Affected by this round of "refrigerator-level" cold wave, freezing rain and snow occurred in Lechang, Ruyuan and Nanxiong in Shaoguan City, which is located in the alpine mountain area of northern Guangdong Province, resulting in the interruption of many roads, among which the northern section of Shaoguan (Beijing-Zhuhai-North) of Beijing-Hong Kong-Macao Expressway was closed for more than 100 hours by noon on January 26th due to road icing and snow.

On the 30th, the reporter learned from the traffic police department of Shaoguan Expressway that although the traffic police department has separately diverted vehicles to Guangle Expressway at Ruyuan Toll Station Interchange in the northbound direction of Beijing-Zhuhai and Pingshi North Interchange (K5) in the southbound direction since the early morning of the 26th, there are still vehicles that "mistakenly entered" Beijing-Zhuhai North and stayed on the icy expressway.

On the morning of January 29th, Shaoguan high-speed traffic police found a large truck with Zhengzhou license plate in Henan parked on the expressway when they were inspecting the Beijing-Zhuhai North Bridge section which had been closed due to snow and ice. The traffic police came forward to ask and learned that the driver of the large truck "mistakenly broke into the restricted area" when passing through the traffic control section and drove to the icy section, so the vehicle could not move on and it was worth stopping on the road. The traffic police department immediately sent a batch of food and warm items for the drivers of large trucks to resist hunger and cold.

At noon on the 30 th, the road icing situation near the parking position of the big truck improved. The traffic police department immediately assisted the driver of the big truck to install anti-skid facilities and commanded the big truck to slowly reverse and leave the expressway.

On the morning of 29th, during an interview in Ruyuan Bridge Town, the reporter found that a car with Shenzhen number plate was parked on an icy uphill section of Bridge Town on G240 National Highway, and the windshield, rearview mirror and body were covered with a thick layer of ice and snow, and the car was empty. A triangular warning sign was placed about 30 meters behind the car, and the car was suspected to have been temporarily "abandoned" by its owner.

The roads with snow and ice are prone to traffic accidents. The picture shows the traffic police urgently handling the accident vehicles on Guangle Expressway.

The traffic police reminded the majority of car owners not to drive on ice and snow roads as much as possible, especially most Guangdong drivers who lack experience in driving on ice and snow roads. If they must drive on ice and snow roads, they should install snow chains as much as possible, and try to keep driving at a constant speed during the driving process. If there are wheel tracks in front of them, they can follow the rut; When the vehicle is accelerating, lightly step on the accelerator to prevent the driving speed from suddenly rising and slipping, or the two wheels encounter different resistances during the rapid acceleration, resulting in lateral sliding; Don’t hit the steering wheel when driving, slow down in advance when turning, and increase the turning radius appropriately to prevent sideslip.

At the same time, the traffic police reminded that because the friction of ice and snow pavement is smaller than that of dry pavement, it is necessary to increase the safe distance during driving to prevent rear-end collision. Don’t slam on the brakes when braking. The correct way is to "point the brakes" and use the engine to slow down the speed. When parking, park in a sheltered and flat place as far as possible. When parking on a slope road, it is necessary to prevent the car from slipping. Bricks or stones can be used to pad the bottom wheel position.

　　"Low carbon" is one of the hottest words at the two sessions this year. CPPCC members’ proposals are piled up with "low carbon", and NPC deputies discuss "low carbon" hotly, and group discussions are also inseparable from the topic of "low carbon". "Low carbon" has become the "new favorite" that people pay attention to for a time. So, what is "low carbon" and what does agriculture and rural areas do in developing low carbon? The insights of the deputies explain the "low carbon" of agricultural and rural development from different angles.

　　The meaning of the transformation of agricultural development mode

　　"Low-carbon agriculture is first of all an idea and a development direction of agricultural transformation development mode. The essence of the low-carbon concept is to save energy. " Shang Xunwu, member of Chinese People’s Political Consultative Conference and deputy director of Gansu Agriculture and Animal Husbandry Department, said.

　　Zhang Quanguo, member of Chinese People’s Political Consultative Conference and dean of the School of Mechanical and Electrical Engineering of Henan Agricultural University, further explained low-carbon agriculture. He said: "Agriculture, as the basic industry of the national economy, is one of the main sources of greenhouse gases, and it is also increasingly affected by the greenhouse effect. How to formulate low-carbon agricultural development policies and reduce carbon emissions in agricultural production has increasingly become the focus of attention from all walks of life and one of the key areas to be considered in regional economic development. It is imperative to change the agricultural production mode as soon as possible and develop low-carbon and high-efficiency agriculture. "

　　At present, in China’s agricultural production mode, some production habits do not meet the requirements of low carbon, which is neither economical nor polluting the environment. Taking fertilization as an example, Meng Tieying, deputy stationmaster of soil and fertilizer station in Xincheng County, Guangxi Province, said that because there is a lot of local rain, heavy rain usually causes farmland to be flooded. Traditional fertilization methods make the loss of fertilizer very serious, which not only increases the cost, but also pollutes the environment. Farmers urgently need a fertilizer that can control the release rate. Data show that the low utilization rate of chemical fertilizers in China is the main reason for environmental pollution caused by chemical fertilizers. In addition to crop absorption and utilization and soil residue, more than 50% of nitrogen is not absorbed by crops and lost to farmland, which has caused a series of environmental and food safety problems, such as eutrophication of water, soil hardening, greenhouse effect and degradation of agricultural products quality.

　　Zhang put forward a proposal to develop low-carbon agriculture. He believed that it is necessary to cultivate the management concept of low-carbon agriculture, vigorously promote the innovation of agricultural production system, implement the management assessment responsibility system for energy saving and emission reduction in agriculture-related production, and gradually develop and improve agricultural energy efficiency standards from the height of national laws and regulations. He also proposed that we should pay attention to the research on low-carbon agriculture, including the integrated application research of carbon emission reduction and carbon sink expansion technologies such as energy, environment, building structure, water supply and drainage, and green space.

　　Science and technology support low carbonization of agricultural production

　　Shang Xunwu said that there are many articles that can be done to develop modern agriculture and realize the development of agriculture from extensive to refined. It can be said that in the agricultural field, it is very feasible to achieve low carbon.

　　He said that many aspects of agriculture can consider how to achieve low carbon. For example, he said that from the perspective of agricultural inputs, such as water resources, agriculture consumes a lot of water, but now the way of using water is unreasonable, causing great waste. Water is used for irrigation, but also consumes electricity. If water is saved, irrigation energy is saved, and it is low-carbon.

　　Zhang Quanguo gave a concept of low-carbon agriculture. "Low-carbon agriculture is a modern agricultural development model. Through various means such as technological innovation, institutional innovation, industrial transformation, and new energy development and utilization, energy consumption and carbon emissions are reduced as much as possible to achieve a win-win situation for agricultural production development and ecological environment protection." He further explained that low-carbon agriculture is the further development of eco-agriculture and green agriculture, which not only advocates less use of chemical fertilizers and pesticides and efficient agricultural production like eco-agriculture, but also pays more attention to the reduction of overall agricultural energy consumption and carbon emissions in the process of planting, transportation and processing, when the use of energy such as electricity, oil and gas is increasing.

　　Shang Xunwu gave his own suggestions on how to promote low-carbon agriculture. First, strengthen the role of technology and promote low-carbon technology in agriculture. The second is the innovation of production mode. For example, intensive production, through cooperatives and professional associations to promote centralized production and management, improve efficiency.

　　Zhang Quanguo also holds the same view: supporting the sustainable development of agriculture by improving the technical content of low-carbon agriculture.

　　Taking the scientific and technological development of fertilizer research and development as an example, China has supported the low-carbon fertilization in fertilizer technology research and development. Liu Jianwen, a representative from Agricultural Economics Center of Agriculture Bureau of Linshu County, Shandong Province, said that in recent years, fertilizer enterprises in Linshu have achieved remarkable results in research and development, production and popularization of slow-release fertilizers in low carbon. For example, he said that hundreds of slow-release fertilizer products developed and promoted by Jin Zhengda Group, the largest production base of slow-release fertilizers in Asia, are suitable for field crops in China. Xu Weigang, deputy director of Wheat Research Center of Henan Academy of Agricultural Sciences, summed up the advantages of slow-release fertilizers in low carbon: slow-release fertilizers can control nutrient release according to crop nutrient demand, which changes the shortcomings that fertilizers can not meet the different demands of crops at different growth stages because of rapid dissolution and nutrient loss, and can greatly improve the utilization rate of fertilizers, protect the environment, save energy, simplify crop production technology and help farmers reduce costs and increase income.

　　For supporting the development of low-carbon agriculture with science and technology, Zhang put forward more specific suggestions. He suggested: First, improve the low-carbon agricultural infrastructure in the core grain producing areas. Intensify integration, focusing on the construction of modern facility agriculture demonstration parks, ecological animal husbandry, grain (leafy vegetables) functional areas and other projects to lay a good foundation for accelerating the development of modern agriculture. Second, strengthen the cultivation of excellent varieties adapted to low-carbon environment. At the same time, we should vigorously promote the innovation of farming system and promote a number of development models such as stable grain and high efficiency, farming-pastoral cycle, and paddy-upland rotation. Third, greatly reduce the use of chemical fertilizers and pesticides, and reduce the carbon content in agricultural development. Such as using manure, compost or organic fertilizer instead of chemical fertilizer, and increasing soil nutrients through returning straw to the field.

　　The era of low-carbon rural life is coming.

　　Low-carbon mode not only has great achievements in agricultural production, but also the conditions for developing low-carbon in rural areas are ripe. Zhang Quanguo said that to develop low-carbon agriculture, it is necessary to develop new energy sources in rural areas and realize the diversification of rural energy consumption structure. Such as comprehensive utilization of straw, livestock manure, solar energy and other renewable energy resources to meet the needs of rural domestic cooking energy, rural domestic electricity and domestic hot water.

　　Twenty years ago, Tengtou Village, Ningbo City, Zhejiang Province, which wrote environmental protection into the villagers’ convention and established the only village-level environmental resources protection committee at that time, was the forerunner of rural low-carbon. Fu Qiping, the general secretary of the village party branch, said that building a "low-carbon" ecological village was the golden key to rural development. "To develop a’ low-carbon’ economy and achieve harmony between man and the natural environment, rural areas should also shoulder the burden." Fu Qiping believes that the future "low-carbon" life is a high-quality, healthy and civilized lifestyle.

　　"A large number of solar cookers in the western rural areas will greatly reduce greenhouse gases such as carbon dioxide produced by burning firewood (grass, wood), gas and coal." Ren Qixing, member of Chinese People’s Political Consultative Conference and deputy director of the Population, Resources and Environment Committee, said. He said that the western region of China has a long sunshine time and relatively rich solar energy resources, which is most suitable for popularizing solar cookers in large quantities. Ren Qixing suggested establishing financial support policies and giving appropriate financial subsidies to the purchase of solar cookers in rural areas. At the same time, vigorously support solar cooker manufacturers, give tax incentives, and help enterprises improve output, quality and scientific and technological content to meet the needs of promoting the use of solar cookers in rural areas.

　　Coincidently with Ren Qixing, Hao Yuan, member of Chinese People’s Political Consultative Conference, vice governor of Gansu Province and chairman of the Provincial Federation of Industry and Commerce, is also very concerned about the utilization of solar energy. He put forward the Proposal of Implementing the Solar Energy "South Wall Plan" at the two sessions. Its core idea is to use the south facade of the building facing the sun, including the heat collection wall, air collector and additional sunshine room on the south facade, to convert the collected solar radiation energy into heat energy as much as possible, and then transfer it to the room to achieve the purpose of heating and warming.

　　In order to promote a lower-carbon lifestyle in rural areas, Zhang also suggested that the development and application of biogas technology should be widely promoted, and at the same time, the agricultural and sideline residues should be fully utilized to improve the low-carbon utilization of straw. He said that China’s annual crop straw output is about 700 million tons, half of which can be used as energy, equivalent to 150 million tons of standard coal. He suggested focusing on the research and development of "trinity" complete technology and equipment for low-carbon utilization of straw. The core grain producing areas such as Henan Province are selected to carry out innovative research and demonstration application of low-carbon agricultural renewable energy and energy-saving engineering technology integration.

CCTV News:In Wonsan, the eastern city of North Korea, there is a famous factory that produces leather shoes. The "Yingfengshan" brand leather shoes produced here have excellent workmanship and fashionable styles, which are well received by the Korean people. This factory is Yuanshan Leather Shoes Factory.

At the North Korean National Footwear Exhibition in 2018 and 2019, a leather shoes brand named "Yingfengshan" made a big splash for two consecutive years and won the first prize and the special prize respectively. This brand came from Yuanshan Leather Shoes Factory.

Yuanshan Leather Shoes Factory was founded in 1959 and has a history of 60 years. Kim Jong-un, the current top leader of North Korea, came to Yuanshan Leather Shoes Factory five times since 2014, and it was from 2014 that the development of Yuanshan Leather Shoes Factory entered the fast lane.

CCTV reporter Dong Haitao:This pair of shoes on the exhibition platform was produced in 2007, while this pair of shoes on this side was produced in 2017. It can be seen that there are great differences in texture, design and workmanship between them in the past ten years.

Independent research and development, independent manufacturing and self-reliance

According to the factory commentator, the entire production system of the factory is independently developed by North Korea, and the raw materials for shoemaking are also independently produced by North Korea, while the electricity is provided by national power stations such as Yuanshan Military and Civilian Power Station. They are at the forefront of North Korea’s footwear industry in implementing national policies and realizing self-reliant production, and factory employees are particularly proud.

Zhao Mingshi, head of technical department of Yuanshan Leather Shoes Factory:We received many favorable comments and won the special prize at this spring national footwear exhibition in North Korea.

Cui Hua, a female worker in Yuanshan Leather Shoes Factory:I am a shoe-maker, and I like the ladies’ sandals produced by our factory best. Sandals are women’s favorite footwear products in summer, and we have successfully controlled the weight of women’s sandals within 250 grams.

Nowadays, the vast majority of shoemaking employees in the factory have more than 5 years of shoemaking experience, and the factory will arrange different kinds of leather shoes production plans according to the season, personnel arrangement and product demand.

CCTV reporter Dong Haitao:I’m at the end of the production line of Yuanshan Leather Shoes Factory, where all kinds of leather shoes are displayed. I’m going to have a try now. Let’s try on this pair of pointed leather shoes first. They look very fashionable. The sole is solid and powerful, and it walks steadily. It is a good pair of shoes.

Leather shoes factory is looking forward to expanding production.

Since 2014, the quality of "Yingfengshan" brand leather shoes has been continuously improved, but the price is very close to the people. Take the pair of leather shoes that I just tried on as an example. The ex-factory price is only 25,000 yuan, which is equivalent to about 20 yuan, which is quite good and cheap. The factory commentator told me that the supply of factory products to the Korean people is already in short supply, and they hope to expand production in the future and strive to make "Yingfengshan" brand leather shoes go global.

Yu Xueyuan reminds

A new batch of influenza vaccine

Appointment vaccination has been opened.

Hurry up before the flu peak comes.

Arrange it for the children!

(Bao, it’s time for an injection)

Recently, a new batch (2023~2024 batches) of influenza vaccine has arrived in various places one after another, and it can be vaccinated by appointment.

On September 5th, China CDC suggested in the latest Technical Guide for Influenza Vaccination in China (2023-2024):

All people who are over 6 months old and have no contraindications should be vaccinated against influenza.

The CDC believes that

"This winter and next spring, you may face the risk of interaction or co-epidemic of respiratory infectious diseases such as COVID-19 and influenza."

In this situation, it is obviously necessary to vaccinate against influenza.

Is it too early to get a flu shot? How old can the child be vaccinated? How to choose several types of vaccines? ……There are still many concerns about the flu vaccine.

The following small series has compiled 9 frequently asked questions. Parents who are concerned about influenza vaccine should not miss today’s content ~

(Note: The new vaccination guide involves some updates and adjustments, and the following contents will also be popularized according to the new guide, so you may find that some information is different from what you have learned before, so it is recommended to take the new guide as the reference standard ~)

01

The flu vaccine is in place

Call now, is it early?

Say the answer first, not early, and just right.

Research data show that the epidemic season of influenza in winter and spring in China is usually from the middle and late October to the middle and early March of the following year.

After vaccination, the immune effect will not reach its peak until one month later.

According to the new guidelines: "The antibody protection level can be maintained for at least 6 months after influenza vaccination."

Vaccination now can just cover the upcoming peak of influenza in autumn and winter and the flu season in early spring next year.

When the flu peak comes, the antibody is just at the peak level, which can play a better protective effect.

02

The most important thing to vaccinate.

Who are they?

The new guidelines give priority to the timely vaccination of key and high-risk groups, including:

· Medical personnel, including clinical rescue personnel, public health personnel, health quarantine personnel, etc.;

·Older people aged 60 and over;

· People suffering from one or more chronic diseases;

· Vulnerable people and employees in old-age care institutions, long-term care institutions, welfare homes and other crowd gathering places;

· Pregnant women;

·Children aged 6-59 months (about 5 years old);

· Family members and caregivers of infants under 6 months old;

· People in key places such as kindergartens, primary and secondary schools, and supervision places.

Influenza vaccines are self-funded vaccines, but some areas have some free policies. Take Beijing as an example:

People over the age of 60, students in primary and secondary schools and emergency support personnel for major events can be vaccinated free of charge.

You can pay attention to the vaccination policy in your area.

03

What are the types of influenza vaccine?

How many shots? How to fight?

At present, there are trivalent inactivated influenza vaccine (IIV3), tetravalent inactivated influenza vaccine (IIV4) and trivalent live attenuated vaccine (LAIV3) approved for marketing in China, which are produced and supplied by different manufacturers.

In order to facilitate understanding, you can look at this table for specific vaccine types and applicable populations:

(Adults and children can refer to this table.)

Babies under the age of 6 months are also indirectly protected through the vaccination of their mothers during pregnancy and the vaccination of their caregivers and family members against influenza.

In order to gain sustained immunity,It is recommended that children be vaccinated against influenza once a year.Because the influenza virus is easy to mutate, the composition of the vaccine will be adjusted every year according to the prevalent strains of the year.

04

3 or 4, which is better?

Trivalent influenza vaccine can prevent influenza caused by influenza A (H1N1), H3N2 and Victoria B virus, while tetravalent influenza vaccine can alsoPrevent one more Yamagata virus B.

Source: Network

Although the virus coverage of tetravalent vaccine is wider than that of trivalent vaccine, the transmission ability and antigenic pathogenicity of influenza B virus are not as strong as that of influenza A virus.Therefore, vaccination with trivalent influenza vaccine can also prevent influenza virus.

There is no need for everyone to miss the best vaccination time in order to wait for the fourth price. After all,It is the most important thing to get vaccinated and protected in time!

05

Injection or nasal spray, which is better?

Whether it is injection or nasal spray, there is not much difference in safety and effectiveness.

You should notice that the injected vaccine is "inactivated" and the nasal spray is "attenuated". The difference lies in:

● Injection of influenza vaccine is to inactivate the virus, so that the virus loses its pathogenic ability but retains its antigenicity.

● Nasal spray vaccine is to culture and purify the live influenza virus, so that its virulence is weakened, but it can stimulate the human body to produce antibodies without pathogenic ability.

For babies who are very afraid of injections or dizzy needles, the nasal spray inoculation method is more moderate. But there is no need to pursue it deliberately. Again, timely vaccination is the most important thing.

06

The child has got the flu

Do you still need vaccination?

Need.

If the child accidentally gets the flu and has not been vaccinated against it before, he still needs to be vaccinated again after the baby gets better.

Because of influenza A,There is no cross-protection between different types.For example, if you have had H1N1 before, you will still get sick if you are infected with H3N2 next time.

07

Influenza vaccine can be combined with other vaccines

At the same time?

There are two situations.

Inactivated influenza vaccine (injection):Can be inoculated in different parts at the same time with other inactivated or attenuated influenza vaccines.

Attenuated vaccine (nasal spray):Can not be vaccinated with another attenuated vaccine at the same time, at least 4 weeks between them.

Can it be vaccinated at the same time as COVID-19 vaccine?

Over the age of 18, you can get inactivated influenza vaccine and COVID-19 vaccine at the same time;

Under the age of 18, it is recommended that the vaccination interval be greater than 14 days.

08

Taboos for influenza vaccination

Can egg allergy be vaccinated after all?

Egg allergy can be vaccinated against influenza.

People’s Republic of China (PRC) Pharmacopoeia (2010 edition, 2015 edition and 2020 edition) does not take people who are allergic to eggs as a taboo for vaccination.

The real vaccination taboos are the following!

You can’t get any flu vaccine.

(1) Those who are allergic to any ingredients contained in the vaccine (including auxiliary materials, formaldehyde, cracking agents and antibiotics) or have a history of severe allergic reaction to any kind of influenza vaccination.

(2) Patients suffering from acute diseases, severe chronic diseases or acute attacks of chronic diseases and fever are advised to be vaccinated after recovery or stable control.

(3) Guillain-Barre syndrome occurred within 6 weeks after previous influenza vaccination, which needs to be evaluated by a doctor.

Can’t be vaccinated with nasal spray attenuated influenza vaccine.

(1) Persons with low immune function due to drug use, HIV infection and other reasons.

(2) Children and adolescents treated with drugs containing aspirin or salicylic acid for a long time.

(3) Children with asthma aged 2-4 years.

(4) Have a history of Guillain-Barre syndrome.

(5) antiviral drugs such as oseltamivir and zanamivir were used 48 hours before inoculation, or palamivir was used 5 days before inoculation, or balosha was used 17 days before inoculation.

(6) In case of severe nasal congestion, it is suggested to suspend the inoculation of attenuated vaccine by nasal spray.

(7) Children with cochlear implants should avoid using nasal spray attenuated vaccine one week before and two weeks after operation.

(8) Pregnant women

There are still many contraindications for nasal spray attenuated vaccine.ofBefore choosing to vaccinate your child, you must pay attention to the above situation.

09

After vaccination

Will you still get the flu?

Maybe.

No vaccine can prevent the disease 100%, but vaccination can reduce the risk of infection andGreatly reduce the risk of serious illness and death.

According to the research data mentioned in the new guide, when influenza and COVID-19 are co-epidemic, after vaccination,At least it can achieve more than 70% protection effect.

Therefore, if no contraindications are involved, it is recommended to vaccinate in time, especially for the elderly and children.

Even if you are vaccinated against influenza, everyone should pay attention to prevention and maintain good hygiene habits.

Wash your hands frequently, ventilate frequently, go to crowded places less, wear masks when going to crowded places, and cover your nose and mouth when sneezing.

If you don’t know where to get a vaccine, you can refer to the following ways:

(1) Gaode or 114 inquires the telephone number of local hospitals, communities and epidemic prevention stations, and makes a phone call to consult about seedlings;

(2) Pay attention to WeChat official account, a local hospital, community and epidemic prevention station, and check whether there is an entrance for online seedling appointment;

（3）微信内搜索【疫苗服务预约】，选择所在城市，根据分类预约。

另外，育学园旗下北京弘和妇产医院也可约苗，在北京的朋友想了解可以拨打电话咨询??

咨询电话：(010)6549 1911

对流感疫苗还有其他问题，可以评论留言，小编会积极给大家解答~

最后，记得戳戳【在看】，和小编一起提醒大家，该！打！疫！苗！啦！

参考资料:

[1]中国疾病预防控制中心《中国流感疫苗预防接种技术指南（2023-2024）》

[2]上海疾控《流感疫苗可以安排了，给身体留出足够时间做准备》

[3]北京日报

免责声明：本文内容更新于2023年。文章仅提供一般的医疗、健康、用药、养育等方面的科普信息，不能代替任何个人的医学诊断和治疗。个人的医疗、用药问题请咨询医生。

授权转载：原创内容，欢迎转发，转载请留言。

01

这个孩子抹上脸的东西，可能导致性早熟！家里有的赶紧扔！

02

挨骂也要说，这种油别再吃了，家里有的赶紧扔！

03

扩散！这种家电每天都在释放「大量致癌物」！赶快提醒家里人

阅读原文」，下载育学园APP

Investment & Pensions Europe(IPE), an internationally renowned financial media organization, officially released the list of "Top 500 Asset Managers 2023".

The top 10 institutions in global asset management are BlackRock, Pioneer Pilot, Fidelity, State Street Global, Morgan Asset Management, Goldman Sachs Asset Management, Capital Group, Credit Suisse Oriental, Pinhao and new york Mellon Asset Management. There are 41 asset management institutions in China on the list, with excellent overall performance and greatly improved scale and ranking.

"Top 500 Global Asset Management Institutions List" is one of the annual reports of IPE. Headquartered in London, England, IPE is a well-known European financial media organization affiliated to IPE International Publishers Media Group, and enjoys a high reputation among global institutional investors and pension operators. IPE publishes authoritative lists such as the top 500 global asset management companies through market open data every year, and launches trend development reports, which has become an important vane in the global asset management field.

Top 20 of Global Asset Management 500 in 2023

Rank the total management scale of the headquarters of the asset management company at the end of 2022.

1. BlackRock US$ 8,052.9 billion.

2. Vanguard Investment Management US$ 6,743.3 billion.

3. Fidelity Investments US$ 3,653.6 billion.

4. State Street Global Advisors US$ 3,262.1 billion.

5. J.P.Morgan Asset Management US$ 2,616.4 billion.

6. Goldman Sachs Asset Management International US$ 2,152.1 billion.

7. Capital Group (US$ 2,044.3 billion)

8. Amundi France’s $1,904 billion.

9. PIMCO US/Germany USD 1,631.1 billion.

10. new york Mellon Asset Management US$ 1,615 billion.

11. Legal & General Investment Management UK $1,351.1 billion.

12. Jing Shun US/UK $1,320.7 billion.

13. Franklin Templeton US$ 1,296.4 billion.

14. Prudential Investment Management (PGIM) US$ 1,290.6 billion

15. Morgan Stanley Investment Management US$ 1,222.4 billion.

16. T. Rowe Price US$ 1,194.4 billion.

17. Wellington Management International US$ 1,082.4 billion.

18. Natixis Investment Management of France: US$ 1,078.8 billion.

19. Nuveen US$ 1,018.2 billion.

20. UBS Asset Management (UBS Asset Management) Switzerland 996.7 billion US dollars.

41 listed asset management companies in China

Rank company name

31. China Life Asset Management Co., Ltd.

36. Ping An Asset Management Co., Ltd.

64. Taikang Asset Management Co., Ltd.

E Fund Management Co., Ltd.

71. CMB Finance Co., Ltd. 85. Xingyin Finance Co., Ltd.

91. Jianxin Wealth Management Co., Ltd.

97. southern fund Management Company Limited.

99. Huaxia Fund Management Co., Ltd.

100. Agricultural Bank of China Finance Co., Ltd.

102. ICBC Wealth Management Co., Ltd.

103. BOC Wealth Management Co., Ltd.

ICBC Credit Suisse Fund Management Co., Ltd.

106. harvest fund Management Co., Ltd.

110. Guangfa Fund Management Co., Ltd.

112. Boss Fund Management Co., Ltd.

113. Xinyin Wealth Management Co., Ltd.

119. Pacific Asset Management Co., Ltd.

120. Xinhua Asset Management Co., Ltd

China Merchants Fund Management Co., Ltd.

122. China PICC Asset Management Co., Ltd.

124. Jianxin Fund Management Co., Ltd.

126. CITIC Securities Co., Ltd.

131. Fuguo Fund Management Co., Ltd.

142. Taiping Asset Management Co., Ltd.

145. Everbright Financial Management Co., Ltd.

151. Tianhong Fund Management Co., Ltd

153. Huitianfu Fund Management Co., Ltd

154. Penghua Fund Management Co., Ltd.

155, Yangtze River Pension Insurance Co., Ltd.

158. Bank of Communications Wealth Management Co., Ltd.

166. Everyone Asset Management Co., Ltd.

186, Yin Hua Fund Management Co., Ltd.

190, Ping An Finance Co., Ltd.

191. Minsheng Financial Management Co., Ltd.

194. Puyin Wealth Management Co., Ltd.

197. China Post Finance Co., Ltd.

200. cathay pacific fund Management Co., Ltd.

202. Sunshine Asset Management Co., Ltd.

208. Huatai Asset Management Co., Ltd.

210. China International Capital Corporation Limited

Contact PR Newswire

+86-10-5953 9500

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Original title: "The list of the top 500 global asset management institutions in 2023 was announced, and 41 Chinese state-owned assets management institutions were on the list | List 1"

Read the original text

　　In 2018, a realistic Dying to Survive hit a 3.1 billion summer box office champion. While countless people are sighing and moving, how to make the "sky-high life-saving medicine" accessible to ordinary patients has become a topic of general public concern.

　　The leukemia drug in this film — — Gleevec (imatinib mesylate) is a microcosm of high-priced drugs. This drug developed by Novartis Pharmaceutical entered China in early 2004, and the price of the original drug was as high as.23,500 yuan(120 tablets/box).

　　According to the first financial reporter, in the past decade, more and more manufacturers have entered the market of leukemia treatment drugs, making the price of this "life-saving medicine" drop again and again.

　　According to the data of CHIS kaisi system of Zhongkang Technology, the retail terminal price of Gleevec has been declining in the past three years, and the retail market price in 2022 will be6449.32 yuan. The reporter saw on an e-commerce platform on July 22 that the price of Gleevec’s original drug was mostly1700 yuan ~1800 yuanBetween

　　With the approval of more and more domestic generic drugs, the lowest price of domestic imatinib mesylate tablets has dropped to.144 yuan/boxIt is about 1.2% of the original price of the drug. At present, the sales price of Gleevec on the e-commerce platform is more than 1,700 yuan, which is nearly 90% lower than when Novartis first entered the China market.

　　The price of "life-saving medicine" continues to drop.

　　On July 19th, Hubei Provincial Medical Insurance Bureau posted a Notice on Publicizing the Information about the First to Fifth Batch of Non-selected Varieties in Centralized Drug Purchase by the State Organization, which stated that the first to fifth batches of centralized drug purchase by the State Organization had been carried out with the non-selected varieties under the generic name over-evaluated, the online price adjusted, the online suspension and the handling of complaints. On this basis, the medical insurance payment standard and other related work were drawn up, and a list of non-selected varieties to be online was formed. The publicity date of this list is from July 19 to July 23, 2023.

　　The online price of drugs refers to the published price of drugs on the centralized procurement platform of medical equipment in Hubei Province for the procurement of public medical institutions in the province. According to the regulations, all public medical institutions in Wuhan must purchase the drugs that have been hung on the net through the provincial centralized procurement platform for medical equipment when implementing the online procurement policy, and must not purchase from offline and other non-prescribed channels. The price of drugs hanging on the net is the highest price limit of public medical institutions in the city.

　　The list of the first batch of non-selected varieties to be hung on the net shows that there are6 imatinib mesylateAmong them, in addition to the original research drug Novartis Pharmaceutical, there are also five models, namely Zhengda Tianqing, Jiangsu Haosen, Qilu Pharmaceutical, Chongqing Yaoyou and Sinopharm Yixin, all of which have been evaluated.

　　In terms of price, the highest hanging net is still Gleevec.7182 yuan. Zhengda Tianqing, Jiangsu Haosen, Qilu Pharmaceutical and Sinopharm are all interested in imatinib mesylate. The online price is only.More than 500Yuan.

　　Even if the net price is 7,182 yuan, the price of the original drug Gleevec has dropped by nearly 40% compared with 23,500 yuan (120 tablets/box) when it first entered the China market.

　　According to the data of CHIS kaisi system of Zhongkang Technology, although the price of Gleevec in the hospital has remained at around 7182 yuan in the past three years, the price of retail terminals has been declining. In 2022, the retail market price will be6449.32 yuan.

　　The reporter’s search for "imatinib mesylate" on an e-commerce platform shows that the price of Gleevec’s original drug is only 0.1g*60 tablets/box as the standard in most pharmacies.1700 yuan ~1800 yuanBetween, and the price of domestic medicine is in500 yuanAbout. For example, the price of Xinwei tablets in Jiangsu Haosen is 430 yuan, the price of Genico capsules in Zhengda Tianqing is 441.88 yuan, and the lowest price is Shengdika tablets produced by Chongqing Shenghuaxi Pharmaceutical Co., Ltd., with an estimated hand price of 144 yuan.

　　nineDomestic companies were approved for production.

　　More and more cheap domestic "life-saving drugs" appeared, which was related to the end of the protection period of the compound patent of imatinib in China in April 2013, and domestic generic drugs began to be produced and listed.

　　From June 2013 to October 2014, three domestic generic drugs of Jiangsu Haosen, Zhengda Tianqing and Shiyao Ouyi obtained production approval. Because the efficacy of generic drugs has not been verified, the original drug of Novartis, Gleevec, still occupied most of the market. According to public data, in 2016, imatinib mesylate tablets sold more than 4 billion US dollars worldwide.

　　The competitiveness of domestic drugs began to improve after 2018. From 2018 to 2020, the above three drugs passed the consistency evaluation successively. On July 5, 2018, Jiangsu Haosen Pharmaceutical Co., Ltd. said that it had received the Approval Document for Supplementary Application of Imatinib, a chemical drug approved and issued by National Medical Products Administration, and the National Drug Testing Center recommended that it pass the consistency evaluation, making it the first enterprise to pass the consistency evaluation of this drug.

　　Overevaluation means that drugs have reached the passing line in quality and efficacy, and generic drugs have become more competitive. In September 2018, Hansen Pharmaceutical (Haosen Pharmaceutical) disclosed the prospectus for listing in Hong Kong, showing that the sales revenue of the core product imatinib mesylate in 2017 was RMB 2.5 billion, up by 7.3% since 2016, and up to June 30, 2018, up by 34.5% compared with the same period of last year.

　　With the entry of imatinib mesylate tablets into the medical insurance catalogue in 2017, more manufacturers entered this field. National Medical Products Administration website shows that the domestic imatinib mesylateNine manufacturers have been approved.Unacon Ouyi Pharmaceutical, Zhengda Tianqing, Qilu Pharmaceutical, Shenzhen Xinlitai Pharmaceutical, Chongqing Yaoyou Pharmaceutical, Lianyungang Runzhong Pharmaceutical, Shanghai Nuochuang Pharmaceutical, Fujian Nanfang Pharmaceutical and Chongqing Shenghuaxi Pharmaceutical, among which Shanghai Nuochuang Pharmaceutical and Fujian Nanfang Pharmaceutical successivelyMay and June this yearJust approved.

　　What followed was that prices kept falling.

　　In 2018, imatinib mesylate tablets of Jiangsu Haosen Pharmaceutical Co., Ltd. won the bid in four municipalities directly under the Central Government, including Beijing, Tianjin, Shanghai and Chongqing, and 11 cities (referred to as "4+7" cities) including Shenyang, Guangzhou, Chengdu and Xi ‘an, with the winning price of 623.82 yuan per box. In 2019, the "4+7" procurement expanded, and Zhengda Tianqing won the bid at a price of 586.39 yuan, further reducing the price of this drug.

　　In August, 2022, Shanghai issued a price adjustment notice, and the adjusted purchase price of imatinib mesylate tablets produced by Shiyao Ouyi has dropped to 180 yuan/box.

　　The lower price of domestic drugs also impacts the price of original drugs.

　　In 2018, the joint bargaining of imported anticancer drugs in 14 provinces including Shaanxi was completed, and 47 anticancer drugs including Gleevec were successfully negotiated. According to the announcement, the bargaining result of Gleevec’s specification of 0.1g*60 tablets was 9998 yuan.

　　In 2019, according to the previous report of CBN, the price of the original drug Gleevec in Shanghai has dropped to 7182 yuan/box, which is about 30% lower than the market price of around 11,000 yuan at that time.

　　New progress

　　It is worth mentioning that with the increase of drug resistance caused by long-term medication, Gleevec’s R&D iteration has also attracted much attention.

　　The second and third generation BCR-ABL inhibitors have been developed in order to solve the drug resistance problem and improve the safety. Dashatinib from Bristol-Myers Squibb and Nilotinib from Novartis were introduced one after another, which made the second generation BCR-ABL inhibitors gradually occupy an important position in the first-line and second-line treatment of chronic myeloid leukemia. However, the problem of drug resistance still exists during the use of the second generation BCR-ABL inhibitors.

　　In November, 2021, Nilik, known as the "third generation Gleevec" made in China, was approved for marketing in National Medical Products Administration, China, and was used to treat adult patients who were resistant to any tyrosine kinase inhibitor (TKI) and were diagnosed as chronic myeloid leukemia (CML) with T315I mutation in chronic phase (CP) or accelerated phase (AP) by fully verified detection methods.

　　This year, on July 6th, Yasheng Medical Officer Wei announced that Nilik had obtained the clinical trial permission from National Medical Products Administration Drug Evaluation Center, and would carry out a key registered phase III clinical trial of combined chemotherapy compared with imatinib combined chemotherapy in the treatment of newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia (referred to as "Ph+ALL").

　　At the end of 2022, Novartis decided not to be responsible for the sales promotion of Gleevec in China.

　　The official micro-display of Sinopharm Holdings shows that from January 1, 2023, Sinopharm Holdings officially obtained the commercial promotion right of Novartis Gleevec in China market. Xie Jiong, director of the Drug Shield Public Welfare Fund, said in an interview with the media that for many drugs, it is necessary to adjust the inherent marketing model after a certain development cycle, so as to drive the second peak of sales. This will not only prolong the life cycle of drug sales, but also greatly enhance the accessibility of drugs and benefit a wider range of patients.

　　Our reporter Lin Zhiyin also contributed to this article.

CCTV News:The Paris Olympic Games is in full swing, and the spirit of Olympic athletes’ tenacious struggle and self-breakthrough in the Olympic Games is inspiring. The TV programs of the Paris Olympic Games of the Central Radio and Television General Station were broadcast live in more than 800 cinemas across the country, attracting many viewers to watch the games.

On the evening of August 4th, Beijing time, the men’s singles table tennis final of the Paris Olympic Games began, and China’s Fan Zhendong played against Sweden. In a movie theater on BeijingRoad, Guangzhou, the audience cheered for China’s Fan Zhendong.

There is a strong atmosphere in the cinema to watch the Olympic Games. When the games enter a stalemate, the audience hold their breath and say hello. When the China athletes scored a point, the audience cheered loudly and waved flags to cheer.

In the end, Fan Zhendong won 4-1, winning the third gold medal for the China table tennis team. When the national flag was raised and the national anthem was played, all the audience in the cinema stood up and sang the national anthem, and their hearts surged.

Watching the Olympics in cinemas: covering more than 800 cinemas in Beijing, Shanghai, Shenzhen and Chengdu.

"Watching the Olympics in the cinema" is the first time in China to broadcast the Olympic Games live on the cinema screen. At the same time, the Olympic Games were broadcast on the main station "100 cities and 1000 screens". The audience felt the fighting style of Olympic athletes in the diverse scenes between domestic cinemas and urban streets.

The film list of the live broadcast of "Watching the Olympics in the Cinema" was attended by the China team and at 18: 00 Beijing time — The popular games that started at 21: 00 are mainly, covering more than 800 cinemas in Beijing, Shanghai, Shenzhen, Chengdu and other cities. Among them, table tennis, badminton, women’s volleyball and other traditional advantage events of China delegation were welcomed by the audience.

The introduction of the Olympic Games into cinemas not only provides a new channel for the masses to watch the Paris Olympic Games, but also builds a new platform for the audience to appreciate the elegance of China athletes, feel the spirit of sports and unite national feelings.

In addition, this year’s Paris Olympic Games brought a brand-new watching experience to the national audience with the help of the general station "100 cities and 1000 screens". Through 1075 ultra-high-definition large screens of diversified scenes such as core business districts, city squares and transportation hubs in 112 cities including Tianjin, Shanghai, Fujian and Sichuan, the contents of 8k ultra-high-definition Olympic Games will be continuously broadcast, so that urban audiences can share the wonderful moments of this sports feast.

In the [Easy Car Taiyuan Local Car Market Promotion Channel], we sorted out the ongoing
Preferential activities. As a car model that has attracted much attention, the current discount rate of Star Road Chasing Wind is still very amazing. The highest discount rate can even reach 0.70 million, and the lowest starting price is only 102,900. You can win a larger discount rate by clicking the "Inquiry" button in the quotation form. If you are looking for a practical and affordable model, you may wish to learn about the preferential situation of chasing the wind by the stars.

Let’s take a look at the appearance of Starway Chasing Wind. The design style of Starway Chasing Wind’s front face has taken a sharp line, and it looks very tough with multi-frame air intake grille. At the same time, the headlight presents a beautiful design style, and the visual effect looks quite clean and refreshing. The car is equipped with LED daytime running lights, headlight height adjustment, delay closing and so on. Come to the side of the car, the car body size is 4538MM*1848MM*1699MM, the car uses rounded lines, the car side gives a very capable feeling, with large-size thick-walled tires, eye-catching shape. In the rear part, the tail line of Starway Chasing the Wind is young, the taillights are very concise, and the exhaust pipe uses the design of bilateral double outlet, so the overall shape is still very attractive.

When I came into the car, the interior styling looked very cool and the overall design was very individual. The steering wheel of the car is very soft in shape, made of leather, and has a good grip. Take a look at the central control. The car is decorated with a lovely touch-sensitive LCD central control screen, which makes the interior design quite layered and very consistent with the temperament of the car. Finally, let’s look at the dashboard and seats. The dashboard design is remarkable and the design is sharp. The car uses a leather-like seat, the seat is wrapped in place, and the overall ride feels soft and comfortable.

Starway Chasing Wind matches CVT gearbox, with an acceleration time of 9.7s per 100 kilometers, which has good power performance and is completely OK for daily use.

Starway Chasing the Wind is an excellent model, and its dynamic performance is impressive. During the test drive, the acceleration response of the vehicle is rapid, especially when driving at high speed, it can still maintain strong power output. At the same time, the energy consumption performance of this car is also very satisfactory, which not only saves fuel expenses, but also contributes to environmental protection. In addition, the overall space performance is excellent, and both front and rear passengers can get a spacious and comfortable ride experience. Generally speaking, the Star Road Chasing Wind is a very cost-effective model, which is worth recommending to buy.

The Beijing News Shell Financial News (Reporter Lin Zi) On April 15th, the Star Era Night and Star Era ET Pre-sale Conference was held. There are two kinds of pure electric versions and extended range versions of ET in this Star Age, namely REEV series: 199,000 yuan for Plus, 219,000 yuan for Pro and 239,000 yuan for Pro, and BEV series: 239,000 yuan for Pro, 249,000 yuan for Pro Four-wheel Drive, 259,000 yuan for Pro City Smart Drive, 289,000 yuan for Max and 329,000 yuan for Ultra32.9

The longest cruising range of Xingjiyuan ET pure electric version is 760km, and the comprehensive cruising range of extended range version is over 1500km.

The extended-range version adopts a special engine with the highest thermal efficiency of 44.5% in industrial mass production developed by Chery, with a rated power of 115kW, achieving 1L oil power generation of 3.65kWh and WLTC feed fuel consumption of 5.2L/100km.

The pure electric version is equipped with Contemporary Amperex Technology Co., Limited Shenxing rechargeable battery, with a peak charging power of 420kW, which can achieve a battery life of 475km for 11.5 minutes. Even in the low temperature environment of-20℃, it only takes 24 minutes for the SOC to change from 20% to 80%. When the SOC is only 20%, the peak output power still reaches 280kW.

Editor Jiang Fan

Proofread Jia Ning

1905 movie network news At the end of January, the high-profile announcement of remarriage was good news, and his wife was pregnant. A few days ago, the husband and wife made a high-profile appearance at the airport and flew to Hungary together. Their beloved wife will accompany him to film here. Song Joong Ki, who hasn’t shared her recent life for a long time, updated the IG news on February 19th, and published her first PO article after remarriage.

Song Joong Ki exposed his daily life in Hungary. He was in a sunny bathroom, enjoying a pleasant time with his dog in his arms and pouting and kissing. Although my beloved wife didn’t appear, it is not difficult to see the silhouette of a woman from the reflection on the wall. Some netizens speculated that it should be Katie in love plus.

It is reported that Song Joong Ki went to Hungary this time to shoot a new film "The End of Roadbed". Originally, it was speculated that Katie would give birth in South Korea. Unexpectedly, the two of them appeared at the airport on the 16th, and Katie also took her dog abroad. A family of four made a surprise appearance and became the focus of the spotlight.

"Lu Jiwan" tells the love story of Lu Jiwan, a defector who arrived in Belgium with the last glimmer of hope, meeting and breaking up with Mary, a Korean woman who lost her reason to live. In the film, Song Joong Ki plays Lu Jiwan, a defector from the North, and strives for refugee status in Belgium. According to the plan, the film will be finished in June this year.