CCTV News:Neihuang County, Anyang City, Henan Province, is a traditional agricultural county in the northern plain of Henan Province. Since 2009, Neihuang County has invested in a large-scale ceramic industry and introduced a number of ceramic enterprises, which has brought about a ceramic industrial park with an annual output value of more than 10 billion yuan. Business is booming and the industry is booming, which is a good thing, but the local people have been calling the media to complain about the pollution caused by the ceramic industrial park in the village recently, and the people are complaining.

　　UAV shoots ceramic industrial park at an altitude of 200 meters.

　　On March 12, 2018, the reporter came to Neihuang County, Henan Province. In order to verify whether there was any pollution problem in the local ceramic industrial park, the reporter used a drone to shoot the ceramic industrial park in Neihuang County at an altitude of 200 meters. As far as the eye can see, there are many factories and bare white powder piled up everywhere. Neihuang Ceramic Industrial Park is the largest ceramic production base and product distribution center in the Central Plains. The industrial park is divided into two parts, one is the production area and the other is the sales area. Although the production enterprises have not started, the business of large and small ceramic tile sales stores is still very prosperous. Sales staff told us that most of the tiles sold by these stores came from the production enterprises in the park. During the conversation, the reporter hoped to know whether ceramic tile production would pollute the environment. Unexpectedly, the salesperson answered directly.

　　Sales staff of ceramic industrial park in Neihuang County, Henan Province: "The pollution is not small, because there is no way to eat groundwater now. When the country stops production, our side stops during the day and produces at night."

　　The surrounding area of the ceramic park looks like a fire scene from afar.

　　In order to find out the truth, the reporter conducted an investigation in and around Neihuang County Ceramic Industrial Park for several days. Finally, on the evening of March 20th, the reporter smelled a strong and pungent smell around the ceramic park, which was suffocating. The company named "Langer Ceramics Co., Ltd." emitted huge smoke. Even in the night, the smoke was extremely amazing, thick and thick, looking from a distance, like a fire scene, and the air was filled with the choking smell of kerosene.

　　Sewage forms a colorful oil stain on the river.

　　The Xiaohe River is the only river in Neihuang County. On the morning of March 21st, the reporter noticed that the "white" sewage was continuously discharged into the river through a drain. These discharged "white water" have foam on the surface and an unpleasant smell. These are the two outlets under the Xiaohe Bridge, and the sewage has formed a colorful oil stain on the river. We walked along the section of the Nitrate River passing through the ceramic park and found that there were seven similar outlets in total. Some villagers who work in the ceramic factory told reporters that the wastewater generated in the ceramic production process will first be discharged into the sewage pool of the factory, and then slowly seep into the ground. Every rainy day, we will "take the opportunity" to discharge it into the nitrate river next to the ceramic park along the rainwater pipeline.

　　Pollution causes crops to fail to collect groundwater.

　　What impact does the pollution caused by ceramic enterprises have on local people? The reporter saw in an interview with Xiaotun Village, the nearest village to the west side of the ceramic industrial park, that the villagers told us about their experiences one after another. Near the ceramic industrial park, the wheat began to turn yellow.

　　Local villagers: "The wheat is too small to be obvious, the pepper is obvious, the fruit is on top, and the wheat is wrapped in a shell. It was obvious as soon as the ceramic factory started. The smoke it emits is glazed in the factory, and the corn is covered with white powder, which is the same as frost. It doesn’t bear ears, and red peppers don’t bear peppers. "

　　The crops in the fields near the ceramic factory are almost never harvested.

　　The villagers told reporters that in recent years, almost all the crops in the fields near the ceramic factory have been harvested every autumn. In the eyes of the villagers, the "culprit" that caused the grain harvest was the "smoke" coming out of the chimney of the ceramic factory. Besides air pollution, the local people are more afraid of the water discharged from the ceramic factory. In the village of Dadikou, which is just across the river from the ceramic park. The groundwater in the village has been polluted, and the water quality of the well water, which was originally clear and bright, has become worse and worse, and it can only be used for washing clothes or feeding animals. As a last resort, the villagers can only go far and near, and dig wells from other villages dozens of miles away. In this villager’s home, he specially pumped a bucket of water from his well more than 30 meters deep.

　　The groundwater is dirty, and there are oily floating objects on the water surface.

　　In order to prove to the reporter that the pollution he suffered was absolutely true, the villager deliberately burned a pot of hot water. Just after heating, the reporter found that a layer of floating objects like oil stains appeared on the water surface, and a lot of scale appeared at the bottom. During the investigation, the reporter visited several villages around the ceramic industrial park. The dirty groundwater can be seen everywhere, and the groundwater in Xizhangbao Village, located on the east side of the ceramic industrial park, has also been seriously polluted. The staff of Guardian Ceramics Co., Ltd. admitted that there was water pollution in the park.

　　Ceramic factories issue "pollution fees" according to the distance.

　　In addition, during the interview, the villagers all mentioned a "pollution fee" issued by the ceramic factory. They told reporters that according to the distance between each field and the ceramic factory, the ceramic factory subsidizes the expenses ranging from 20 yuan to 100 yuan per mu.

　　Reducing cost to avoid "coal to gas" sewage treatment is not up to standard

　　In fact, the environmental protection department has clearly stipulated the emission limits of pollutants such as sulfur dioxide, nitrogen oxides and particulate matter in ceramic industrial enterprises. Then, have the production enterprises in Neihuang County Ceramic Industrial Park strictly implemented the emission standards of pollutants in ceramic industry and installed environmental protection facilities such as desulfurization, denitrification and dust removal?

　　salesman: "One of our factories, the smallest one, has to use 300 to 400 tons of coal. If it is a big factory, it has to reach the concept of 500 to 800 tons. Air pollution, smog and desulfurization will not work, and it will also exceed the standard. You can desulfurize during the day, and I’m still discharging at night. This thing, there is no way, if you want to reduce costs, you can only do this. "

　　Cost-reducing enterprises steal sewage at night

　　The salesperson who claimed to be Neihuang Jiade Ceramics Co., Ltd. told the reporter that in order to reduce costs, enterprises can only use night smuggling. However, if clean energy natural gas is used, it is relatively easier to meet the requirements in the standard, but it will inevitably lead to an increase in the cost of tiles. According to insiders’ calculation, if "changing coal into gas" is implemented in Neihuang production area, the production cost of ceramic enterprises will increase by 18%, and the cost of a tile will increase by 50 cents. For cost reasons, up to now, there are still many ceramic enterprises in Neihuang Ceramic Park that have not changed from coal to gas.

　　Besides the potential waste gas pollution, how do the ceramic factories in Neihuang Ceramic Industrial Park treat their production wastewater? This is a report in Henan Daily in 2016, which clearly reads: "The sewage treatment project in the south of Neihuang City, with an investment of 28 million yuan, can treat 5,000 tons of sewage every day, which can basically meet the sewage treatment needs of ceramic parks. While promoting the transformation and upgrading of the ceramic industry, the project has also achieved both economic and environmental benefits." Two years have passed, has this sewage treatment project with an investment of 28 million yuan been completed, and is it treating industrial wastewater generated by ceramic factories? With all kinds of questions, the reporter came to Bishuiyuan Sewage Treatment Plant in Neihuang Ceramic Park.

　　The staff of several sewage treatment plants told reporters that this sewage treatment plant was put into operation in the second half of 2017. Due to the limitations of the process, it was only responsible for treating the domestic sewage in the ceramic factory. As for where the industrial wastewater generated by the ceramic factory went, they did not know.

　　Functional departments shirk environmental pollution and lack supervision

　　The reporter learned in the Neihuang County Water Affairs Bureau that in the Neihuang County Ceramic Industrial Park, the drain that the reporter saw was not built by government departments, but was built privately. The staff of the Neihuang County Water Affairs Bureau also suggested that the reporter report to the Environmental Protection Office of the Ceramic Park. According to the address provided by the staff of the Water Affairs Bureau, the reporter found the "Zhongyuan Porcelain Capital Environmental Protection Institute".

　　As soon as I entered the door, the reporter thought I was in the wrong place, and the environmental inspection department was located in the marketing hall of the ceramic production enterprise. As an environmental volunteer, the reporter met the person in charge of "Zhongyuan Porcelain Capital Environmental Protection Institute". In the face of a reporter’s question, the person in charge of Zhongyuan Porcelain Capital Environmental Protection Institute told the reporter that the responsibility of Zhongyuan Porcelain Capital Environmental Protection Institute is to check the sewage discharge and air pollution of production enterprises, but when the reporter reported that the enterprise had secretly discharged sewage and secretly built sewage outlets to discharge industrial wastewater directly into the river as an environmental volunteer, the person in charge said that they were "unaware" of the number of sewage outlets under the Xiaohe Bridge and the pollution situation. Neihuang county monitors the groundwater around the ceramic park every year, and has never found any pollution problems. In the face of such an answer, the reporter suggested that it was less than one kilometer from the enterprise to the "Zhongyuan Porcelain Capital Environmental Protection Institute", hoping to take environmental inspectors to check it on the spot, but I didn’t expect it to be rejected by the staff of the Environmental Protection Institute.

　　During the interview, the villagers told reporters that since nearly 90% of the laborers around the ceramic factory are working in the factory, on the one hand, they are polluted hometown, and on the other hand, they are worried about the future, and more are helpless.

　　villager: "Ceramic factory has certain advantages and disadvantages. The advantage is that there is a place to work and earn money, so you don’t have to go out, especially for women. The downside is that the pollution is too strong. "

　　On the one hand, it is a polluted environment, and on the other hand, it is an important source of local tax revenue. Which is more important? This is indeed a multiple-choice question before the local people and the local government. However, a good ecological environment is the fundamental foundation for the sustainable development of people and society. I hope the local government can do this multiple-choice question well, and don’t destroy the homes of future generations for the sake of immediate achievements and immediate interests.

On August 3rd, Netease Cloud Music and Tik Tok officially announced a cooperation to jointly build a "music+short video" content ecosystem. The two sides will strengthen the support and promotion of musicians and music works, explore the diversity of music, help more outstanding musicians and works out of the circle, and effectively increase the income of musicians.

Netease Cloud Music and Tik Tok will explore musicians’ support, music announcement, music copyright, music IP and other aspects, focusing on issues that musicians care about, such as creation, exposure, income, and work management, and give full play to the superior resources of their online music platforms and short video platforms.

Video shooting/video editing: Liang Xuhao

Luo Zhengxiang, reporter Liang Yihao, photo

[Guangdong famous doctor who has been a doctor for 70 years]

Jinyang. com reporter Feng Xixi correspondent Yue Weixin Zhang Lanxi Zhang Lingling Yuting

Professor Luo Zhengxiang, 93, is a famous expert in cardiothoracic and vascular surgery in China. He used to be the president of Guangdong Provincial People’s Hospital and the director of Guangdong Institute of Cardiovascular Diseases. From a handsome young boy to a white-haired old man today, years have left traces, but he can never change the "passion" in his heart-"saving lives" is his lifelong pursuit.

Under his leadership, Guangdong took the lead in establishing the Institute of Cardiovascular Diseases in China, and its reputation is still far-reaching. This famous cardiovascular expert also won the honor of "Outstanding Contribution Award of China Cardiothoracic Surgery".

The "best student" was admitted to medical college.

Luo Zhengxiang, 93, has gray hair, but his figure is straight. He is still a handsome elder in a suit. His thinking is very clear. When he is free, he watches movies and listens to classical music. When he goes out, he takes a mobile phone and "scans the code to pay" like a young man. He is a "grandfather". This "post-90 s" grandfather has made outstanding contributions to the development of cardiovascular disease in China.

In 1947, Luo Zhengxiang did not study business or economics as expected by his father. "When I was a child, I loved reading history books and wanted to be a hero. At that time, the best students could be admitted to medical school, so I went after the hardest." With an indomitable spirit, he successfully passed the West China University of Medical Sciences.

In 1954, Luo Zhengxiang came to work in Guangdong Provincial People’s Hospital, and chose the most difficult and complicated major in the medical field at that time-cardiac surgery. Since then, he has embarked on a journey of "heart" for more than half a century.

Cardiac surgery was difficult to start in China at that time. But Luo Zhengxiang never gave up his research on heart disease-heart surgery is extremely demanding, starting with the most basic hemostasis practice. The great blood vessel was accidentally broken and the blood was shocking. Luo Zhengxiang looked at the shadowless lamp, pressed it, pressed it, pinched it, and stitched the wound with a big curved needle. He was calm and calm for a few times: OK. The valves are stitched one by one, and repeated actions are done over and over again, which is simple and boring. 1 hour, 2 hours … Some doctors have been standing on their legs and looking at them, but Luo Zhengxiang is staring, unhurried and meticulously crafted.

"I used to have surgery and the conditions were very bad. Eating a dollar at noon is simple; There is no air conditioning in the operating room. Everyone is sweating after the operation and can only drink more water after the operation. " Luo Zhengxiang said that although the conditions are difficult, everyone can work together with Qi Xin. "The director of the department takes the lead in suffering, and the doctors and nurses will follow suit. This is a kind of atmosphere and a kind of culture."

The first generation of artificial biological heart valve in China has been developed.

In 1974, after visiting Beijing, Shanghai and Guangzhou, Argentine cardiovascular experts decided to invite Guangdong experts to study cardiovascular technology in Argentina. On March 16th, 1974, a technical team organized by the Ministry of Health, mainly from Guangdong Provincial People’s Hospital (Xiang Xiangyao, Luo Zhengxiang, Chen Chuanrong, Wei Wanchang, Chen Zhiming, Wang Tailai and Jin Si Lan from the First Affiliated Hospital of Sun Yat-sen Medical College) went to Argentina for a one-year medical investigation. This year’s study was fruitful, and Luo Zhengxiang and his party brought back advanced valve technology. In 1977, Luo Zhengxiang and Cai Zengxin went to an Italian hospital in Argentina again to study heart valve technology. In 1975, the first domestic aortic valve replacement was successfully implemented, and the first domestic pediatric valve replacement was successfully implemented in the same year …

In the 1970s, rheumatic heart disease and rheumatic fever prevailed in southern China, but for these patients who need valve replacement, heart valves need to be imported, which is expensive and few people can afford it. Luo Zhengxiang and his colleagues are determined to make Chinese’s own heart valve. In 1976, Guangdong Institute of Cardiovascular Diseases set up a research room for artificial heart biological valves, and then cooperated with Australian medical expert Dr. Zhang Renqian to set up Pacific Biological Products Company in Huangpu District of Guangzhou with full reference to international standards to develop and produce artificial heart valves. In 1977, the first generation of artificial biological heart valve in China, Guangdong Type I, was developed and applied in clinic, taking the lead in the perioperative management of cardiac surgery and the application of intra-aortic balloon counterpulsation in critical heart surgery. In 1987, Guangdong II artificial heart biological valve was successfully developed, and in 1988, the artificial mechanical heart valve was successfully developed in cooperation with Australian experts and applied in clinic. Domestic valves greatly reduce the cost of patients’ surgery and shorten the gap between cardiothoracic surgery in China and advanced countries in the world.

3. Lead the Institute of Mind Research to break through difficulties and create brilliance.

In 1958, Guangdong Provincial Institute of Thoracic Diseases was established in Guangdong Provincial People’s Hospital. For various reasons, the development of the institute was quite tortuous. On August 7th, 1978, Guangdong Provincial Party Committee agreed to rename Guangdong Thoracic Disease Research Institute as "Guangdong Cardiovascular Disease Research Institute", and the Ministry of Health listed Guangdong Cardiovascular Disease Research Institute as one of the three key cardiovascular disease research institutes in China (Beijing, Shanghai and Guangdong).

In this way, the Guangdong Institute of Cardiovascular Diseases was established, but how to go next is a problem that Luo Zhengxiang has to face. Now, 93-year-old Luo Zhengxiang goes back to the Institute every day to see this old place where he has been "cultivating" for decades. Every time he walks past the entrance of Dongchuan Road, Guangzhou, he will think of the difficulties of that year: "The Institute had no funds at first, and we ran to the cement factory to find the cement. I wear leather shoes to the construction site every day to supervise the work. After that, I change my clothes and go back to the operating room for surgery. " In this way, with the concerted efforts of everyone’s Qi Xin, the Institute of Mind Research has grown up slowly.

Today, it has gone through 61 years. Over the past 61 years, the Institute has trained a large number of experts for the country, treated tens of thousands of patients and laid the foundation for the prevention of cardiovascular diseases. Created countless national firsts, first cases, and even world firsts.

Young doctors love to chat with Luo Zhengxiang, and he is also willing to communicate with young people. He said that he likes to chat with patients when he sees a doctor, and it is easier to build trust when he gets familiar with each other. "When you are a doctor, you must be dedicated to the patient and do everything for the patient; I have been a doctor for decades, and some patients have not been saved, but no one has ever made trouble, because they all know that I am saving with my heart. Whether the doctor is careful or not can be seen by patients and their families. "

[famous doctor said]

When you are a doctor, you should devote yourself to the patients.

When you are a doctor, you should be dedicated to the patient and do everything for the patient; I have been a doctor for decades, and some patients have not been saved, but no one has ever made trouble, because they all know that I am trying to save them.

Recently, we obtained the latest spy photos of the M8, which indicates that this new model is expected to meet the public at the end of this year.

As can be seen from the spy photos, this camouflage car is a 6-seat version, which is different from the previously guessed 5-seat version M9. Although the number of seats has changed, the overall shape and outline are highly similar to the current M9, including the body size, and there is no significant difference. The comparative analysis shows that the front face design of the new car is closer to the boundary M7, which is embodied in the straighter front cabin cover shape and the headlight edge shape similar to the boundary M7.

In addition, the vehicle in the spy photos adopts a short front suspension design, which is conducive to maximizing the utilization of internal space in a slightly reduced body size. In terms of details, the new car seems to have cancelled the roof rack and the roof lidar.

According to the spy photos that flowed out before, it is expected that the M8 will be equipped with taillights of the same style as the M9, and equipped with the same lamp programming function. The exposure of this information has undoubtedly increased the market’s expectation and curiosity about M8.

　　[Aika Auto Domestic New Car Original]

　　On September 17th, 2023, Geely Automobile officially announced the prices of two new models of the Star Yue L in Xi ‘an Black Light Factory, namely the Yun Qi version with a guide price of 157,700 yuan and the Skyline version with a guide price of 168,700 yuan. As new models, Yun Qi version and Skyline version have added exclusive design on the basis of Star Yue L, and are equipped with the latest vehicle system of Galaxy OS 2.0. While announcing the selling price, Geely Automobile also announced the car purchase courtesy including financial gift, rejuvenation gift, quality gift, maintenance gift and flow gift. At the same time, Geely Automobile also announced that it will push the Galaxy OS 2.0 car system for all old users OTA of Xingyue L for free.

　　The exclusive designs for these two models include the far-Dai matte gray car paint and the ink-splashing environment-friendly suede interior. Among them, the official guide price of Yuandai frosted gray car paint is 6,000 yuan, and the official guide price of splash-ink environment-friendly suede interior is 3,000 yuan, while the Sky Edition will come standard with splash-ink environment-friendly suede interior. The environment-friendly chamois interior is covered with a large area of environment-friendly chamois. The covering rate of the seat surface is 68.8%, the ceiling is 100%, and the door panel and instrument panel are all covered with chamois. Not only has the touch been improved, but the sense of advanced has also been filled. In addition, the Galaxy OS 2.0 car system has a brand-new UI design, which is more fashionable and beautiful. The voice wake-up speed reaches millisecond level, and the whole scene can be seen. At the same time, a custom desktop that is more in line with the operating habits of the mobile terminal is adopted to create a more intelligent and non-inductive interactive experience for users.

　　A quick look at the highlights of new cars

　　·　Newly added exclusive designs, including Yuan Dai matte gray car paint and splash-ink environment-friendly suede interior.

　　·　Equipped with the latest Galaxy OS 2.0 car system.

　　·　2.0T+8AT

　　New car introduction

　　In terms of appearance, Geely Xingyue L adopts the family-style design language of Geely Automobile 4.0 generation products, and continues to maintain the high value of atmospheric dynamics. In terms of details, the front face of Xingyue L adopts the iconic straight waterfall air intake grille, and the black middle net is decorated with chrome trim, which makes the front face look very delicate and dynamic. The headlight with full LED light source energy matrix is very sharp in shape, and the two-stage design is highly recognizable. A chrome-plated decorative strip is added to the front enclosure that runs through the design, which is perfectly integrated with the L-shaped chrome-plated decorative strips on both sides.

　　Viewed from the side, Xingyue L adopts a muscular line design, which, together with the burly body size, makes the side look very atmospheric. In terms of body size, the L length/width/height of Xingyue is 4770*1895*1689mm, and the wheelbase is 2845 mm.. The rear of the car continues the family’s atmospheric and steady design style. The biggest highlight is the adoption of the popular through taillights, and the interior adopts the "aurora dot matrix" design, which is full of scientific and technological sense.

　　As for the interior, Xingyue L has adopted a brand-new design concept of "Symphony of Time and Space", and all designs have demonstrated the people-oriented design idea. High-grade suede fabric is widely used in the interior, and the exquisite pearl stitching is used. With the special suede seat with the ultimate skin-friendly touch, the exquisite, elegant and unique car interior is created for the vehicle. In addition, three large 12.3-inch screens are also a highlight of the interior. The 12.3-inch central control screen uses Qualcomm Snapdragon 8155 chip, while the 12.3-inch screen in front of the driver integrates rich functions such as watching videos, listening to songs, games, Tik Tok and karaoke.

　　In the power part, the two new models are equipped with the high-power version of the Drive-E series 2.0TD engine, with a maximum power of 175kW(238 HP) and a peak torque of 350Nm. The transmission is equipped with the 8AT gearbox from Aisin.

　　Editor’s point of view: Up to today, the cumulative sales volume of China Star Series has exceeded 730,000 vehicles, among which the cumulative sales volume of Xingyue L has exceeded 300,000 vehicles, with an average monthly sales volume of over 10,000 vehicles. It is worth mentioning that in August, the sales volume was 17,169 vehicles, with the monthly sales exceeding 15,000 vehicles for three consecutive months. In the past five months, the sales volume of high-equipped 8AT products accounted for over 65%. The addition of the two new models not only brings a more exclusive design, but also brings a richer choice of models for consumers who are concerned about Xingyue L.

　　Wonderful content review:

　　The release of Geely Panda Knight is expected to be launched in early September.

　　Geely Panda mini "Asian Games Bear" has been listed for 29,900 times.

　　Geely Panda mini is officially listed at a price of 39,900 yuan.

In the retail circle, the membership system has been iterative, so we might as well look at the membership logic from Amazon, Nike, Sephora, Starbucks and Xiaomi.

This article comes from WeChat WeChat official account:Retail Watch (ID: On Retail), author: Wang Ziwei

For retailers, the membership system is basically unavoidable. Let’s take a look at what the most mainstream membership system in the e-commerce era is like.

From a global perspective, there are seven most common forms:

1. Integral-hierarchy system

2. Service subscription system

3. Entity subscription system

4. Charity system

5. Sharing cooperation system

6. Community system

7. TOKEN system

I. Integral-Hierarchy System

This is almost the simplest one. In short, every time you spend X yuan, you get Y points. The more you spend, the higher the score.The only variable seems to be that there may be reward points at different times and through different channels, such as 5 times points for in-store consumption during the celebration period and 10 times points for e-commerce consumption during the Black Five/double 11 period.

Let’s take a foreign example, that is, the clothing brand "North"（North Face）",its integral system is called" VIPeak ".

For consumers, understanding this system is also very simple, that is, for every dollar spent, they get 10 points-whether online or offline, if they spend at outlets, they get 5 points for every dollar.

These points can be used in future consumption. To this end, North Face allows users to manage their accounts, buy goods, see points and redeem rewards through the App.

This is the simplest point system, through which consumers are willing to continue to shop. North Face is a typical single-level membership system.

Based on this logic, there will be a multi-level membership system, generally and periodically.(e.g. 1 year)The consumption amount or points are positively related.The characteristic of hierarchical system is that the higher consumers spend, the more rewards they get.

This level itself is also a gamification system, which links consumption with "playing". In the United States, a classic case is the beauty brand e.l.f

Consumers with 0-100 points are at the first level, consumers with 101-400 points are at the second level, and those with 401 points or above are at the highest level-the more membership points, the more unique the rewards.The uniqueness of the highest level is an important factor that urges consumers to buy more goods.

From the point of view of points, the first-level consumers get 2 points for spending 1 dollar, the second-level consumers get 4 points for spending 1 dollar, and the third-level consumers get 6 points for spending 1 dollar, and consumers can get corresponding services by using points.

Similarly, Starbucks in the United States also has this hierarchical system, which is divided into green card levels.（Green Level）And gold card level（Gold Level）.

When the user has less than 299 stars, it is a green card level, and will enjoy the privileges of getting 2 stars for every $1 spent, birthday gifts, mobile payment, placing orders in advance, and free refills in the store; When the number of stars reaches 300 or above, the user will be upgraded to the gold card level. At this time, he will not only enjoy all the green card level permissions, but also double the star accumulation day every month, get a gold card membership card with his name printed on it, and exchange free food or coffee every 125 stars.

In addition to getting stars through consumption, there are also some activities in Starbucks APP, such as going to the store for consumption at a specific time, getting extra stars, and buying specific goods to get extra star rewards.

Second, the paid subscription system-service category

In the payment system, consumers need to pay a monthly fee or an annual fee to become a VIP. Generally speaking, there must be a solid consumer base.After all, it is difficult for you to make a new user become a paying member with little contact with you, so this payment system is basically used to maintain experienced users.

In addition, this payment system must have membership benefits, otherwise users don’t have to pay you in vain.

The most classic case is Amazon. Now Prime with an annual fee of $119 only needs $79 at the earliest, but only one problem was solved in that year, that is, it was guaranteed to be delivered free of charge within 2 days. This was the biggest problem of e-commerce in that year, otherwise a product would only be available in 2-3 weeks, and even if the price was superior, it could not wait.

Later, many functions were added to Prime for free, such as Amazon music, Amazon photos (unlimited storage of photos) and Amazon videos.(Watch all kinds of movies, dramas and original dramas at will)Wait a minute. In 2018, according to data from investment bank JP Morgan, the annual membership fee of $119 is worth about $784, which can be said to be over-valued.

The extreme, even extreme, is Costco.After covering the cost of goods, personnel and management expenses, the income generated by its goods is almost used up, so that its final profit returned to shareholders and membership fees are almost equal.

Third, the paid subscription system-commodity category

Another logic of the payment system is, "subscription box.（Subscription Box）Type ",that is, the subscription of physical items such as products/commodities.

The goods in the "subscription box" generally need to be purchased repeatedly. Take Bean Box as an example, it is the subscription of coffee-normal purchase is the normal price, but if you subscribe, you can always receive coffee on schedule within a cycle, and you can enjoy a discount.The essence is a behavior of directly locking consumers and locking demand, and then it may be the reverse supply chain.

Another advantage of this subscription is that it can increase the lifetime value of customers-from the case of Bean Box, can it be the same if you let consumers buy once and realize repeated service for six months, and let consumers buy for one month and one month?

Amazon has a similar service, and some products can be "subscribed" directly on the purchase page-usually with a discount of about 5%.

Fourth, the charity system

Discount can be a component of the membership system, but it is not necessary.

Therefore,The logic of the charity system is that you are attracting consumers with your own values, thus establishing a stronger relationship.The more common way is that enterprises donate a percentage of their income to charity, such as donating the money to charities, disease research institutions, animal protection organizations and so on.

A small evolutionary version here is that the enterprise will give you several optional donor institutions, and you can choose the one you are willing to donate. This is the case with The Body Shop in America, which introduced animal welfare into its membership system.

In addition to receiving rewards and VIP treatment, consumers can also choose to donate a percentage of their spending to Born Free USA, an animal welfare institution. This is also because The Body Shop has always emphasized environmental responsibility.

This logic lies in that the communication with consumers is not only the exchange of goods and services, but also the integration of values, which in turn makes the loyalty of consumers come to a different and uncontested field.It can be said to be a "blue ocean strategy of values".

V. Sharing cooperation system

A consumer will not only have a membership card, so the demand is also diverse. It can be said that consumers’ spending time is very idle, and the core is whether businesses from different formats can "cut leeks" together-buy electronic products from you, shoes from me and snacks from him.

Therefore, consumers will also want more flexibility in rewards. At this time, what is needed is cross-industry cooperation, which is equivalent to consumer sharing. After all, every enterprise has private domain traffic and data is single-segmented. If(Where permitted by law)Realize the docking of data, then almost draw the whole life of consumers.

In the United States, Nike’s membership system is like this. It has cooperated with Apple, Classpass and Headspace. These companies are not randomly selected, but can be linked to sports. They belong to the cooperation of several enterprises with sports as their core values.

At the same time, Nike also has a variety of apps for different sports to help members achieve their exercise goals. Then as long as the consumer’s behavior can be recorded by the App, then you can get a reward.

Japan’s Sakya Bookstore is also this logic, which focuses on life: through the T-card system, the parent company of Sakya Bookstore has opened 887,000 stores in 179 Japanese companies in May 2018, realizing the universality of points, and the profit does not come from the points themselves, but from the big data insight of consumers. Because consumer data is no longer just a single book purchase, eating, shopping, but all the synthesis.

In China, this kind of cross-industry cooperation is also gradually emerging. For example, JD.COM Plus can give you an iQiyi member.It is also the opening of data and traffic sharing between the two parties, which in turn turns traffic into "reservation".

VI. Community system

Beauty cosmetics brand Sephora（Sephora）Beauty Insider, a membership system, must be said. On the one hand, this system can be upgraded to three grades based on consumption, and every dollar spent in each grade can get different grades of points feedback.(1 dollar for 1 point, 1.25 points, 1.5 points respectively)At the same time, there are opportunities to get more exclusive services with the improvement of grades in the traditional "hierarchical system".

Besides,The biggest feature of Sephora’s membership system is the establishment of a community-to communicate with various members, find inspiration, participate in exclusive activities and so on.At this time, members of Sephora come to the brand community, and Sephora can understand the needs of consumers and then optimize its product design.

This logic also exists in China, that is, in Xiaomi’s community, a group of fans gather in the community to communicate with each other and put forward their own needs, and Xiaomi’s product manager can collect relevant information and update the corresponding system: users feel that they are valued, and Xiaomi has obtained consumer demand and met consumer demand, and both sides are happy.

Seven, TOKEN type

The last one is the TOKEN logic in the blockchain, or,Is similar to "asset securitization"（ABS）The idea of "assets token" should be called as a kind of "assets token"（ABT）”。

This kind of logic can be seen in China. At present, it can be simply divided into two types. The first type is "commodity tokenization", which is represented by the second-hand e-commerce enjoyment theory, and the second type is "behavior tokenization". I think the representatives are interesting headlines and today’s headlines. Let’s look at it together:

"Commodity Tokenization"

The problem with second-hand e-commerce is that the seller wants to sell an item that is "emotionally connected with himself", and based on game theory, the buyer will directly regard all second-hand goods as having a problem, forming a "lemon market effect" and paying a very low price, or, no matter how wonderful your price is and how perfect the goods are, I will ask for a 20% discount first and then post it-as long as I have sold something on idle fish once.

This will greatly reduce the efficiency of the transaction, and the seller will usually feel very uncomfortable, and finally there may be problems on the "supply side", which will have a negative effect on the market.

The logic of enjoying things is very interesting, that is, instead of introducing money, users use small red flowers. Users earn small red flowers through various behaviors, such as signing in and sharing, and then "exchange" other people’s goods with their own small red flowers. Because the little red flower is not anchored with the RMB, so,Users will participate in the purchase according to their real needs, rather than the "chopping behavior" caused by "consumerism".As a result, the pressure on both buyers and sellers is reduced, which greatly promotes the circulation efficiency of goods.

This logic actually exists in offline channels, that is, "moon cake tickets", that is, the moon cakes are placed there, and the person who finally gets the tickets goes to a specific place to pick up the goods. As for the intermediate process-the goods are not moving, and the tickets are flying around, which greatly reduces the cost. The logic of this set of freight tickets is "online" and combined with the mode of second-hand e-commerce, which forms the theory of enjoying things.

"Behavior Tokenization"

The second logic is "behavior token", which is the case with interesting headlines.

To put it simply, users can be rewarded for all their behaviors on the APP, including reading gold coins, watching videos, sharing gold coins, and rewarding users with "tokens" in a different way, and then this "token" is every cycle.(The period of interesting headlines is "1 day")Will be cleared, converted into RMB, accumulated to a certain amount, you can withdraw cash-or buy other goods directly in the APP.

The logic is simple,Retaining customers requires costs, so why not give these costs directly to customers as much as possible?And these sources of RMB are also simple, just divide the gross profit of each cycle directly. So now, we will find that many apps have this logic, such as the extreme version of today’s headlines, various headline apps, and various information apps.

Related links:"Integral Incentive System" from the Perspectives of JD.COM, Interesting Headlines and Amaya.

This article comes from WeChat WeChat official account:Retail Watch (ID: On Retail), author: Wang Ziwei

Albinism is a kind of hereditary leukoplakia caused by melanin deficiency or synthesis disorder of skin and accessory organs due to tyrosinase deficiency or functional decline.

According to clinical manifestations, albinism can be divided into three categories: ocular albinism (OA), ocular skin albinism (OCA) and albinism-related syndrome, among which ocular skin albinism (OCA) is the most common and albinism-related syndrome is the rarest.

This paper mainly expounds the clinical manifestations, genetic causes and genetic counseling of OA and OCA.

Clinical manifestations of OA and OCA

Only the eye pigment in OA patients is reduced or lacking, while the eye, skin and hair in OCA patients are obviously reduced or lacking.

1, eye performance

① Iris transillumination defect (TID)-91% ~ 100% albino patients have TID.

② nystagmus

③ Fundus hypopigmentation —— It is caused by the decrease of retinal pigment epithelium and/or choroidal pigmentation, which often leads to obvious choroidal vessels in the posterior pole. It is reported that more than 94% patients with albinism have fundus hypopigmentation.

④ hypoplasia of fovea-characterized by the continuation of the inner layer of retina behind fovea and the decrease of cone photoreceptor specialization.

⑤ optic nerve abnormality

⑥ ametropia

2. Skin manifestations

The skin and hair color of albino patients may change with age.

① Skin and hair pigmentation score

Skin and hair pigmentation scores help to objectively determine the influence of hypopigmentation.

② Skin diseases

Including all albinos, regardless of skin color, the risk of ultraviolet (UV) light-related skin diseases will increase. The most important of these is skin cancer, which includes squamous cell carcinoma, basal cell carcinoma, melanoma and less common Merkel cell carcinoma.

Genetic causes of OA and OCA

The following table summarizes the genes known to be related to nonsyndromic OCA and OA. All nonsyndromic OCA are inherited by autosomal recessive mode. OA (always non-syndrome) is inherited in an x-linked manner.

The following table summarizes the genes known to be related to OCA syndrome:

Genetic counseling

1. Inheritance mode

Nonsyndromic ocular skin albinism (OCA) caused by pathogenic variation in TYR, OCA2, SLC45A2, SLC24A5, LRMDA (C10orf11) or DCT (TYRP1) is inherited in autosomal recessive way.

Ocular albinism (OA) caused by pathogenic variation in GPR143(OA1) is inherited by X linkage.

If an individual suffers from a specific syndrome related to OCA (such as Hermansky-Pudlak syndrome or Chediak-Higashi syndrome), genetic counseling is needed for this disease.

2. Autosomal recessive inheritance-risk to family members

Parents of the proband:

The parents of the affected children are presumed to be heterozygotes causing the pathogenic variation of OCA.

If molecular diagnosis has been established in the proband, it is suggested that the parents of the proband should be tested for molecular genes to confirm that both parents are heterozygotes causing the pathogenic variation of OCA and allow reliable recurrence risk assessment.

If the pathogenic variation is detected only in one parent, and the parental identity test has confirmed biological motherhood and parent-child relationship, one of the pathogenic variations identified in the proband may occur as a newborn event in the proband or as a zygote in the mosaic parent. If the proband seems to have homozygous pathogenic variation (that is, the same two pathogenic variations), other possibilities to be considered include:

The deletion of single exon or multiple exons in the proband was not detected by sequence analysis, which led to artificial homozygosity;

Parental chromosomes and single parent homomorphism of pathogenic variation lead to homozygosity of pathogenic variation among proband.

Heterozygotes (carriers) are asymptomatic and have no risk of developing the disease.

Siblings of the proband:

If it is known that both parents are heterozygotes of pathogenic variants that cause OCA, each sibling of the affected individual has a 25% chance of being affected at conception, a 50% chance of becoming asymptomatic carriers, and a 25% chance of inheriting any familial pathogenic variants.

Heterozygotes (carriers) are asymptomatic and have no risk of developing the disease.

Descendants of the proband:

The offspring of autosomal recessive OCA individuals are obligate heterozygotes (carriers) that cause the pathogenic variation of OCA.

Other family members:

Every brother and sister of the proband’s parents has a 50% risk of becoming the carrier of OCA’s pathogenic variation.

Carrier detection:

It is necessary to identify the pathogenic variation that causes OCA in the family in advance for carrier detection of at-risk relatives.

3. X-linked inheritance-risk to family members

Parents of male proband:

The father of the affected man will not suffer from this disease, nor will he be a hemizygote of the pathogenic variant GPR143; Therefore, he does not need further evaluation/testing.

In a family with more than one affected individual, the mother of the affected male is an obligate heterozygote. Note: If a woman has more than one affected child and no other affected relatives, and if family pathogenic variation cannot be detected in her white blood cell DNA, she is likely to have germline chimera.

If the male is the only affected family member (i.e., a simple case), the mother may be heterozygote, the affected male may have new pathogenic variation (in this case, the mother is not heterozygote), or the mother may have somatic/germline chimera.

It is suggested that the mother should be tested for molecular genes to confirm her genetic status and make a reliable recurrence risk assessment.

Brothers and sisters of male proband:

The risk of siblings depends on the mother’s genetic status:

If the proband’s mother has the pathogenic variation of GPR143, the chance of transmission in each pregnancy is 50%.

Men with genetic disease variation will be affected;

The female with genetic pathogenic variation will be heterozygote (i.e. carrier). Heterozygotes are usually unaffected, although they can show iris penetration defects, "mud splash" fundus appearance and fovea hypoplasia.

If the proband represents a simplex case and the pathogenic variation cannot be detected in the mother’s leukocyte DNA, it is assumed that the risk of sibs is low, but the risk is higher than that of the general population because of the possibility of maternal lineage mosaic.

Descendants of male proband:

The affected men spread the disease-causing mutation of GPR143 to all their daughters, but not to their sons.

Other family members:

Menstruation and maternal cousins of the male proband may be at risk of GPR143.

Note: Molecular genetic testing may be able to identify family members with new pathogenic mutations, and this information can help determine the genetic risk status of large families.

Heterozygote detection:

To identify female heterozygotes, it is necessary to identify the pathogenic variation of GPR143 in the family in advance.

Note: As carriers of this X-linked disease, women are heterozygotes, which are usually not affected, but they may show iris penetration defects, "mud splash" fundus appearance and fovea hypoplasia.

Source | Metz Medical official website

Write | ｜Anna.An

Original title: Inheritance and Manifestation of Albinism

Read the original text

　　Recently, various provinces and cities have successively disclosed the practical projects of people’s livelihood in 2025 and the provincial budget. According to statistics, up to now, more than ten provinces, including Beijing and Sichuan, have carried out or planned to carry out free vaccination programs for provincial-level female HPV vaccine.

　　According to the agency, with the successful completion of phase III clinical trials and the release of production capacity of HPV vaccine under research in China, the indications are extended to male population.ChinaThe market scale of HPV vaccine will continue to expand, and it is expected to reach 62.54 billion yuan in 2031.

　　Multi-provincial promotion

　　Since the beginning of this year, many provinces have indicated that they will launch a free vaccination program for HPV vaccine for school-age women.

　　Recently, Sichuan Province disclosed the "Report on the Implementation of the Budget in Sichuan Province in 2024 and the Draft Budget in 2025", which proposed to allocate 4.41 billion yuan for public health services. Improve the financial subsidy standard for basic public health services, support the implementation of "two cancers" free screening for school-age women, support the free vaccination of domestic bivalent HPV vaccine for eligible school-age girls, and increase support for AIDS prevention and treatment.

　　On January 26th, the General Office of the Beijing Municipal People’s Government issued the notice of "Important Livelihood Projects in Beijing in 2025", and Beijing will voluntarily vaccinate human papillomavirus vaccine for new girls in Grade One in 2025.

　　On January 10th, Tianjin Municipal Health and Health Commission formulated 16 measures to serve Tianjin Health and Health Kang Weimin in 2025, and explicitly launched the public welfare vaccination activities of reducing or exempting 450,000 doses of bivalent HPV vaccine for women aged 9-45.

　　In 2025, the work report of Yunnan provincial government put the implementation of "children’s health care and protection""Huimin Project" is listed as one of the 10 practical things to be done in 2025, and it is clearly put forward that domestic HPV vaccine should be vaccinated free of charge for eligible junior one girls in the province according to the principle of informed and voluntary.

　　In January this year, the government work report for 2025 released by Gansu Province made it clear that in 2025, we will continue to make overall arrangements for financial resources and do 10 practical things for the people, one of which is to subsidize HPV vaccination for 100,000 school-age girls on the premise of "knowing, volunteering and subsidizing".

　　In October 2024, National Health Commission held a press conference to disclose that since 2021, 11 provinces including Guangdong, Hainan, Fujian, Jiangsu, Jiangxi, Chongqing, Tibet, Zhejiang, Shandong, Hubei and Guangxi, as well as Zhengzhou,Chengdu and other cities have included HPV vaccination in the government’s practical projects for the people, and provided free HPV vaccination services for school-age girls aged 13-14 in the region through financial purchase services and fixed subsidies. Up to now, the policy of free HPV vaccination has covered about 40% of school-age girls in the country.

　　Speed up research and development

　　On January 8,It was announced that a number of new indications of tetravalent human papillomavirus vaccine (Saccharomyces cerevisiae) (trade name: Jiadaxiu, also known as tetravalent HPV vaccine) have been approved for marketing in National Medical Products Administration, which is suitable for male vaccination aged 9-26. This is the first HPV vaccine approved for male vaccination in China. Subsequently, many places announced the start of male HPV vaccination.

　　HPV infection is one of the most important public health problems in the world. Vaccination is the best way to prevent cervical cancer and other HPV-related cancers. Recently, in order to further respond to WHO’s Global Strategy for Accelerating the Elimination of Cervical Cancer, the International Papillomavirus Society needs to achieve the phased goal of "90-70-90" in 2030, and actively appeals to all countries to adopt a vaccination plan for both men and women as soon as possible, that is, to promote HPV vaccine equally to school-age boys and girls, so as to expand the coverage of vaccination and maximize the immune effect of the group.

　　Research and development of domestic nine-valent human papillomavirus vaccine is accelerated. A few days ago,It is said that the work of the phase III clinical study of the subsidiary Shanghai Zerun nine-valent HPV vaccine continues to advance. At present, the phase III clinical trial comparing the immunogenicity of this vaccine with similar vaccines is in the stage of data statistical analysis and writing clinical research reports. Based on the clinical development plan of nine-valent HPV vaccine products, the company is keeping close communication with National Medical Products Administration Drug Evaluation Center, and actively striving for the best strategy to promote the clinical research on protective efficacy.

　　At the end of August 2024, it was announced that the company’s nine-valent HPV vaccine marketing license application was accepted. After the application for registration of the nine-valent HPV vaccine is accepted, it still needs to go through comprehensive evaluation, on-site verification and other procedures, which will not have a significant impact on the company’s financial situation and operating performance in the short term. After being approved for listing, it will be conducive to the promotion and use of the company’s HPV vaccine, enrich the company’s product line, further enhance the company’s core competitiveness and lay a solid foundation for the company’s sustained and steady development.

　　Many domestic vaccine companies are also competing for the HPV vaccine market for male indications. In November 2024, it was revealed that the nine-valent HPV vaccine for male population was approved for clinical trials. In addition, on February 12, 2025,Ruike biologyIt was disclosed that the application for clinical trial of the new adjuvant recombinant nine-valent HPV vaccine developed by the company for male population was accepted in National Medical Products Administration.

　　It is estimated that its nine-valent HPV vaccine (female indication) will be submitted in China and Indonesia respectively in 2025.License application (BLA), nine-valent HPV vaccine (male indication) is expected to be submitted to BLA in 2027.

　　open-sourceIt is predicted that with the successful completion of the third phase clinical trial of HPV vaccine and the release of its production capacity, its indications will be extended to the male population, and the vaccination awareness of the target population will continue to increase, and the market scale of HPV vaccine in China will continue to expand, which is expected to reach 62.54 billion yuan in 2031.

　　ASEAN countries are located at the intersection of land and sea in the Belt and Road Initiative, and are key areas for high-quality joint construction of the Belt and Road Initiative. In the past 10 years since the Belt and Road Initiative was put forward, from economic and trade exchanges to cultural exchanges, China-ASEAN Expo’s circle of friends has become larger and larger, and its outward attraction has become stronger and stronger.

　　— — — — — — — — — —

　　The 20th China-ASEAN Expo came to an end not long ago, but the vision of China and ASEAN countries meeting challenges together and building a closer China-ASEAN destiny community is inspiring people to move forward.

　　"This year, the Chairman of the Supreme Leader proposed to build a closer China-ASEAN destiny community and jointly build ‘ Belt and Road ’ The 10th anniversary of the initiative is also the 20th anniversary of the founding of China-ASEAN Expo and China-ASEAN Business and Investment Summit (hereinafter referred to as "China-ASEAN Expo" and "Summit" respectively). China — Wei Zhaohui, Secretary-General of the ASEAN Expo Secretariat, said that since China-ASEAN Expo and the Summit were held for 20 years, the bilateral trade volume between China and ASEAN has grown at an average annual rate of more than 13%, which has promoted the two sides to become each other’s largest trading partners and the most active partners in mutual investment, and helped to build a new pattern of China-ASEAN opening up at a higher level.

　　According to Xu Ningning, executive director of the China-ASEAN Business Council, ASEAN countries are located in the land-sea intersection of the "Belt and Road" and are key areas for building the "Belt and Road" with high quality. In the 10 years since the "Belt and Road Initiative" was put forward, China-ASEAN Expo has closely followed China — The needs of the times of ASEAN cooperation, constantly expand the functions of the platform, and promote the implementation of China — A series of consensus documents, joint statements and action plans reached by ASEAN have deepened China’s trade, investment, interconnection and regional cooperation with ASEAN countries, which is also the way to China-ASEAN Expo’s enduring success.

　　Inter-regional complementary resources promote active investment and trade.

　　The theme of the 20th China-ASEAN Expo is "Building a Home with Harmony, Destiny and Common Future — — Push ‘ Belt and Road ’ High-quality development and building an economic growth center. " At the meeting, many exhibitors expressed that they felt the dividends brought by the complementary market resources and factor flow between China and ASEAN. Zhu Qiugen, from Xishuangbanna, Yunnan, talks about tea at the exhibition during the day and packs tea for customers from all over the world in the hotel at night.

　　This year is his second time in China-ASEAN Expo, and he found that many tea lovers used to look at the price but now at the quality. "More and more customers have found me for the fragrance of tea, and people who understand the good products have found it. This change is more gratifying than how much tea I have sold."

　　Zhu Qiugen deals in ancient tea from Laos. The local tea garden employs local people to pick fresh tea and process it into "wool", and then it is transported to Xishuangbanna via China-Laos Railway for further processing to make a series of products such as tea cakes and tea bricks. Zhu Qiugen also founded the brand of "Laos Ancient Rhyme Tea Industry".

　　In recent years, thanks to the convenience of transportation and policies, Zhu Qiugen went deep into the country of origin and built a relatively complete industrial chain from picking, research and development, production and sales. "Let customers drink a cup of ancient tree tea that really comes from the mountains, without middlemen." In this way, the quality and cost have been well controlled.

　　The tea consumption market in China is huge, and the demand for high-quality tea has become a trend. Zhu Qiugen thinks that tea is a gentle lifestyle and a product that pursues quality of life. However, the domestic resources for picking ancient tree tea are limited, and some merchants have false propaganda and shoddy to some extent, which makes many consumers hesitate to buy.

　　In 2015, Zhu Qiugen just arrived in Laos, and he was doing hotel business at that time, but soon the local ancient tree tea fragrance caught his attention. In Laos, the unique and closed natural environment creates the good quality of Laos ancient tree tea, but these teas are mostly sold as agricultural products. "Laos has raw materials, and China has a market, so the connection naturally arises." Zhu Qiugen said.

　　With the opening of China-Laos Railway, Zhu Qiugen’s tea business has more convenient transportation conditions. If the tea is to be sold to Nanning market, Zhu Qiugen will choose to go by sea through Vietnam, which is "more cost-effective".

　　Guangxi is the only land-sea connecting region between China and ASEAN. The coastal, border and riverside areas of China-ASEAN Industrial Cooperation Zone are the frontier and window of Guangxi’s opening to the outside world. Relying on the existing parks in Nanning, Beihai, Fangchenggang, Qinzhou, Yulin, Baise and Chongzuo, Guangxi has integrated the construction of China-ASEAN Industrial Cooperation Zone, creating a development pattern of "one city, one area, one park". At present, many areas in the cooperation zone have achieved seamless traffic connection with ASEAN countries. For example, Chongzuo area is 180 kilometers away from Hanoi and Nanning, the capital of Vietnam, and there are four national first-class ports around it, which is the most convenient land international passage from China to Indo-China Peninsula.

　　"In July this year, Liuzhou Economic and Trade Delegation and 32 key enterprises went to Southeast Asia to carry out economic and trade exchange activities." Yao Fang, deputy director of the Management Committee of Liuzhou Economic and Technological Development Zone, said that the well-known domestic new energy automobile brands with factories in Liuzhou have actively gone abroad, and now they have sales markets in 72 countries and regions around the world.

　　The vigorous market demand drives the pace of transportation infrastructure construction. Sima Zhe, senior economist of the Asian Infrastructure Investment Bank and head of the ecosystem of the Ministry of Economic Affairs, said that in 2021, the AIIB provided 300 million US dollars to support the improvement project of border connectivity in Chongzuo, Guangxi, which improved the efficiency of cross-border connectivity around Shuolong Port and strengthened the economic and trade activities between China and Viet Nam.

　　In terms of commodity trading, the exchanges between Guangxi and ASEAN have become increasingly close. Guangxi is rich in commodity resources, with the output of white sugar, wood and raw silk ranking first in the country, and the output of alumina, pigs, pulp, Chinese herbal medicines and non-ferrous metals ranking first in the country. At the same time, Guangxi is also an important import port for ASEAN-specific commodities such as wood, non-ferrous metals, oil and gas, coal and fruits.

　　Li Kaizhou, deputy director of the local financial supervision bureau of Guangxi Zhuang Autonomous Region, said that in recent years, Guangxi has seized green opportunities, deepened cooperation with ASEAN, built a pilot free trade zone with high quality, and actively created a convenient place for domestic and international dual-cycle markets. The construction of new land and sea channels in the west has been accelerating. From January to July this year, Guangxi’s import and export to ASEAN was 188.08 billion yuan, a year-on-year increase of 71.6%.

　　Adhere to joint business and win-win sharing.

　　Wei Zhaohui, Secretary-General of China-ASEAN Expo Secretariat, said that since the China-ASEAN Expo and China-ASEAN Investment Summit were held 20 years ago, 196 Chinese and foreign leaders, more than 4,100 ministerial-level VIPs and heads of international organizations attended, which was accompanied by friendly relations between China and ASEAN and grew together with the construction of China-ASEAN Free Trade Area.

　　"China-ASEAN Expo has been successfully held for 20 years in a row, thanks to the unique exhibition mode. This is the successful password for China-ASEAN Expo to do something new and better." Wei Zhaohui introduced.

　　Adhere to business cooperation and win-win sharing, adhere to the principle of not making profits for ASEAN countries, respect ASEAN’s opinions on major issues, and give priority to meeting ASEAN’s needs in terms of booth arrangement. In this China-ASEAN Expo, the scale and proportion of ASEAN exhibitions remain the largest in China International Exhibition, and seven countries including Indonesia, Malaysia and Viet Nam have resumed their pavilions and restored ASEAN’s "Charming City" exhibition area.

　　Wei Zhaohui introduced that in all aspects of exhibition preparation, we should respect the ASEAN way, take care of ASEAN wishes, and always adhere to the value concept of "10+1>11". The ministers of economy and trade of China and 10 ASEAN governments and the ASEAN Secretary-General will serve as co-directors of the organizing committee, the directors of departments in charge of various countries will serve as deputy secretaries-general, and the directors will serve as liaison officers. Major issues will be discussed by the organizing committee meetings and senior officials meetings.

　　"International Friendship City Entering Dongbo" is also a highlight of the exhibition in recent years. According to the data of Foreign Affairs Office of Guangxi Zhuang Autonomous Region, at present, Guangxi has concluded 128 pairs of international sister cities with 39 countries, ranking fourth in the country. During this visit to China-ASEAN Expo, more than 30 sister cities from nearly 20 countries participated in the exhibition with their own special products.

　　"Before, our market was mainly concentrated in Jiangsu, Zhejiang and Shanghai. I never thought that the products could radiate to the inland of China and even ASEAN countries." Hong Yongwang, representing Zaragoza, Spain, said that Zaragoza and Yulin, Guangxi Zhuang Autonomous Region are international sister cities. Entrusted by the Zaragoza municipal government, Hong Yongwang brought more than 160 products including red wine, ham and olive oil to the site in China-ASEAN Expo.

　　Last year, the double-deck sinking square of Nahong Interchange Station of Nanning Metro, designed and built jointly by Nanning and Crema, Italy — — Friendship City Metro Plaza was officially completed, becoming the first subway station space in China that was fully decorated and designed by International Friendship City. At this year’s China-ASEAN Expo, exhibitor Zhang Xiaowei brought a painting entitled "Table Culture" to the scene to explain the Italian wine culture to the audience, and the author of this painting, Marilisa Leon, is the designer of the subway station space. Stephania Bonaldi, mayor of Crema, Italy, commented: "The design of the square is closely related to the theme of the Silk Road, which has brought the cultural ties between China and Italy closer and the two countries and peoples closer."

　　Institutional opening stimulates new kinetic energy of cooperation

　　From economic and trade exchanges to cultural exchanges, China-ASEAN Expo’s circle of friends is getting bigger and bigger, and its outward attraction is getting stronger and stronger. In the process of cooperation between China and ASEAN countries, many institutional and mechanistic modes of cooperation and dialogue have gradually taken shape.

　　During this year’s China-ASEAN Expo, a side event on the theme of "Institutional Opening: A New Pattern of Regional Economic Development" was held for the first time, and the "ASEAN National Standardization Cooperation and Exchange Center" was officially unveiled. The ASEAN cross-border e-commerce digital intelligence service platform and the e-commerce exchange center of the digital economy industrial park were announced to be open.

　　According to customs statistics, from January to August this year, the total import and export value of China to countries that jointly built the Belt and Road Initiative reached 12.62 trillion yuan, up 3.6% year-on-year, of which food trade reached 553.82 billion yuan, up 10.4% compared with the same period of last year and 162% compared with the same period of 2013. On the eve of the opening of China-ASEAN Expo, the Nanning Declaration on Customs Food Safety Cooperation on the Belt and Road was issued, and all parties signed the articles of association of the cooperation mechanism.

　　The perfection of the mechanism and articles of association aims at more convenient, long-term and stable factor flow. It is the consensus of many enterprises that "there is vitality when there is mobility, and there is market when there is mobility".

　　Last year, Guangxi Xinzhong Industrial Investment Co., Ltd. cooperated with the secretariat of China-ASEAN Expo to build a China-ASEAN special commodity gathering center. He Yan, the company’s deputy general manager, hopes that after participating in China-ASEAN Expo, economic and trade activities will continue for a long time through 17 offline pavilions and online platforms, and continuous economic and trade exchanges will take place with ASEAN countries in 365 days.

　　The international situation is complex and changeable, but the potential of the ASEAN market is constantly being released. "The number of ASEAN regional offices has grown particularly fast, exceeding our growth rate in China." Through this detail, Bo Yu, managing partner of PricewaterhouseCoopers Consulting (Shenzhen) Co., Ltd., found that the ASEAN market is being regarded as a growth point in the future, both in China and the world.

　　Bo Yu further analyzed that people value the population and future growth of ASEAN, and the population structure is relatively young. He believed that Guangxi should make good use of the role of "bridgehead".

　　As an Indonesian enterprise, Jinguang Group has been rooted in China for more than 30 years. Zhai Jingli, vice president of Jinguang Paper (China) Investment Co., Ltd., a subsidiary of Jinguang Group, believes that enterprises can make use of the cumulative rule of regional origin of RCEP and the advantage of the shortest and most convenient industrial supporting distance between Guangxi and ASEAN to expand the ASEAN market and play a good "ASEAN brand".

　　At present, some ASEAN countries have many environmental problems, such as soil degradation, water shortage and air pollution, which have affected local agricultural production and tourism and damaged local economic development to some extent. With the increasing demand for environmental protection in ASEAN countries, China’s environmental protection industry has gradually entered the ASEAN market. Hong Tao, director and professor of business economics research at Beijing Technology and Business University, pointed out in the China-ASEAN Forum on Innovation and Development of Commodity Trading that the effective implementation of RCEP has provided new impetus and cooperation foundation for promoting green recovery of regional economy, low-carbon development and global economic recovery, and reduced the cost of environmental protection industry in China.

　　In the past 20 years, the cooperation between China and ASEAN in the field of energy and electricity has been equally fruitful. By the end of August this year, China Southern Power Grid had been connected with the power grids of ASEAN countries through more than 10 circuits of 110 kV and above, achieving a total cross-border two-way power trade of nearly 70 billion kWh, of which clean energy accounted for over 90%. Hu Tianxiang of China-ASEAN Expo and china huadian Guangxi Company introduced that china huadian has invested in 9 projects under construction in ASEAN, with an installed capacity of 4.66 million kilowatts. In Cambodia, china huadian is the largest foreign power generation operator in Cambodia with an installed capacity of 1.038 million kilowatts under construction.

　　RCEP has entered a new stage of full entry into force and implementation, constantly releasing the strategic potential of economy and trade. Zhou Shi, a researcher and deputy director of the Research Office of the Market and Price Research Institute of the National Development and Reform Commission, believes that the import and export of Hunan and ASEAN countries in China increased by more than 70% in the year when RCEP was implemented, and the import and export of Guangxi to ASEAN countries also increased by 71.6% from January to July this year.

　　In the face of the current complicated and changeable international situation, many exhibitors realized that China and ASEAN are opportunities for mutual development and have great potential for cooperation. China was the first big country to sign and join the Treaty of Amity and Cooperation in Southeast Asia. In 2021, China and ASEAN upgraded their bilateral relations to a comprehensive strategic partnership.

　　Jiangsu Furen Group’s booth area in the 20th China-ASEAN Expo was not large, but the personnel in charge of market, operation and technology all came to the scene in order to better understand the ASEAN market and enterprises. In 2014, Jiangsu Furen Group held Jiangsu Xuzhou Forging Machine Group Co., Ltd., and two years later, it successfully acquired German EBU Forming Technology Co., Ltd. "This also marks that China Press has begun to rank among the world’s advanced manufacturing." Li Wei, deputy general manager of Xuforging Group, said that due to the rapid development of Thailand’s automobile industry in recent years, many internationally renowned automobile companies have invested and built factories in Thailand, and the export of intelligent forging equipment of Xuforging Group to Thailand has also increased by 20%-30%.

　　"The ASEAN market is becoming a new strategic growth point, especially in terms of labor structure, operating costs and market potential. The implementation of RCEP has also provided us with a stable and efficient supply chain network." Li Wei is full of expectations for the development of enterprises in the ASEAN market and the prospect of international cooperation. "We will also continue to enhance the technological breakthrough capability of intelligent manufacturing and better go abroad." (Zhongqing Daily Zhongqing Net Trainee Reporter Wang Junli Reporter Xie Yang Intern Zheng Quan)