelligence service platform and the e-commerce exchange center of the digital economy industrial park were announced to be open.

　　According to customs statistics, from January to August this year, the total import and export value of China to countries that jointly built the Belt and Road Initiative reached 12.62 trillion yuan, up 3.6% year-on-year, of which food trade reached 553.82 billion yuan, up 10.4% compared with the same period of last year and 162% compared with the same period of 2013. On the eve of the opening of China-ASEAN Expo, the Nanning Declaration on Customs Food Safety Cooperation on the Belt and Road was issued, and all parties signed the articles of association of the cooperation mechanism.

　　The perfection of the mechanism and articles of association aims at more convenient, long-term and stable factor flow. It is the consensus of many enterprises that "there is vitality when there is mobility, and there is market when there is mobility".

　　Last year, Guangxi Xinzhong Industrial Investment Co., Ltd. cooperated with the secretariat of China-ASEAN Expo to build a China-ASEAN special commodity gathering center. He Yan, the company’s deputy general manager, hopes that after participating in China-ASEAN Expo, economic and trade activities will continue for a long time through 17 offline pavilions and online platforms, and continuous economic and trade exchanges will take place with ASEAN countries in 365 days.

　　The international situation is complex and changeable, but the potential of the ASEAN market is constantly being released. "The number of ASEAN regional offices has grown particularly fast, exceeding our growth rate in China." Through this detail, Bo Yu, managing partner of PricewaterhouseCoopers Consulting (Shenzhen) Co., Ltd., found that the ASEAN market is being regarded as a growth point in the future, both in China and the world.

　　Bo Yu further analyzed that people value the population and future growth of ASEAN, and the population structure is relatively young. He believed that Guangxi should make good use of the role of "bridgehead".

　　As an Indonesian enterprise, Jinguang Group has been rooted in China for more than 30 years. Zhai Jingli, vice president of Jinguang Paper (China) Investment Co., Ltd., a subsidiary of Jinguang Group, believes that enterprises can make use of the cumulative rule of regional origin of RCEP and the advantage of the shortest and most convenient industrial supporting distance between Guangxi and ASEAN to expand the ASEAN market and play a good "ASEAN brand".

　　At present, some ASEAN countries have many environmental problems, such as soil degradation, water shortage and air pollution, which have affected local agricultural production and tourism and damaged local economic development to some extent. With the increasing demand for environmental protection in ASEAN countries, China’s environmental protection industry has gradually entered the ASEAN market. Hong Tao, director and professor of business economics research at Beijing Technology and Business University, pointed out in the China-ASEAN Forum on Innovation and Development of Commodity Trading that the effective implementation of RCEP has provided new impetus and cooperation foundation for promoting green recovery of regional economy, low-carbon development and global economic recovery, and reduced the cost of environmental protection industry in China.

　　In the past 20 years, the cooperation between China and ASEAN in the field of energy and electricity has been equally fruitful. By the end of August this year, China Southern Power Grid had been connected with the power grids of ASEAN countries through more than 10 circuits of 110 kV and above, achieving a total cross-border two-way power trade of nearly 70 billion kWh, of which clean energy accounted for over 90%. Hu Tianxiang of China-ASEAN Expo and china huadian Guangxi Company introduced that china huadian has invested in 9 projects under construction in ASEAN, with an installed capacity of 4.66 million kilowatts. In Cambodia, china huadian is the largest foreign power generation operator in Cambodia with an installed capacity of 1.038 million kilowatts under construction.

　　RCEP has entered a new stage of full entry into force and implementation, constantly releasing the strategic potential of economy and trade. Zhou Shi, a researcher and deputy director of the Research Office of the Market and Price Research Institute of the National Development and Reform Commission, believes that the import and export of Hunan and ASEAN countries in China increased by more than 70% in the year when RCEP was implemented, and the import and export of Guangxi to ASEAN countries also increased by 71.6% from January to July this year.

　　In the face of the current complicated and changeable international situation, many exhibitors realized that China and ASEAN are opportunities for mutual development and have great potential for cooperation. China was the first big country to sign and join the Treaty of Amity and Cooperation in Southeast Asia. In 2021, China and ASEAN upgraded their bilateral relations to a comprehensive strategic partnership.

　　Jiangsu Furen Group’s booth area in the 20th China-ASEAN Expo was not large, but the personnel in charge of market, operation and technology all came to the scene in order to better understand the ASEAN market and enterprises. In 2014, Jiangsu Furen Group held Jiangsu Xuzhou Forging Machine Group Co., Ltd., and two years later, it successfully acquired German EBU Forming Technology Co., Ltd. "This also marks that China Press has begun to rank among the world’s advanced manufacturing." Li Wei, deputy general manager of Xuforging Group, said that due to the rapid development of Thailand’s automobile industry in recent years, many internationally renowned automobile companies have invested and built factories in Thailand, and the export of intelligent forging equipment of Xuforging Group to Thailand has also increased by 20%-30%.

　　"The ASEAN market is becoming a new strategic growth point, especially in terms of labor structure, operating costs and market potential. The implementation of RCEP has also provided us with a stable and efficient supply chain network." Li Wei is full of expectations for the development of enterprises in the ASEAN market and the prospect of international cooperation. "We will also continue to enhance the technological breakthrough capability of intelligent manufacturing and better go abroad." (Zhongqing Daily Zhongqing Net Trainee Reporter Wang Junli Reporter Xie Yang Intern Zheng Quan)

With the popularization of HPV vaccine knowledge, many people want to be vaccinated with HPV vaccine. But how much do you know about HPV vaccine? What is the difference in the applicable population of HPV vaccines with different "prices"? In this regard, Chen Shouzhen, deputy director of the Obstetrics and Gynecology Hospital affiliated to Fudan University, summed up ten common questions and answered them to the majority of netizens.

What is HPV virus?

Human papillomavirus (HPV) is a small double-stranded DNA virus, so it is called human papillomavirus because it only infects humans. There are more than 200 subtypes of HPV, which can be divided into high-risk type and low-risk type according to whether they are carcinogenic or not.

Low-risk type usually infects the skin and causes warts, commonly known as boils. Most of them can naturally subside in 3-5 years, and some may need laser, freezing and other methods to remove them.

There are about 15 HPV subtypes (HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73 and 82) that can cause malignant tumors such as cervical cancer, vaginal cancer and oropharyngeal cancer, so they are called high-risk HPV. Among them, HPV16/18 has the highest risk of cancer. About 70% of cervical cancer in the world is caused by high-risk HPV16 and 18, and 20% is caused by HPV31, 33, 45, 52 and 58. HPV16 types 16 and 18 are also associated with oropharyngeal cancer, vulvar cancer, vaginal cancer, penile cancer and anal cancer.

Will HPV infection definitely lead to cancer?

Persistent infection of high-risk HPV will lead to cancer. More than 90% of HPV infections usually subside naturally within 2 years. If carcinogenic HPV infection lasts for more than 1 year, the possibility of precancerous or cancerous lesions will increase, but not all persistent infections will progress. Only less than 1% of infections will develop into cancer after 5 to 10 years of precancerous lesions. Therefore, even if there is HPV infection, it will not necessarily become cancer, but we should pay attention to the corresponding screening.

At present, there is no specific drug to treat HPV. Through regular screening, we can observe the situation of HPV infection, so that we can treat it at an appropriate time and reduce the risk of cancer.

Personal life is very healthy, how can you be infected with HPV?

HPV virus spreads in various ways.

It can be widely spread among people through skin contact, and more than 80% of women have been infected with HPV at least once in their lives. Sexual life is the main reason why HPV spreads around the anus and genitals. Sticking to the correct use of condoms can reduce the risk of HPV infection.

Generally speaking, there are many ways of HPV infection. At present, there is no good way to prevent HPV infection, but healthy living habits, such as quitting smoking and drinking, and wiping separately after going to the toilet may reduce the probability of HPV infection. Even if you are infected with HPV, you don’t have to be nervous, because most HPV infections can be monitored regularly after infection, and generally will naturally fade away soon.

How to prevent HPV transmission?

Vaccination with HPV vaccine can safely prevent cancer caused by persistent HPV infection.

Vaccination with tetravalent or nonavalent HPV vaccine can also prevent condyloma acuminatum, which is a benign disease, but the treatment failure rate is relatively high, affecting physical and mental health. Therefore, for the majority of women, it is very necessary to vaccinate HPV vaccine.

How to choose HPV vaccine?

At present, three different vaccines have been developed, which are divided into bivalent, tetravalent and nonavalent vaccines according to the number of HPV subtypes they target. Simply put, bivalent HPV vaccine is aimed at HPV types 16 and 18; The tetravalent HPV vaccine is aimed at HPV6, 11, 16 and 18; The nine-valent HPV vaccine not only targets the same HPV subtype as the four-valent vaccine, but also targets types 31, 33, 45, 52 and 58. At present, HPV vaccines are all preventive vaccines, aiming at preventing initial HPV infection and subsequent HPV-related diseases.

At present, many hospitals, from community medical service centers to tertiary hospitals, have HPV vaccines, and these HPV vaccines can be safely vaccinated. Because of limited resources, the queue time of nine-valent vaccine will be longer. If resources and funds are not a problem, it is recommended to vaccinate the nine-valent HPV vaccine. If there is no nine-valent HPV vaccine, tetravalent HPV vaccine and bivalent HPV vaccine are also good choices, because both vaccines cover the most dangerous types 16 and 18. Generally speaking, you should try to use the same vaccine preparation to complete vaccination. However, if you don’t know the original HPV vaccine dosage form, you can also use another HPV vaccine preparation to complete the subsequent vaccination.

At what age is it appropriate to get HPV vaccine?

At present, the recommended age of HPV vaccination in China is 9-45 years old. Most countries in the world recommend routine HPV vaccination at the age of 11-12, and some suggest starting from the age of 9. For teenagers and adults aged 13-26, replanting is also recommended if they have not been vaccinated with HPV vaccine or have not completed a series of vaccines.

Why don’t foreign countries recommend routine replanting for adults over 27 years old? This is because with the increase of age, the possibility of infection with subtypes covered by HPV vaccine is gradually increasing. For older people, the benefit and cost performance of HPV vaccination are low. However, research shows that there are two peaks of high-risk infection among women in China: 17-24 years old and 40-44 years old, and single HPV infection is the main infection. Considering the characteristics of female infection and the low coverage rate of cervical cancer screening, experts suggest that women aged 9-26 should be vaccinated with HPV, and women aged 27-45 should be vaccinated when conditions permit. Women over the age of 45 don’t have to worry. At this stage, the HPV vaccine is low in cost performance, and the standardized HPV screening is enough to prevent cancer.

In the recommended age range, the best time for HPV vaccination is before the first sexual intercourse, because HPV vaccine immunization is the most effective for individuals who are not infected with HPV. That is to say, the younger you are when you are vaccinated with HPV, the more the incidence of cervical cancer decreases.

Are there any side effects of vaccination?

Vaccination of HPV vaccine, like other vaccines, may have pain, swelling and erythema at the inoculation site. A few people may have syncope or dizziness, and there are some rare other side effects, which may be related to the adjuvant in the vaccine, so you can rest assured to vaccinate. In addition, HPV vaccine can be safely inoculated in different parts with other vaccines at the same time. At present, there is evidence that inoculation of tetanus, acellular pertussis, diphtheria and inactivated polio vaccine at the same time with HPV vaccine does not damage the immune effect of the body against HPV vaccine or other vaccines at the same time.

Because there is no relevant evidence, it is generally not recommended to vaccinate HPV during pregnancy. However, with the increase of the number of people vaccinated, more and more data about unintentional vaccination after pregnancy show that vaccination during pregnancy has no effect on the safety of mother and child. Nevertheless, the remaining vaccination should be postponed, and it is best for vaccinated women to get pregnant two months after the vaccination is completed. Vaccine does not affect the safety of breastfeeding, but at present, such data are limited, so it is necessary to carefully consider HPV vaccination for lactating women.

I have been infected with HPV before, can I still be vaccinated?

There is no need to evaluate whether you have been infected with HPV before vaccination. A history of abnormal cervical cancer screening, genital warts and HPV infection is not a taboo for HPV immunization. Because these conditions all suggest that HPV was infected in the past, but it is not necessarily HPV subtype infection covered by HPV vaccine. For people who have a history of HPV infection but are still within the recommended age range, vaccination is still recommended because it still has a protective effect on the uninfected vaccine strain HPV virus. However, for people who have been infected with the subtype covered by HPV vaccine, the benefits of immunization are small.

What if we miss the seeds? I have been vaccinated with bivalent or tetravalent HPV vaccine before. Do I need to replant with nine-valent HPV vaccine?

Missing seeds means that immunization is not carried out according to the schedule. At present, the evidence shows that no matter how long the series vaccination is interrupted, it can continue to vaccinate without restarting the series vaccination.

Now it is found that HPV vaccine has a long-lasting protective effect against HPV-related diseases, and there is no need for multiple cropping. For women who have already completed bivalent or tetravalent HPV vaccination, the benefit of using nine-valent vaccine for multiple inoculation may not be obvious, so it is not recommended.

After vaccination with HPV vaccine, can I avoid regular screening?

At present, HPV vaccine can only prevent infection. After vaccination, existing HPV infection, genital warts or precancerous lesions cannot be eliminated, and the vaccine can only prevent cervical cancer caused by seven subtypes at most. After injection of HPV vaccine, other subtypes of HPV may still be infected, which may lead to cancer. Therefore, cervical cancer screening is still needed after HPV vaccination.

General rule

　　On April 25th, 2024, the 18th auto china will officially open in Shunyi Pavilion of China International Exhibition Center. At that time, BYD will land at booth W106 in Hall W1, in which the lineup of Ocean Network will be exposed, and a number of brand-new models, such as Seal 06DM-i, Sea Lion 07EV and concept car OCEAN-M, will be unveiled hand in hand.

　　The new medium-sized car, Seal 06DM-i will be equipped with the latest technology.

　　Seal 06DM-i is a brand-new medium-sized car under BYD Ocean Network, which is positioned between destroyer 05 and seal DM-i.. It is reported that Seal 06DM-i will be equipped with BYD’s latest technology, and the chassis quality and safety control will be greatly improved. The sword refers to the joint venture fuel medium-sized car market.

　　Seal 06DM-i continues the marine aesthetic design, with a body size of 4830*1875*1495mm and a wheelbase of 2790mm, reaching the level of mainstream medium-sized cars; In terms of power, Seal 06DM-i will adopt a 1.5L engine and provide 120kW and 160kW motors.

　　Ocean Net’s first medium-sized pure electric SUV, Sea Lion 07EV is equipped with "Eye of God" high-order intelligent driving.

　　BYD Haishi 07EV is positioned as a "medium-sized urban smart electric SUV", which is based on BYD’s latest pure electric platform technology. It is the first medium-sized pure electric SUV of Ocean Net and the first model of Ocean Net’s brand-new Haishi IP. Sea lion 07EV combines the latest pure electric platform technology and forward-looking aesthetic thought, and integrates face value, safety, comfort, intelligence, performance and efficiency. At the same time, based on the advanced electronic and electrical architecture, Sea Lion 07EV adopts the advanced version of intelligent cockpit -DiLink 100 and the advanced intelligent driving assistance system of Eye of God -DiPilot 100, which brings users a full-scale intelligent travel experience.

　　BYD Sea Lion 07EV will further expand the product matrix of Ocean Net, strengthen the layout of Ocean Net in the field of high-value products, and meet the yearning and pursuit of more young consumers for high-quality driving life.

　　The industry’s first hatchback rear-drive pure electric steel gun, the world’s first show of OCEAN-M concept car.

　　The brand-new concept car OCEAN-M will also make its world debut. As the first rear-drive pure electric steel gun model in the industry, it has a brand-new advanced aesthetic design and is equipped with a brand-new pure electric platform. It is another masterpiece of BYD Ocean, which focuses on the promotion and popularization of new energy vehicles, and deserves continuous attention.

　　Summary:

　　BYD Ocean Network brought a number of brand-new models to the Beijing Auto Show. Seal 06DM-i and Sea Lion 07EV will form a brand-new "Gemini", which will empower new experiences with the latest technology and become the most anticipated new energy vehicle at this Beijing Auto Show. OCEAN-M concept car will show the future charm of Ocean Network with the posture of seeing the future now. On April 25th, auto china BYD booth, let’s pay attention together!